From: Genetics of Skin Cancer (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 6. Genes Associated with Fanconi Anemia (FA)
| Gene | Locus | Approximate Incidence Among FA Patients (%) | Pattern of Disease Transmission |
|---|---|---|---|
| FANCA (OMIM) | 16q24.3 | ~70 | AR |
| FANCB (OMIM) | Xp22.31 | Rare | XLR |
| FANCC (OMIM) | 9q22.3 | ~10 | AR |
| FANCD1 (BRCA2) (OMIM) | 13q12.3 | Rare | AR |
| FANCD2 (OMIM) | 3p25.3 | Rare | AR |
| FANCE (OMIM) | 6p21.3 | ~10 | AR |
| FANCF (OMIM) | 11p15 | Rare | AR |
| FANCG (XRCC9) (OMIM) | 9p13 | ~10 | AR |
| FANCI (KIAA1794) (OMIM) | 15q25-26 | Rare | AR |
| FANCJ (BACH1/BRIP1) (OMIM) | 17q22.3 | Rare | AR |
| FANCL (PHF9/POG) (OMIM) | 2p16.1 | Rare | AR |
| FANCM (Hef) (OMIM) | 14q21.3 | Rare | AR |
| FANCN (PALB2) (OMIM) | 16p12.1 | Rare | AR |
| FANCO (RAD51C) (OMIM) | 17q22 | Rare | AR |
| FANCP (SLX4/BTBD12) (OMIM) | 16p13.3 | Rare | AR |
| FANCQ (ERCC4/XPF) (OMIM) | 16p13.12 | Rare | AR |
| FANCS (BRCA1) (OMIM) | 17q21.31 | Rare | AR |
AR = autosomal recessive; XLR = X-linked recessive.