From: Genetics of Skin Cancer (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 7. Genes Associated with Fanconi Anemia (FA)
| Gene | Locus | Approximate Incidence Among FA Patients (%) | Pattern of Disease Transmission |
|---|---|---|---|
| FANCA | 16q24.3 | 70 | AR |
| FANCB | Xp22.31 | Rare | XLR |
| FANCC | 9q22.3 | 10 | AR |
| FANCD1 (BRCA2) | 13q12.3 | Rare | AR |
| FANCD2 | 3p25.3 | Rare | AR |
| FANCE | 6p21.3 | 10 | AR |
| FANCF | 11p15 | Rare | AR |
| FANCG (XRCC9) | 9p13 | 10 | AR |
| FANCI (KIAA1794) | 15q25-26 | Rare | AR |
| FANCJ (BACH1/BRIP1) | 17q22.3 | Rare | AR |
| FANCL (PHF9/POG) | 2p16.1 | Rare | AR |
| FANCM (Hef) | 14q21.3 | Rare | AR |
| FANCN (PALB2) | 16p12.1 | Rare | AR |
| FANCO (RAD51C) | 17q22 | Rare | AR |
| FANCP (SLX4/BTBD12) | 16p13.3 | Rare | AR |
| FANCQ (ERCC4/XPF) | 16p13.12 | Rare | AR |
| FANCS (BRCA1) | 17q21.31 | Rare | AR |
AR = autosomal recessive; XLR = X-linked recessive.