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National Collaborating Centre for Nursing and Supportive Care (UK). Irritable Bowel Syndrome in Adults: Diagnosis and Management of Irritable Bowel Syndrome in Primary Care [Internet]. London: Royal College of Nursing (UK); 2008 Feb. (NICE Clinical Guidelines, No. 61.)
Update information March 2017 Recommendation 1.1.1.2 in the short version was updated by NICE with more recent guidance on recognition and referral for suspected cancer. Recommendation 1.1.1.3 in the short version was removed as it was no longer needed after the changes to recommendation 1.1.1.2. February 2015 NICE has made new recommendations relating to the clinical management (dietary and lifestyle advice, and pharmacological therapy) of people with IBS. The recommendations and evidence in sections 3, 7.6, 8.4, 8.5.2 and 9.1 of this guideline that have been highlighted in grey have been stood down and replaced. New recommendations on dietary and lifestyle advice, and pharmacological therapy, can be found in the irritable bowel syndrome in adults update CG61.1. September 2012 A recommendation in this guideline (see pages 28 and 37) has been partially updated by recommendation 1.1.2.1 in 'Ovarian cancer' (NICE clinical guideline 122, 2011).
Irritable Bowel Syndrome in Adults: Diagnosis and Management of Irritable Bowel Syndrome in Primary Care [Internet].
Show detailsEvidence Summary: antidepressants review
Comparison: tricyclics versus placebo
Evidence Summary: antimotiltiy agents review
Acute studies Comparison: co-phenotrope versus placebo
Acute studies Comparison: loperamide versus placebo
Acute studies Comparison: co-phenotrope versus loperamide
Acute studies Comparison: co-phenotrope versus morphine
Evidence Summary: anti-spasmodics review
Comparison: all antispasmodics vs placebo
Comparison: smooth muscle relaxant vs placebo
Evidence Summary: CBT review
Comparison: CBT versus placebo/no treatment/symptom monitoring
Comparison: CBT + medical treatment versus medical treatment
Evidence Summary: hypnotherapy review
Comparison: Hypnotherapy vs waiting list control
Evidence Summary: laxatives review
short term relief Comparison: stimulant laxative versus placebo (Bisacodyl versus placebo)
long term maintenance Comparison: osmotic laxative versus placebo (PEG versus placebo)
Comparison: osmotic laxative versus stimulant laxative (PEG versus Lactulose)
Comparison: Stimulant laxative 1 versus Stimulant laxative 2 (Bisacodyl versus sodium picosulphate)
Comparison: laxative dose 1 versus laxative dose 2 (standard dose versus maximum dose)
Comparison: laxative versus fibre (lactulose versus ispaghula)
Evidence Summary: psychotherapy review
Comparison: psychotherapy+medical vs medical
- Grading the evidence - Irritable Bowel Syndrome in AdultsGrading the evidence - Irritable Bowel Syndrome in Adults
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