| Tumor type | Estimated Penetrance | Symptoms |
|---|---|---|
| Prolactinoma | 20% [18] | Galactorrhea |
| Amenorrhea/infertility | ||
| Hypogonadism | ||
| Somatotropinoma | 10% [18] | Coarse facial features |
| Soft tissue overgrowth: enlargement of hands/feet | ||
| Hyperhidrosis | ||
| Corticotropinoma | <5% [18] | Weight gain |
| Hypertension | ||
| Flushing | ||
| Easy bruising/bleeding | ||
| Hyperglycemia |
MEN1 = multiple endocrine neoplasia type 1.
From: Genetics of Endocrine and Neuroendocrine Neoplasias (PDQ®)
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