From: Childhood Liver Cancer Treatment (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 7. Conditions Associated With Hepatocellular Carcinoma
| Associated Disorder | Clinical Findings |
|---|---|
| Alagille syndrome [4] | Broad prominent forehead, deep-set eyes, and small prominent chin. Abnormality of bile ducts leads to intrahepatic scarring. For more information, see the Alagille syndrome section. |
| Glycogen storage diseases I–IV [5] | Symptoms vary by individual disorder. |
| Hepatitis B and C [6-8] | For more information, see the Hepatitis B and hepatitis C infection section. |
| Progressive familial intrahepatic cholestasis [9,10] | Symptoms of jaundice, pruritus, and failure to thrive begin in infancy and progress to portal hypertension and liver failure. |
| Tyrosinemia [11] | First few months of life: failure to thrive, vomiting, jaundice. |