From: Retinoblastoma Treatment (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 9. AJCC Prognostic Stage Groups: Clinical Stage (cTNM)a
| When cT is... | And N is... | And M is... | And H is... | Then the clinical stage group is... |
|---|---|---|---|---|
| cT1, cT2, cT3 | cN0 | cM0 | Any | I |
| cT4a | cN0 | cM0 | Any | II |
| cT4b | cN0 | cM0 | Any | III |
| Any | cN1 | cM0 | Any | III |
| Any | Any | cM1 or pM1 | Any | IV |
cM = clinical distant metastasis; cN = clinical regional lymph node; cT = clinical primary tumor; H = heritable trait; pM = pathological distant metastasis.
aReprinted with permission from AJCC: Retinoblastoma. In: Amin MB, Edge SB, Greene FL, et al., eds.: AJCC Cancer Staging Manual. 8th Ed. New York, NY: Springer, 2017, pp. 819–831.