From: Malignant Mesothelioma Treatment (Adult) (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 2. Definitions of TNM Stage IIa
| Stage | TNM | Description |
|---|---|---|
| II | T1, N1, M0 | T1 = Tumor limited to the ipsilateral parietal pleura with or without involvement of: |
| –visceral pleura. | ||
| –mediastinal pleura. | ||
| –diaphragmatic pleura. | ||
| N1 = Metastases in the ipsilateral bronchopulmonary, hilar, or mediastinal (including the internal mammary, peridiaphragmatic, pericardial fat pad, or intercostal) lymph nodes. | ||
| M0 = No distant metastasis. | ||
| T2, N1, M0 | T2 = Tumor involving each of the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least one of the following features: | |
| –involvement of diaphragmatic muscle. | ||
| –extension of tumor from visceral pleura into the underlying pulmonary parenchyma. | ||
| N1 = Metastases in the ipsilateral bronchopulmonary, hilar, or mediastinal (including the internal mammary, peridiaphragmatic, pericardial fat pad, or intercostal) lymph nodes. | ||
| M0 = No distant metastasis. |
T = primary tumor; N = regional lymph node; M = metastasis.
aReprinted with permission from AJCC: Malignant Pleural Mesothelioma. In: Amin MB, Edge SB, Greene FL, et al., eds.: AJCC Cancer Staging Manual. 8th ed. New York, NY: Springer, 2017, pp 457–68.