[Table], Table 4. Lineage Assignment Criteria for Mixed Phenotype Acute Leukemia According to the 2016 Revision to the World Health Organization Classification of Myeloid Neoplasms and Acute Leukemiaa - PDQ Cancer Information Summaries - NCBI Bookshelf

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Table 4. Lineage Assignment Criteria for Mixed Phenotype Acute Leukemia According to the 2016 Revision to the World Health Organization Classification of Myeloid Neoplasms and Acute Leukemia^a

Lineage	Criteria
Myeloid lineage	Myeloperoxidase (flow cytometry, immunohistochemistry, or cytochemistry); or monocytic differentiation (at least two of the following: nonspecific esterase cytochemistry, CD11c, CD14, CD64, lysozyme)
T lineage	Strong^b cytoplasmic CD3 (with antibodies to CD3 epsilon chain); or surface CD3
B lineage	Strong^b CD19 with at least one of the following strongly expressed: CD79a, cytoplasmic CD22, or CD10; or weak CD19 with at least two of the following strongly expressed: CD79a, cytoplasmic CD22, or CD10

: ^aAdapted from Arber et al.[104]
: ^bStrong defined as equal to or brighter than the normal B or T cells in the sample.

From: Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®)

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