From: Malignant Mesothelioma Treatment (Adult) (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 1. Definitions of TNM Stages IA and IBa
| Stage | TNM | Description |
|---|---|---|
| IA | T1, N0, M0 | T1 = Tumor limited to the ipsilateral parietal pleura with or without involvement of: |
| –visceral pleura. | ||
| –mediastinal pleura. | ||
| –diaphragmatic pleura. | ||
| N0 = No regional lymph node metastases. | ||
| M0 = No distant metastasis. | ||
| IB | T2 or T3, N0, M0 | T2 = Tumor involving each of the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least one of the following features: |
| –involvement of diaphragmatic muscle. | ||
| –extension of tumor from visceral pleura into the underlying pulmonary parenchyma. | ||
| T3 = Describes locally advanced but potentially resectable tumor. | ||
| Tumor involving all the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least one of the following features: | ||
| –involvement of the endothoracic fascia. | ||
| –extension into the mediastinal fat. | ||
| –solitary, completely resectable focus of tumor extending into the soft tissues of the chest wall. | ||
| –nontransmural involvement of the pericardium. | ||
| N0 = No regional lymph node metastases. | ||
| M0 = No distant metastasis. |
T = primary tumor; N = regional lymph node; M = metastasis.
aReprinted with permission from AJCC: Malignant Pleural Mesothelioma. In: Amin MB, Edge SB, Greene FL, et al., eds.: AJCC Cancer Staging Manual. 8th ed. New York, NY: Springer, 2017, pp 457–68.