From: Adult Primary Liver Cancer Treatment (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 3. Definitions of TNM Stages IIIA and IIIBa
| Stage | TNM | Description |
|---|---|---|
| IIIA | T3, N0, M0 | T3 = Multiple tumors, at least one of which is >5 cm. |
| N0 = No regional lymph node metastasis. | ||
| M0 = No distant metastasis. | ||
| IIIB | T4, N0, M0 | T4 = Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein, or tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. |
| N0 = No regional lymph node metastasis. | ||
| M0 = No distant metastasis. |
T = primary tumor; N = regional lymph nodes; M = distant metastasis.
aReprinted with permission from AJCC: Liver. In: Amin MB, Edge SB, Greene FL, et al., eds.: AJCC Cancer Staging Manual. 8th ed. New York, NY: Springer, 2017, pp. 287–93.