Pirain-2005

Methods Cross sectional questionnaire study
Participants and Country 45 patients presenting to a obstetrics and gynaecology outpatient clinic
Interventions Ancillary immunohistochemistry tests to identify a primary tumour in CUP. Patients were asked to imagine they had either CUP or a previously diagnosed and treated breast cancer with a newly identified primary, after receiving information about the diagnostic performance of IHC, patients were asked how much they would be willing to pay for IHC analysis of their tumour when it would influence their survival, and also when it would not.
Outcomes Willingness to pay for additional immunohistochemistry tests
For both the CUP and breast cancer scenarios patients were willing to pay an average of $1900 for ancillary IHC tests. Respondents were willing to pay whether or not it made a difference to their clinical outcome, if it allowed them to know the origin of their tumour. Patients were willing to pay more for IHC tests with high diagnostic performance.
Notes Private healthcare setting. Patient group was not cancer of unknown primary

From: Guideline chapter 3, Factors Influencing Management

Cover of Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin
Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin.
NICE Clinical Guidelines, No. 104.
Copyright © 2010, National Collaborating Centre for Cancer.

No part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licenses issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.