Table 1. National Cancer Institute's Common Terminology Criteria for Adverse Events: Diarrheaa,b

GradeDescription
1Increase of <4 stools/day over baseline; mild increase in ostomy output compared with baseline
2Increase of 4–6 stools/day over baseline; moderate increase in ostomy output compared with baseline
3Increase of ≥7 stools/day over baseline; incontinence; hospitalization indicated; severe increase in ostomy output compared with baseline; limiting self-care ADLc
4Life-threatening consequences; urgent intervention indicated
5Death

ADL = activities of daily living.

aAdapted from National Cancer Institute.[8]

bDefinition: A disorder characterized by frequent and watery bowel movements.

cSelf-care ADL refers to bathing, dressing and undressing, feeding self, using the toilet, taking medications, and not bedridden.

From: Gastrointestinal Complications (PDQ®)

Cover of PDQ Cancer Information Summaries
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.