1. Aaronson S.A., Jainchill J.L., Todaro G.J. Murine sarcoma virus transformation of BALB/3T3 cells: Lack of dependence on murine leukemia virus. Proc. Natl. Acad. Sci. 1970;66:1236–1243. [PMC free article: PMC335811] [PubMed: 4319884]
  2. Abe R., Hodes R. T cell recognition of minor lymphocyte stimulating (Mls) gene products. Annu. Rev. Immunol. 1989;7:683–708. [PubMed: 2496737]
  3. Abelson H.T., Rabstein L.S. Lymphosarcoma: Virus-induced thymic-independent disease in mice. Cancer Res. 1970;30:2213–2222. [PubMed: 4318922]
  4. Abkowitz J.L., Holly R.D., Adamson J.W. Retrovirus-induced feline pure red cell aplasia: The kinetics of erythroid marrow failure. J. Cell Physiol. 1987a;132:571–577. [PubMed: 2821017]
  5. Abkowitz J.L., Holly R.D., Grant C.K. Retrovirus-induced feline pure red cell aplasia. Hematopoietic progenitors are infected with feline leukemia virus and erythroid burst-forming cells are uniquely sensitive to heterologous complement. J. Clin. Invest. 1987b;80:1056–1063. [PMC free article: PMC442346] [PubMed: 2821071]
  6. Acha-Orbea H., MacDonald H.R. Superantigens of mouse mammary tumor virus. Annu. Rev. Immunol. 1995;13:459–486. [PubMed: 7612231]
  7. Acha-Orbea H., Scarpellino L., Shakhov A.N., Held W., MacDonald H.R. Inhibition of mouse mammary tumor virus-induced T cell responses in vivo by antibodies to an open reading frame protein. J. Exp. Med. 1992;176:1769–1772. [PMC free article: PMC2119446] [PubMed: 1334118]
  8. Ackley C.D., Yamamoto J.K., Levy N., Pedersen N.C., Cooper M.D. Immunologic abnormalities in pathogen free cats experimentally infected with feline immunodeficiency virus. J. Virol. 1990;64:5652–5655. [PMC free article: PMC248623] [PubMed: 1976826]
  9. Adams J.M., Cory S. Transgenic models of tumor development. Science. 1991a;254:1161–1167. [PubMed: 1957168]
  10. Adams J.M., Cory S. Transgenic models for haemopoietic malignancies. Biochem. Biophys. Acta. 1991b;107:29–31. [PubMed: 2018781]
  11. Adler H.T., Reynolds P.J., Kelley C.M., Sefton B.M. Transcriptional activation of lck by retrovirus promoter insertion between two lymphoid-specific promoters. J. Virol. 1988;62:4113–4122. [PMC free article: PMC253842] [PubMed: 2845126]
  12. Adler V., Franklin C.C., Kraft A.S. Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: Regulation by the N-terminal δ domain. Proc. Natl. Acad. Sci. 1992;89:5341–5345. [PMC free article: PMC49287] [PubMed: 1608942]
  13. Ahmed M., Korol W., Larson D.L., Harewood K.R., Mayyasi S.A. Interactions between endogenous baboon type-C virus and oncogenic viruses. I. Syncytium induction and development of infectivity assay. Int. J. Cancer. 1975;16:747–755. [PubMed: 171228]
  14. Akizuki S., Setoguchi M., Nakazato O., Yoshida S., Higuchi Y., Yamamoto S., Okajima T. An autopsy case of human T-lymphotropic virus type I-associated myelopathy. Hum. Pathol. 1988;19:988–990. [PubMed: 2900211]
  15. Amanuma H., Watanabe M., Nishi M., Ikawa Y. Requirement of the single base pair insertion at the 3′ end of the env-related gene of Friend spleen-focus forming virus for pathogenic activity and its effect on localization of the glycoprotein product (gp55). J. Virol. 1989;63:4824–4833. [PMC free article: PMC251120] [PubMed: 2552155]
  16. Amanuma H., Akiko K., Obata M., Sagata N., Ikawa Y. Complete nucleotide sequence of the gene for the specific glycoprotein (gp52) of Friend spleen focus-forming virus. Proc. Natl. Acad. Sci. 1983;80:3913–3917. [PMC free article: PMC394169] [PubMed: 6306650]
  17. Amati B., Brooks M.W., Levy N., Littlewood T.D., Evans G.I., Land H.J. Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell. 1993;72:233–245. [PubMed: 8425220]
  18. Andersen P.R., Barbacid M., Tronick S.R., Clark H.F., Aaronson S.A. Evolutionary relatedness of viper and primate endogenous retroviruses. Science. 1979;204:318–321. [PubMed: 219480]
  19. Anderson D.M., Lyman S.D., Baird S.D., Wignall J.M., Eisenman J., Rauch C., Marsch C.J., Boswell H.S., Gimpel S.D., Cosman D., Williams D.E. Molecular cloning of mast cell growth factor, hematopoietin that is active in both membrane bound and soluble forms. Cell. 1990;63:235–243. [PubMed: 1698558]
  20. Anderson L.J., Jarrett W.F., Jarrett O., Laird H.M. Feline leukemia virus infection of kittens: Mortality associated with atrophy of the thymus and lymphoid depletion. J. Natl. Cancer Inst. 1971;47:807–817. [PubMed: 5286051]
  21. Anderson L.W., Klevjer-Anderson P., Liggitt H.D. Susceptibility of blood-derived monocytes and macrophages to caprine arthritis-encephalitis virus. Infect. Immun. 1983;41:837–840. [PMC free article: PMC264717] [PubMed: 6307885]
  22. Ando Y., Nakano S., Saito K., Shiamoto I., Ichijo M., Toyama T., Hinuma Y. Transmission of adult T-cell leukemia retrovirus (HTLV-I) from mother to child: Comparison of bottle- with breast-fed babies. Jpn. J. Cancer Res. 1987;78:322–324. [PubMed: 2884205]
  23. Andrews J.M., Andrews R.L. 1976The comparative neuropathology of motor neuron diseases In Amyotrophic lateral sclerosis: Recent research trends (ed. J.M. Andrews et al.), pp. 181–216. Academic Press, New York. [PubMed: 191965]
  24. Andrews J.M., Gardner M.B. Lower motor neuron degeneration associated with type C RNA virus infection in mice: Neuropathological features. J. Neuropathol. Exp. Neurol. 1974;33:285–307. [PubMed: 4362701]
  25. Aronheim A., Engelberg D., Li N., Schlessinger J., Karin M. Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. Cell. 1994;78:949–961. [PubMed: 7923364]
  26. Arthur L.O., Gilden R.V., Marx P.A., Gardner M.B. Simian acquired immunodeficiency syndrome. Prog. Allergy. 1986;37:332–352. [PubMed: 3960863]
  27. Arya S.K., Wong-Staal F., Gallo R.C. T-cell growth factor gene: Lack of expression in human T-cell leukemia-lymphoma virus infected cells. Science. 1984;223:1086–1087. [PubMed: 6320374]
  28. Asher D.M., Goudsmit J., Pomeroy K.L., Garruto R.M., Bakker M., Ono S.G., Elliott N., Harris K., Askins H., Eldadah Z., Goldstein A.D., Gadjusek D.C. Antibodies to HTLV-I in populations of the southwestern Pacific. J. Med. Virol. 1988;26:339–351. [PubMed: 3209991]
  29. Asjo B., Skoog L., Palminger I., Weiner F., Isaak D., Cerny J., Fenyo E.M. Influence of genotype and the organ of origin on the subtype of T-cell in Moloney lymphomas induced by transfer of preleukemic cells from athymic and thymus-bearing mice. Cancer Res. 1985;45:1040–1045. [PubMed: 3871660]
  30. Askew D.S., Li J., Ihle J.N. Retroviral insertions in the murine His-1 locus activate the expression of a novel RNA that lacks an extensive open reading frame. Mol. Cell. Biol. 1994;14:1743–1751. [PMC free article: PMC358532] [PubMed: 8114708]
  31. Askew D.S., Bartholomew C., Buchberg A.M., Valentine M.B., Jenkins N.A., Copeland N.G., Ihle J.N. His1 and His2: Identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia. Oncogene. 1991;6:2041–2047. [PubMed: 1682866]
  32. Athas G.B., Lobelle-Rich P., Levy L.S. Function of a unique sequence motif in the long terminal repeat of feline leukemia virus isolated from an unusual set of naturally occurring tumors. J. Virol. 1995;69:3324–3332. [PMC free article: PMC189044] [PubMed: 7745680]
  33. Aurigemma R.E., Comstock R.D., Smith R.E. Persistent viral DNA synthesis associated with an avian osteopetrosis-inducing virus. Virology. 1989;171:626–629. [PubMed: 2548335]
  34. Ayer D.E., Kretzner L., Eisenman R.N. Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity. Cell. 1993;72:211–222. [PubMed: 8425218]
  35. Aziz D.C., Hanna Z., Jolicoeur P. Severe immunodeficiency disease induced by a defective murine leukemia virus. Nature. 1989;338:505–508. [PubMed: 2538760]
  36. Baba T.W., Humphries E.H. Avian leukosis virus infection: Analysis of viremia and DNA integration in susceptible and resistant chicken lines. J. Virol. 1984;51:123–130. [PMC free article: PMC254409] [PubMed: 6328031]
  37. Baba T.W., Humphries E.H. Formation of a transformed follicle is necessary but not sufficient for development of an avian leukosis virus-induced lymphoma. Proc. Natl. Acad. Sci. 1985;82:213–216. [PMC free article: PMC397002] [PubMed: 2982144]
  38. Bach J.M., Hurtrel M., Chakrabarti L., Ganiere J.P., Montagnier L., Hurtrel B. Early stages of feline immunodeficiency virus infection in lymph nodes and spleen. AIDS. 1994;10:1731–1738. [PubMed: 7888233]
  39. Bacon L.D. Influence of the major histocompatibility complex on disease resistance and productivity. Poult. Sci. 1987;66:802–811. [PubMed: 3306645]
  40. Bacon L.D., Crittenden L.B., Whitter R.L., Fadly A.D., Motta J. B5 and B15 are associated with progressive Marek's disease, Rous sarcoma, and avian leukosis virus-induced tumors in inbred 15L4 chickens. Poult. Sci. 1981a;62:573–578. [PubMed: 6306630]
  41. Bacon L.D., Fredrickson T.N., Gilmore D.G., Fadly A.M., Crittenden L.B. Tests of association of lymphocyte alloantigen genotypes with resistance to viral oncogenesis in chickens. 2. Rous sarcoma and lymphoid leukosis in progeny derived from 63 × 151 and 100 × 63 crosses. Poult. Sci. 1985;64:39–47. [PubMed: 2983298]
  42. Bacon L.D., Witter R.L., Crittenden L.B., Fadly A., Motta J. B haplotype influence on Marek's disease, Rous sarcoma, and lymphoid leukosis virus-induced tumors in chickens. Poult. Sci. 1981b;60:1132–1139. [PubMed: 6267578]
  43. Bai W., Arlinghaus R.B., Singh B. Association of v-Mos with soluble vimentin in vitro and in transformed cells. Oncogene. 1993;8:2207–2212. [PubMed: 8336943]
  44. Baichwal V.R., Tjian R. Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain δ: Differences between v- and c-Jun. Cell. 1990;63:815–825. [PubMed: 2121368]
  45. Balduzzi P.C., Notter M.F.D., Morgan H.R., Shibuya M. Some biological properties of two new avian sarcoma viruses. J. Virol. 1981;40:268–275. [PMC free article: PMC256616] [PubMed: 6270379]
  46. Ballard D.W., Dixon E.P., Peffer N.J., Bogerd H., Doerre S., Stein B., Greene W.C. The 65-kDa subunit of human NF-κB functions as a potent transcriptional activator and a target for v-Rel-mediated repression. Proc. Natl. Acad. Sci. 1992;89:1875–1879. [PMC free article: PMC48556] [PubMed: 1542686]
  47. Ballard D.W., Walker W.H., Doerre S., Sista P., Molitor J.A., Dixon E.P., Peffer N.J., Hannink M., Greene W.C. The v-rel oncogene encodes a κB enhancer binding protein that inhibits NF-κB function. Cell. 1990;63:803–814. [PubMed: 2225078]
  48. Bamford R.N., Battiata A.P., Burton J.D., Sharma H., Waldmann T.A. Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotropic virus type I region/IL-15 fusion message that lacks many upstream AUGs that normally attenuate IL-15 mRNA translation. Proc. Natl. Acad. Sci. 1996;93:2897–2902. [PMC free article: PMC39731] [PubMed: 8610139]
  49. Bandecchi P., Matteucci D., Baldinotti F., Guidi G., Tozzini F., Bendinelli M. Prevalence of feline immunodeficiency virus and other retroviral infections in sick cats in Italy. Vet. Immunol. Immunopathol. 1992;31:337–345. [PubMed: 1317073]
  50. Barbacid M. Ras genes. Annu. Rev. Biochem. 1987;56:779–828. [PubMed: 3304147]
  51. Barker C.S., Bear S.E., Keler T., Copeland N.G., Gilbert D.J., Jenkins N.A., Yeung R.S., Tsichlis P.N. Activation of the prolactin receptor gene by promoter insertion in a Moloney murine leukemia virus-induced rat thymoma. J. Virol. 1992;66:6763–6768. [PMC free article: PMC240173] [PubMed: 1404614]
  52. Barlough J.E., Ackerly C.D., George J.W., Levy N., Aceveda R., Moore P.F., Rideout B.A., Cooper M.D., Pedersen N.C. Acquired immune dysfunction in cats with experimentally induced feline immunodeficiency virus infection: Comparison of short-term and long term infections. J. Acquired Immune Defic. Syndr. 1991;4:219–227. [PubMed: 1671410]
  53. Barr M.C., Calle P.P., Roelke M.E., Scott F.W. Feline immunodeficiency virus infection in nondomestic felids. J. Zoo Wildl. Med. 1989;20:265–272.
  54. Barsky S.H., Cameron R., Ossan K.E., Tomita D., Holmes E.C. Rising incidence of bronchioalveolar lung-carcinoma and unique clinicopathological features. Cancer. 1994;73:1163–1170. [PubMed: 8313318]
  55. Barth C.F., Humphries E.H. A nonimmunosuppressive helper virus allows high efficiency induction of B-cell lymphomas by reticuloendotheliosis virus strain T. J. Exp. Med. 1988;167:89–108. [PMC free article: PMC2188818] [PubMed: 2826639]
  56. Bartholomew C., Ihle J.N. Retroviral insertions 90 kilobases proximal to the Evi1 myeloid transforming gene activate transcription from the normal promoter. Mol. Cell. Biol. 1991;11:1820–1828. [PMC free article: PMC359852] [PubMed: 1848663]
  57. Bartholomew C., Morishita K., Askew D., Buchberg A., Jenkins N.A., Copeland N.G., Ihle J.N. Retroviral insertions in the CB-1/Fim3 common site of integration activate expression of the Evi1 gene. Oncogene. 1989;4:529–534. [PubMed: 2542863]
  58. Bassin R.H., Tuttle N., Fischinger P.J. Rapid cell culture assay technique for murine leukemia viruses. Nature. 1971;229:564–566. [PubMed: 4925356]
  59. Bassin R.H., Ruscetti S., Ali I., Haapala D.K., Rein A. Normal DBA/2 mouse cells synthesize a glycoprotein which interferes with MCF virus infection. Virology. 1982;123:139–151. [PubMed: 6959413]
  60. Baszler T.V., Zachary J.F. Murine retroviral-induced spongiform neuronal degeneration parallels resident microglial cell infection. Lab. Invest. 1990;63:612–623. [PubMed: 2172651]
  61. Baszler T.V., Zachary J.F. Murine retroviral neurovirulence correlates with an enhanced ability of virus to infect selectively, replicate in, and activate resident microglial cells. Am. J. Pathol. 1991;138:655–671. [PMC free article: PMC1886285] [PubMed: 2000941]
  62. Battini J.L., Heard J.M., Danos O. Receptor choice determinants in the envelope glycoproteins of amphotropic, xenotropic and polytropic murine leukemia viruses. J. Virol. 1992;66:1468–1475. [PMC free article: PMC240871] [PubMed: 1310758]
  63. Baumbach W.R., Colston E.M., Cole M.D. Integration of the BALB/c ecotropic provirus into the colony-stimulating factor-1 growth factor locus in a myc retrovirus-induced murine monocyte tumor. J. Virol. 1988;62:3151–3155. [PMC free article: PMC253432] [PubMed: 3261346]
  64. Baxter E.W., Blyth K., Donehower L.A., Cameron E.R., Onions D.E., Neil J.C. Moloney murine leukemia virus-induced lymphomas in p53-deficient mice: Overlapping pathways in tumor development? J. Virol. 1996;70:2095–2100. [PMC free article: PMC190045] [PubMed: 8642629]
  65. Bear S.E., Bellacosa A., Lazo P.A., Jenkins N.A., Copeland N.G., Hanson C., Levan G., Tsichlis P.N. Provirus insertion in Tpl-1, an Ets-1-related oncogene, is associated with tumor progression in Moloney murine leukemia virus-induced rat thymic lymphomas. Proc. Natl. Acad. Sci. 1989;86:7495–7499. [PMC free article: PMC298091] [PubMed: 2552446]
  66. Bechade C., Dambrine G., David-Pfeuty T., Esnault E., Calothy G. Transformed and tumorigenic phenotypes induced by avian retroviruses containing the v-mil oncogene. J. Virol. 1988;62:1211–1218. [PMC free article: PMC253129] [PubMed: 3346945]
  67. Beebe A.M., Dua M., Faith T.G., Moore P.F., Pedersen N.C., Dandekar S. Primary stage of feline immunodeficiency virus infection: Viral dissemination and cellular targets. J. Virol. 1994a;68:3080–3091. [PMC free article: PMC236798] [PubMed: 8151773]
  68. Beebe A.M., Faith T.F., Sparger E.E., Torten M., Pedersen N.C., Dandekar S. Evaluation of in vivo and in vitro interactions of feline immunodeficiency virus and feline leukemia virus. AIDS. 1994b;8:873–878. [PubMed: 7946095]
  69. Begg A.M. A filterable endothelioma of the fowl. Lancet. 1927;II:912–915.
  70. Behringer R.R., Dewey M.J. Cellular site and mode of FV-2 action. Cell. 1985;40:441–447. [PubMed: 3855388]
  71. Bejcek B.E., Li D.Y., Deuel T.F. Transformation by v-sis locus by an internal autoactivation mechanism. Science. 1989;245:1496–1499. [PubMed: 2551043]
  72. Bellacosa A., Datta K., Bear S.E., Patriotis C., Lazo P.A., Copeland N.G., Jenkins N.A., Tsichlis P.N. Effects of provirus integration in the Tpl1/Ets1 locus in Moloney murine leukemia virus-induced rat T-cell lymphomas: Levels of expression, polyadenylation, transcriptional initiation, and differential splicing of the Ets-1 mRNA. J. Virol. 1994;68:2320–2330. [PMC free article: PMC236708] [PubMed: 8139017]
  73. Belli B., Wolff L., Nazarov V., Fan H. Proviral activation of the c-myb proto-oncogene is detectable in preleukemic mice infected neonatally with Moloney murine leukemia virus but not in resulting end stage T lymphomas. J. Virol. 1995;69:5138–5141. [PMC free article: PMC189334] [PubMed: 7609084]
  74. Ben-David Y., Bernstein A. Friend virus-induced erythroleukemia and the multistage nature of cancer. Cell. 1991;66:831–834. [PubMed: 1889087]
  75. Ben-David Y., Giddens E.B., Bernstein A. Identification and mapping of a common proviral integration site Fli1 in erythroleukemia cells induced by Friend murine leukemia virus. Proc. Natl. Acad. Sci. 1990a;87:1332–1336. [PMC free article: PMC53469] [PubMed: 2304901]
  76. Ben-David Y., Giddens E.B., Letwin K., Bernstein A. Erythroleukemia induction by Friend murine leukemia virus: Insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. Genes Dev. 1991;5:908–918. [PubMed: 2044959]
  77. Ben-David Y., Lavigueur A., Cheong G.Y., Bernstein A. Insertional inactivation of the p53 gene during Friend leukemia: A new strategy for identifying tumor suppressor genes. New Biol. 1990b;2:1015–1023. [PubMed: 2101628]
  78. Ben-David Y., Prideaux V.R., Chow V., Benchimol S., Bernstein A. Inactivation of the p53 oncogene by internal deletion or retroviral integration in erythroleukemic cell lines induced by Friend leukemia virus. Oncogene. 1988;3:179–185. [PubMed: 2842714]
  79. Ben-David Y., Bani M.R., Chabot B., De Koven A., Bernstein A. Retroviral insertions downstream of the heterogeneous nuclear ribonucleoprotein A1 gene in erythroleukemia cells: Evidence that A1 is not essential for cell growth. Mol. Cell. Biol. 1992;12:4449–4455. [PMC free article: PMC360369] [PubMed: 1406633]
  80. Bendinelli M., Matteucci D., Friedman H. Retrovirus-induced acquired immunodeficiencies. Adv. Cancer Res. 1985;45:125–181. [PubMed: 3004120]
  81. Bennett M., Steeves R.A., Cudowicz G., Mirand E.A., Russell L.B. Mutant SL alleles of mice affect susceptibility to Friend spleen focus-forming virus. Science. 1968;162:564–565. [PubMed: 4884354]
  82. Berberich S., Cole M.D. Casein kinase II inhibits the DNA-binding activity of Max homodimers but not Myc/Max heterodimers. Genes Dev. 1992;6:166–176. [PubMed: 1737614]
  83. Bergeron D., Poliquin L., Kozak C.A., Rassart E. Identification of a common viral integration region in Cas-Br-E murine leukemia virus-induced non-T-, non-B-cell lymphomas. J. Virol. 1991;65:7–15. [PMC free article: PMC240483] [PubMed: 1845910]
  84. Bergeron D., Houde J., Poliquin L., Barbeau B., Rassart E. Expression and DNA rearrangement of proto-oncogenes in Cas-Br-E-induced non-T, non-B leukemias. Leukemia. 1993;7:954–962. [PubMed: 8391616]
  85. Bergeron D., Poliquin L., Houde J., Barbeau B., Rassart E. Analysis of proviruses integrated in Fli-1 and Evi-1 regions in Cas-Br-E MuLV-induced non-T-, non-B-cell leukemias. Virology. 1992;191:661–669. [PubMed: 1448920]
  86. Bergold P.J., Wang J.Y.J., Littau V., Johnson E., Hardy W.D., Besmer P. Structure and origin of the HZ1-feline sarcoma virus (HZ2-FeSV). J. Virol. 1987;58:320–329. [PubMed: 2884777]
  87. Bernards A. Neurofibromatosis type 1 and Ras-mediated signaling: Filling in the Gaps. Biochim. Biophys. Acta. 1995;1242:43–59. [PubMed: 7626654]
  88. Besmer P., Snyder H.W. Jr., Murphy J.E., Hardy W.D. Jr. The Parodi-Irgens feline sarcoma virus and simian sarcoma virus have homologous oncogenes, but in different contexts of the viral genome. J. Virol. 1983a;46:606–613. [PMC free article: PMC255163] [PubMed: 6302323]
  89. Besmer P., Hardy W.D. Jr., Zuckerman E.E., Bergold P., Lederman L., Snyder H.W. Jr. The Hardy-Zuckerman 2-FeSV, a new feline retrovirus with oncogene homology to Abelson-MuLV. Nature. 1983b;303:825–827. [PubMed: 6306469]
  90. Besmer P., Lader E., George P., Bergold P.J., Qui F.-H., Zuckerman E.E., Hardy W.D. Jr. A new acute transforming feline retrovirus with fms homology specifies a C-terminally truncated version of the c-fms protein that is different from SM-feline sarcoma virus v-fms protein. J. Virol. 1986a;60:194–203. [PMC free article: PMC253917] [PubMed: 3018286]
  91. Besmer P., Murphy J.E., George P.C., Qui F.-H., Bergold P.J., Snyder H.W. Jr., Brodeur D., Zuckerman E.E., Hardy W.D. Jr. A new acute transforming feline retrovirus and relationship of its oncogene kit with the protein kinase gene family. Nature. 1986b;320:415–421. [PubMed: 3007997]
  92. Best S., Le Tissier P., Towers G., Stoye J.P. Positional cloning of the mouse retrovirus restriction gene Fv1. Nature. 1996;382:826–829. [PubMed: 8752279]
  93. Beug H., Graf T. Cooperation between viral oncogenes in avian erythroid and myeloid leukemia. Eur. J. Clin. Invest. 1989;19:491–502. [PubMed: 2559851]
  94. Beug H., Blundell P., Graf T. Reversibility of differentiation and proliferative capacity in avian myelomonocytic cells transformed by ts E26 leukemia virus. Genes Dev. 1987;1:277–286. [PubMed: 2824281]
  95. Beug H., Mullner E.W., Hayman M.J. Insights into erythroid differentiation obtained from studies on avian erythroblastosis virus. Curr. Opin. Cell Biol. 1994;6:816–824. [PubMed: 7880528]
  96. Beug H., Doderlein C., Freudenstein C., Graf T. Erythroblast cell lines transformed by temperature-sensitive mutants of avian erythroblastosis virus: A model system to study erythroid differentiation in vitro. J. Cell. Physiol. 1982a;1 (suppl.):195–207. [PubMed: 6279674]
  97. Beug H., Leutz A., Kahn P., Graf T. Ts mutants of E26 leukemia virus allow transformed myeloblasts, but not erythroblasts or fibroblasts to differentiate at the nonpermissive temperature. Cell. 1984;39:579–588. [PubMed: 6096011]
  98. Beug H., Palmieri S., Freudenstein C., Zentgraf H., Graf T. Hormone-dependent terminal differentiation in vitro of chicken erythroleukemia cells transformed by ts mutants of avian erythroblastosis virus. Cell. 1982b;28:579–588. [PubMed: 6954007]
  99. Beug H., Von Kirchbach A., Grieser S., Doederlein G., Graf T. Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation. Cell. 1979;18:375–390. [PubMed: 227607]
  100. Beug H., Hayman M.J., Graf T., Benedict S.H., Wallbank A.M., Vogt P.K. S13, a rapidly oncogenic replication-defective avian retrovirus. Virology. 1985;145:141–145. [PubMed: 2990096]
  101. Beutner U., Frankel W.N., Cote M.S., Coffin J.M., Huber B.T. Mls-1 is encoded by the long terminal repeat open reading frame of the mouse mammary tumor virus Mtv-7. Proc. Natl. Acad. Sci. 1992;89:5432–5436. [PMC free article: PMC49306] [PubMed: 1319061]
  102. Beutner U., Kraus E., Kitamura D., Rajewksy K., Huber B.T. B cells are essential for murine mammary tumor virus transmission, but not for presentation of endogenous superantigens. J. Exp. Med. 1994;179:1457–1466. [PMC free article: PMC2191484] [PubMed: 8163931]
  103. Bhagavati S., Ehrlich G., Kula R.W., Kwok S., Sninsky J., Udani V., Poiesz B.J. Detection of human T-cell lymphoma/leukemia virus type I DNA and antigen in spinal fluid and blood of patients with chronic progressive myelopathy. N. Engl. J. Med. 1988;318:1141–1147. [PubMed: 2896300]
  104. Bhigjee A.I., Wiley C.A., Wachsman W., Amenomori T., Pirie D., Bill P.L., Windsor I. HTLV-I-associated myelopathy: Clinicopathologic correlation with localization of provirus to spinal cord. Neurology. 1991;41:1990–1992. [PubMed: 1745362]
  105. Biedenkapp H., Borgmeyer U., Sippel A.E., Klempnauer K.-H. Viral myb oncogene encodes a sequence-specific DNA-binding activity. Nature. 1988;335:835–837. [PubMed: 3185713]
  106. Bilello J.A., Pitts O.M., Hoffman P.M. Characterization of a progressive neurodegenerative disease induced by a temperature-sensitive Moloney murine leukemia virus infection. J. Virol. 1986;59:234–241. [PMC free article: PMC253071] [PubMed: 3735486]
  107. Bishop J.M. The molecular genetics of cancer. Science. 1987;235:305–311. [PubMed: 3541204]
  108. Bishop J.M. Molecular themes in oncogenesis. Cell. 1991;64:235–248. [PubMed: 1988146]
  109. Birge R.B., Fajardo J.E., Reichman C., Shoelson S.E., Songyand Z., Cantley L.C., Hanafusa H. Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT-10 transformed fibroblasts. Mol. Cell. Biol. 1993;13:4648–4656. [PMC free article: PMC360091] [PubMed: 7687742]
  110. Blackwell T.K., Kretzner L., Blackwood E.M., Eisenman R.N., Weintraub H. Sequence-specific DNA binding by the c-Myc protein. Science. 1990;250:1149–1151. [PubMed: 2251503]
  111. Blackwood E.M., Eisenman R.N. Max: A helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science. 1991;251:1211–1217. [PubMed: 2006410]
  112. Blackwood E.M., Kretzner L., Eisenman R.N. Myc and Max function as a nucleoprotein complex. Curr. Opin. Genet. Dev. 1992a;2:227–235. [PubMed: 1638116]
  113. Blackwood E.M., Luscher B., Eisenman R.N. Myc and May associate in vivo. Genes Dev. 1992b;6:71–80. [PubMed: 1730411]
  114. Blair D.G., Oskarsson M., Wood T.G., McClements W.L., Fischinger P.J., Vande Woude G.F. Activation of the transforming potential of a normal cell sequence: A molecular model for oncogenesis. Science. 1981;212:941–943. [PubMed: 7233190]
  115. Blatt C.D., Aberdam C., Schwartz R., Sachs L. DNA rearrangement of a homeobox gene in myeloid leukaemic cells. EMBO J. 1988;7:4283–4290. [PMC free article: PMC455142] [PubMed: 2907477]
  116. Blattner W.A., Kalyanaraman V.S., Robert-Guroff M., Lister T.A., Galton D.A.G., Sarin P.S., Crawford M.H., Catovsky D., Greaves M., Gallo R.C. The human type C-retrovirus, HTLV, in blacks from the Caribbean region, and relationship to adult T-cell leukemia/lymphoma. Int. J. Cancer. 1982;30:257–264. [PubMed: 6290401]
  117. Blayney D.W., Jaffe E.S., Blattner W.A., Fisher R.I., Schecter G.P., Cossman J., Robert-Guroff M., Kalyanaraman V.S., Blattner W.A., Gallo R.C. The human T-cell leukemia lymphoma virus, lymphoma, lytic bone lesions and hypercalcemia. Ann. Intern. Med. 1983;98:144–151. [PubMed: 6600592]
  118. Blunt T., Finnie N.J., Taccioli G.E., Smith G.C., Demengeot J., Gottlieb T.M., Mizuta R., Varchese A.J., Alt F.W., Jeggo P.A., Jackson S.P. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell. 1995;80:813–823. [PubMed: 7889575]
  119. Boehmelt G., Walker A., Kaburn K., Mellitzer G., Beug H., Zenke M., Enrietto P.J. Hormone-regulated v-rel estrogen receptor fusion protein: Reversible induction of cell transformation and cellular gene expression. EMBO J. 1992;11:4641–4652. [PMC free article: PMC557040] [PubMed: 1425595]
  120. Boerkoel C.F., Kung H.J. Transcriptional interaction between retroviral long terminal repeats (LTRs): Mechanism of 5′ LTR suppression and 3′ LTR promoter activation of c-myc in avian B-cell lymphomas. J. Virol. 1992;66:4814–4823. [PMC free article: PMC241309] [PubMed: 1321271]
  121. Boguski M.S., McCormick F. Proteins regulating Ras and its relatives. Nature. 1993;366:643–653. [PubMed: 8259209]
  122. Bohmann D., Tjian R. Biochemical analysis of transcriptional activity by Jun: Differential activity of c- and v-Jun. Cell. 1989;59:709–717. [PubMed: 2510934]
  123. Boomer S., Gasper P., Whalen L.R., Overbaugh J. Isolation of a novel subgroup B feline leukemia virus from a cat infected with FeLV-A. Virology. 1994;204:805–810. [PubMed: 7941350]
  124. Boone L.R., Innes C.L., Glover P.L., Linney E. Development and characterization of an Fv-1-sensitive retrovirus-packaging system: Single-hit titration kinetics observed in restrictive cells. J. Virol. 1989;63:2592–2597. [PMC free article: PMC250735] [PubMed: 2542573]
  125. Boone L.R., Myer F.E., Yang D.M., Kiggans J.O., Koh C., Tennant R.W., Yang W.K. Reversal of Fv-1 host range by in vitro restriction endonuclease fragment exchange between molecular clones of N-tropic and B-tropic murine leukemia virus genomes. J. Virol. 1983;48:110–119. [PMC free article: PMC255327] [PubMed: 6310140]
  126. Boral A.L., Okenquist S.A., Lenz J. Identification of the SL3-3 virus enhancer core as a T-lymphoma cell-specific element. J. Virol. 1989;63:76–84. [PMC free article: PMC247659] [PubMed: 2535754]
  127. Bordereaux D., Fichelson S., Sola B., Tambourin P.E., Gisselbrecht S. Frequent involvement of the fim-3 region in Friend murine leukemia virus-induced mouse myeloblastic leukemias. J. Virol. 1987;61:4043–4045. [PMC free article: PMC256030] [PubMed: 2824835]
  128. Bos J.L. Ras oncogenes in human cancer: A review. Cancer Res. 1989;49:4682–4689. [PubMed: 2547513]
  129. Bos T.J., Monteclaro F.S., Mitsonubo F., Ball A.R. Jr., Change C.H., Nishimura T., Vogt P.K. Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences. Genes Dev. 1990;4:1677–1687. [PubMed: 2123464]
  130. Bosma M.J., Carroll A.M. The SCID mouse mutant: Definition, characterization, and potential uses. Annu. Rev. Immunol. 1991;9:323–350. [PubMed: 1910681]
  131. Boss M.A., Dreyfuss G., Baltimore D. Localization of the Abelson murine leukemia virus protein in a detergent-insoluble subcellular matrix: Architecture of the protein. J. Virol. 1981;40:471–481. [PMC free article: PMC256649] [PubMed: 6172595]
  132. Bowser P.R., Wooster G.A. Regression of dermal sarcomas in adult walleyes. J. Aquat. Anim. Health. 1991;3:147–150.
  133. Bowser P.R., Wolfe M.J., Formey J.L., Wooster G.A. Seasonal prevalence of skin tumors from walleye (Stizotedion vitreum) from Oneida Lake, New York. J. Wildl. Dis. 1988;24:292–298. [PubMed: 3373634]
  134. Brandt-Carlson C., Butel J.S. Detection and characterization of a glycoprotein encoded by the mouse mammary tumor virus long terminal repeat gene. J. Virol. 1991;65:6051–6060. [PMC free article: PMC250273] [PubMed: 1656086]
  135. Braun M.J., Clements J.E., Gonda M.A. The visna virus genome: Evidence for a hypervariable site in the env gene and sequence homology among lentivirus envelope proteins. J. Virol. 1987;61:4046–4054. [PMC free article: PMC256031] [PubMed: 2824836]
  136. Breuer M.L., Cuypers H.T., Berns A. Evidence for the involvement of pim-2, a new common proviral insertion site, in progression of lymphomas. EMBO J. 1989;8:743–748. [PMC free article: PMC400870] [PubMed: 2721500]
  137. Brightman B.K., Davis B.R., Fan H. Preleukemic hematopoietic hyperplasia induced by Moloney murine leukemia virus is an indirect consequence of viral infection. J. Virol. 1990;64:4582–4584. [PMC free article: PMC247933] [PubMed: 2200891]
  138. Brightman B.K., X. Li Q., Trepp D.J., Fan H. Differential disease restriction of Moloney and Friend murine leukemia viruses by the mouse Rmcf gene is governed by the viral long terminal repeat. J. Exp. Med. 1991;174:389–396. [PMC free article: PMC2118917] [PubMed: 1856627]
  139. Brodie S.J., Marcom K.A., Pearson L.D., Anderson B.C., De la Concha-Bermejillo A., Ellis J.A., DeMartini J.C. Effects of virus load in the pathogenesis of lentivirus-induced lymphoid interstitial pneumonia. J. Infect. Dis. 1992;166:531–541. [PubMed: 1323619]
  140. Brojatsch J., Kristal B.S., Viglianti G.A., Khiroya R., Hoover E.A., Mullins J.I. Feline leukemia virus subgroups C phenotype evolves through distinct alterations near the N terminus of the envelope surface glycoprotein. Proc. Natl. Acad. Sci. 1992;89:8457–8461. [PMC free article: PMC49939] [PubMed: 1326757]
  141. Brown D., Blais W.B., Robinson H. Long terminal repeat sequences influence the pathogenic potential of recombinants between Rous-associated virus types 0 and 1. J. Virol. 1988;62:3431–3437. [PMC free article: PMC253467] [PubMed: 2841495]
  142. Brown R.S., Wolke R.E., Saila S.B., Brown C.W. Prevalence of neoplasia in 10 New England populations of the soft-shell clam (Mya arenaria). Ann. N.Y. Acad. Sci. 1978;298:522–534. [PubMed: 280191]
  143. Brown W.C., Bissey L., Logan K.S., Pedersen N.C., Elder J.H., Collisson E.W. Feline immunodeficiency virus infects both CD4+ and CD8+ T lymphocytes. J. Virol. 1991;65:3359–3364. [PMC free article: PMC240997] [PubMed: 1709703]
  144. Brunner D., Pedersen N.C. Infection of peritoneal macrophages in vitro and in vivo with feline immunodeficiency virus. J. Virol. 1989;63:5483–5488. [PMC free article: PMC251221] [PubMed: 2479773]
  145. Buchberg A.M., Bedigian H.G., Jenkins N.A., Copeland N.G. Evi-2, a common integration site involved in murine myeloid leukemogenesis. Mol. Cell. Biol. 1990;10:4658–4666. [PMC free article: PMC361055] [PubMed: 2167436]
  146. Buckler A.J., Chang D.D., Graw S.L., Brook J.D., Haber D.A., Sharp P.A., Housman D.E. Exon amplification: A strategy to isolate mammalian genes based on RNA splicing. Proc. Natl. Acad. Sci. 1991;88:4005–4009. [PMC free article: PMC51582] [PubMed: 1850845]
  147. Buday L., Downward J. Epidermal growth factor regulates p21 ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor. Cell. 1993;73:611–620. [PubMed: 8490966]
  148. Buller R.S., Ahmed A., Portis J.L. Identification of two forms of an endogenous murine retroviral env gene linked to the Rmcf locus. J. Virol. 1987;61:29–34. [PMC free article: PMC255194] [PubMed: 3023705]
  149. Buller R.S., Sitbon M., Portis J.L. The endogenous mink cell focus-forming (MCF) gp70 linked to the Rmcf gene restricts MHC virus replication in vivo and provides partial resistance to erythroleukemia induced by Friend murine leukemia virus. J. Exp. Med. 1988;167:1535–1546. [PMC free article: PMC2188947] [PubMed: 2835418]
  150. Buller R.S., Van Zant G., Eldridge P.W., Portis J.L. A population of murine hematopoietic progenitors expresses an endogenous retroviral gp70 linked to the Rmcf gene and associated with resistance to erythroleukemia. J. Exp. Med. 1989;169:865–880. [PMC free article: PMC2189291] [PubMed: 2926325]
  151. Buller R.S., Wehrly K., Portis J.L., Chesebro B. Host genes conferring resistance to a central nervous system disease induced by a polytropic recombinant Friend murine retrovirus. J. Virol. 1990;64:493–498. [PMC free article: PMC249136] [PubMed: 2153219]
  152. Bundy L.M., Ru M., Zheng B., Cheng L., K. Pattengale P., Portis J.L., Fan H. Biological characterization and molecular cloning of murine C-type retroviruses for the TSZ complex from mainland China. Virology. 1995;212:367–382. [PubMed: 7571406]
  153. Bunn P.A. Jr., Schechter G.P., Jaffe E., Blayer D., Young R.C., Matthews M.J., Blattner W.A., Broder S., Guroff M., Gallo R.C. Clinical course of retrovirus-associated adult T-cell lymphoma in the United States. N. Engl. J. Med. 1983;309:257–264. [PubMed: 6602943]
  154. Burny A., Cleuter Y., Kettmann R., Mammerickx M., Marbaix G., Portelle D., Van den Broeke A., Willems L., Thomas R. Bovine leukemia: Facts and hypotheses derived from the study of an infectious cancer. Adv. Vet. Sci. Comp. Med. 1988;32:1652–1655. [PubMed: 2847501]
  155. Burns D.P.W., Desrosiers R.C. Envelope sequence variation and primate lentivirus persistence. Curr. Top. Microbiol. Immunol. 1994;188:175–219. [PubMed: 7523031]
  156. Callanan J.J., Thompson H.T., Toth S.J., O'Neill B., Lawrence C.L., Willert B., Jarrett O. Clinical and pathological findings in feline immunodeficiency virus experimental infection. Vet. Immunol. Immunopathol. 1992;35:3–13. [PMC free article: PMC7119604] [PubMed: 1337400]
  157. Canman C.E., Kastan M.B. Induction of apoptosis by tumor suppressor genes and oncogenes. Adv. Cancer Biol. 1995;6:17–25. [PubMed: 7548837]
  158. Cann A.J., Chen I.S.Y. 1996Human T-cell leukemia virus type I and II In Fields virology (ed. B.N. Fields et al.), pp. 1849–1880. Lippincott-Raven, New York.
  159. Cann A.J., Rosenblatt J.D., Wachsman W., Shah. N.P., Chen I.S.Y. Identification of the gene responsible for human T-cell leukemia virus transcriptional regulation. Nature. 1985;318:571–574. [PubMed: 2999613]
  160. Cappell M.S., Chow J. HTLV-I-associated lymphoma involving the entire alimentary tract and presenting with an acquired immune deficiency. Am. J. Med. 1987;82:649–654. [PubMed: 3030102]
  161. Carr J.G., Campbell J.G. Three new virus-induced sarcomata. Br. J. Cancer. 1958;12:631–635. [PMC free article: PMC2073950] [PubMed: 13628893]
  162. Carter T.H., Kung H.J. Tissue-specific transformation by oncogenic mutants of epidermal growth factor receptor. Crit. Rev. Oncog. 1994;5:389–428. [PubMed: 7711115]
  163. Cartwright C.A., Eckhart W., Simon S., Kaplan P.L. Cell transformation by pp60c-src mutated in the carboxyl-terminal regulatory domain. Cell. 1987;49:83–91. [PubMed: 3103927]
  164. Casadevall N., LaCombe C., Muller O., Gisselbrecht S., Mayeux P. Multimeric structure of the membrane erythropoietin receptor of murine erythroleukemia cells (Friend cells). Crosslinking of erythropoietin with the spleen focus-forming virus envelope protein. J. Biol. Chem. 1991;266:16015–16020. [PubMed: 1651930]
  165. Catovsky D., Rose M., Goolden A.W.G., White J.M., Bourikas G., Brownell A.I., Blattner W.A., Greaves M.F., Gaulton D.A.G., McCLusky D.R., Lampert I., Ireland R., Bridges J.M., Gallo R.C. Adult T-cell lymphoma-leukemia in blacks from the West Indies. Lancet. 1982;I:639–647. [PubMed: 6121963]
  166. Cavalieri F., Ruscio T., Tinoco R., Benedict S., Davis C., Vogt P.K. Isolation of three new avian sarcoma viruses: ASV 9, ASV 17, and ASV 25. Virology. 1985;143:680–683. [PubMed: 2998035]
  167. Cawthon R.M., Anderson L.B., Buchberg A.M., Xu G., O'Connel P., Viskochil D., Weiss R.B., Wallace M.R., Marchuk D.A., Culver M., Stevens J., Jenkins N.A., Copeland N.G., Collins F.S., White R. cDNA sequences and genomic structure of EVI-2B, a gene lying within an intron of the neurofibromatosis type 1 gene. Genomics. 1991;9:446–460. [PubMed: 1903357]
  168. Cazenave P.-A., Marche P., Jouvin-Marche E., Voegtle D., Bonhomme F., Bandeira A., Coutinho A. Vβ17 gene polymorphisms in wild-derived mouse strains: Two amino acid substitutions in the Vβ17 region alter T cell specificity. Cell. 1990;63:717–728. [PubMed: 2225073]
  169. Celander D., Haseltine W.A. Tissue-specific transcription preference as a determinant of cell tropism and leukemogenic potential of murine retroviruses. Nature. 1984;312:159–162. [PubMed: 6095084]
  170. Cerny A.A., Hugin A.W., Holmes K.L., Morse H.C. III. CD4+ T cells in murine acquired immunodeficiency syndrome: Evidence for an intrinsic defect in the proliferative response to soluble antigen. Eur. J. Immunol. 1990a;20:1577–1581. [PubMed: 1974851]
  171. Cerny A.A., Hugin A.W., Hardy R.R., Hayakawa K., Zinkernagel R.M., Makino M., Morse H.C. III. B cells are required for induction of T cell abnormalities in a murine retrovirus-induced immunodeficiency syndrome. J. Exp. Med. 1990b;171:315–320. [PMC free article: PMC2187666] [PubMed: 1967300]
  172. Ceroni M., Piccardo P., Rodgers-Johnson P., Mora C., Asher D.M., Gajdusek D.C., Gibbs C.J. Jr. Intrathecal synthesis of IgG antibodies to HTLV-I supports an etiological role for HTLV-I in tropical spastic paraparesis. Ann. Neurol. 1988;23 (suppl.):S188–S191. [PubMed: 2894812]
  173. Chabot B., Stephenson D.A., Chapman V.M., Besmer P., Bernstein A. The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature. 1988;335:88–89. [PubMed: 2457811]
  174. Chang W., Hubbard S.C., Friedel C., Ruley H.E. Enrichment of insertional mutants following retrovirus gene trap selection. Virology. 1993;193:737–747. [PubMed: 8460482]
  175. Chatila T., Geha R.S. Signal transduction by microbial superantigens via MHC class II molecules. Immunol. Rev. 1993;131:43–59. [PubMed: 8387456]
  176. Chatis P.A., Holland C.A., Hartley J., Rowe W.P., Hopkins N. Role of the 3′ end of the genome in determining disease specificity of Friend and Moloney murine leukemia viruses. Proc. Natl. Acad. Sci. 1983;80:4408–4411. [PMC free article: PMC384047] [PubMed: 6308622]
  177. Chatis P.A., Holland C.A., Silver J.E., Fredrickson T.N., Hopkins N., Hartley J.W. A 3′ end fragment encompassing the transcriptional enhancers of nondefective Friend virus congers eythroleukemogenicity on Moloney leukemia virus. J. Virol. 1984;52:248–254. [PMC free article: PMC254512] [PubMed: 6090701]
  178. Chattopadhyay S.K., Morse H.C. III, Makino M., Ruscetti S.K., Hartley J.W. Defective virus is associated with induction of murine retrovirus-induced immunodeficiency syndrome. Proc. Natl. Acad. Sci. 1989;86:3862–3866. [PMC free article: PMC287241] [PubMed: 2542949]
  179. Chattopadhyay S.K., Sengupta D.N., Fredrickson T.N., Morse H.C. III, Hartley J.W. Characteristics and contributions of defective, ecotropic, and mink cell focus-inducing viruses involved in a retrovirus-induced immunodeficiency syndrome. J. Virol. 1991;65:4232–4241. [PMC free article: PMC248860] [PubMed: 1649328]
  180. Chattopadhyay S.K., Cloyd M.W., Linemayer D.L., Lander M.R., Rands E., Lowy D.R. Cellular origin and role of mink cell focus-forming viruses in murine thymic lymphomas. Nature. 1982;295:25–31. [PubMed: 6276750]
  181. Cheevers W.P., McGuire T.C. The lentiviruses: Maedi/visna, caprine arthritis-encephalitis, and equine infectious anemia. Adv. Virus Res. 1988;34:189–215. [PubMed: 2843016]
  182. Cheevers W.P., Knowles D.P. Jr., Norton L.K. Neutralization-resistant antigenic variants of caprine arthritis-encephalitis lentivirus associated with progressive arthritis. J. Infect. Dis. 1991;164:679–685. [PubMed: 1654355]
  183. Cheevers W.P., Knowles D.P., McGuire T.C., Cunningham D.R., Adams D.S., Gorham J.R. Chronic disease in goats orally infected with two isolates of the caprine arthritis-encephalitis lentivirus. Lab. Invest. 1988;58:510–517. [PubMed: 2835548]
  184. Chen C., Biegalke B.J., Eisenman R.N., Linial M. FH3, a v-myc avian retrovirus with limited transforming ability. J. Virol. 1989;63:5092–5100. [PMC free article: PMC251171] [PubMed: 2555545]
  185. Chen I.S.Y., Quan S.G., Golde D.W. Human T-cell leukemia virus type II transformed normal human lymphocytes. Proc. Natl. Acad. Sci. 1983;80:7006–7009. [PMC free article: PMC390115] [PubMed: 6316341]
  186. Chen I.S.Y., Slamon D.J., Rosenblatt J.D., Shah N.P., Quan S.G., Wachsman W. The x gene is essential for HTLV replication. Science. 1985;229:54–58. [PubMed: 2990037]
  187. Chen S.J., Holbrook N.J., Mitchell K.F., Vallone C.A., Green-gard J.S., Crabtree G.R., Lin Y. A viral long terminal repeat in the interleukin 2 gene of a cell line that constitutively produces interleukin 2. Proc. Natl. Acad. Sci. 1985;82:7284–7288. [PMC free article: PMC390834] [PubMed: 3877307]
  188. Chen Y.Y., Wang L.C., Huang M.S., Rosenberg N. An active v-abl protein tyrosine kinase blocks immunoglobulin light-chain gene rearrangement. Genes Dev. 1994;8:688–697. [PubMed: 7926759]
  189. Chesebro B., Wehrly K. Rfv-1 and Rfv-2, two H-2-associated genes that influence recovery from Friend leukemia virus-induced splenomegaly. J. Immunol. 1978;120:1081–1085. [PubMed: 641338]
  190. Chesebro B., Wehrly K. Identification of a non-H-2 gene (Rfv-3) influencing recovery from viremia and leukemia induced by Friend virus complex. Proc. Natl. Acad. Sci. 1979;76:425–429. [PMC free article: PMC382952] [PubMed: 284359]
  191. Chien Y.H., Lai M., Shih T.Y., Verma I.M., Scolnick E.M., Roy-Burman P., Davidson N. Heteroduplex analysis of the sequence relationship between the genomes of Kirsten and Harvey sarcoma viruses, their respective parental murine leukemia viruses and the rat endogenous 30S RNA. Virology. 1979;31:752–760. [PMC free article: PMC353503] [PubMed: 229250]
  192. Chirigos M.A., Scott D., Turner W., Perk K. Biological, pathological and physical characterization of a possible variant of a murine sarcoma virus (Moloney). Int. J. Cancer. 1968;3:223–237. [PubMed: 5649158]
  193. Cho B.C., Shaughnessy J.D. Jr., Largaespada D.A., Bedigian H.G., Buchberg A.M., Jenkins N.A., Copeland N.G. Frequent disruption of the NF1 gene by a novel murine AIDS virus-related provirus in BXH-2 murine myeloid lymphomas. J. Virol. 1995;69:7138–7146. [PMC free article: PMC189634] [PubMed: 7474134]
  194. Cho K.R., Fearon E.R. DCC: Linking tumor suppressor genes and altered cell surface interactions in cancer? Curr. Opin. Genet. Dev. 1995;5:72–78. [PubMed: 7749329]
  195. Choi Y., Kappler J.W., Marrack P. A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus. Nature. 1991;350:203–207. [PubMed: 1706480]
  196. Choi Y., Marrack P., Kappler J.W. Structural analysis of a mouse mammary tumor virus superantigen. J. Exp. Med. 1992;175:847–852. [PMC free article: PMC2119154] [PubMed: 1311018]
  197. Chosa T.N., Yamamoto Y., Tanaka Y., Koyangi Y., Hinuma Y. Infectivity dissociated from transforming activity in a human retrovirus adult T-cell leukemia virus. Gann. 1982;73:844–847. [PubMed: 6761227]
  198. Chou M.M., Fajardo J.E., Hanafusa H. The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels. Mol. Cell. Biol. 1992;12:5834–5842. [PMC free article: PMC360523] [PubMed: 1280326]
  199. Chow V., Ben-David Y., Bernstein A., Benchimol S., Mowat M. Multistage Friend erythroleukemia: Independent origin of tumor clones from normal or rearranged p53 cellular oncogenes. J. Virol. 1987;61:2777–2781. [PMC free article: PMC255786] [PubMed: 3302314]
  200. Chung H.H., Benson D.R., Schultz P.G. Probing the structure and mechanism of Ras protein with an expanded genetic code. Science. 1993;259:806–869. [PubMed: 8430333]
  201. Chung S.W., Wolff L., Ruscetti S. Sequences responsible for the altered erythropoietin responsiveness in spleen focus-forming virus strain SFFVP-infected cells are localized to a 678-base-pair region at the 3′ end of the envelope gene. J. Virol. 1987;61:1661–1664. [PMC free article: PMC254150] [PubMed: 3033293]
  202. Church D.M., Stotler C.J., Rutter J.L., Murrell J.R., Trofatter J.A., Buckler A.J. Isolation of genes from complex sources of mammalian genomic DNA using exon amplification. Nat. Genet. 1994;6:98–105. [PubMed: 8136842]
  203. Clark H.F., Anderson P.R., Lunger P.D. Propagation and characterization of a C-type virus from a rhabdomyosarcoma of a corn snake. J. Gen. Virol. 1979;43:673–683.
  204. Clausse N., Smith R., Calberg-Bacq C.M., Peters G., Dickson C. Mouse mammary-tumor virus activates Fgf-3/Int-2 less frequently in tumors from virgin than from parous mice. Int. J. Cancer. 1993a;55:157–163. [PubMed: 8393839]
  205. Clausse N., Baines D., Moore R., Brookes S., Dickson C., Peters G. Activation of both Wnt-1 and Fgf-3 by insertion of mouse mammary tumor virus downstream in the reverse orientation: A reappraisal of the enhancer insertion model. Virology. 1993b;194:157–165. [PubMed: 8386870]
  206. Clements J.E., D'Antonio N., Narayan O. Genomic changes associated with antigenic variation of visna virus. II. Common nucleotide sequence changes detected in variants from independent isolations. J. Mol. Biol. 1982;158:415–434. [PubMed: 6182297]
  207. Cloyd M.W., Hartley J.W., Rose W.P. Lymphogenicity of recombinant mink cell focus-inducing murine leukemia viruses. J. Exp. Med. 1980;151:31–40. [PMC free article: PMC2185805] [PubMed: 6244357]
  208. Clurman B.E., Hayward W.S. Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: Evidence for stage-specific events. Mol. Cell. Biol. 1989;9:2657–2664. [PMC free article: PMC362338] [PubMed: 2548084]
  209. Cockerell G.L., Jensen W.A., Rovnak J., Ennis W.H., Gonda M.A. Seroprevalence of bovine immunodeficiencylike virus and bovine leukemia virus in a dairy herd. Vet. Microbiol. 1992;31:109–116. [PubMed: 1320785]
  210. Cockerell G.L., Weiser M.G., Rovnak J., Wicks-Beard B., Roberts B., Post A., Chen I.S.Y., Lairmore M.D. Infectious transmission of human T-cell lymphotropic virus type II in rabbits. Blood. 1991;78:1532–1537. [PubMed: 1832059]
  211. Coffin J.M. Superantigens and endogenous retroviruses: A confluence of puzzles. Science. 1992;255:411–413. [PubMed: 1310360]
  212. Coffin J.M. 1996 Retroviridae: The viruses and their replication In Fields virology (ed. B.N. Fields et al.), pp. 1767–1847. Lippincott-Raven, New York.
  213. Coffin J.M., Varmus H.E., Bishop J.M., Essex M., Hardy W.D. Jr., Martin G.S., Rosenberg N.E., Scolnick E.M., Weinberg R.A., Vogt P.K. Proposal for naming host cell-derived inserts in retrovirus genomes. J. Virol. 1981;40:953–957. [PMC free article: PMC256709] [PubMed: 7321107]
  214. Coggins L., Norcross N.L., Nusbaum S.R. Diagnosis of equine infectious anemia by immunodiffusion test. Am. J. Vet. Res. 1972;33:11–18. [PubMed: 4333633]
  215. Cohen G.B., Ren R., Baltimore D. Modular binding domains in signal transduction proteins. Cell. 1995;80:237–248. [PubMed: 7834743]
  216. Cohen J.B., Unger T., Rechavi G., Canaani E., Givol D. Rearrangement of the oncogene c-mos in mouse myeloma NSI and hybridomas. Nature. 1983;306:797–799. [PubMed: 6656883]
  217. Coll J., Roghi M., De Taisne C., Dissous C., Gegonne A., Stehlin D. Molecular cloning of the avian acute transforming retrovirus MH2 reveals a novel cell-derived sequence (v-mil) in addition to the myc oncogene. EMBO J. 1983;2:2189–2194. [PMC free article: PMC555433] [PubMed: 16453485]
  218. Collart K.L., Aurigemma R., Smith R.E., Kawai S., Robinson H.L. Infrequent involvement of c-fos in avian leukosis virus-induced nephroblastoma. J. Virol. 1990;64:3541–3544. [PMC free article: PMC249628] [PubMed: 2161956]
  219. Collett M. S., Purchio A.F., L. Erikson R. Avian sarcoma virus-transforming protein pp60src shows protein tyrosine kinase activity specific for tyrosine. Nature. 1980;285:167–169. [PubMed: 6246443]
  220. Collins W.M., Briles W.E., Zsigray R.M., Dunlop W.R., Corbett A.C., Clark K.K., Marks J.L., McGrail T.P. The B locus (MHC) in the chicken: Association with the fate of RSV-induced tumors. Immunogenetics. 1977;5:333–343.
  221. Collins W.M., Dunlop W.R., Zsigray R.M., Briles R.W., Fite R.W. Metastasis of Rous sarcoma tumors in chickens in influenced by the major histocompatibility (B) complex and sex. Poult. Sci. 1986;65:1642–1648. [PubMed: 3022275]
  222. Collins W.M., Zervas N.P., Urban W.E. Jr., Briles W.E., Aeed P.A. Response of B complex haplotypes B22, B24, and B26, to Rous sarcomas. Poult. Sci. 1985;64:2017–2019. [PubMed: 2999742]
  223. Compere S.J., Baldacci P., Jaenisch R. Oncogenes in transgenic mice. Biochim. Biophys. Acta. 1988;948:129–149. [PubMed: 3052590]
  224. Cooper M.D., Payne L.N., Dent P.B., Burmester B.R., Good R.A. Pathogenesis of avian lymphoid leukosis. I. Histogenesis. J. Natl. Cancer Inst. 1968;41:373–389. [PubMed: 5671285]
  225. Copeland N.G., Gilbert D.J., Cho B.C., Donovan P.J., Jenkins N.A., Cosman D., Anderson D., Lyman S.D., Williams D.E. Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles. Cell. 1990;63:175–183. [PubMed: 1698554]
  226. Corcoran L.M., Adams J.M., Dunn A.R., Cory S. Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion. Cell. 1984;37:113–122. [PubMed: 6327047]
  227. Cordier G., Guiguen F., Cadore J.L., Cozon G., Jacquier M.F., Mornex J.F. Characterization of the lymphocytic alveolitis in visna-maedi virus-induced interstitial lung disease. Clin. Exp. Immunol. 1992;90:18–24. [PMC free article: PMC1554546] [PubMed: 1327591]
  228. Cork L.C., Hadlow W.J., Crawford T.B., Gorham J.R., Piper R.C. Infectious leukoencephalomyelitis of young goats. J. Infect. Dis. 1974;129:134–141. [PubMed: 4810939]
  229. Coso O.A., Chiariello M., Yu J.C., Teramoto H., Crespo P., Xu N., Miki T., Gutkind J.S. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell. 1995;81:1137–1146. [PubMed: 7600581]
  230. Courchamp F., Pontier D. Feline immunodeficiency virus: An epidemiological review. C.R. Acad. Sci. III Life Sci. 1994;317:1123–1134. [PubMed: 7697467]
  231. Crawford T.B., Adams D.S. Caprine arthritis-encephalitis: Clinical features and presence of antibody in selected goat populations. J. Am. Vet. Med. Assoc. 1981;178:713–719. [PubMed: 6259112]
  232. Crawford T.B., Adams D.S., Cheevers W.P., Cork L.C. Uremic arthritis in goats caused by a retrovirus. Science. 1980;207:997–999. [PubMed: 6153243]
  233. Crittenden L.B., Fadly A.M., Smith E.J. Effect of endogenous leukosis virus genes on response to infection with avian leukosis and reticuloendotheliosis virus. Avian Dis. 1982;26:279–294. [PubMed: 6285878]
  234. Crittenden L.B., Smith E.J., Fadly A.M. Influence of endogenous virus (ev) gene expression and strain of exogenous avian leukosis virus (ALV) on mortality and ALV infection and shedding in chickens. Avian Dis. 1984;28:1037–1056. [PubMed: 6098248]
  235. Cross S.L., Feinberg M.B., Wolf J.B., Holbrook N.J., Wong-Staal F., Leonard W.J. Regulation of the human interleukin-2 receptor alpha promoter: Activation of a nonfunctional promoter by the transactivator gene of HTLV-I. Cell. 1987;49:47–56. [PubMed: 3030566]
  236. Cruickshank E.K. A neuropathic syndrome of uncertain origin. West Indian Med. J. 1956;5:147–158. [PubMed: 13381082]
  237. Cullen B.R., Lomedico P.T., Ju G. Transcriptional interference in avian retroviruses—Implications for the promoter insertion model of leukaemogenesis. Nature. 1984;307:241–245. [PubMed: 6363938]
  238. Cunningham T.P., Montelaro R.C., Rushlow K.E. Lentivirus envelope sequences and proviral genomes are stabilized in Escherichia coli when cloned in low copy-number plasmid vectors. Gene. 1993;124:93–98. [PubMed: 8382658]
  239. Curran T., Verma I.M. FBR osteosarcoma virus. I. Molecular analysis and characterization of a 75,000-Da gag-fos fusion product. Virology. 1984;135:218–228. [PubMed: 6203214]
  240. Custer R.P., Bosma G.C., Bosma M.J. Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms. Am. J. Pathol. 1985;120:464–477. [PMC free article: PMC1887984] [PubMed: 2412448]
  241. Cutlip R.C., Lehmkuhl H.D., Sacks J.M., Weaver A.L. Seroprevalence of ovine progressive pneumonia virus in sheep in the United States as assessed by analyses of voluntary samples. Am. J. Vet. Res. 1992a;53:976–979. [PubMed: 1320816]
  242. Cutlip R.C., Lehmkuhl H.D., Sacks J.M., Weaver A.L. Prevalence of antibody to caprine arthritis-encephalitis virus in goats in the United States. J. Am. Vet. Med. Assoc. 1992b;200:802–805. [PubMed: 1314795]
  243. Cuypers H.T., Selten G.C., Zijlstra M., DeGoede R.E., Melief C.J., Berns A.J. Tumor progression in murine leukemia virus-induced T-cell lymphomas: Monitoring clonal selections with viral and cellular probes. J. Virol. 1986;60:230–241. [PMC free article: PMC253921] [PubMed: 3091854]
  244. Cuypers H.T., Selten G., Quint W., Zijilstra M., Maandag E.R., Boelens W., van Wezenbeek P., Melief C., Berns A. Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region. Cell. 1984;37:141–150. [PubMed: 6327049]
  245. Czub M., McAtee F.J., Portis J.L. Murine retrovirus-induced spongiform encephalomyelopathy: Host and viral factors which determine the length of the incubation period. J. Virol. 1992;66:3298–3305. [PMC free article: PMC241107] [PubMed: 1316449]
  246. Czub M., Czub S., McAtee F.J., Portis J.L. Age-dependent resistance to murine retrovirus-induced spongiform neurodegeneration results from central nervous system-specific restriction of virus replication. J. Virol. 1991;65:2539–2544. [PMC free article: PMC240610] [PubMed: 1850027]
  247. Czub M., Czub S., Rappold M., Mazgareanu S., Schwender S., Demuth M., Hein A., Dorries R. Murine leukemia virus-induced neurodegeneration of rats: Enhancement of neuropathogenicity correlates with enhanced viral tropism for macrophages, microglia and brain vascular cells. Virology. 1995;214:239–244. [PubMed: 8525622]
  248. Da Y., Shanks R.D., Stewart J.A., Lewin H.A. Milk and fat yields decline in bovine leukemia virus-infected Holstein cattle with persistent lymphocytosis. Proc. Natl. Acad. Sci. 1993;90:6538–6541. [PMC free article: PMC46967] [PubMed: 8341665]
  249. Daenke S., Nightingale S., Cruickshank J.K., Bangham C.R. Sequence variants of human T-cell lymphotropic virus type I from patients with tropical spastic paraparesis and adult T-cell leukemia do not distinguish neurological from leukemic isolates. J. Virol. 1990;64:1278–1282. [PMC free article: PMC249244] [PubMed: 2304144]
  250. Dai Z., Pendergast A.M. Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. Genes Dev. 1995;9:2569–2582. [PubMed: 7590236]
  251. Damm K., Thompson C.C., Evans R.M. Protein encoded by v-erbA functions as a thyroid hormone receptor antagonist. Nature. 1989;339:593–597. [PubMed: 2733791]
  252. Dandekar S., Rossitto P., Pickett S., Mockli L., Bradshaw H., Cardiff R., Gardner M. Molecular characterization of the Akrv-1 restriction gene: A defective endogenous retrovirus-borne gene identical to Fv-4r. J. Virol. 1987;61:308–314. [PMC free article: PMC253951] [PubMed: 3027362]
  253. Daniel M.D., King N.W., Letvin N.L., Hunt R.D., Sehgal P.K., Desrosiers R.C. A new type D retrovirus isolated from macaques with an immunodeficiency syndrome. Science. 1984;223:602–605. [PubMed: 6695172]
  254. Davis B.R., Linney E., Fan H. Suppression of leukaemia virus pathogenicity by polyoma virus enhancers. Nature. 1985;314:550–553. [PubMed: 2986005]
  255. Davis B.R., Brightman B.K., Chandy K.G., Fan H. Characterization of a preleukemic stage induced by Moloney murine leukemic virus: Evidence for two infection events during leukemogenesis. Proc. Natl. Acad. Sci. 1987;84:4875–4879. [PMC free article: PMC305208] [PubMed: 3474632]
  256. Davis B.R., Chandy K.G., Brightman B.K., Gupta S., Fan H. Effects of nonleukemogenic and wild-type Moloney murine leukemia virus on lymphoid cells in vivo identification of a preleukemic shift in thymocyte subpopulations. J. Virol. 1986;60:423–430. [PMC free article: PMC288909] [PubMed: 3490580]
  257. Dawson M., Done S.H., Venables C., Jenkins C.E. Maedi-visna and sheep pulmonary adenomatosis: A study of concurrent infection. Br. Vet. J. 1990;146:531–538. [PubMed: 2176908]
  258. Dean G.A., Groshek P.M., Mullins J.I., Hoover E.A. Hematopoietic target cells of anemongenic subgroup C versus nonanemogenic subgroup A feline leukemia virus. J. Virol. 1992;66:5561–5568. [PMC free article: PMC289115] [PubMed: 1323710]
  259. DeMartini J.C., Rosadio R.H., Lairmore M.D. The etiology and pathology of ovine pulmonary carcinoma (sheep pulmonary adenomatosis). Vet. Microbiol. 1988;17:219–236. [PubMed: 3055655]
  260. DeMartini J.C., Brodie S.J., De la Concha-Bermejillo A., Ellis J.A., Lairmore M.D. Pathogenesis of lymphoid interstitial pneumonia in natural and experimental ovine lentivirus infection. Clin. Infect. Dis. 1993;17 (suppl.):S236–S242. [PubMed: 8399922]
  261. Dent P., Jelinek T., Morrison D.K., Weber M.J., Sturgill T.W. Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases. Science. 1995;268:1902–1906. [PubMed: 7604263]
  262. Derijard B., Hibi M., Wu I.H., Barrett T., Su B., Deng T., Karin M., Davis R.J. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell. 1994;76:1025–1037. [PubMed: 8137421]
  263. Derse D., Mikovits J., Polianova M., Felber B.K., Ruscetti F. Virions released from cells transfected with a molecular clone of human T-cell leukemia virus type I give rise to primary and secondary infections of T cells. J. Virol. 1995;69:1907–1912. [PMC free article: PMC188805] [PubMed: 7853532]
  264. Desbois C., Aubert D., Legarand C., Pain B., Samarut J. A novel mechanism of action for v-ErbA: Abrogation of the inactivation of transcription factor AP-1 by retinoic acid and thyroid hormone receptors. Cell. 1991;67:731–740. [PubMed: 1682056]
  265. DesGroseillers L., Jolicoeur P. Physical mapping of the Fv-1 tropism host range determinant of BALB/c murine leukemia virus. J. Virol. 1983;48:685–696. [PMC free article: PMC255401] [PubMed: 6313967]
  266. DesGroseillers L., Jolicoeur P. Mapping the viral sequences conferring leukemogenicity and disease specificity in Moloney and amphotropic murine leukemia viruses. J. Virol. 1984a;52:448–456. [PMC free article: PMC254545] [PubMed: 6092670]
  267. DesGroseillers L., Jolicoeur P. The tandem direct repeats within the long terminal repeat of murine leukemia viruses are the primary determinant of their leukemogenic potential. J. Virol. 1984b;52:945–952. [PMC free article: PMC254618] [PubMed: 6092722]
  268. DesGroseillers L., Barrette M., Jolicoeur P. Physical mapping of the paralysis-inducing determinant of a wild mouse ecotropic neurotropic retrovirus. J. Virol. 1984a;52:356–363. [PMC free article: PMC254534] [PubMed: 6092665]
  269. DesGroseillers L., Rassart E., Jolicoeur P. Thymotropism of murine leukemia virus is conferred by its long terminal repeat. Proc. Natl. Acad. Sci. 1983;80:4203–4207. [PMC free article: PMC384005] [PubMed: 6308605]
  270. DesGrosiellers L., Villemur R., Jolicoeur P. The high leukemogenic potential of Gross passage A murine leukemia virus maps in the region of the genome corresponding to the long terminal repeat and to the 3′ end of env. J. Virol. 1984b;47:24–32. [PMC free article: PMC255191] [PubMed: 6306276]
  271. DesGroseillers L., Rassart E., Robitaille Y., Jolicoeur P. Retrovirus-induced spongiform encephalopathy: The 3′-end long terminal repeat-containing viral sequences influence the incidence of the disease and the specificity of the neurological syndrome. Proc. Natl. Acad. Sci. 1985;82:8818–8822. [PMC free article: PMC391529] [PubMed: 3866255]
  272. Desrosiers R.C. The simian immunodeficiency viruses. Annu. Rev. Immunol. 1990;8:557–578. [PubMed: 2188674]
  273. Desrosiers R.C., Letvin N.L. Animal models for acquired immunodeficiency syndrome. Rev. Infect. Dis. 1987;9:438–446. [PubMed: 3037674]
  274. Devare S.G., Reddy E.P., Robbins K.C., Anderson P.R., Tronick S.R., Aaronson S.A. Nucleotide sequence of the transforming gene of simian sarcoma virus. Proc. Natl. Acad. Sci. 1982;79:3179–3182. [PMC free article: PMC346378] [PubMed: 6285340]
  275. Dhar R., Ellis R.W., Shih T.Y., Oroszlan S., Shapiro B., Maizel J., Lowy D., Scolnick E. Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus. Science. 1982;217:934–936. [PubMed: 6287572]
  276. Dickson C., Smith R., Brookes S., Peters G. Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int2. Cell. 1984;37:529–536. [PubMed: 6327073]
  277. Dickson C., Smith R., Brookes S., Peters G. Proviral insertions within the int2 gene can generate multiple anomalous transcripts but leave the protein-coding domain intact. J. Virol. 1990;64:784–793. [PMC free article: PMC249173] [PubMed: 2153243]
  278. Diehl L.J., Mathiason-DuBard C.K., O'Neill L.L., Hoover E.A. Longitudinal assessment of feline immunodeficiency virus kinetics in plasma by use of quantitative competitive reverse transcriptase PCR. J. Virol. 1995;69:2328–2332. [PMC free article: PMC188904] [PubMed: 7533856]
  279. Diglio C.A., Ferrer J.F. Induction of syncytia by the bovine C-type leukemia virus. Cancer Res. 1976;36:1056–1067. [PubMed: 175949]
  280. Dillon N., Grosveld F. Transcriptional regulation of multigene loci: Multilevel control. Trends Genet. 1993;9:134–137. [PubMed: 8516848]
  281. Dini P.W., Elton J.T., Lipsick J.S. Mutations in the DNA-binding and transcriptional activation domains of v-Myb cooperate in transformation. J. Virol. 1995;69:2515–2524. [PMC free article: PMC188928] [PubMed: 7884901]
  282. Djilali S.A., Parodi L., Levy D., Cockerell G.L. Development of leukemia and lymphosarcoma induced by bovine leukemia virus in sheep: A hematopathological study. Leukemia. 1987;1:777–781. [PubMed: 2824938]
  283. Dolcetti R., Rizzo S., Viel A., Maestro R., De Re V., Feriotto G., Boiocchi M. N-myc activation by proviral insertion in MCF 247-induced murine T-cell lymphomas. Oncogene. 1989;4:1009–1014. [PubMed: 2548143]
  284. Domenget C., Leprince D., Pain B., Peyrol S., Li R.P., Stehelin D., Samarut J., Jurdic P. The various domains of v-myb and v-ets oncogenes of E26 retrovirus contribute differently, but cooperatively, in transformation of hematopoietic lineages. Oncogene. 1992;7:2231–2241. [PubMed: 1331935]
  285. Donahue P.R., Quakenbush S.L., Gallo M.V., DeNoronha C.M., Overbaugh J., Hoover E.A., Mullins J.I. Viral genetic determinants of T-cell killing and immunodeficiency disease induction by the feline leukemia virus FeLV-FAIDS. J. Virol. 1991;65:4461–4469. [PMC free article: PMC248886] [PubMed: 1649341]
  286. Donehower L.A., Godley L.A., Aldez C.M., Pyle R., P. Shi Y., Pinkel D., Gray J., Bradley A., Medina D., Varmus H.E. Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. Genes Dev. 1995;9:882–895. [PubMed: 7705663]
  287. Doolittle R.F., Hunkapiller M.W., Hood L.E., Devare S.G., Robbins K.C., Aaronson S.A., Antoniades H.N. Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor. Science. 1983;221:275–277. [PubMed: 6304883]
  288. Dorner A.J., Coffin J.M. Determinants for receptor interaction and cell killing on the avian retrovirus glycoprotein gp85. Cell. 1986;45:365–374. [PubMed: 3009025]
  289. Dornsife R.E., Gasper P.W., Mullins J.I., Hoover E.A. Induction of aplastic anemia by intra-bone marrow inoculation of a molecularly cloned feline retrovirus. Leuk. Res. 1989;13:745–755. [PubMed: 2552228]
  290. Dow S.W., Dreitz M.J., Hoover E.A. Feline immunodeficiency virus neurotropism: Evidence that astrocytes and microglia are the primary target cells. Vet. Immunol. Immunopathol. 1992;35:23–35. [PubMed: 1337399]
  291. Dow S.W., Poss M.L., Hoover E.A. Feline immunodeficiency virus: A neurotropic lentivirus. J. Acquired Immune Defic. Syndr. 1990;3:658–668. [PubMed: 2161920]
  292. Downward J., Yarden Y., Mayes E., Scrace G., Totty N., Stockwell P., Ullrich A., Schlessinger J., Waterfield M.D. Close similarity of epidermal growth factor receptor and v-erbB oncogene proteins sequences. Nature. 1984;307:521–527. [PubMed: 6320011]
  293. Doyon L., Simard C., Sekaly R.P., Jolicoeur P. Evidence that the MAIDS defective virus does not encode a superantigen. J. Virol. 1995;70:1–9. [PMC free article: PMC189780] [PubMed: 8523511]
  294. Dreyfus F., Sola B., Fichelson S., Varlet P., Charon M., Tambourin P., Wendling F., Gisselbrecht S. Rearrangements of the Pim-1, c-myc, and p53 genes in Friend helper virus-induced mouse erythroleukemias. Leukemia. 1990;4:590–594. [PubMed: 2143796]
  295. Dua N., Reubel G., Moore P.F., Higgins J., Pedersen N.C. An experimental study of primary feline immunodeficiency virus infection in cats and a historical comparison to acute simian and human immunodeficiency virus diseases. Vet. Immunol. Immunopathol. 1994;43:337–355. [PubMed: 7856070]
  296. Dube D.K., Sherman M.P., Saksena N.K., Bryz-Gornia V., Mendelson J., Love J., Arnold C.B., Spicer T., Dube S., Glaser J.B., Williams A.E., Nishimura M., Jacobsen S., Ferrer J.F., Del Pino N., Quiruelas S., Poiesz B.J. Genetic heterogeneity in human T-cell leukemia/lymphoma virus type II. J. Virol. 1993;67:1175–1184. [PMC free article: PMC237482] [PubMed: 8437209]
  297. Duhrsen U., Stahl J., Gough N.M. In vivo transformation of factor-dependent hemopoietic cells: Role of intracisternal A-particle transposition for growth factor gene activation. EMBO J. 1990;9:1087–1096. [PMC free article: PMC551783] [PubMed: 2108861]
  298. Durand D.B., Kamoun M., Norris C.A., Holbrook N.J., Green-gard J.S., Crabtree G.R., Kant J.A. Retroviral activation of interleukin 2 gene in a gibbon ape T cell lymphoma line. J. Exp. Med. 1986;164:1723–1734. [PMC free article: PMC2188461] [PubMed: 3021892]
  299. Durban E., Boettiger D. Differential effects of transforming avian RNA tumor viruses on avian macrophages. Proc. Natl. Acad. Sci. 1981;78:3600–3604. [PMC free article: PMC319618] [PubMed: 6267600]
  300. Durgam V.R., Tekmal R.R. The nature and expression of int5, a novel MMTV integration locus gene in carcinogen-induced mammary tumors. Cancer Lett. 1994;87:178–186. [PubMed: 7812938]
  301. Dutta S.K., Larson V.L., Sorenson D.K., Perman A., Weber A.F., Hammer R.F., Shope R.E. 1970Isolation of C-type virus particles from leukemic and lymphocytic cattle In Comparative leukemia research 1969 (ed. R.M. Dutcher), pp. 538–544. Karger, Basel.
  302. Eck B., Westermark B., Wasteson A., Heldin C.-H. Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor. Nature. 1982;295:419–420. [PubMed: 6173766]
  303. Egan S.E., Giddings B.W., Brooks M.W., Buday L., Sizeland A.M., Weinberg R.A. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature. 1993;363:45–51. [PubMed: 8479536]
  304. Ejima E., Rosenblatt J.D., Massari M., Quan E., Stephens D., Rosen C.A., Prager D. Cell type-specific transactivation of the parathyroid hormone-related protein gene promoter by the HTLV-I tax and HTLV-II tax proteins. Blood. 1993;81:1017–1024. [PubMed: 8427983]
  305. Elder J.H., Gautsch J.W., Jensen F.C., Lerner R.A., Hartley J.W., Rowe W.P. Biochemical evidence that MCF murine leukemia viruses are envelope (env) gene recombinants. Proc. Natl. Acad. Sci. 1977;74:4676–4680. [PMC free article: PMC432010] [PubMed: 200928]
  306. Ellerman V., Bang O. Experimentell leukamie bei huhnern. Zentralbl. Bakteriol. 1908;46:595–609.
  307. Ellis R.W., DeFeo D., Maryak J.M., Young H.A., Shih T.Y., Change E.H., Lowy D.R., Scolnick E.M. Dual evolutionary origin for the rat genomic sequences of Harvey murine sarcoma virus. J. Virol. 1980;36:408–420. [PMC free article: PMC353657] [PubMed: 6253666]
  308. Ellis T.M., Wilcox G.E., Robinson W.F. Antigenic variation of caprine arthritis-encephalitis virus during persistent infection of goats. J. Gen. Virol. 1987;68:3145–3152. [PubMed: 2826652]
  309. Elovaara I., Koenig S., Brewah A.Y., Woods R.M., Lehky T., Jacobson S. High human T cell lymphotropic virus type 1 (HTLV-1)-specific precursor cytotoxic T lymphocyte frequencies in patients with HTLV-1-associated neurological disease. J. Exp. Med. 1993;177:1567–1573. [PMC free article: PMC2191033] [PubMed: 8496677]
  310. Elson A., Deng C., Campos-Torres J., Donehower L.A., Leder P. The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice. Oncogene. 1995;11:181–190. [PubMed: 7624126]
  311. El-Torky M., El-Zeky F., Hall J.C. Significant changes in the distribution of histologic types of lung cancer: A review of 4928 cases. Cancer. 1990;65:2361–2367. [PubMed: 2161283]
  312. Engelbreth-Holm J., Rothe-Meyer A. On the connection between erythroblastosis (haemocytoblastosis), myelosis, and sarcoma in the chicken. Acta Pathol. Microbiol. Scand. 1935;12:352–365.
  313. Engelke U., Lipsick J.S. Transformation of myelomonocytic cells by the avian myeloblastosis virus is determined by the v-myb oncogene, not by the unique long terminal repeats of the virus. J. Virol. 1994;68:2752–2755. [PMC free article: PMC236755] [PubMed: 8139052]
  314. English R.V., Johnson C.M., Gebhard D.H., Tompkins M.B. In vivo lymphocyte tropism of feline immunodeficiency virus. J. Virol. 1993;67:5175–5186. [PMC free article: PMC237915] [PubMed: 7688819]
  315. Enrietto P.J., Payne L.N., Wyke J.A. Analysis of the pathogenicity of transformation defective partial deletion mutants of avian sarcoma virus: Characterization of recovered viruses which encode novel src specific proteins. Virology. 1983;127:397–411. [PubMed: 6306917]
  316. Escot C., Hogg E., Callahan R. Mammary tumorigenesis in feral Mus cervicolor popaeus. J. Virol. 1986;58:619–625. [PMC free article: PMC252952] [PubMed: 3009873]
  317. Evangelista A., Maroushek S., Minnigan H., Larson A., Retzel E., Haase A., Gonzalez-Dunia D., McFarlin D., Mingioli E., Jacobson S., Osame M., Sonda S. Nucleotide sequence analysis of a provirus derived from an individual with tropical spastic paraparesis. Microb. Pathog. 1990;8:259–278. [PubMed: 2200942]
  318. Eychene A., Bechade C., Marx M., Laugier D., Dezelee P., Calothy G. Molecular and biochemical properties of c-mil transducing retroviruses generated during passage of Rous-associated virus type 1 in chicken neuroretina cells. J. Virol. 1990;64:231–238. [PMC free article: PMC249095] [PubMed: 2152814]
  319. Fabian J.R., Morrison D.K., Daar I.O. Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes. J. Cell Biol. 1993;122:645–652. [PMC free article: PMC2119675] [PubMed: 8335690]
  320. Fajardo J.E., Birge R.B., Hanafusa H. A 31 amino-acid N-terminal extension regulates c-Crk binding to tyrosine-phosphorylated proteins. Mol. Cell. Biol. 1993;13:7295–7302. [PMC free article: PMC364800] [PubMed: 7504172]
  321. Famulari N. Murine leukemia viruses with recombinant env genes: A discussion of their role in leukemogenesis. Curr. Top. Microbiol. Immunol. 1983;103:75–108. [PubMed: 6303710]
  322. Fan H., Brightman B.K., Davis B.R., Li Q.X. 1991Leukemogenesis by Moloney murine leukemia virus In Viruses that affect the immune system (ed. H.Y. Fan et al.), pp. 155–174. American Society for Microbiology, Washington, D.C.
  323. Fan H., Chute H., Chao E., Pattengale P.K. Leukemogenicity of Moloney murine leukemia viruses carrying polyoma enhancer sequences in the long terminal repeat is dependent on the nature of the inserted polyoma sequences. Virology. 1988;166:58–65. [PubMed: 2842957]
  324. Farcet J.P., Lebargy F., Lavignac C., Gaulard P., Dautry A., Gazzolo L., Romeo P.H., Vainchenker W. Constitutive IL-2 expression in HTLV-I-infected leukaemic T cell lines. Clin. Exp. Immunol. 1991;4:415–421. [PMC free article: PMC1535429] [PubMed: 1710547]
  325. Felber B.K., Paskalis H., Kleinman-Ewing C., Wong-Staal F., Pavlakis G.N. The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats. Science. 1985;229:675–679. [PubMed: 2992082]
  326. Felder M.P., Eychene A., Barnier J.V., Calogeraki I., Calothy G., Marx M. Common mechanism of retrovirus activation and transduction of c-mil and c-Rmil in chicken neuroretina cells infected with Rous-associated virus type 1. J. Virol. 1991;65:3633–3640. [PMC free article: PMC241371] [PubMed: 1645786]
  327. Feller S.M., Knudsen B., Hanafusa H. c-Abl kinase regulates the protein binding activity of c-Crk. EMBO J. 1994;13:2341–2351. [PMC free article: PMC395099] [PubMed: 8194526]
  328. Ferro F., Kozak S., Hoatlin M., Kabat D. Cell surface site for mitogenic interaction of erythropoietin receptors with the membrane glycoprotein encoded by Friend erythroleukemia virus. J. Biol. Chem. 1993;268:5741–5747. [PubMed: 8449938]
  329. Feuer G., Lee W.T., Pattengale P.K., Fan H.Y. Specificity of disease induced by M-MuLV chimeric retroviruses containing v-myc or v-src is not determined by the LTR. Virology. 1993a;195:286–291. [PubMed: 8391185]
  330. Feuer G., Zack J.A., Harrington W.J. Jr., Valderama R., Rosenblatt J.D., Wachsman W., Baird S.M., Chen I.S.Y. Establishment of human T-cell leukemia virus type I T-cell lymphomas in severe combined immunodeficient mice. Blood. 1993b;82:722–731. [PubMed: 8338942]
  331. Filardo E.J., Lee M.F., Humphries E.H. Structural genes, not the LTRs are the primary determinants of reticuloendotheliosis virus A-induced runting and bursal atrophy. Virology. 1994;202:116–128. [PubMed: 8009826]
  332. Fine D., Schochetman G. Type D primate retroviruses: A review. Cancer Res. 1978;38:3123–3139. [PubMed: 80259]
  333. Finkel M.P., Biskis B.O., Jinkins P.B. Virus induction of osteosarcomas in mice. Science. 1966;151:698–701. [PubMed: 5218049]
  334. Finkel M.P., Reilly C.A. Jr., Biskis B.O. Viral etiology of bone cancer. Front. Radiat. Ther. Oncol. 1975;10:28–39.
  335. Finkel M.P., Reilly C.A. Jr., Biskis B.O., Greco I.L. 1973Bone tumor viruses In BoneCertain aspects of neoplasia (ed. C.H.G. Price and F.G.M. Ross), pp. 353–366. Butterworths, London.
  336. Firulli B.A., Anderson G.R., Stoler D.L., Estes S.D. Anoxia-inducible rat VL30 elements and their relationship to ras-containing sarcoma viruses. J. Virol. 1993;67:6857–6862. [PMC free article: PMC238132] [PubMed: 8411389]
  337. Fischinger P.J., Ihle J.N., Bolognesi D.P., Schafer W. A novel murine oncornavirus with dual eco- and xenotropic properties. Proc. Natl. Acad. Sci. 1975;71:346–351. [PMC free article: PMC388894] [PubMed: 1061100]
  338. Fitzpatrick E.A., Bryson J.S., Rhoads C., Kaplan A.M., Cohen D.A. T-deficient transmembrane signaling in CD4+ T cells of retroviral-induced immune-deficient mice. J. Immunol. 1992;148:3377–3384. [PubMed: 1350288]
  339. Fleming T.P., Matsui T., Molloy C.J., Robbins K.C., Aaronson S.A. Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors. Proc. Natl. Acad. Sci. 1989;86:8063–8067. [PMC free article: PMC298215] [PubMed: 2813378]
  340. Flubacher M.M., Bear S.E., Tsichlis P.N. Replacement of interleukin-2 (IL-2)-generated mitogenic signals by mink cell focus-forming (MCF) or xenotropic virus-induced IL-9-dependent autocrine loop: Implications for MCF virus-induced leukemogenesis. J. Virol. 1994;68:7709–7716. [PMC free article: PMC237232] [PubMed: 7966560]
  341. Forrest D., Onions D., Lees G., Neil J.C. Altered structure and expression of c-myc in feline T-cell tumours. Virology. 1987;158:194–205. [PubMed: 3033889]
  342. Fossum C., Burney A., Portelle D., Mammerickx M., Morein B. Detection of B and T cells with lectins or antibodies in healthy or bovine leukemia virus-infected cattle. Vet. Immunol. Immunopathol. 1988;18:269–278. [PubMed: 2839934]
  343. Foster R.G., Robinson H.L. Establishment of interference in osteoblasts by an osteopetrosis-inducing avian leukosis virus. Virology. 1994;205:376–378. [PubMed: 7975235]
  344. Foster R.G., Lian J.B., Stein G., Robinson H.L. Replication of an osteopetrosis-inducing avian leukosis virus in fibroblasts, osteoblasts and osteopetroitc bone. Virology. 1994;205:179–187. [PubMed: 7975214]
  345. Frampton J., Kozuzarides T., Doderlein G., Graf T., Weston K. Influence of the v-Myb transactivation domain on the oncoprotein's transformation specificity. EMBO J. 1993;12:1333–1341. [PMC free article: PMC413345] [PubMed: 8467793]
  346. Frampton J., McNagny K., Sieweke M., Philip A., Smith G., Graf T. v-Myb DNA binding is required to block thrombocytic differentiation of Myb-Ets-transformed multipotent hematopoietic progenitors. EMBO J. 1995;14:2866–2875. [PMC free article: PMC398405] [PubMed: 7540977]
  347. Franchini G., Wong-Staal F., Gallo R.C. Human T-cell leukemia virus (HTLV-I) transcripts in fresh and cultured cells of patients with adult T-cell leukemia. Proc. Natl. Acad. Sci. 1982;81:6207–6211. [PMC free article: PMC391889] [PubMed: 6091140]
  348. Francis-Floyd R., Bolon B., Fraser W., Reed P. Lip fibromas associated with retrovirus-like particles in angel fish. J. Am. Vet. Assoc. 1993;202:427–429. [PubMed: 8440638]
  349. Frankel W.N., Rudy C., Coffin J.M., Huber B.T. Linkage of Mls genes to endogenous mammary tumour viruses of inbred mice. Nature. 1991;349:526–528. [PubMed: 1846948]
  350. Frankel W.N., Stoye J.P., Taylor B.A., Coffin J.M. Genetic identification of endogenous polytropic proviruses by using recombinant inbred mice. J. Virol. 1989;63:3810–3821. [PMC free article: PMC250974] [PubMed: 2547997]
  351. Frankel W.N., Potter T.A., Rosenberg N., Lenz J., Rajan T.V. Retroviral insertional mutagenesis of a target allele in a heterozygous murine cell line. Proc. Natl. Acad. Sci. 1985;82:6600–6604. [PMC free article: PMC391257] [PubMed: 2995973]
  352. Franz T., Lohler J., Fusco A., Pragnell I., Nobis P., Padua R., Ostertag W. Transformation of mononuclear phagocytes in vivo and malignant histiocytosis caused by a novel murine spleen focus-forming virus. Nature. 1985;315:149–151. [PubMed: 3873013]
  353. Franz W.M., Berger P., Wang J.Y. Deletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potential. EMBO J. 1989;8:137–147. [PMC free article: PMC400782] [PubMed: 2496972]
  354. Fredrickson T.N., Purchase H.G., Burmester B.R. Transmission of virus from field cases of avian lymphomatosis. III. Variation in the oncogenic spectra of passaged virus isolates. Natl. Cancer Inst. Monogr. 1964;17:1–29.
  355. Fredrickson T.N., Langdon W.Y., Hoffman P.M., Hartley J.W., Morse H.C. III. Histologic and cell surface antigen studies of hematopoietic tumors induced by Cas-Br-M murine leukemia virus. J. Natl. Cancer Inst. 1984;72:447–454. [PubMed: 6319793]
  356. Fredrickson T.N., O'Neill R.R., Rutledge R.A., Theodore T.S., Martin M.A., Ruscetti S.K., Austin J.B., Hartley J.W. Biologic and molecular characterization of two newly isolated ras-containing murine leukemia viruses. J. Virol. 1987;61:2109–2119. [PMC free article: PMC254231] [PubMed: 3035212]
  357. Freed E., Symons M., MacDonald S.G., McCormick F., Ruggieri R. Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation. Science. 1994;265:1713–1716. [PubMed: 8085158]
  358. Friel J., Hughes D., Pragnell I., Stocking C., Laker C., Nowock J., Ostertag W., Padua R.A. The malignant histiocytosis sarcoma virus, a recombinant of Harvey murine sarcoma virus and Friend mink cell focus-forming virus, has acquired myeloid transformation specificity by alterations in the long terminal repeat. J. Virol. 1990;64:369–378. [PMC free article: PMC249111] [PubMed: 2152823]
  359. Friend C. Cell-free transmission in adult Swiss mice of a disease having the character of a leukemia. J. Exp. Med. 1957;105:307–318. [PMC free article: PMC2136697] [PubMed: 13416470]
  360. Frykberg L., Graf T., Vennstrom B. The transforming activity of the chicken c-myc gene can be potentiated by mutations. Oncogene. 1987;1:415–422. [PubMed: 3330784]
  361. Frykberg L., Palmieri S., Beug H., Graf T., Hayman M.J., Vennstrom B. Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes. Cell. 1983;32:53–68. [PubMed: 6297784]
  362. Frykberg L., Metz T., Brady G., Introna M., Beug H., Vennstrom B., Graf T. A point mutation in the DNA binding domain of the v-myb oncogene of E26 virus confers temperature sensitivity for transformation of myelomonocytic cells. Oncogene Res. 1988;3:313–322. [PubMed: 2852341]
  363. Fuerstenberg S., Leitner I., Chroeder C., Schwarz H., Vennstrom B., Beug H. Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype. EMBO J. 1992;11:3355–3365. [PMC free article: PMC556870] [PubMed: 1354613]
  364. Fujii M., Sassone-Corsi P., Verma I.M. c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I. Proc. Natl. Acad. Sci. 1988;85:8526–8530. [PMC free article: PMC282491] [PubMed: 2847164]
  365. Fujii M., Tsuchiya H., Chuhjo T., Akizawa T., Seiki M. Interaction of HTLV-I tax with p67 (SRF) causes aberrant induction of cellular immediate early genes through CarG boxes. Genes Dev. 1992;6:2066–2076. [PubMed: 1427072]
  366. Fujii M., Niki T., Mori T., Matsuda T., Matsui M., Nomura N., Seiki M. HTLV-I tax induces expression of various immediate early serum responsive genes. Oncogene. 1991;6:1023–1029. [PubMed: 1906155]
  367. Fujinami A., Inamoto K. Ueber Gerwultse bei japanishen Haushuhnern insbesondere uber einen transplantablen Tumor. Z. Krebsforsch. 1914;14:94–119.
  368. Fujisawa J., Seiki M., Kiyokawa T., Yoshida M. Functional activation of the long terminal repeat of human T-cell leukemia virus type I by a trans-acting factor. Proc. Natl. Acad. Sci. 1985;82:2277–2281. [PMC free article: PMC397540] [PubMed: 2986109]
  369. Fukuhara S., Hinuma Y., Gotoh Y.-I., Uchino H. Chromosome aberrations in T lymphocytes carrying adult T-cell leukemia-associated antigens (ATLA) from healthy adults. Blood. 1983;61:205–207. [PubMed: 6600212]
  370. Fulton R., Plumb M., Shield L., Neil J.C. Structural diversity and nuclear protein binding sites in the long terminal repeats of feline leukemia virus. J. Virol. 1990;64:1675–1682. [PMC free article: PMC249304] [PubMed: 2157050]
  371. Fung Y.K., Crittenden L.B., Kung H.J. Orientation and position of avian leukosis virus DNA relative to the cellular oncogene c-myc in B-lymphoma tumors of highly susceptible 15I5 X 7(2) chickens. J. Virol. 1982a;44:742–746. [PMC free article: PMC256323] [PubMed: 6292531]
  372. Fung Y.K., Crittenden L.B., Fadley A.M., Kung H.J. Tumor induction by direct injection of cloned v-src DNA into chickens. Proc. Natl. Acad. Sci. 1983a;80:353–357. [PMC free article: PMC393375] [PubMed: 6300833]
  373. Fung Y.K., Fadly A.M., Crittenden L.B., Kung H.J. On the mechanism of retrovirus-induced avian lymphoid leukosis: Deletion and integration of the proviruses. Proc. Natl. Acad. Sci. 1981;78:3418–3422. [PMC free article: PMC319579] [PubMed: 6267589]
  374. Fung Y.K., Fadly A.M., Crittenden L.B., Kung H.J. Avian lymphoid leukosis virus infection and DNA integration in the preleukotic bursal tissues: A comparative study of susceptible and resistant lines. Virology. 1982b;119:411–421. [PubMed: 6281983]
  375. Fung Y.K., Lewis W.G., Crittenden L.B., Kung H.J. Activation of the cellular oncogene c-erbB by LTR insertion: Molecular basis for induction of erythroblastosis by avian leukosis virus. Cell. 1983b;33:357–368. [PubMed: 6305505]
  376. Gabuzda D.H., Hess J.L., Small J.A., Clements J.E. Regulation of the visna virus long terminal repeat in macrophages involves cellular factors that bind sequences containing AP-1 sites. Mol. Cell. Biol. 1989;9:2728–2733. [PMC free article: PMC362346] [PubMed: 2548087]
  377. Gale N.W., Kaplan S., Lowenstein E., Schlessinger J., Bar-Sagi D. Grb2 mediates the EGF dependent activation of guanine nucleotide exchange on Ras. Nature. 1993;363:88–92. [PubMed: 8386805]
  378. Gallahan D., Callahan R. Mammary tumorigenesis in feral mice: Identification of a new int locus in mouse mammary tumor virus (Czech II)-induced mammary tumors. J. Virol. 1987;61:66–74. [PMC free article: PMC255203] [PubMed: 3023708]
  379. Gallahan D., Kozak C., Callahan R. A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17. J. Virol. 1987;61:218–220. [PMC free article: PMC255246] [PubMed: 3023699]
  380. Gallart T., Anegeon I., Woessner S., de la Fuente R., Florensa L., Sans-Sabrafren C., Vives J. Clinically benign adult T-cell chronic lymphocytosis with unusual phenotype. Lancet. 1983;I:769–770. [PubMed: 6132115]
  381. Gallo R.C., Sliski A., Wong-Staal F. Origin of human T-cell leukaemia-lymphoma virus. Lancet. 1983;II:962–963. [PubMed: 6138516]
  382. Gamett D.C., Tracy S.E., Robinson H.L. Differences in sequences encoding the carboxyl-terminal domain of the epidermal growth factor receptor correlate with differences in the disease potential of viral erbB genes. Proc. Natl. Acad. Sci. 1986;83:6053–6057. [PMC free article: PMC386436] [PubMed: 3016739]
  383. Garcia M., Wellinger R., Vessaz A., Diggelmann H. A new site of integration for mouse mammary tumor virus proviral DNA common to BALB/cf(C3H) mammary and kidney adenocarcinomas. EMBO J. 1986;5:127–134. [PMC free article: PMC1166704] [PubMed: 3007110]
  384. Gardner M.B. Type C viruses of wild mice: Characterization and natural history of amphotropic, ecotropic, and xenotropic MuLV. Curr. Top. Microbiol. Immunol. 1978;79:215–259. [PubMed: 206407]
  385. Gardner M.B., Kozak C.A., O'Brien S.J. The Lake Casitas wild mouse: Evolving genetic resistance to retroviral disease. Trends Genet. 1991;7:22–27. [PubMed: 1848377]
  386. Gardner M.B., Rasheed S., Pal B.K., Estes J.D., O'Brien S.J. Akvr-1, a dominant murine leukemia virus restriction gene, is polymorphic in leukemia-prone wild mice. Proc. Natl. Acad. Sci. 1980;77:531–535. [PMC free article: PMC348306] [PubMed: 6244564]
  387. Gardner M.B., Arnstein P., Rongey R.W., Estes J.D., Sarma P.S., Rickard C.F., Huebner R.J. Experimental transmission of feline fibrosarcoma to cats and dogs. Nature. 1970;226:807–809. [PubMed: 5444620]
  388. Gardner M.B., Henderson B.E., Officer J.E., Rongey R.W., Parker J.C., Oliver C., Estes J.D., Huebner R.J. A spontaneous low motor neuron disease apparently caused by indigenous type-C RNA virus in wild mice. J. Natl. Cancer Inst. 1973;51:1243–1254. [PMC free article: PMC7204280] [PubMed: 4355605]
  389. Gattoni-Celli S., Hsiao W.L., Weinstein I.B. Rearranged c-mos locus in a MOPC 21 murine myeloma cell line and its persistence in hybridomas. Nature. 1983;306:795–796. [PubMed: 6656882]
  390. Gazdar A.F., Linnoila R.I. The pathology of lung carcinoma: Changing concepts and newer diagnostic techniques. Semin. Oncol. 1988;15:215–222. [PubMed: 2837828]
  391. Gazdar A.F., Chopra H.C., Sarma P.S. Properties of a murine sarcoma virus isolated from a tumor arising in an NZW/ NZB F1 hybrid mouse. I. Isolation and pathology of tumors induced in rodents. Int. J. Cancer. 1972;9:219–233. [PubMed: 4335642]
  392. Gazzolo L., Moscovici C., Moscovici M.G., Samurat J. Response of hemopoietic cells to avian acute leukemia viruses: Effects on the differentiation of the target cells. Cell. 1979;16:683–691. [PubMed: 222465]
  393. Gazzolo L., Samurat J., Bouabdelli M., Blanchet J.P. Early precursors in the erythroid lineage are the specific target cells of avian erythroblastosis virus in vitro. Cell. 1980;22:683–691. [PubMed: 6257394]
  394. Gebriel G.M., Pevzner I.Y., Nordskog A.W. Genetic linkage between immune response to GAT and the fate of RSV-induced tumors in chickens. Immunogenetics. 1979;9:327–334.
  395. Gelinas C., Temin H. The v-rel oncogene encodes a cell-specific transcriptional activator of certain proteins. Oncogene. 1988;3:67–74. [PubMed: 2856247]
  396. Gelmann E.P., Trainor C.D., Wong-Staal F., Reitz M.S. Molecular cloning of circular unintegrated DNA of two types of the SEATO strain of gibbon ape leukemia virus. J. Virol. 1982;44:269–275. [PMC free article: PMC256262] [PubMed: 6292490]
  397. Gendelman H.E., Narayan O., Molincant S., Clements J.E., Ghobti Z. Slow, persistent replication of lentiviruses: Role of macrophages and macrophage precursors in bone marrow. Proc. Natl. Acad. Sci. 1985;82:7086–7090. [PMC free article: PMC391315] [PubMed: 2996004]
  398. Gendelman H.E., Narayan O., Kennedy-Stoskopf S., Kennedy P.G.E., Ghobti Z., Clements J.E., Stanley J., Pezeshkpour G. Tropism of sheep lentiviruses for monocytes: Susceptibility to infection and virus gene expression increase during maturation of monocytes to macrophages. J. Virol. 1986;58:67–74. [PMC free article: PMC252877] [PubMed: 3005660]
  399. George D.L., Glick B., Trusko S., Freeman N. Enhanced c-Ki-ras expression associated with Friend virus integration in a bone marrow-derived mouse cell line. Proc. Natl. Acad. Sci. 1986;83:1651–1655. [PMC free article: PMC323141] [PubMed: 3513183]
  400. Georgsson G. Neuropathologic aspects of lentiviral infections. Ann. N.Y. Acad. Sci. 1994;724:50–67. [PubMed: 8030977]
  401. Gerondakis S., Bishop J.M. Structure of the protein encoded by the chicken proto-oncogene c-myb. Mol. Cell. Biol. 1986;6:3677–3684. [PMC free article: PMC367128] [PubMed: 3025608]
  402. Gessain A., Gout O. Chronic myelopathy associated with human T-lymphotropic virus type I (HTLV-I). Ann. Intern. Med. 1992;11:933–946. [PubMed: 1443956]
  403. Gessain A., Gallo R.C., Franchini G. Low degree of human T-cell leukemia/lymphoma virus type I genetic drift in vivo as a means of monitoring viral transmission and movement of ancient human populations. J. Virol. 1992;66:2288–2295. [PMC free article: PMC289023] [PubMed: 1548762]
  404. Gessain A., Boeri E., Yanagihara R., Gallo R.C., Franchini G. Complete nucleotide sequence of a highly divergent human T-cell leukemia (lymphotropic) virus type I (HTLV-I) variant from Melanesia: Genetic and phylogenetic relationship to HTLV-I strains from other geographical regions. J. Virol. 1993;67:1015–1023. [PMC free article: PMC237456] [PubMed: 8419636]
  405. Gessain A., Barin F., Vernant J.C., Gout O., Maurs L., Calender A., de Thé G. Antibodies to human T-lymphotropic virus type I in patients with tropical spastic paraparesis. Lancet. 1985;II:407–410. [PubMed: 2863442]
  406. Gessain A., Mauclere P., Froment A., Biglione M., Le Hesran J.Y., Tekaia F., Millan J., de Thé G. Isolation and molecular characterization of a human T-cell lymphotropic virus type II (HTLV-II), subtype B, from a healthy Pygmy living in a remote area of Cameroon: An ancient origin for HTLV-II in Africa. Proc. Natl. Acad. Sci. 1995;92:4041–4045. [PMC free article: PMC42098] [PubMed: 7732027]
  407. Gessain A., Saal F., Gout O., Daniel M.T., Flandrin G., de Thé G., Periers J., Sigaux F. High human lymphotropic virus type I proviral DNA load with polyclonal integration in peripheral blood mononuclear cells of French West Indian, Guianese, and African patients with tropical spastic paraparesis. Blood. 1990;75:428–433. [PubMed: 1967218]
  408. Gessain A., Saal F., Morozov V., Lasneret J., Vilette D., Gout O., Emanoil-Ravier R., Sigaux F., de Thé G., Peries J. Characterization of HTLV-I isolates and T lymphoid cell lines derived from French West Indian patients with tropical spastic paraparesis. Int. J. Cancer. 1989;43:327–333. [PubMed: 2563721]
  409. Gibbs J.B., Sigal I.S., Poe M., Scolnick E.M. Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules. Proc. Natl. Acad. Sci. 1984;81:5704–5708. [PMC free article: PMC391779] [PubMed: 6148751]
  410. Giese N.A., Giese T., Morse H.C. III. Murine AIDS is an antigen-driven disease: Requirements for major histocompatibility complex class II expression and CD4+ T cells. J. Virol. 1994;68:5819–5824. [PMC free article: PMC236986] [PubMed: 7914549]
  411. Gilks C.B., Bear S.E., Grimes H.L., Tsichlis P.N. Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein. Mol. Cell. Biol. 1993;13:1759–1768. [PMC free article: PMC359488] [PubMed: 8441411]
  412. Gilmore G.L., Cowing C., Mosier D.E. LP-BM5 murine retrovirus-induced immunodeficiency disease in allogeneic SCID chimeric mice. Inability to recognize a putative viral superantigen does not prevent induction of disease. J. Immunol. 1993;150:185–189. [PubMed: 8380187]
  413. Girard L., Hanna Z., Beaulie N., Simard C., Kozak C.A., Hoemann C., Jolicoeur P. Frequent provirus insertional mutagenesis of Notch1 in thymoma of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis. Genes Dev. 1996;10:1930–1944. [PubMed: 8756350]
  414. Gisselbrecht S., Fichelson S., Sola B., Bordereaux D., Hampe A., Andre C., Galibert F., Tambourin P. Frequent c-fms activation by proviral insertion in mouse myeloblastic leukaemias. Nature. 1987;329:259–261. [PubMed: 3476856]
  415. Gogolewski R.P., Adams D.S., McGuire T.C., Banks K.L., Cheevers W.P. Antigenic cross-reactivity between caprine arthritis-encephalitis, visna and progressive pneumonia viruses involves all virion-associated proteins and glycoproteins. J. Gen. Virol. 1985;66:1233–1240. [PubMed: 2409223]
  416. Golay J., Introna M., Graf T. A single point mutation in the v-ets oncogene affects both erythroid and myelomonocytic cell differentiation. Cell. 1988;55:1147–1158. [PubMed: 3203383]
  417. Golemis E., Li Y., Fredrickson T.N., Hartley J.W., Hopkins N. Distinct segments within the enhancer region collaborate to specify the type of leukemia induced by nondefective Friend and Moloney viruses. J. Virol. 1989;63:328–337. [PMC free article: PMC247688] [PubMed: 2783259]
  418. Golovkina T.V., Jaffe A.B., Ross S.R. Coexpression of exogenous and endogenous mouse mammary tumor virus RNA in vivo results in viral recombination and broadens host range. J. Virol. 1994;68:5019–5026. [PMC free article: PMC236444] [PubMed: 8035502]
  419. Golovkina T.V., Chervonsky A., Dudley J.P., Ross S.R. Transgenic mouse mammary tumor virus superantigen expression prevents viral infection. Cell. 1992;69:637–645. [PubMed: 1316806]
  420. Golovkina T.V., Dudley J.P., Jaffe A.B., Ross S.R. Mouse mammary tumor viruses with functional superantigen genes are selected during in vivo infection. Proc. Natl. Acad. Sci. 1995;92:4828–4832. [PMC free article: PMC41800] [PubMed: 7761408]
  421. Gonda T.J., Cory S., Sobieszczuk P., Holtzman D., Adams J.M. Generation of altered transcripts by retroviral insertion within the c-myb gene in two murine monocytic leukemias. J. Virol. 1987;61:2754–2763. [PMC free article: PMC255783] [PubMed: 2441077]
  422. Gonzalez L., Juste R.A., Cuervo L.A., Idigoras I., Saez de Ocariz C. Pathological and epidemiological aspects of the coexistence of maedi-visna and sheep pulmonary adenomatosis. Res. Vet. Sci. 1993;54:140–146. [PubMed: 8384727]
  423. Goodenow M.M., Hayward W.S. 5′ Long terminal repeats of myc-associated proviruses appear structurally intact but are functionally impaired in tumors induced by avian leukosis viruses. J. Virol. 1987;61:2489–2498. [PMC free article: PMC255678] [PubMed: 3037111]
  424. Goodwin R.G., Rottman F.M., Callaghan T., Kung H.J., Maroney P.A., Nilsen T.W. c-erbB Activation in avian leukosis virus-induced erythroblastosis: Multiple epidermal growth factor receptor mRNAs are generated by alternative RNA processing. Mol. Cell. Biol. 1986;6:3128–3133. [PMC free article: PMC367047] [PubMed: 3023963]
  425. Gotoh Y., Sugamura K., Hinuma Y. Healthy carriers of a human retrovirus, adult T-cell leukemia virus (ATLV): Demonstration by clonal culture of ATLV-carrying T cells from peripheral blood. Proc. Natl. Acad. Sci. 1982;79:4780–4782. [PMC free article: PMC346761] [PubMed: 6289319]
  426. Graf T., Beug H. Avian leukemia viruses interaction with their target cells in vivo and in vitro. Biochim. Biophys. Acta. 1978;516:269–299. [PubMed: 215208]
  427. Graf T., Ade N., Beug H. Temperature sensitive mutant of avian erythroblastosis virus suggests a block of differentiation as mechanism of leukemogenesis. Nature. 1978;275:496–501. [PubMed: 211440]
  428. Graf T., Beug H., Hayman M. Target cell specificity of defective avian leukemia viruses: Hematopoietic target cells for a given virus type can be infected but not transformed by strains of a different types. Proc. Natl. Acad. Sci. 1980;77:389–393. [PMC free article: PMC348276] [PubMed: 6244556]
  429. Graf T., von Kirchback A., Beug H. Characterization of the hematopoietic target cells of AEV, MC29 and AMV avian leukemia viruses. Exp. Cell Res. 1981;131:331–343. [PubMed: 6258948]
  430. Graf T., McNagny K., Brady G., Frampton J. Chicken “erythroid” cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent. Cell. 1992;70:201–213. [PubMed: 1322247]
  431. Graf T., Von Weizsaecker F., Grieser S., Coll J., Stehlin D., Patschinsky T., Bister K., Bechade C., Calothy G., Leutz A. v-mil Induces autocrine growth and enhanced tumorigenicity in v-myc-transformed avian macrophages. Cell. 1986;45:357–364. [PubMed: 3698101]
  432. Graffi A. Chloroleukemia of mice. Ann. N.Y. Acad. Sci. 1957;68:540–558. [PubMed: 13488305]
  433. Graham M., Adams J.M., Cory S. Murine T lymphomas with retroviral inserts in the chromosomal 15 locus for plasmacytoma variant translocations. Nature. 1985;314:740–743. [PubMed: 3990802]
  434. Grassmann R., Berchtolds S., Radant I., Alt M., Fleckenstein B., G. Sodroski J., Haseltine W.A., Ramstedt U. Role of human T-cell leukemia virus type I X region proteins in immortalization of primary human lymphocytes in culture. J. Virol. 1992;66:4570–4575. [PMC free article: PMC241270] [PubMed: 1351105]
  435. Grassmann R., Dengler C., Muller-Fleckenstein I., Fleckensten B., McGuire K., Dokhelar M.C., Sodroski J.G., Haseltine W.A. Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector. Proc. Natl. Acad. Sci. 1989;86:3351–3355. [PMC free article: PMC287130] [PubMed: 2541443]
  436. Gravel C., Kay D.G., Jolicoeur P. Identification of the infected target cell type in spongiform myeloencephalopathy induced by the neurotropic Cas-Br-E murine leukemia virus. J. Virol. 1993;67:6648–6658. [PMC free article: PMC238103] [PubMed: 8411367]
  437. Gray D.A., McGrath C.M., Jones R.F., Morris V.L. A common mouse mammary tumor virus integration site in chemically induced precancerous mammary hyperplasias. Virology. 1986;148:360–368. [PubMed: 3002039]
  438. Greco R.J., Steiner R.M., Goldman S., Colter H., Patchefesky A., Cohn H.E. Bronchioalveolar cell carcinoma of the lung. Ann. Thorac. Surg. 1986;41:652–656. [PubMed: 3013107]
  439. Green N., Hiai H., Elder J.H., Schwartz R.S., Khiroya R.H., Thomas C.Y., Tsichlis P.N., Coffin J.M. Expression of leukemogenic recombinant viruses associated with a recessive gene in HRS/J mice. J. Exp. Med. 1980;152:249–264. [PMC free article: PMC2185945] [PubMed: 7400758]
  440. Green P.L., Chen I.S.Y. 1994Molecular features of the human T-cell leukemia virus. Mechanisms of transformation and leukemogenicity In The retroviridae (ed. J. Levy), pp. 277–311. Plenum Press, New York.
  441. Green P.L., Kaehler D.A., Risser R. Cell transformation and tumor induction by Abelson murine leukemia virus in the absence of helper virus. Proc. Natl. Acad. Sci. 1987a;84:5932–5936. [PMC free article: PMC298977] [PubMed: 3039515]
  442. Green P.L., Kaehler D.A., Risser R. Clonal dominance and progression in Abelson murine leukemia virus lymphomagenesis. J. Virol. 1987b;61:2192–2197. [PMC free article: PMC283682] [PubMed: 3035219]
  443. Green P.L., Kaehler D.A., Bennett L.M., Risser R. Multiple steps are required for the induction of tumors by Abelson murine leukemia virus. J. Virol. 1989;63:1989–1994. [PMC free article: PMC250613] [PubMed: 2539498]
  444. Green P.L., Kaehler D.A., McKearn J., Risser R. Substitution of the LTR of Abelson murine leukemia virus does not alter the cell type of virally induced tumors. Oncogene. 1988;2:585–592. [PubMed: 2838788]
  445. Greenberg M.E., Ziff E.B. Stimulation of 3T3 cells induced transcription of the c-fos proto-oncogene. Nature. 1984;311:711–714. [PubMed: 6090941]
  446. Greenberg R., Hawley R., B. Marcu K. Acquisition of an intracisternal A-particle element by a translocated c-myc gene in a murine plasma cell tumor. Mol. Cell. Biol. 1985;5:3625–3628.
  447. Greenberg S., Jacobson S., Waldmann T.A., McFarlin D.E. Molecular analysis of HTLV-I proviral integration and T cell receptor rearrangement indicates that T cells in tropical spastic paraparesis are polyclonal. J. Infect. Dis. 1989;159:741–744. [PubMed: 2538520]
  448. Gregoire D., Couez D., Dsechamps J., Heurtz S., Hors-Cayla M.-C., Szpirer J., Burny A., Huez G., Kettmann R. Different bovine leukemia virus-induced tumors harbor the provirus in different chromosomes. J. Virol. 1984;50:275–279. [PMC free article: PMC255611] [PubMed: 6321797]
  449. Grindem C.B., Corbett W.T., Ammermann B.E., Tomkins M.T. Seroepidemiologic survey of feline immunodeficiency virus infection in cats of Wake County, North Carolina. J. Am. Vet. Med. Assoc. 1989;194:226–228. [PubMed: 2537271]
  450. Gross L. 1970Oncogenic viruses Pergamon Press, Elmsford, New York.
  451. Grossman W.J., Kimata J.T., Wong F.H., Zutter M., Ley T.J., Ratner L. Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I. Proc. Natl. Acad. Sci. 1995;92:1057–1061. [PMC free article: PMC42636] [PubMed: 7862633]
  452. Haase A.T. Pathogenesis of lentivirus infections. Nature. 1986;322:130–136. [PubMed: 2425264]
  453. Haase A.T., Retzel E.F., Staskus K.A. Amplification and detection of lentiviral DNA insider cells. Proc. Natl. Acad. Sci. 1990;87:4971–4975. [PMC free article: PMC54243] [PubMed: 2164214]
  454. Haase A.T., Stowring L., Harris J.D., Traymor B., Ventura P., Peluso R., Brahic M. Visna DNA synthesis and the tempo of infection in vitro. Virology. 1982;119:399–410. [PubMed: 6281982]
  455. Habets G., Scholtes E.H., Zuydgeest D., Van der Kammen R.A., Stam J.C., Berns A., Collard J.G. Identification of an invasion-inducing gene, Tiam1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell. 1994;77:537–549. [PubMed: 7999144]
  456. Hall W.J., Bean C.W., Pollard M. Transmission of fowl leukosis through chick embryos and young chicks. Am. J. Vet. Res. 1941;2:272–279.
  457. Hallenberg B., Schmidt J., Luz A., Pedersen F.S., Grundstrom T. SL3-3 enhancer factor 1 transcriptional activators are required for tumor formation by SL3-3 murine leukemia virus. J. Virol. 1991;65:4177–4181. [PMC free article: PMC248852] [PubMed: 1649324]
  458. Halpern C.C., Hayward W.S., Hanafusa H. Characterization of some isolates of newly recovered avian sarcoma virus. J. Virol. 1979;29:91–101. [PMC free article: PMC353080] [PubMed: 219237]
  459. Hammond C.I., Vogt P.K., Bishop J.M. Molecular cloning of the PRCII sarcoma viral genome and the chicken proto-oncogene c-fps. Virology. 1985;143:300–308. [PubMed: 2998006]
  460. Hampe A., Laprevotte I., Galibert F., Fedele L.A., Sherr C.J. Nucleotide sequences of feline retroviral oncogenes (v-fes) provide evidence for a family of tyrosine-specific protein kinase genes. Cell. 1982;30:775–785. [PubMed: 6183005]
  461. Han X.D., Wong P.M., Chung S.W. Chronic myeloproliferative disease induced by site-specific integration of Abelson murine leukemia virus-infected hemopoietic stem cells. Proc. Natl. Acad. Sci. 1991;88:10129–10133. [PMC free article: PMC52881] [PubMed: 1682923]
  462. Hanafusa H., Halpern C.C., Buchhagen D.L., Kawai S. Recovery of avian sarcoma viruses from tumors inducer by transformation data. J. Exp. Med. 1977;146:1735–1747. [PMC free article: PMC2181894] [PubMed: 200700]
  463. Hanaoka M., Takatsuki K., Shimoyama M. Adult T-cell leukemia and related disease. Gann Monogr. Cancer Res. 1982;28:1–237.
  464. Hanecak R., Pattengale P.K., Fan H. Addition of substitution of simian virus 40 enhancer sequences into the Moloney murine leukemia virus (M-MuLV) long terminal repeat yields infectious M-MuLV with altered biological properties. J. Virol. 1988;62:2427–2436. [PMC free article: PMC253401] [PubMed: 2836623]
  465. Hankins W.D., Troxler D. Polycythemia- and anemia-binding erythroleukemia viruses exhibit differential erythroid transforming effects in vitro. Cell. 1980;22:693–699. [PubMed: 6936081]
  466. Hann S.R., Thompson C.B., Eisenman R.N. c-myc Oncogenic protein synthesis is independent of the cell cycle in human and avian cells. Nature. 1985;314:366–369. [PubMed: 3885045]
  467. Hanna Z., Jankowski M., Tremblay P.J., Jiang X., Milatovich A., Francke U., Jolicoeur P. The vin1 gene, identified by provirus insertional mutagenesis, is the cyclin D2. Oncogene. 1993;8:1661–1666. [PubMed: 8502486]
  468. Hannink M., Donoghue D.J. Requirement for a signal sequence in biological expression of the v-sis oncogene. Science. 1984;226:1197–1199. [PubMed: 6095451]
  469. Hannink M., Donoghue D.J. Lysine residue 121 in the proposed ATP-binding site of the v-mos protein is required for transformation. Proc. Natl. Acad. Sci. 1985;82:7894–7898. [PMC free article: PMC390876] [PubMed: 2999782]
  470. Hannink M., Donoghue D.J. Autocrine stimulation by the v-sis gene product requires a ligand-receptor interaction at the cell surface. J. Cell Biol. 1988;107:287–298. [PMC free article: PMC2115171] [PubMed: 2455725]
  471. Hannink M., Temin H.M. Transctivation of gene expression by nuclear and cytoplasmic rel proteins. Mol. Cell. Biol. 1989;9:4323–4336. [PMC free article: PMC362513] [PubMed: 2555689]
  472. Hara H., Morita M., Iwaki T., Hatae T., Itoyama Y., Kitamoto T., Akizuki S., Goto I., Watanabe T. Detection of human T lymphotrophic virus type I (HTLV-I) proviral DNA and analysis of T cell receptor Vß CDR3 sequences in spinal cord lesions of HTLV-I-associated myelopathy/tropical spastic paraparesis. J. Exp. Med. 1994;180:831–839. [PMC free article: PMC2191665] [PubMed: 8064235]
  473. Hara Y., Ishida T., Ejima H., Tagawa M., Motoyoshi S., Tomoda I., Shimizu M., Shichinohe K. Decrease in mitogen-induced lymphocyte proliferative responses in cats infected with feline immunodeficiency virus. Jpn. J. Vet. Sci. 1990;52:573–579. [PubMed: 2166852]
  474. Haran-Ghera N. Potential leukemic cells among bone marrow cells of young AKR/J mice. Proc. Natl. Acad. Sci. 1980;77:2923–2926. [PMC free article: PMC349518] [PubMed: 6967216]
  475. Haran-Ghera N., Peled A. Induction of leukemia in mice by irradiation and radiation leukemia virus variants. Adv. Cancer Res. 1979;30:45–87. [PubMed: 228537]
  476. Hardy W.D. 1980Feline leukemia virus diseases In Feline leukemia virus (ed. W.D. Hardy et al.), pp. 3–31. Elsevier/North Holland, New York.
  477. Hardy W.D. Immunopathology induced by the feline leukemia virus. Springer Semin. Immunopathol. 1982;5:75–106. [PubMed: 6195744]
  478. Hardy W.D. 1993Feline oncoretroviruses In The retroviridae (ed. J.A. Levy), vol. 3, pp. 109–180. Plenum Press, New York. [PMC free article: PMC46048]
  479. Hart K.C., Xu Y.F., Meyer A.N., Lee B.A., Donoghue D.J. The v-sis oncoprotein loses transforming activity when targeted to the early Golgi complex. J. Cell Biol. 1994;127:1843–1857. [PMC free article: PMC2120273] [PubMed: 7806564]
  480. Hartley J.W., Rowe W.P. Production of altered cell foci in tissue culture by defective Moloney sarcoma virus particles. Proc. Natl. Acad. Sci. 1966;55:780–786. [PMC free article: PMC224229] [PubMed: 5219685]
  481. Hartley J.W., Rowe W.P. Naturally occurring murine leukemia viruses in wild mice: Characterization of new “amphotropic” class. J. Virol. 1976;19:19–25. [PMC free article: PMC354828] [PubMed: 59816]
  482. Hartley J.W., Rowe W.P., Huebner R.J. Host-range restrictions of murine leukemia viruses in mouse embryo cell cultures. J. Virol. 1970;5:221–225. [PMC free article: PMC375990] [PubMed: 4317349]
  483. Hartley J.W., Yetter R.A., Morse H.C. III. A mouse gene on chromosome 5 that restricts infectivity of mink cell focus-forming recombinant murine leukemia viruses. J. Exp. Med. 1983;158:16–24. [PMC free article: PMC2187076] [PubMed: 6306133]
  484. Hartley J.W., Wolford N.K., Old L.J., Rowe W.P. A new class of murine leukemia virus associated with development of spontaneous lymphomas. Proc. Natl. Acad. Sci. 1977;74:789–792. [PMC free article: PMC392380] [PubMed: 191826]
  485. Hartley J.W., Fredrickson T.N., Yetter R.A., Makino M., Morse H.C. III. Retrovirus-induced murine acquired immunodeficiency syndrome: Natural history of infection and differing susceptibility of inbred mouse strains. J. Virol. 1989;63:1223–1231. [PMC free article: PMC247818] [PubMed: 2536830]
  486. Harvey J.J. An unidentified virus which causes the rapid production of tumors in mice. Nature. 1964;204:1104–1105. [PubMed: 14243400]
  487. Hasenkrug K.J., Valenzuela A., Letts V.A., Nishio J., Cheseboro B., Frankel W.N. Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus. J. Virol. 1995;69:2617–2610. [PMC free article: PMC188941] [PubMed: 7884913]
  488. Hattori T., Uchiyama T., Toibana T., Takatsuki K., Uchino H. Surface phenotype of Japanese adult T-cell leukemia cells characterized by monoclonal antibodies. Blood. 1981;58:645–647. [PubMed: 6455129]
  489. Haupt Y., Harris A.W., Adams J.M. Retroviral infection accelerates T lymphomagenesis in Eμ-N-ras transgenic mice by activating c-myc or N-myc. Oncogene. 1992;7:981–986. [PubMed: 1570158]
  490. Haupt Y., Harris A.W., Adams J.M. Moloney virus induction of T-cell lymphomas in a plasmacytomagenic strain of Eμ-v-abl transgenic mice. Int. J. Cancer. 1993;55:623–629. [PubMed: 8406991]
  491. Haupt Y., Alexander W.S., Barri G., Klinken S.P., Adams J.M. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice. Cell. 1991;65:753–763. [PubMed: 1904009]
  492. Hayman M.J., Beug H. Avian erythroblastosis: A model system to study oncogene cooperativity in leukemia. Cancer Surv. 1992;15:53–68. [PubMed: 1451114]
  493. Hayman M.J., Meyer S., Martin F., Steinlein P., Beug H. Self renewal and differentiation of normal avian erythroid progenitor cells: Regulatory roles of the c-erbB/TGFα receptor and the c-kit/SCF receptor. Cell. 1993;74:157–169. [PubMed: 7687522]
  494. Hayward W.S., Neel B.G., Astrin S.M. Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis. Nature. 1981;290:475–480. [PubMed: 6261142]
  495. Hecht S.J., Carlson J.O., DeMartini J.C. Analysis of a type D retroviral capsids gene expressed in ovine pulmonary carcinoma and present in both affected and unaffected sheep genomes. Virology. 1994;202:480–484. [PubMed: 8009860]
  496. Heidecker G., Huleihel M., Cleveland J.L., Kolch W., Beck T.W., Lloyd P., Pawson T., Rapp U.R. Mutational activation of c-raf1 and definition of the minimal transforming sequence. Mol. Cell. Biol. 1990;10:2503–2512. [PMC free article: PMC360607] [PubMed: 2188091]
  497. Held W., Waanders G.A., Acha-Orbea H., MacDonald H.R. Reverse transcriptase-dependent and -independent phases of infection with mouse mammary tumor virus: Implications for superantigen function. J. Exp. Med. 1994;180:2347–2351. [PMC free article: PMC2191775] [PubMed: 7525852]
  498. Held W., Waanders G.A., Shakhov A.N., Scarpellino L., Acha-Orbea H., MacDonald H.R. Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission. Cell. 1993a;74:529–540. [PubMed: 8394220]
  499. Held W., Shakhov A.N., Izui S., Waanders G.A., Scarpellino L., MacDonald H.R., Acha-Orbea H. Superantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus. J. Exp. Med. 1993b;17:359–366. [PMC free article: PMC2190911] [PubMed: 8093892]
  500. Heldin C.-H. Dimerization of cell surface receptors in signal transduction. Cell. 1995;80:213–224. [PubMed: 7834741]
  501. Herman S.J., Coffin J.M. Differential transcription from the long terminal repeats of integrated avian leukosis virus DNA. J. Virol. 1986;60:497–505. [PMC free article: PMC288918] [PubMed: 3021984]
  502. Herr W., Gilbert W. Somatically acquired recombinant murine leukemia proviruses in thymic leukemias of AKR/J mice. J. Virol. 1983;46:70–82. [PMC free article: PMC255094] [PubMed: 6298471]
  503. Hicks G.G., Mowat M. Integration of Friend murine leukemia virus into both alleles of the p53 oncogene in an erythroleukemic cell line. J. Virol. 1988;62:4752–4755. [PMC free article: PMC253591] [PubMed: 2846884]
  504. Hihara H., Yamamoto H., Shimohira H., Arai K., Shimizu T. Avian erythroblastosis virus isolated from chick erythroblastosis induced by lymphatic leukemia virus subgroup A. J. Natl. Cancer Inst. 1983;70:891–897. [PubMed: 6302361]
  505. Hill C.S., Treisman R. Transcriptional regulation by extracellular signals: Mechanisms and specificity. Cell. 1995;80:199–212. [PubMed: 7834740]
  506. Hinds P.W., Weinberg R.A. Tumor suppressor genes. Curr. Opin. Genet. Dev. 1994;4:135–141. [PubMed: 8193533]
  507. Hino M., Tojo A., Misawa Y., Morii H., Takaku F., Shibuya M. Unregulated expression of the erythropoietin receptor gene caused by insertion of spleen focus-forming virus long terminal repeat in a murine erythroleukemia cell line. Mol. Cell. Biol. 1991;11:5527–5533. [PMC free article: PMC361922] [PubMed: 1656233]
  508. Hino S., Sugiyama H., Doi H., Ishimaru T., Yamabe T., Tsuji Y., Miyamoto T. Breaking the cycle of HTLV-I transmission via carrier mother's milk. Lancet. 1987;II:158–159. [PubMed: 2885619]
  509. Hinrichs S.H., Nerenberg M., Reynolds R.K., Khoury G., Jay G. A transgenic model for human neurofibromatosis. Science. 1987;237:1340–1343. [PubMed: 2888191]
  510. Hinuma Y. Seroepidemiology of adult T-cell leukemia virus (HTLV-I/ATLV): Origin of virus carriers in Japan. AIDS Res. 1986;2:517–522. [PubMed: 2881555]
  511. Hinuma Y., Nagata K., Hanaoka M., Nakai M., Matsumoto T., Kinoshita K.-I., Shirakawa S., Miyoshi I. Adult T-cell leukemia: Antigen in an ATL cell line and detection of antibodies to the antigen in human sera. Proc. Natl. Acad. Sci. 1981;78:6476–6480. [PMC free article: PMC349062] [PubMed: 7031654]
  512. Hinuma Y., Komoda H., Chosa T., Kondo T., Kohakura M., Takenaka T., Kikuchi M., Ichimaur M., Yunoki K., Sato I., Matsuo R., Takiuchi Y., Uchino H., Hanaoka M. Antibodies to adult T-cell leukemia-virus-associated antigen (ATLA) in sera from patients with ATL and controls in Japan: A nationwide seroepidemiologic study. Int. J. Cancer. 1982;29:631–635. [PubMed: 6980846]
  513. Hirata M., Hayashi J., Noguchi A., Nakashima K., Kajiyama W., Kashiwagi S., Sawada T. The effects of breastfeeding and presence of antibody to p40(tax) protein of human T cell lymphotropic virus type-I on mother to child transmission. Int. J. Epidemiol. 1992;21:989–994. [PubMed: 1468864]
  514. Hirose S., Uemura Y., Fujishita M., Kitagawa T., Yamashita M., Imamura J., Uhtsuki Y., Taguchi H., Miyoshi I. Isolation of HTLV-I from cerebrospinal fluid of a patient with myelopathy. Lancet. 1986;II:397–398. [PubMed: 2874393]
  515. Hitoshi Y., Okada Y., Sonoda E., Tominaga A., Makino M., Suzuki K., Kinoshita J., Komuro K., Mizuochi T., Takatsu K. Delayed progression of a murine retrovirus-induced acquired immunodeficiency syndrome in X-linked immunodeficient mice. J. Exp. Med. 1993;177:621–626. [PMC free article: PMC2190950] [PubMed: 8382252]
  516. Hjelle B., Zhu S.W., Takahashi H., Ijichi S., Hall W.W. Endemic human T cell leukemia virus type II infection in southwestern US Indians involves two prototype variants of virus. J. Infect. Dis. 1993;168:737–740. [PubMed: 8354915]
  517. Ho D.D., Rota R.T., Hirsch M.S. Infection of human endothelial cells by human T-lymphotropic virus type-I. Proc. Natl. Acad. Sci. 1984;81:7588–7590. [PMC free article: PMC392192] [PubMed: 6095308]
  518. Hoatlin M.E., Ferro F.E. Jr., Geib R.W., Fox M.T., Kozak S.L., Kabat D. Deletions in one domain of the Friend virus-encoded membrane glycoprotein overcome host range restrictions for erythroleukemia. J. Virol. 1995;69:856–863. [PMC free article: PMC188652] [PubMed: 7815553]
  519. Hoatlin M.E., Kozak S.L., Lilly F., Chakraborti A., Kozak C.A., Kabat D. Activation of erythropoietin receptors by Friend virus gp55 and by erythropoietin and down-modulation by the murine Fv-2r resistance gene. Proc. Natl. Acad. Sci. 1990;87:9985–9989. [PMC free article: PMC55299] [PubMed: 2175917]
  520. Hoffman P.M., Morse H.C. Host genetic determinants of neurological disease induced by Cas-Br-M murine leukemia virus. J. Virol. 1985;53:40–43. [PMC free article: PMC254975] [PubMed: 2981360]
  521. Hoffman P.M., Robbins D.S., Morse H.C. Role of immunity in age-related resistance to paralysis after murine leukemia virus infection. J. Virol. 1984;52:734–738. [PMC free article: PMC254590] [PubMed: 6092705]
  522. Hoffman P.M., Davidson W.F., Ruscetti S.K., Chused T.M., Morse H.C. III. Wild mouse ecotropic murine leukemia virus infection of inbred mice: Dual-tropic virus expression precedes the onset of paralysis and lymphoma. J. Virol. 1981;39:597–602. [PMC free article: PMC171369] [PubMed: 6268845]
  523. Hoffman P.M., Cimino E.F., Robbins D.S., Broadwell R.D., Powers J.M., Ruscetti S.K. Cellular tropism and localization in the rodent nervous system of a neuropathogenic variant of Friend murine leukemia virus. Lab. Invest. 1992a;67:314–321. [PubMed: 1405490]
  524. Hoffman P.M., Dhib-Jalbut S., Mikovits J.A., Robbins D.S., Wolf A.L., Bergey G.K., Lohrey N.C., Weislow O.S., Ruscetti F.W. Human T-cell leukemia virus type I infection of monocytes and microglial cells in primary human cultures. Proc. Natl. Acad. Sci. 1992b;89:11784–11788. [PMC free article: PMC50641] [PubMed: 1465399]
  525. Holland C.A., Hartley J.W., Rowe W.P., Hopkins N. At least four viral genes contribute to the leukemogenicity of murine retrovirus MCF 247. J. Virol. 1985;53:158–165. [PMC free article: PMC254998] [PubMed: 2981335]
  526. Holland C.A., Thomas C.Y., Chattopadhyay S.K., Koehne C., O'Donnell P.V. Influence of enhancer sequences on thymotropism and leukemogenicity of mink cell focus-forming viruses. J. Virol. 1989;63:1284–1292. [PMC free article: PMC247825] [PubMed: 2536834]
  527. Hollsberg P., Hafler D.A. Seminars in medicine of the Beth Israel Hospital, Boston. Pathogenesis of diseases induced by human lymphotropic virus type I infection. N. Engl. J. Med. 1993;328:1173–1182. [PubMed: 8455685]
  528. Hollsberg P., Hafler D.A. What is the pathogenesis of human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis? Ann. Neurol. 1995;37:143–145. [PubMed: 7847855]
  529. Holmes K.L., Morse H.C. III, Makino M., Hardy R.R., Hayakawa K. A unique subset of normal murine CD4+ T cells lacking Thy-1 is expanded in a murine retrovirus-induced immunodeficiency syndrome, MAIDS. Eur. J. Immunol. 1990;20:2783–2787. [PubMed: 1980114]
  530. Holzschu D.L., Martineau D., Fodor S.K., Vogt V.M., Bowser P.R., Casey J.W. Nucleotide sequence and protein analysis of a complex piscine retrovirus, walleye dermal sarcoma virus. J. Virol. 1995;69:5320–5231. [PMC free article: PMC189371] [PubMed: 7636975]
  531. Hoover E.A., Mullins J.I. Feline leukemia virus infection and diseases. J. Am. Vet. Med. Assoc. 1991;199:1287–1297. [PubMed: 1666070]
  532. Hoover E.A., Mullins J.I. 1993 FeLV-FAIDS immunodeficiency syndrome Oxford University Press, Oxford, United Kingdom. [PMC free article: PMC47900]
  533. Hoover E.A., Kociba G.J., Hardy W.D., Yohn D.S. Erythroid hypoplasia in cats inoculated with feline leukemia virus. J. Natl. Cancer Inst. 1974;53:1271–1276. [PubMed: 4372379]
  534. Hoover E.A., Mullins J.I., Quackenbush S.L., Gaspar P.W. Experimental transmission and pathogenesis of immunodeficiency syndrome in cats. Blood. 1987;70:1880–1892. [PubMed: 2823940]
  535. Horowitz M., Luria S., Rechavi G., Givol D. Mechanism of activation of the mouse c-mos oncogene by the LTR of an intracisternal A-particle gene. EMBO J. 1984;3:2937–2941. [PMC free article: PMC557792] [PubMed: 6098457]
  536. Hoshino H., Shimoyama M., Miwa M., Sugimura T. Detection of lymphocytes producing a human retrovirus associated with adult T-cell leukemia by syncytium induction assay. Proc. Natl. Acad. Sci. 1983a;80:7337–7341. [PMC free article: PMC390050] [PubMed: 6316359]
  537. Hoshino H., Esumi H., Miwa M., Shimoyama M., Minato K., Tobinai K., Hirose M., Watanabe S., Inada N., Kinoshita K., Kamihira S., Ichimaru M., Sugimura T. Establishment and characterization of 10 cell lines derived from patients with adult T-cell leukemia. Proc. Natl. Acad. Sci. 1983b;80:6061–6065. [PMC free article: PMC534360] [PubMed: 6193528]
  538. Howard J.C., Yousefi S., Cheong C., Bernstein A., Ben-David Y. Temporal order and functional analysis of mutations within the Fli-1 and p53 genes during the erythroleukaemias induced by F-MuLV. Oncogene. 1993;8:2721–2729. [PubMed: 8378083]
  539. Hoxie J.A., Matthews D.M., Cines D.B. Infection of endothelial cells by human T-cell leukemia virus type-I. Proc. Natl. Acad. Sci. 1984;81:7591–7595. [PMC free article: PMC392193] [PubMed: 6095309]
  540. Hu S., Moscovici C., Vogt P.K. The defectiveness of Mill Hill 2, a carcinoma inducing avian oncovirus. J. Virol. 1978;89:162–178. [PubMed: 210569]
  541. Huang E., Nocka K., Beier D.R., Chu T.-Y., Buck J., Lahm W.-H., Wellner D., Leder P., Besmer P. The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell. 1990;63:225–233. [PubMed: 1698557]
  542. Huang M., Jolicoeur P. Characterization of the gag fusion protein encoded by the defective Duplan retrovirus inducing murine acquired immunodeficiency syndrome. J. Virol. 1990;64:5764–5772. [PMC free article: PMC248725] [PubMed: 2243376]
  543. Huang M., Jolicoeur P. Myristylation of Pr60 gag of the murine MAIDS defective virus is required to induce disease and notably for the expansion of its target cells. J. Virol. 1994;68:5648–5655. [PMC free article: PMC236966] [PubMed: 8057445]
  544. Huang M., Simard C., Jolicoeur P. Immunodeficiency and clonal growth of target cells induced by helper-free defective retrovirus. Science. 1989;246:1614–1617. [PubMed: 2480643]
  545. Huang M., Simard C., Jolicoeur P. Susceptibility of inbred strains of mice to murine AIDS (MAIDS) correlates with target cell expansion and high expression of the defective MAIDS virus. J. Virol. 1992;66:2398–2406. [PMC free article: PMC289035] [PubMed: 1312635]
  546. Huang M., Simard C., Kay D.G., Jolicoeur P. The majority of cells infected with the defective murine AIDS virus belong to the B-cell lineage. J. Virol. 1991;65:6562–6571. [PMC free article: PMC250712] [PubMed: 1658361]
  547. Huang M., Takac M., Kozack M., Jolicoeur P. The murine AIDS defective provirus acts as an insertional mutagen in its infected target B cells. J. Virol. 1995;69:4069–4078. [PMC free article: PMC189141] [PubMed: 7769664]
  548. Huff J.L., Jelnick M.A., Borgman C.A., Lansing T.J., Parsons J.T. The protooncogene c-sea encodes a transmembrane protein-tyrosine kinase related to the Met/hepatocyte growth factor/scatter factor receptor. Proc. Natl. Acad. Sci. 1992;90:6140–6144. [PMC free article: PMC46883] [PubMed: 8392188]
  549. Hughes S.H., Shank P.R., Spector D.H., Kung H.J., Bishop J.M., Varmus H.E., Vogt P.K., Breitman M.L. Proviruses of avian sarcoma virus are terminally redundant, coextensive with unintegrated linear DNA and integrated at many sites. Cell. 1978;15:1397–1410. [PubMed: 215325]
  550. Hugin A.W., Vacchio M.S., Morse H.C. III. A virus-encoded “superantigen” in a retrovirus-induced immunodeficiency. Science. 1991;252:424–427. [PubMed: 1850169]
  551. Hunsmann G., Schneider J., Schmitt J., Yamamoto N. Detection of serum antibodies to adult T-cell leukemia virus in nonhuman primates and in people from Africa. Int. J. Cancer. 1983;32:329–332. [PubMed: 6604034]
  552. Hunter T. 1001 protein kinases redux—Towards 2000. Semin. Cell Biol. 1994;5:367–376. [PubMed: 7711285]
  553. Hunter T. Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling. Cell. 1995;80:225–236. [PubMed: 7834742]
  554. Hunter T., Sefton B. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc. Natl. Acad. Sci. 1980;77:1311–1315. [PMC free article: PMC348484] [PubMed: 6246487]
  555. Hynes N.E., Stern D.F. The biology of erbB2/neu/HER-2 and its role in cancer. Biochim. Biophys. Acta. 1994;1198:165–184. [PubMed: 7819273]
  556. Iannone R., Sherman M.P., Rodgers-Johnson P.E., Beilke M.A., Mora C.A., Amin R.M., Tinsley S.R., Papsidero L.D., Poiesz B.J., Gibbs C.J. Jr. HTLV-I DNA sequences in CNS tissue of a patient with tropical spastic paraparesis and HTLV-I-associated myelopathy. J. Acquired Immune Defic. Syndr. 1992;5:810–816. [PubMed: 1517966]
  557. Ibanez C.E., Lipsick J.S. trans-Activation of gene expression by v-myb. Mol Cell. Biol. 1990;10:2285–2293. [PMC free article: PMC360575] [PubMed: 2325652]
  558. Ihle J.N., Witthuhn B.A., Quelle F.W., Yamamoto K., Silvennoinen O. Signaling through the hematopoietic cytokine receptors. Annu. Rev. Immunol. 1995;13:369–398. [PubMed: 7612228]
  559. Ihle J.N., Smith-White B., Sisson B., Parker D., Blair D.G., Schultz A., Kozak C., Lunsford R.D., Askew D., Weinstein Y., Isfort R.J. Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia. J. Virol. 1989;63:2959–2966. [PMC free article: PMC250850] [PubMed: 2542606]
  560. Ikeda H., Odaka T. A cell membrane “gp70” associated with Fv-4 gene: Immunological characterization and tissue and strain distribution. Virology. 1984;133:65–76. [PubMed: 6199893]
  561. Ikeda H., Laigret F., Martin M.A., Repaske R. Characterization of a molecularly cloned retroviral sequence associated with fv-4 resistance. J. Virol. 1985;55:768–777. [PMC free article: PMC255061] [PubMed: 2991595]
  562. Ikeda K., Okazaki R., Inoue D., Ogata E., Matsumoto T. Transcription of the gene for parathyroid hormone-related peptide from the human is activated through a cAMP-dependent pathway by prostaglandin E1 in HTLV-I-infected T cells. J. Biol. Chem. 1993a;268:1174–1179. [PubMed: 8380405]
  563. Ikeda K., Okazaki R., Inoue D., Ogata E., Matsumoto T. Interleukin-2 increases production and secretion of parathyroid hormone-related peptide by human T cell leukemia virus type I-infected TY cells: Possible role in hypercalcemia associated with adult T cell leukemia. Endocrinology. 1993b;132:2552–2556. [PubMed: 8099324]
  564. Imamura J., Tsujimoto A., Ohta Y., Hirose S., Shimotohno K., Miwa M., Miyoshi I. DNA blotting analysis of human retroviruses in cerebrospinal fluid of spastic paraparesis patients: The viruses are identical to human T-cell leukemia virus type-1 (HTLV-1). Int. J. Cancer. 1988;42:221–224. [PubMed: 2841247]
  565. Inoue J., Seiki M., Taniguchi T., Tsuru S., Yoshida M. Induction of interleukin-2 receptor gene by p40x encoded by human T-cell leukemia virus type I. EMBO J. 1986;5:2883–2888. [PMC free article: PMC1167238] [PubMed: 3024966]
  566. Inoue J.-I., Kerr L.D., Ransone L.J., Bengel E., Hunter T., Verma I.M. c-rel activates but v-rel repressed transcription for MB sites. Proc. Natl. Acad. Sci. 1991;88:3715–3719. [PMC free article: PMC51523] [PubMed: 2023921]
  567. Introna M., Golay J., Frampton J., Nakano T., Ness S.A., Graf T. Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene. Cell. 1990;63:1287–1297. [PubMed: 2261644]
  568. Irgens K., Wyers M., Moraillon A., Parodi A., Fortuny V. Isolate d'un virus sarcomatogene feline a partir d'um fibrosarcome spontane du chat: Etude du pouvoir sarcomatogene in vivo. C.R. Acad. Sci. 1973;276:1783–1786. [PubMed: 4202597]
  569. Irie K., Gotoh Y., Yasher B.M., Errede B., Nishida E., Matsumoto K. Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase. Science. 1994;265:1716–1719. [PubMed: 8085159]
  570. Ishida T., Tomoda I. Clinical staging of feline immunodeficiency virus infection. Jpn. J. Vet. Sci. 1990;52:645–648. [PubMed: 2166854]
  571. Ishida T., Taniguchi A., Matsumura S., Wahizu T., Tomoda I. Long-term clinical observations on feline immunodeficiency virus infected asymptomatic carriers. Vet. Immunol. Immunopathol. 1992;35:15–22. [PubMed: 1337394]
  572. Ishida T., Wasizu T., Toriyabe K., Motoyoshi S., Pedersen N.C. Feline immunodeficiency virus (FIV) infection in Japan. J. Am. Vet. Med. Assoc. 1989;194:221–225. [PubMed: 2537270]
  573. Isfort R., Witter R.L., Kung H.J. c-myc activation is an unusual retrovirus-induced avian T-lymphoma resembling Marek's disease: Proviral insertion 5′ of exon one enhances the expression of an intron promoter. Oncogene Res. 1987;2:81–94. [PubMed: 3505666]
  574. Ishiguro N., Abe M., Seto K., Sakurai H., Ikeda H., Wakisaka A., Togashi T., Tateno M., Yoshiki T. A rat model of human T lymphocyte virus type I (HTLV-I) infection. 1. Humoral antibody response, provirus integration, and HTLV-I-associated myelopathy/tropical spastic paraparesis-like myelopathy in seronegative HTLV-I carrier rats. J. Exp. Med. 1992;176:981–989. [PMC free article: PMC2119376] [PubMed: 1402668]
  575. Ishimoto A., Adachi A., Sakai K., Yorifuji T., Tsuruta S. Rapid emergence of mink cell focus-forming (MCF) virus in various mice infected with NB-tropic Friend virus. Virology. 1981;113:644–655. [PubMed: 6267802]
  576. Ishimoto A., Takimoto M., Adachi A., Kakuyama M., Kato S., Kakimi K., Fukuoka K., Ogiu T., Matsuyama M. Sequences responsible for erythroid lymphod leukemia in the long terminal repeats of Friend mink cell focus-forming and Moloney murine leukemia viruses. J. Virol. 1987;61:1861–1866. [PMC free article: PMC254191] [PubMed: 3033317]
  577. Issel C.J., Coggins L. Equine infectious anemia: Current knowledge. J. Am. Vet. Med. Assoc. 1979;174:727–733. [PubMed: 218920]
  578. Issel C.J., Adams W.V., Meek L., Ochua R. Transmission of equine infectious anemia virus from horses without clinical signs of the disease. J. Am. Vet. Med. Assoc. 1982;180:272–275. [PubMed: 6276353]
  579. Issel C.J., McManus J.M., Hagius S.D., Foil L.D., Adams W.V.J., Montelaro R.C. Equine infectious anemia: Prospects for control. Dev. Biol. Stand. 1990;72:49–57. [PubMed: 2178130]
  580. Itohara S., Hirata K., Inoue M., Hatsuoka M., Sato A. Isolation of a sarcoma virus from a spontaneous chicken tumor. Gann. 1978;69:825–830. [PubMed: 220128]
  581. Itoyama T., Sadamori N., Tokunaga S., Sasagawa I., Nakamura H., Yao E., Jubashi T., Yamada Y., Keda S., Ichimaru M. Cytogenetic studies of HTLV-I carriers: A family study. Cancer Genet. Cytogenet. 1990;49:157–163. [PubMed: 2208053]
  582. Ivanov X., Mladenov Z., Nedyalkov S., Todorov T.G. Experimental investigations into avian leucoses. I. Transmission experiments of certain diseases of the avian leukosis complex, found in Bulgaria. Bull. Inst. Path. Comp. Anim. Acad. Bulg. Sci. 1962;9:5–36.
  583. Iwakura Y., Tosu M., Yoshida E., Takiguschi M., Sato K., Kitajima I., Nishioka K., Yamamoto K., Takeda T., Hatanaka M., Yamamoto H., Sekiguchi T. Induction of inflammatory arthropathy resembling rheumatoid arthritis in mice transgenic for HTLV-I. Science. 1991;253:1026–1028. [PubMed: 1887217]
  584. Jacks T., Shih T.S., Schmitt E.M., Bronson R.T., Bernards A., Weinberg R.A. Tumour predisposition in mice heterozygous for a targeted mutation in Nf1. Nat. Genet. 1994;7:353–361. [PubMed: 7920653]
  585. Jackson P., Baltimore D. N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl. EMBO J. 1989;8:449–456. [PMC free article: PMC400826] [PubMed: 2542016]
  586. Jacobson E.R., Seely J.C., Novilla M.N. Lymphosarcoma associated with virus-like intranuclear inclusions in a California king snake (Lampropeltis getulus californiae). J. Natl. Cancer Inst. 1980;65:577–583. [PubMed: 6931937]
  587. Jacobson S. Immune response to retroviruses in the central nervous system. Semin. Neurosci. 1992;4:285–290.
  588. Jacobson S., Raine C.S., Mingioloi E.S., McFarlin D.E. Isolation of an HTLV-I-like retrovirus from patients with tropical spastic paraparesis. Nature. 1988a;331:540–543. [PubMed: 2829028]
  589. Jacobson S., Shida H., McFarlin D.E., Fauci A.S., Koenig S. Circulating CD8+ cytotoxic T lymphocytes specific for HTLV-I pX in patients with HTLV-I associated neurological disease. Nature. 1990;348:245–248. [PubMed: 2146511]
  590. Jacobson S., McFarlin D.E., Robinson S., Voskuhl R., Martin R., Brewah A., Newell A.J., Koenig S. HTLV-I-specific cytotoxic T lymphocytes in the cerebrospinal fluid of patients with HTLV-I-associated neurological disease. Ann. Neurol. 1992;32:651–657. [PubMed: 1449245]
  591. Jacobson S., Zaninovic V., Mora C., Rodgers-Johnson P., Sheremata W.A., Gibbs C.J. Jr., Gadjusek C., McFarlin D.E. Immunological findings in neurological diseases associated with antibodies to HTLV-I: Activated lymphocytes in tropical spastic paraparesis. Ann. Neurol. 1988b;23 (suppl.):S196–S200. [PubMed: 2894814]
  592. Jaffe E.S., Blattner W.A., Blayney D.W., Bunn P.A. Jr., Cossman J., Robert-Guroff M., Gallo R.C. The pathologic spectrum of adult T-cell leukemia lymphoma in the United States. Am. J. Surg. Pathol. 1984;8:263–275. [PubMed: 6324600]
  593. Jahner D., Jaenisch R. Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity. Nature. 1985;315:594–597. [PubMed: 2989695]
  594. Janeway C.A. Self superantigens? Cell. 1990;63:659–661. [PubMed: 2225070]
  595. Janeway C.A. Jr., Travers P. 1994. Immunobiology: The immune system in health and disease Garland, New York.
  596. Janeway C.A., Yagi J., Conrad P.J., Katz M.E., Jones B., Vroegop S., Buxser S. T-cell responses to Mls and to bacterial proteins that mimic its behavior. Immunol. Rev. 1989;107:61–88. [PubMed: 2522086]
  597. Jansen H., Ruckert B., Lurz R., Bister K. Two unrelated cell-derived sequences in the genome of avian leukemia and carcinoma-inducing retrovirus MH2. EMBO J. 1983;2:1969–1976. [PMC free article: PMC555395] [PubMed: 6315409]
  598. Jansen H.W., Lurz R., Bister K., Bonner T.I., Mark G.E., Rapp U.R. Homologous cell-derived oncogenes in avian carcinoma virus MH2 and murine sarcoma virus 3611. Nature. 1984;307:281–284. [PubMed: 6319999]
  599. Jarrett O., Russell P.H. Differential growth and transmission in cats of feline leukaemia viruses of subgroups A and B. Int. J. Cancer. 1978;21:466–472. [PubMed: 208983]
  600. Jarrett O., Russell P.H., Hardy W.D. 1978The influence of virus subgroup on the epidemiology of feline leukaemia virus In Advances in comparative leukemia research (ed. P. Bentveltzen), pp. 25–28, Elsevier, Amsterdam.
  601. Jarrett R.F., Mitsuya H., Mann D.L., Cossman J., Broder S., Reitz M. Configuration and expression of the T-cell receptor ß chain gene in human T lymphotropic virus infected cell. J. Exp. Med. 1986;163:383–399. [PMC free article: PMC2188022] [PubMed: 3003226]
  602. Jason J.M., McDougal J.S., Cabradila C., Kalyanaraman V.S., Evatt B.L. Human T-cell leukemia virus (HTLV-I) p24 antibody in New York City blood product recipients. Am. J. Hematol. 1985;20:129–137. [PubMed: 2994470]
  603. Jensen W., Rovnak J., Cockerell G. In vivo transcription of the bovine leukemia virus tax/rex region in normal and neoplastic lymphocytes of cattle and sheep. J. Virol. 1991;65:2484–2490. [PMC free article: PMC240603] [PubMed: 1850025]
  604. Jia R., Hanafusa H. The proto-oncogene of v-eyk (v-ryk) is a novel receptor-type protein tyrosine kinase with extracellular Ig/GN-III domains. J. Biol. Chem. 1994;269:1839–1844. [PubMed: 7507487]
  605. Jia R., Mayer B.J., Hanafusa T., Hanafusa H. A novel oncogene, v-ryk, encoding a truncated receptor tyrosine kinase is transduced into the RPL30 virus without loss of viral sequences. J. Virol. 1992;66:5975–5987. [PMC free article: PMC241475] [PubMed: 1527848]
  606. Johnson G.C., Barbet A.F., Klevjer-Andersson P., McGuire T.C. Pronounced production of polyclonal immunoglobuiln G1 in the synovial fluid of goats with caprine arthritis-encephalitis virus infection. Infect. Immun. 1983;41:805–815. [PMC free article: PMC264711] [PubMed: 6307882]
  607. Johnson P., Benchimol S. Friend virus induced murine erythroleukemia: The p53 locus. Cancer Surv. 1992;12:137–151. [PubMed: 1638545]
  608. Jolicoeur P. 1990Retrovirus-induced lower motor neuron disease in mice: A model for amyotrophic lateral sclerosis and human spongiform neurological diseases In Amyotrophic lateral sclerosis: Concepts in pathogenesis and etiology (ed. A.J. Hudson), pp. 53–82. University of Toronto Press, Canada. [PMC free article: PMC54772]
  609. Jolicoeur P. The murine acquired immunodeficiency syndrome (MAIDS): An animal model to study the AIDS pathogenesis. FASEB J. 1991;5:2398–2405. [PubMed: 2065888]
  610. Jolicoeur P., Baltimore D. Effect of Fv1 gene product on proviral DNA formation and integration in cells infected with murine leukemia viruses. Proc. Natl. Acad. Sci. 1976;73:2236–2240. [PMC free article: PMC430510] [PubMed: 181748]
  611. Jolicoeur P., DesGroseillers L. Neurotropic Cas-Br-E murine leukemia virus harbors several determinants of leukemogenicity mapping in different regions of the genome. J. Virol. 1985;56:639–643. [PMC free article: PMC252625] [PubMed: 2997484]
  612. Jolicoeur P., Rassart E. Effect of Fv-1 gene product on synthesis of linear and supercoiled viral DNA in cells infected with murine leukemia virus. J. Virol. 1980;33:183–195. [PMC free article: PMC288535] [PubMed: 6245227]
  613. Jolicoeur P., Rassart E., Massee G., Paquette Y. The specificity of the disease induced by defective murine retroviruses containing abl, fos, or Ha-ras is usually not determined by their LTR. Virology. 1991a;180:831–836. [PubMed: 1846504]
  614. Jolicoeur P., Hanna Z., Aziz D., Simard C., Huang M. 1991bThe murine acquired immunodeficiency syndrome (MAIDS) induced by the Duplan strain retrovirus In Viruses that affect the immune system (ed. H. Fan et al.), pp. 113–132. American Society for Microbiology, Washington, D.C.
  615. Jolicoeur P., Rassart E., DesGroseillers L., Robitaille Y., Paquette Y., Kay D.G. Retrovirus-induced motor neuron disease of mice: Molecular basis of neurotropism and paralysis. Adv. Neurol. 1991c;56:481–493. [PubMed: 1649546]
  616. Joliot V., Boroughs K., Lasserre F., Crochet J., Dambrine G., Smith R.E., Perbal B. Pathogenic potential of myeloblastosis-associated virus: Implications of env proteins for osteopetrosis induction. Virology. 1993;195:812–819. [PubMed: 8393249]
  617. Joliot V., Martinerie C., Dambrine G., Plassiart G., Brisac M., Crochet J., Perbal B. Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas. Mol. Cell. Biol. 1992;12:10–21. [PMC free article: PMC364064] [PubMed: 1309586]
  618. Justice M.J., Morse H.C., Jenkins N.A., Copeland N.G. Identification of Evi-3, a novel common site of retroviral integration in mouse AKXD B-cell lymphomas. J. Virol. 1994;68:1293–1300. [PMC free article: PMC236582] [PubMed: 8107195]
  619. Kabat D. Molecular biology of Friend viral erythroleukemia. Curr. Top. Microbiol. Immunol. 1989;148:1–41. [PubMed: 2684547]
  620. Kabrun N., Bumstead N., Hayman M.J., Enrietto P.J. Characterization of a novel promoter insertion in the c-rel locus. Mol. Cell. Biol. 1990;10:4788–4794. [PMC free article: PMC361083] [PubMed: 2167440]
  621. Kai K., Furuta T. Isolation of paralysis-inducing murine leukemia viruses from Friend virus passaged in rats. J. Virol. 1984;50:970–973. [PMC free article: PMC255772] [PubMed: 6328027]
  622. Kakinuma S., Motokawa K., Hohdatsu T., Yamamoto J.K., Koyama H., Hashimoto H. Nucleotide sequences of feline immunodeficiency virus: Classification of Japanese isolates into two subtypes which are distinct from non-Japanese subtypes. J. Virol. 1995;69:3639–3646. [PMC free article: PMC189079] [PubMed: 7745712]
  623. Kalyanaraman V.S., Sarngadharan M.G., Robert-Guroff M., Miyoshi I., Blayney D., Golde D., Gallo R.C. A new subtype of human T-cell leukemia virus (HTLV-II) associated with a T-cell variant hairy cell leukemia. Science. 1982;218:571–571. [PubMed: 6981847]
  624. Kan N.C., Flordellis C.S., Garon C.F., Duesberg P.H., Papas T.S. Avian carcinoma virus MH2 contains a transformation-specific sequence, mht, and shares the myc sequence with MC29, CMII and OK10 viruses. Proc. Natl. Acad. Sci. 1983;80:6566–6570. [PMC free article: PMC390394] [PubMed: 6579544]
  625. Kan N.C., Flordellis C.S., Mark G.E., Duesberg P.H., Papas T.S. A common onc gene sequence transduced by avian carcinoma virus MH2 and be murine sarcoma virus 3611. Science. 1984;223:813–816. [PubMed: 6320371]
  626. Kanagawa O., Nussrallah B.A., Wiebenga M.E., Murphy K.M., Morse H.C. III, Carbone F.R. Murine AIDS superantigen reactivity of the T cells bearing Vβ5 T cell antigen receptor. J. Immunol. 1992;149:9–16. [PubMed: 1351503]
  627. Kanter M.R., Smith R.E., Hayward W.S. Rapid induction of B-cell lymphomas: Insertional activation of c-myb by avian leukosis virus. J. Virol. 1988;62:1423–1432. [PMC free article: PMC253156] [PubMed: 2831403]
  628. Kapeller R., Cantley L.C. Phosphatidylinositol 3-kinase. BioEssays. 1994;16:565–576. [PubMed: 8086005]
  629. Kappes B., Ziemiecki A., Muller R.G., Theilen G.H., Bauer H., Barnekow A. The TP1 isolate of feline sarcoma virus encodes a fgr-related oncogene lacking γ actin sequences. Oncogene. 1989;4:363–372. [PubMed: 2539576]
  630. Karapetian O., Shakhov A.N., Kraehenbuhl J.P., Acha-Orbea H. Retroviral infection of neonatal Peyer's patch lymphocytes: The mouse mammary tumor virus model. J. Exp. Med. 1994;180:1511–1516. [PMC free article: PMC2191709] [PubMed: 7931081]
  631. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem. 1995;270:16483–16486. [PubMed: 7622446]
  632. Karin M., Hunter T. Transcriptional control by protein phosphorylation: Signal transmission from the cell surface to the nucleus. Curr. Biol. 1995;5:747–757. [PubMed: 7583121]
  633. Katzav S., Martin-Zanca D., Barbacid M. VAV, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells. EMBO J. 1989;8:2283–2290. [PMC free article: PMC401160] [PubMed: 2477241]
  634. Kawai S., Hanafusa H. Genetic recombination with avian tumor virus. Virology. 1972;49:37–44. [PubMed: 4338996]
  635. Kawai S., Goto N., Kataoka K., Saegusa T., Shinno-Kohno H., Nishizawa M. Isolation of the avian transforming retrovirus, AS42, carrying the v-maf oncogene and initial characterization of its gene product. Virology. 1992;188:778–784. [PubMed: 1585647]
  636. Kawakami T.G., Kollias G.V. Jr., Holmberg C. Oncogenicity of gibbon type C-myelogenous leukemia virus. Int. J. Cancer. 1980;25:641–646. [PubMed: 6768682]
  637. Kawakami T., Sherman L., Dahlberg J., Gazit A., Yaniv A., Tronick S.R., Aaronson S.A. Nucleotide sequence analysis of equine infectious anemia virus proviral DNA. Virology. 1987;158:300–312. [PubMed: 3035786]
  638. Kawano F., Yamaguchi K., Nishimura H., Tsuda H., Takatsuki K. Variation in the clinical course of adult T-cell leukemia. Cancer. 1985;55:851–856. [PubMed: 3871346]
  639. Kay D., Gravel C., Robitaille Y., Jolicoeur P. Retrovirus-induced spongiform myeloencephalopathy in mice: Regional distribution of infected target cells and neuronal loss occurring in the absence of viral expression in neurons. Proc. Natl. Acad. Sci. 1991;88:1281–1285. [PMC free article: PMC51001] [PubMed: 1847516]
  640. Kay D.G., Gravel C., Pothier F., Laperrière A., Robitaille Y., Jolicoeur P. Neurological disease induced in transgenic mice expressing the env gene of the Cas-Br-E murine retrovirus. Proc. Natl. Acad. Sci. 1993;90:4538–4542. [PMC free article: PMC46547] [PubMed: 8389454]
  641. Keating M.T., Williams L.T. Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells. Science. 1988;239:914–916. [PubMed: 2829358]
  642. Kelly K., Cochran B.H., Stiles C.D., Leder P. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell. 1983;35:603–610. [PubMed: 6606489]
  643. Kelly K., Davis P., Mitsuya H., Irving S., Wright J., Grassmann R., Fleckenstein B., Wano Y., Greene W., Sienbenlist U. A high proportion of early response genes are constitutively activated in T cells by HTLV-I. Oncogene. 1992;7:1463–1470. [PubMed: 1630809]
  644. Kelly M., Holland C.A., Lung M.L., Chattopadhyay S.K., Lowy D.R., Hopkins N.H. Nucleotide sequence of the 3′ end of MCF 247 murine leukemia virus. J. Virol. 1983;45:291–298. [PMC free article: PMC256411] [PubMed: 6296437]
  645. Kennison J.A. Transcriptional activation of Drosophila homeotic genes from distant regulatory elements. Trends Genet. 1993;9:75–79. [PubMed: 8098166]
  646. Kent M.L., Dawe S.C. Further evidence for a viral etiology in plasmacytoid leukemia of chinook salmon Oncorhynchus tshawytscha. Dis. Aquat. Org. 1993;15:115–121.
  647. Kertayadnya G., Wilcox G.E., Soeharsono S., Hartaningsih N., Coelen R.J., Cook R.D., Collins M.E., Brownlie J. Characteristics of a retrovirus associated with Jembrana disease in Bali cattle. J. Gen. Virol. 1993;74:1765–1778. [PubMed: 7690840]
  648. Keshet E., Temin H.M. Cell killing by spleen necrosis virus is correlated with a transient accumulation of spleen necrosis virus DNA. J. Virol. 1979;31:376–388. [PMC free article: PMC353460] [PubMed: 225560]
  649. Kettmann R., Cleuter Y., Gregoire D., Burny A. Role of the 3′ long open reading frame region of bovine leukemia virus in the maintenance of cell transformation. J. Virol. 1985;54:899–901. [PMC free article: PMC254885] [PubMed: 2987544]
  650. Kettmann R., Deschamps J., Cleuter Y., Portetelle D., Mammerickx M., Burny A. Leukogenesis by bovine leukemia virus: Provirus DNA integration and lack of RNA expression of viral long terminal repeat and 3′ proximate cellular sequences. Proc. Natl. Acad. Sci. 1982;79:2465–2469. [PMC free article: PMC346219] [PubMed: 6283527]
  651. Kettmann R., Deschamps J., Couez D., Claustriaux J.-J., Palm R., Burny A. Chromosome integration domain for bovine leukemia provirus in tumors. J. Virol. 1983;47:146–150. [PMC free article: PMC255216] [PubMed: 6306270]
  652. Kettmann R., Burny A., Callebaut I., Droogmans L., Mammerickx M., Willems L., Portetelle D. 1994Bovine leukemia virus In The retroviridae (ed. J.A. Levy), vol. 3, pp. 39–82. Plenum Press, New York. [PMC free article: PMC45265]
  653. Kettmann R., Cleuter Y., Mammerickx M., Meunier-Rotival M., Bernardi G., Burny A., Chantrenne H. Genomic integration of bovine leukemia provirus: Comparison between persistent lymphocytosis and lymph node tumor form of enzootic bovine leukosis. Proc. Natl. Acad. Sci. 1980;77:2577–2581. [PMC free article: PMC349445] [PubMed: 6248854]
  654. Kettmann R., Portetelle D., Mammerickx M., Cleuter Y., Dekegel D., Galoux M., Ghysdael J., Burny A., Chantrenne H. Bovine leukemia virus: An exogenous RNA oncogenic virus. Proc. Natl. Acad. Sci. 1976;73:1014–1018. [PMC free article: PMC430190] [PubMed: 57616]
  655. Khan A.S., Rowe W.P., Martin M.A. Cloning of endogenous murine leukemia virus-related sequences from chromosomal DNA of BALB/c and AKR/J mice: Identification of the env progenitor of AKR-247 mink cell focus-forming proviral DNA. J. Virol. 1982;44:625–636. [PMC free article: PMC256306] [PubMed: 6292522]
  656. Khan K.N., Kociba G.J., Wellman M.L. Macrophage tropism of feline leukemia virus (FeLV) of subgroup-C and increased production of tumor necrosis factor-alpha by FeLV-infected macrophages. Blood. 1993;81:2585–2590. [PubMed: 8387834]
  657. Khan W.N., Alt F.W., Gerstein R.M., Malynn B.A., Larsson I., Rathbun G., Davidson L., Muller S., Kantor A.B., Herzenberg L.A., Rosen F.S., Sideras P. Defective B cell development and function in BTK-deficient mice. Immunity. 1995;3:283–299. [PubMed: 7552994]
  658. Kim C.H., Casey J.W. Genomic variation and segregation of equine infectious anemia virus during acute infection. J. Virol. 1992;66:3879–3882. [PMC free article: PMC241174] [PubMed: 1316487]
  659. Kim C.H., Casey J.W. In vivo replicative status and envelope heterogeneity of equine infectious anemia virus in an inapparent carrier. J. Virol. 1994;68:2777–2780. [PMC free article: PMC236760] [PubMed: 8139056]
  660. Kim W.K., Tang Y., Kenny J., Longo D.L., Morse H.C. In murine AIDS, B cells are early targets of defective virus and are required for efficient infection and expression of defective virus in T cells and macrophages. J. Virol. 1994;68:6767–6769. [PMC free article: PMC237100] [PubMed: 8084011]
  661. Kimata J.T., Ratner L. Temporal regulation of viral and cellular gene expression during human T-lymphotropic virus type-I-mediated lymphocyte immortalization. J. Virol. 1991;65:4398–4407. [PMC free article: PMC248879] [PubMed: 2072456]
  662. Kimata J.T., Wong F.H., Wang J.J., Ratner L. Construction and characterization of infectious human T-cell leukemia virus type I molecular clones. Virology. 1994;204:656–664. [PubMed: 7941334]
  663. King W., Patel M.D., Lobel L.I., Goff S.P. Insertional mutagenesis of embryonal carcinoma cells by retroviruses. Science. 1985;228:901–904. [PubMed: 3838595]
  664. Kinoshita K., Hino S., Amagasaki T., Yamada Y., Suzuyama J., Momita S., Toriya K., Kamihira S., Ichimura M. Demonstration of adult T-cell leukemia virus antigen in milk from three seropositive mothers. Gann. 1984;73:103–105. [PubMed: 6329875]
  665. Kinoshita K., Amagasaki T., Ikeda S., Suzuyama J., Toriya K., Nishino K., Tagawa M., Ichimaru M., Kamihira S., Yamada Y., Momita S., Kusane M., Morikawa T., Fujita S., Ueda Y., Ito N., Yoshida M. Preleukemic state of adult T cell leukemia: Abnormal T lymphocytosis induced by human adult T cell leukemia-lymphoma virus. Blood. 1985;66:120–127. [PubMed: 2988665]
  666. Kinoshita T., Tsujimoto A., Shimotohno K. Sequence variations in LTR and env regions of HTLV-I do not discriminate between the virus from patients with HTLV-I-associated myelopathy and adult T-cell leukemia. Int. J. Cancer. 1991;47:491–495. [PubMed: 1995478]
  667. Kinoshita T., Shimoyama M., Tobinai M., Ito M., Ito S.-I., Ikeda S., Tajima K., Shimotohno K., Sugimura T. Detection of mRNA for the tax/rex1 gene of human T-cell leukemia virus type-I in the fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction. Proc. Natl. Acad. Sci. 1989;86:5620–5624. [PMC free article: PMC297674] [PubMed: 2787512]
  668. Kira J., Koyanagi Y., Yamada T., Itoyama Y., Goto I., Yamamoto N., Sasaki H., Sakaki Y. Increased HTLV-I proviral DNA in HTLV-I-associated myelopathy: A quantitative polymerase reaction study. Ann. Neurol. 1991;29:194–201. [PubMed: 2012389]
  669. Kirchgessner C.U., Patil C.K., Evans J.W., Cuomo C.A., Fried L.M., Carter T., Oettinger M.A., Brown J.M. DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science. 1995;267:1178–1183. [PubMed: 7855601]
  670. Kirsten W.H., Meyer L.A. Morphologic responses to a murine erythroblastosis virus. J. Natl. Cancer Inst. 1967;39:311–335. [PubMed: 18623947]
  671. Klein G. Role of EBV and Ig/myc translocation in Burkitt's lymphoma. Antibiot. Chemother. 1994;46:110–116. [PubMed: 7826031]
  672. Klempnauer K.-H., Gonda T.J., Bishop J.M. Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogene. Cell. 1982;31:453–463. [PubMed: 6297766]
  673. Klemsz M.J., McKercher S.R., Celada A., Van Beveren C., Maki R.A. The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene. Cell. 1990;61:113–124. [PubMed: 2180582]
  674. Klevjer-Anderson P., McGuire T.C. Neutralizing antibody response of rabbits and goats to caprine arthritis encephalitis virus. Infect. Immun. 1982;38:455–461. [PMC free article: PMC347761] [PubMed: 6292102]
  675. Klinken S.P., Fredrickson T.N., Hartley J.W., Yetter R.A., Morse H.C. III. Evolution of B cell lineage lymphomas in mice with a retrovirus-induced immunodeficiency syndrome, MAIDS. J. Immunol. 1988;140:1123–1131. [PubMed: 2830334]
  676. Klinman D.M., Morse H.C. III. Characteristics of B cell proliferation and activation in murine AIDS. J. Immunol. 1989;142:1144–1149. [PubMed: 2464640]
  677. Kmiecik T.E., Shalloway D. Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation. Cell. 1987;49:65–73. [PubMed: 3103925]
  678. Knight A.M., Harrison G.B., Pease R.J., Robinson P.J., Dyson P.J. Biochemical analysis of the mouse mammary tumor virus long terminal repeat product: Evidence for the molecular structure of an endogenous superantigen. Eur. J. Immunol. 1992;22:879–882. [PMC free article: PMC7163594] [PubMed: 1312476]
  679. Knight J., Zenke M., Disela C., Kowenz E., Vogt P., Engel J.D., Hayman M.J., Beug H. Temperature sensitive v-sea transformed erythroblasts: A model system to study gene expression during erythroid differentiation. Genes Dev. 1988;2:247–258. [PubMed: 3360325]
  680. Knowles D. Jr., Cheevers W., McGuire T., Stem T., Gorham J. Severity of arthritis is predicted by antibody response to gp135 in chronic infection with caprine arthritis-encephalitis virus. J. Virol. 1990;64:2396–2398. [PMC free article: PMC249403] [PubMed: 2325206]
  681. Knudson B.S., Feller S.M., Hanafusa H. Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk. J. Biol. Chem. 1994;269:32781–32787. [PubMed: 7806500]
  682. Koch S., Muralidhar G., Swain S.L. Both naive and memory CD4 T cell subsets become anergic during MAIDS and each subset can sustain disease. J. Immunol. 1994;152:5548–5556. [PubMed: 7910621]
  683. Koehne C.F., Lazo P.A., Alves K., Lee J.S., Tsichlis P.N., O'Donnell P.V. The Mlvi-1 locus involved in the induction of rat T-cell lymphomas and the pvt-1/Mis-1 locus are identical. J. Virol. 1989;63:2366–2369. [PMC free article: PMC250659] [PubMed: 2704080]
  684. Koenig S., Gendelman H.E., Orenstein J.M., Dal Canto M.C., Pezeshkpour G.H., Yungbluth M., Janotta F., Aksamit A., Martin M.A., Fauci A.S. Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science. 1986;233:1089–1093. [PubMed: 3016903]
  685. Komurian F., Pelloquin F., de Thé G. In vivo genomic variability of human T-cell leukemia virus type I depends more upon geography than upon pathologies. J. Virol. 1991;65:3770–3778. [PMC free article: PMC241407] [PubMed: 2041093]
  686. Kondo T., Kono H., Nonaka H., Miyamoto N., Yoshida R., Bando F., Inoue H., Miyoshi I., Hinuma Y., Hanaoka M. Risk of adult T-cell leukaemia lymphoma in HTLV-I carriers. Lancet. 1987;II:159. [PubMed: 2885620]
  687. Kongsuwan K., Allen J., Adams J.M. Expression of Hox2.4 homeobox gene directed by proviral insertion in a myeloid leukemia. Nucleic Acids Res. 1989;17:1881–1892. [PMC free article: PMC317530] [PubMed: 2564662]
  688. Kono T., Doi T., Yamada G., Hatakeyama M., Minamoto S., Tsudo M., Miyasaka M., Miyata T., Taniguchi T. Murine interleukin 2 receptor β chain: Dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertion. Proc. Natl. Acad. Sci. 1990;87:1806–1810. [PMC free article: PMC53572] [PubMed: 2155425]
  689. Kono Y., Kobayashi K., Fukunaga Y. Serological comparison among various strains of equine infectious anemia virus. Arch. Gesamte Virusforsch. 1971;34:202–208. [PubMed: 4330134]
  690. Kono Y., Hirasawa K., Fukunaga Y., Taniguchi T. Recrudescence of equine infectious anemia by treatment with immunosuppressive drugs. Natl. Inst. Anim. Health Q. 1976;16:8–15. [PubMed: 177894]
  691. Koralnik I.J., Boeri E., Saxinger W.C., Monico A.L., Fullen J., Gessain A., Guo H.-G., Gallo R.C., Markham P., Kalyanaraman A., Hirsch V., Allan J., Murthy K., Alford P., Slattery J.P., O'Brien S.J., Franchini G. Phylogenetic associations of human and simian T-cell leukemia/lymphotropic virus type I strains: Evidence for interspecies transmission. J. Virol. 1994;68:2693–2707. [PMC free article: PMC236747] [PubMed: 7908063]
  692. Korber B., Okayama A., Donnelly R., Tachibana N., Essex M. Polymerase chain reaction analysis of defective human T-cell leukemia virus type I proviral genomes in leukemic cells of patients with adult T-cell leukemia. J. Virol. 1991;65:5471–5476. [PMC free article: PMC249039] [PubMed: 1895396]
  693. Kordon E.C., Smith G.H., Callahan R., Gallahan D. A novel non-mouse mammary tumor virus activation of the Int3 gene in a spontaneous mouse mammary tumor. J. Virol. 1995;69:8066–8069. [PMC free article: PMC189755] [PubMed: 7494323]
  694. Korman A.J., Bourgarel P., Meo T., Rieckhof G.E. The mouse mammary tumor virus long terminal repeat encodes a type II transmembrane glycoprotein. EMBO J. 1992;11:1901–1905. [PMC free article: PMC556648] [PubMed: 1316276]
  695. Kost T.A., Koury M.J., Krantz S.B. Mature erythroid burst forming units are target cells for Friend virus-induced erythroid bursts. Virology. 1981;108:309–317. [PubMed: 6936971]
  696. Kost T.A., Koury M.J., Hankins W.E., Krantz S.B. Target cells for Friend virus-induced erythroid bursts in vivo. Cell. 1979;18:145–152. [PubMed: 509518]
  697. Kozak S.L., Hoatlin M.E., Ferro F.E. Jr., Majumdar M.K., Geib R.W., Kabat D. A Friend virus mutant that overcomes Fv-2rr resistance encodes a small glycoprotein that dimerizes, is processed to cell surfaces, and specifically activates erythropoietin receptors. J. Virol. 1993;67:2611–2620. [PMC free article: PMC237582] [PubMed: 8474164]
  698. Kraut N., Frampton J., McNargey K.M., Graf T. A functional Ets DNA binding domain is required to maintain multipotency of hematopoietic progenitors transformed by Myb-Ets. Genes Dev. 1994;8:33–44. [PubMed: 8288126]
  699. Krengel U., Schlichting L., Scherer A., Schumann R., Frech M., John J., Kabsch W., Pai E.F., Wittinghofer A. Three-dimensional structures of H-Ras p21 mutants: Molecular basis for their inability to function as signal switch molecules. Cell. 1990;62:539–548. [PubMed: 2199064]
  700. Kretzner L., Blackwood E.M., Eisenman R.N. Myc and Max proteins possess distinct transcriptional activities. Nature. 1992;359:426–429. [PubMed: 1406956]
  701. Kristal B.S., Reinhart T.A., Hoover E.A., Mullins J.I. Interference with superinfection and with cell killing and determination of host range and growth kinetics mediated by feline leukemia virus surface glycoproteins. J. Virol. 1993;67:4142–4153. [PMC free article: PMC237783] [PubMed: 8389921]
  702. Kruijer W., Cooper J.A., Hunter T., Verma I.M. PDGF induces rapid but transient expression of the v-fos gene. Nature. 1984;312:711–716. [PubMed: 6514007]
  703. Kubo Y., Nakagawa Y., Kakimi K., Matsui H., Iwashiro M., Kuribayashi K., Masuda T., Hiai H., Hirama T., Yanagawa S., Ishimoto A. Presence of transplantable T-lymphoid cells in C57BL/6 mice infected with murine AIDS virus. J. Virol. 1992;66:5691–5695. [PMC free article: PMC289140] [PubMed: 1323720]
  704. Kung H.J., Boerkoel C., Carter T.H. Retroviral mutagenesis of cellular oncogenes: A review with insights into the mechanisms of insertional activation. Curr. Top. Microbiol. Immunol. 1991;171:1–25. [PubMed: 1814689]
  705. Kushida S., Mizusawa H., Matsumura M., Tanaka H., Ami Y., Hori M., Yagami K.-I., Kameyama T., Tanaka Y., Yoshida A., Nyunoya H., Shimotohno K., Iwasaki Y., Uchida K., Miwa M. High incidence of HAM/TSP-like symptoms after administration of human T-cell leukemia virus type-I producing cells. J. Virol. 1994;68:7221–7226. [PMC free article: PMC237161] [PubMed: 7933104]
  706. Lagarias D.M., Radke K. Transcriptional activation of bovine leukemia virus in blood cells from experimentally infected asymptomatic sheep with latent infections. J. Virol. 1989;63:2099–2107. [PMC free article: PMC250626] [PubMed: 2539506]
  707. Lairmore M.D., Rosadio R.H., DeMartini J.C. Ovine lentivirus lymphoid interstitial pneumonia: Rapid induction in neonatal lambs. Am. J. Pathol. 1986;125:173–181. [PMC free article: PMC1888440] [PubMed: 3022591]
  708. Lairmore M.D., Akita G.Y., Russell H.I., DeMartini J.C. Replication and cytopathic effects of ovine lentivirus strains in alveolar macrophages correlate with in vivo pathogenicity. J. Virol. 1987;61:4038–4042. [PMC free article: PMC256029] [PubMed: 2824834]
  709. Lairmore M.D., Poulson J.M., Adducci T.A., DeMartini J.C. Lentivirus-induced lymphoproliferative disease: Comparative pathogenicity of phenotypically distinct ovine lentivirus strains. Am. J. Pathol. 1988;130:80–90. [PMC free article: PMC1880540] [PubMed: 3337213]
  710. Lairmore M.D., Jacobson S., Garcia F., De B.K., Castillo L., Larreategui M., Roberts B.D., Levine P.H., Blattner W.A., Kaplan J.E. Isolation of human T-cell lymphotropic virus type 2 from Guaymi Indians in Panama. Proc. Natl. Acad. Sci. 1990;87:1175–1184. [PMC free article: PMC55055] [PubMed: 2247455]
  711. Lammie G.A., Smith R., Silver J., Brookes S., Dickson C., Peters G. Proviral insertions near cyclin D1 in mouse lymphomas: A parallel for BCL1 translocations in human B-cell neoplasms. Oncogene. 1992;7:2381–2387. [PubMed: 1461646]
  712. Land H., Parada L.F., Weinberg R.A. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. 1983;304:596–602. [PubMed: 6308472]
  713. Land H., Chen A.C., Morgenstern J.P., Parada L.F., Weinberg R.A. Behaviour of myc and ras oncogenes in transformation of rat embryo fibroblasts. Mol. Cell. Biol. 1986;6:1917–1925. [PMC free article: PMC367729] [PubMed: 3785184]
  714. Lane T., Ibanez C., Garcia A., Graf T., Lipsick J. Transformation by v-myb correlates with trans-activation of gene expression. Mol. Cell. Biol. 1990;10:2591–2598. [PMC free article: PMC360617] [PubMed: 2160580]
  715. Langdon W.Y., Hartley J.W., Klinken S.P., Ruscetti S.K., Morse H.C. III. v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas. Proc. Natl. Acad. Sci. 1989;86:1168–1172. [PMC free article: PMC286647] [PubMed: 2784003]
  716. Largaespada D.A., Shaughnessy J.D. Jr., Jenkins N.A., Copeland N.G. Retroviral integration at the Evi2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels. J. Virol. 1995;69:5095–5102. [PMC free article: PMC189327] [PubMed: 7609078]
  717. Latarjet R., Duplan J.F. Experiments and discussion on leukaemogenesis by cell-free extracts of radiation-induced leukemia in mice. Int. J. Radiat. Biol. 1962;5:339–344. [PubMed: 14462662]
  718. Lavigueur A., Bernstein A. P53 transgenic mice: Accelerated erythroleukemia induction by Friend virus. Oncogene. 1991;6:2197–2201. [PubMed: 1766668]
  719. Lavu S., Premkumar R. Structural organization and nucleotide sequence of mouse c-myb oncogene: Activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5′ coding sequences. Nucleic Acids Res. 1986;14:5309–5320. [PMC free article: PMC311542] [PubMed: 3016644]
  720. Lavu S., Reddy E.P. Structural organization and nucleotide sequence of mouse c-myb: Activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5′ coding sequences. Nucleic Acids Res. 1986;14:5309–5320. [PMC free article: PMC311542] [PubMed: 3016644]
  721. Lax I., Kris R., Samson I., Ullrich A., Hayman M.J., Beug H., Schlessinger J. Activation of c-erbB in avian leukosis virus-induced erythroblastosis leads to the expression of a truncated EGF receptor kinase. EMBO J. 1985;4:3179–3182. [PMC free article: PMC554639] [PubMed: 3004938]
  722. Lax I., Johnson A., Howk R., Sap J., Bellot F., Winkler M., Ullrich A., Vennstrom B., Schlessinger J., Givol D. Chicken epidermal growth factor (EGF) receptor: cDNA cloning, expression in mouse cells, and differential bindings of EGF and transforming growth factor alpha. Mol. Cell. Biol. 1988;8:1970–1978. [PMC free article: PMC363375] [PubMed: 3260329]
  723. Lazo P.A., Tsichlis P.N. Recombination between two integrated proviruses, one of which was inserted near c-myc in a retrovirus-induced rat thymoma: Implications for tumor progression. J. Virol. 1988;62:788–794. [PMC free article: PMC253633] [PubMed: 3276924]
  724. Lazo P.A., Lee J.S., Tsichlis P.N. Long-distance activation of the Myc protooncogene by provirus insertion in Mlvi1 or Mlvi4 in rat T-cell lymphomas. Proc. Natl. Acad. Sci. 1990;87:170–173. [PMC free article: PMC53222] [PubMed: 1688653]
  725. Leal F., Williams L.T., Robbins K.C., Aaronson S.A. Evidence that the v-sis gene product transforms by interaction with the receptor for platelet-derived growth factor. Science. 1985;230:327–330. [PubMed: 2996133]
  726. Lee F.S., Lane T.F., Kuo A., Shackleford G.M., Leder P. Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int2/Fgf3 transgenic mice. Proc. Natl. Acad. Sci. 1995;92:2268–2272. [PMC free article: PMC42465] [PubMed: 7892260]
  727. Lee J.M., Bernstein A. Apoptosis, cancer and the p53 tumour suppressor gene. Cancer Metastasis Rev. 1995;14:149–161. [PubMed: 7554031]
  728. Lee T.H., Coligan J.E., Sodroski J.G., Haseltine W.A., Salahuddin S.Z., Wong-Staal F., Gallo R.C. Antigens encoded by the 3′-terminal region of human T-cell leukemia virus: Evidence for a functional gene. Science. 1984;226:57–61. [PubMed: 6089350]
  729. Leevers S.J., Paterson H.F., Marshall C.J. Requirement of Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature. 1994;369:411–414. [PubMed: 8196769]
  730. Legrand E., Dalculsi R., Duplan J.F. Characteristics of the cell populations involved in extrathymic lymphosarcoma induced in C57BL/6 mice by RadLV-Rs. Leuk. Res. 1981;5:223–233. [PubMed: 7022032]
  731. Lehky T.J., Fox C.H., Koenig S., Levin M.C., Flerlage N., Izumo S., Sato E., Raine C.S., Osame M., Jacobson S. Detection of human T-lymphotropic virus type I (HTLV-I) tax RNA in the central nervous system of HTLV-I-associated myelopathy/tropical spastic paraparesis patients by in situ hybridization (comments). Ann. Neurol. 1995;37:167–175. [PubMed: 7847858]
  732. Leibovitch S.A., Guillier M., Lenormand J.L., Leibovitch M.P. Accumulation of the c-mos protein is correlated with postnatal development of skeletal muscle. Oncogene. 1991;6:1617–1622. [PubMed: 1833718]
  733. Lemay G., Jolicoeur P. Rearrangement of a DNA sequence homologous to a cell-virus junction fragment in several Moloney murine leukemia virus-induced rat thymomas. Proc. Natl. Acad. Sci. 1984;81:38–42. [PMC free article: PMC344605] [PubMed: 6607472]
  734. Lenz J., Haseltine W.A. Localization of the leukemogenic determinants of SL3-3, an ecotropic, XC-positive murine leukemia virus of AKR origin. J. Virol. 1983;47:317–328. [PMC free article: PMC255263] [PubMed: 6312068]
  735. Lenz J., Celander D., Crowther R.L., Patarca R., Perking D.W., Haseltine W.A. Determination of the leukaemogenicity of a murine retrovirus by sequences within the long terminal repeat. Nature. 1984;308:467–470. [PubMed: 6323995]
  736. Leslie K.B., Lee F., Schrader J.W. Intracisternal A-type particle-mediated activations of cytokine genes in a murine myelomonocytic leukemia: Generation of functional cytokine mRNAs by retroviral splicing events. Mol. Cell. Biol. 1991;11:5562–5570. [PMC free article: PMC361926] [PubMed: 1922064]
  737. Leung K., Nabel G.J. HTLV-I trans-activator induces interleukin-2 receptor expression through an NFMB-like factor. Nature. 1988;333:776–778. [PubMed: 2838755]
  738. Levesque K.S., Bonham L., Levy L.S. flvi1, a common integration domain of feline leukemia virus in naturally occurring lymphomas of a particular type. J. Virol. 1990;64:3455–3462. [PMC free article: PMC249607] [PubMed: 2161948]
  739. Levine A.J. The tumor suppressor genes. Annu. Rev. Biochem. 1993;62:623–651. [PubMed: 8394683]
  740. Levy L.S., Lobelle-Rich P.A. Insertional mutagenesis of flvi2 in tumors induced by infection with LC-FeLV, a myc-containing strain of feline leukemia virus. J. Virol. 1992;66:2885–2892. [PMC free article: PMC241047] [PubMed: 1313907]
  741. Levy L.S., Gardner M.B., Casey J.W. Isolation of a feline leukaemia provirus containing the oncogene myc from a feline lymphosarcoma. Nature. 1984;308:853–856. [PubMed: 6325921]
  742. Levy L.S., Lobelle-Rich P.A., Overbaugh J. flvi2, a target of retroviral insertional mutagenesis in feline thymic lymphosarcomas, encodes bmi-1. Oncogene. 1993a;8:1833–1838. [PubMed: 8390036]
  743. Levy L.S., Lobelle-Rich P.A., Overbaugh J., Abkowitz J.L., Fulton R. Coincident involvement of flvi2, c-myc, and novel env genes in natural and experimental lymphosarcomas induced by feline leukemia virus. Virology. 1993b;196:892–895. [PubMed: 8396818]
  744. Li J., Vogt P.K. The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head. Proc. Natl. Acad. Sci. 1993;90:4490–4494. [PMC free article: PMC46537] [PubMed: 8099441]
  745. Li J.P., Baltimore D. Mechanism of leukemogenesis induced by mink cell focus-forming murine leukemia viruses. J. Virol. 1991;65:2408–2414. [PMC free article: PMC240593] [PubMed: 1850020]
  746. Li J.P., D'Andrea A.D., Lodish H.F., Baltimore D. Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor. Nature. 1990;343:762–764. [PubMed: 2154701]
  747. Li J.P., Hu H.O., Niu Q.T., Fang C. Cell surface activation of the erythropoietin receptor by Friend spleen focus-forming virus gp55. J. Virol. 1995;69:1714–1719. [PMC free article: PMC188774] [PubMed: 7853508]
  748. Li N., Batzer A., Daly R., Yajnik. E. Skolink V., Chardin P., Bar-Sagi D., Margolis B., Schlessinger J. Guanine nucleotide releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinase to Ras signaling. Nature. 1993;363:85–88. [PubMed: 8479541]
  749. Li Q.X., Fan H. Bone marrow depletion by 89Sr complements a preleukemic defect in a long terminal repeat variant of Moloney leukemia virus. J. Virol. 1991a;65:4442–4448. [PMC free article: PMC248884] [PubMed: 1649340]
  750. Li Q.X., Fan H. Combined infection by Moloney murine leukemia virus and mink cell focus-forming virus recombinant induced cytopathic effects in fibroblasts of long-term cultures from preleukemic mice. J. Virol. 1991b;64:3701–3711. [PMC free article: PMC249664] [PubMed: 2164592]
  751. Li Y., Golemia E., Hartley J.W., Hopkins N. Disease specificity of nondefective Friend and Moloney murine leukemia viruses is controlled by a small number of nucleotides. J. Virol. 1987;61:693–700. [PMC free article: PMC254008] [PubMed: 3468264]
  752. Li Y., Holland C.A., Hartley J.W., Hopkins N. Viral integration near c-myc in 10-20% of MCF 247-induced AKR lymphomas. Proc. Natl. Acad. Sci. 1984;81:6808–6811. [PMC free article: PMC392021] [PubMed: 6093121]
  753. Liao X., Buchberg A.M., Jenkins N.A., Copeland N.G. Evi-5, a common site of retroviral integration in AKXD T-cell lymphomas, maps near Gfi-1 on mouse chromosome 5. J. Virol. 1995;69:7132–7137. [PMC free article: PMC189633] [PubMed: 7474133]
  754. Liberski P.P., Rodgers-Johnson P., Char G., Piccardo P., Gibbs C.J. Jr., Gajdusek D.C. HTLV-I-like viral particles in spinal cord cells in Jamaican tropical spastic paraparesis. Ann. Neurol. 1988;23 (suppl.):S185–S187. [PubMed: 2831798]
  755. Lieberman M., Kaplan H.S. Leukemogenic activity of filtrates from radiation-induced lymphoid tumors of mice. Science. 1959;130:387–388. [PubMed: 13675761]
  756. Lilly F. Susceptibility to two strains of Friend leukemia virus in mice. Science. 1967;155:461–462. [PubMed: 6015694]
  757. Lilly F. Fv2: Identification and location of a second gene governing the spleen focus response to Friend leukemia virus in mice. J. Natl. Cancer Inst. 1970;45:163–169. [PubMed: 5449211]
  758. Lilly F., Duran-Reynals M.L., Rowe W.P. Correlation of early murine leukemic virus titer and H-2 type with spontaneous leukemia in mice of the BALB/c x AKR cross: A genetic analysis. J. Exp. Med. 1975;141:882–889. [PMC free article: PMC2189752] [PubMed: 165256]
  759. Linial M., Groudine M. Transcription of three c-myc exons is enhanced in chicken bursal lymphoma cell lines. Proc. Natl. Acad. Sci. 1985;82:53–57. [PMC free article: PMC396969] [PubMed: 3855549]
  760. Liscovitch M., Cantley L.C. Signal transduction and membrane traffic: The PITP/phosphoinositide connection. Cell. 1995;81:659–662. [PubMed: 7774006]
  761. Liu X., Pawson T. Biochemistry of the Src protein tyrosine kinase: Regulation by SH2 and SH3 domains. Recent Prog. Horm. Res. 1994;49:149–160. [PubMed: 7511826]
  762. Loar A.S. Feline leukemia virus: Immunization and prevention. Vet. Clin. North Am. Small Anim. Pract. 1993;23:193–211. [PubMed: 8380657]
  763. Loliger H.C. Experimentelle untersuchungen zur ubertragung der geflugelleukose. II. Serienubertragungen mit einem myelostramm. III. Vergleichende unter suchungen zwischen zwei aus spontanfallen isolierten myelostammen und einem lymphoma-tosestamm. Dtsch. Tierarztl. Wochenschr. 1964;71:207–212. [PubMed: 5889441]
  764. Lonai P., Haran-Ghera N. Resistance genes to murine leukemia in the I immune response gene region of the H-2 complex. J. Exp. Med. 1977;141:882–889. [PMC free article: PMC2180826] [PubMed: 197197]
  765. Longmore G.D., Lodish H.F. An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine superfamily oncogene. Cell. 1991;67:1089–1102. [PubMed: 1662116]
  766. Lowenstein E.J., Daly R.J., Batzer A.G., Li W., Margolis B., Lammers R., Ullrich A., Skolnik E.Y., Bar-Sagi D., Schlessinger J. The SH2 and SH3-containing protein Grb2 links receptor tyrosine kinase to Ras signaling. Cell. 1992;70:431–442. [PubMed: 1322798]
  767. Lu S.J., Rowan S., Bani M.R., Ben-David Y. Retroviral integration within the Fli2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: Evidence that NF-E2 is essential for globin expression. Proc. Natl. Acad. Sci. 1994;91:8398–8402. [PMC free article: PMC44613] [PubMed: 8078893]
  768. Lung M.L., Hartley J.W., Rowe W.P., Hopkins N.H. Large RNase T1-resistant oligonucleotides encoding p15E and the U3 region of the long terminal repeat distinguish two biological classes of mink cell focus-forming type C viruses of inbred mice. J. Virol. 1983;45:275–290. [PMC free article: PMC256410] [PubMed: 6296436]
  769. Lunger P.D., Hardy W.D. Jr., Clark H.F. C-type particles in a reptilian tumor. J. Natl. Cancer Inst. 1974;52:1231–1235. [PubMed: 4363706]
  770. Luscher B.E., Christenson E., Litchfield D.W. Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation. Nature. 1990;344:517–522. [PubMed: 2157164]
  771. Lynch W.P., Portis J.L. Murine retrovirus-induced spongiform encephalopathy: Disease expression is dependent on postnatal development of the central nervous system. J. Virol. 1993;67:2601–2610. [PMC free article: PMC237581] [PubMed: 8386268]
  772. Lynch W.P., Robertson S.J., Portis J.L. Induction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia. J. Virol. 1995;69:1408–1419. [PMC free article: PMC188727] [PubMed: 7853473]
  773. Lynch W.P., Czub S., McAtee F.J., Hayes S.F., Portis J.L. Murine retrovirus-induced spongiform encephalopathy: Productive infection of microglia and cerebellar neurons in accelerated CNS disease. Neuron. 1991;7:365–379. [PubMed: 1654946]
  774. MacArthur C.A., Shankar D.B., Shackleford G.M. Fgf8, activated by proviral insertion, cooperates with the Wnt1 transgene in murine mammary tumorigenesis. J. Virol. 1995;69:2501–2507. [PMC free article: PMC188926] [PubMed: 7884899]
  775. MacAuley A., Pawson T. Cooperative transforming activities of ras, myc, and src viral oncogenes in nonestablished rat adrenocortical cells. J. Virol. 1988;62:4712–4721. [PMC free article: PMC253586] [PubMed: 2846881]
  776. MacDonald M.E., Mak T.W., Bernstein A. Erythroleukemia induction by replication-competent type C viruses cloned from the anemia- and polycythemia-inducing isolates of Friend leukemia virus. J. Exp. Med. 1980;151:1493–1503. [PMC free article: PMC2185877] [PubMed: 6247414]
  777. Mackey L., Jarrett W., Jarrett O., Laird H.M. Anemia associated with feline leukemia virus infection in cats. J. Natl. Cancer Inst. 1975;54:209–217. [PubMed: 163317]
  778. Maeda Y., Furukawa M., Takehara Y., Yoshimura K., Miyamoto K., Matsuura T., Morishima Y., Tajima K., Okochi K., Hinuma Y. Prevalence of possible adult T-cell leukemia virus-carriers among volunteer blood donors in Japan: A nationwide study. Int. J. Cancer. 1984;33:717–720. [PubMed: 6329964]
  779. Maekawa M., Li S., Iwamatsu A., Morishita T., Yokota K., Imai Y., Kohsaka S., Nakamura S., Hattori S. A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions. Mol. Cell. Biol. 1994;14:6879–6885. [PMC free article: PMC359218] [PubMed: 7935405]
  780. Magnuson N.S., Beck T., Vahidi H., Hahn H., Smola U., Rapp U.R. The Raf-1 serine/threonine kinase. Semin. Cancer Biol. 1995;5:247–253. [PubMed: 7803760]
  781. Mahieux R., de Thé G., Gessain A. The tax mutation at nucleotide 7959 of human T-cell leukemia virus type 1 (HTLV-1) is not associated with tropical spastic paraparesis/HTLV-1 associated myelopathy but is linked to the cosmopolitan molecular genotype. J. Virol. 1995;69:5925–5927. [PMC free article: PMC189477] [PubMed: 7637041]
  782. Maihle N.J., Kung H.-J. c-erbB and the epidermal growth-factor receptor: A molecule with dual identity. Biochim. Biophys. Acta. 1988;948:287–304. [PubMed: 2645940]
  783. Majumdar M.K., Cho C.-L., Fox M.T., Eckner K.L., Kozak S., Kabat D., Geib R.W. Mutations in the env gene of Friend spleen focus forming virus overcome Fv-2r-mediated resistance to Friend virus-induced erythroleukemia. J. Virol. 1992;66:3652–3660. [PMC free article: PMC241148] [PubMed: 1583724]
  784. Maki N., Miyazawa T., Fukasawa M., Hasegawa A., Hayami M., Miki K., Mikami T. Molecular characterization and heterogeneity of feline immunodeficiency virus isolates. Arch. Virol. 1992;123:29–45. [PubMed: 1312825]
  785. Maki T., Bos T.J., Davis C., Starbuck M., Vogt P.K. Avian sarcoma virus 17 carries the jun oncogene. Proc. Natl. Acad. Sci. 1987;84:2848–2852. [PMC free article: PMC304757] [PubMed: 3033666]
  786. Makino M., Morse H.C. III, Fredrickson T.N., Hartley J.W. H-2-associated and background gene influence the development of a murine retrovirus-induced immunodeficiency syndrome. J. Immunol. 1990;144:4347–4355. [PubMed: 2160500]
  787. Makris A., Patriotis C., Bear S.E., Tsichlis P.N. Genomic organization and expression of Tpl2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: Activation by provirus insertion. J. Virol. 1993a;67:4283–4289. [PMC free article: PMC237798] [PubMed: 8510223]
  788. Makris A., Patriotis C., Bear S.E., Tsichlis P.N. Structure of a Moloney murine leukemia virus-virus-like 30 recombinant: Implications for transduction of the c-Ha-ras proto-oncogene. J. Virol. 1993b;67:1286–1291. [PMC free article: PMC237495] [PubMed: 8437216]
  789. Malin G., Plachy J., Bumstead N., Hala K. Genetic analysis of four differing traits (MHC haplotype, tumor response, CD4:CD8 ratio, Ev17) in CB and CC congenic chickens. Exp. Clin. Immunogenet. 1993;10:152–160. [PubMed: 7904456]
  790. Malkin D. Germline p53 mutations and heritable cancer. Annu. Rev. Genet. 1994a;28:443–465. [PubMed: 7893135]
  791. Malkin D. P53 and the Li-Fraumeni syndrome. Biochim. Biophys. Acta. 1994b;1198:197–213. [PubMed: 7819275]
  792. Mammerickx M. La transmission verticale et horizontale de la leucose bovine enzootique. Premiers resultats apres cinq ans d'experimentation. Ann. Med. Vet. 1972;116:647–659.
  793. Mammerickx M., Palm R., Portelle D., Burny A. Experimental transmission of leukosis in sheep: Latency period of the tumoral disease. Leukemia. 1988;2:103–107. [PubMed: 2830439]
  794. Marchetti A., Buttitta F., Miyazaki S., Gallahan D., Smith G.H., Callahan R. Int6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasia. J. Virol. 1995;69:1932–1938. [PMC free article: PMC188811] [PubMed: 7853537]
  795. Marchetti A., Robbins J., Campbell G., Buttitta F., Squartini F., Bistocchi M., Callahan R. Host genetic background effect on the frequency of mouse mammary tumor virus-induced rearrangements of the int1 and int2 loci in mouse mammary tumors. J. Virol. 1991;65:4550–4554. [PMC free article: PMC248904] [PubMed: 1712864]
  796. Marcu K.B., A. Bossone S., J. Patel A. myc function and regulation. Annu. Rev. Biochem. 1992;61:809–860. [PubMed: 1497324]
  797. Marrack P., Kushnir E., Kappler J. A maternally inherited superantigen encoded by a mammary tumor virus. Nature. 1991;349:524–526. [PubMed: 1846947]
  798. Marrack P., Winslow G.M., Choi Y., Scherer M., Pullen A., White J., Kappler J.W. The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions. Immunol. Rev. 1993;131:79–92. [PubMed: 8387458]
  799. Marshall C.J. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr. Opin. Genet. Dev. 1994;4:82–89. [PubMed: 8193545]
  800. Marshall C.J. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell. 1995;80:179–186. [PubMed: 7834738]
  801. Marth J.D., Peet R., Krebs E.G., Perlmutter R.M. A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA. Cell. 1985;43:393–404. [PubMed: 2416464]
  802. Martin, Viskochil G.D., Bollag G., McCabe P.C., Crosier W.J., Haubruck H., Conroy L., Clark R., O'Connell P., Cawthorn R., Innis M.A., McCormick F. The Gap-related domain of the neurofibromatosis type 1 gene products interacts with Ras. Cell. 1990;63:843–849. [PubMed: 2121370]
  803. Martineau D., Bowser P.R., Renshaw R.R., Casey J.W. Molecular characterization of a unique retrovirus associated with a fish tumor. J. Virol. 1992;66:596–599. [PMC free article: PMC238323] [PubMed: 1727503]
  804. Martineau D., Bowser P.R., Wooster G.A., Armstrong L.D. Experimental transmission of a dermal sarcoma in fingerling walleyes (Stizostedion vitreum vitreum). Vet. Pathol. 1990;27:230–234. [PubMed: 2402851]
  805. Maruyama M., Shibuya H., Harada H., Hatakeyama M., Seiki M., Fujita T., Inoue J., Yoshida M., Taniguchi T. Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-I-encoded p40xl and T3/Ti complex triggering. Cell. 1987;48:343–350. [PubMed: 3026643]
  806. Marx M., Eychene A., Laugier D., Bechade C., Cristanti P., Dezelee P., Pessac B., Calothy G. A novel oncogene related to c-mil is transduced in chicken neuroretina cells induced to proliferate by infection with an avian lymphomatosis virus. EMBO J. 1988;7:3369–3374. [PMC free article: PMC454834] [PubMed: 2850163]
  807. Marx P.A., Maul D.H., Osborn K.G., Lerche N.W., Moody P., Lowenstine L.J., Henrickson R.V., Arthur L.O., Gilden R.V., Gravell M., London W.T., Sever J.L., Levy J.A., Munn R.J., Gardner M.B. Simian AIDS: Isolation of a type D retrovirus and transmission of the disease. Science. 1984;223:1083–1086. [PubMed: 6695196]
  808. Marx P.A., Osborn K.G., Maul D.H., Lerche N.W., Lowenstine L.J., Kluge J.D., Zaiss C.P., Henrickson R.V., Shiigi S.M., Wilson B.J., Malley A., Olson L.C., McNulty W.P., Arthur L.O., Gilden R.V., Barker C.S., Hunter E., Munn R.J., Heidecker G., Bryant M.L., Gardner M.B. Isolation of a new serotype of simian acquired immune deficiency syndrome type D retrovirus from Celebes black macaques (Macaca nigra) with immune deficiency and retroperitoneal fibromatosis. J. Virol. 1985;56:571–578. [PMC free article: PMC252614] [PubMed: 2997477]
  809. Massey A.C., Coppola M.A., Thomas C.Y. Origin of pathogenic determinants of recombinant murine leukemia viruses: Analysis of Bxv1-related xenotropic viruses from CWD mice. J. Virol. 1990;64:5491–5499. [PMC free article: PMC248601] [PubMed: 2170683]
  810. Matheise J.P., Delcommenne M., Mager A., Didembourg C.H., Letesson J.J. CD5+ B cells from bovine leukemia virus infected cows are activated cycling cells responsive to interleukin 2. Leukemia. 1992;6:304–309. [PubMed: 1375303]
  811. Matsuda M., Hoffman P.M., Ruscetti S.K. Viral determinants that control the neuropathogenicity of PVC-211 murine leukemia virus in vivo determine brain capillary endothelial cell tropism of the virus in vitro. J. Virol. 1993;67:4580–4587. [PMC free article: PMC237842] [PubMed: 8392599]
  812. Matsuda M., Mayer B.J., Fukui Y., Hanafusa H. Binding of transforming protein, p74 gag-crk , to a broad range of phosphotyrosine-containing proteins. Science. 1990;248:1537–1539. [PubMed: 1694307]
  813. Matsuoka M., Hagiya M., Hattori T., Asou N., Maeda S., Shimada K., Tsai S.C., Sakano H., Takatsuki K. Gene rearrangements of T cell receptor β and γ chains in HTLV-I infected primary neoplastic T cells. Leukemia. 1988;2:84–90. [PubMed: 2893862]
  814. Matsushime H., Wang L.H., Shibuya M. Human c-ROS1 gene homologous to the v-ros sequence of UR2 sarcoma virus encodes for a transmembrane receptor like molecule. Mol. Cell. Biol. 1986;6:3000–3004. [PMC free article: PMC367872] [PubMed: 3023956]
  815. Matthews E.A., Vasmel W.L.E., Schoenmakers H.J., Melief C.J.M. Retrovirally induced murine B-cell tumors rarely show proviral integration in sites common in T-cell tumors. Int. J. Cancer. 1989;43:1120–1125. [PubMed: 2543645]
  816. Maxwell S.A., Arlinghaus R.B. Serine kinase activity associated with Moloney murine sarcoma virus-124-encoded p37 mos . Virology. 1985;143:321–333. [PubMed: 2998008]
  817. Mayer A., Duran-Reynals M.L., Lilly F. Fv1 restriction of lymphoma development and of thymic ecotropic and xenotropic MuLV expression in mice of the AKR/J x RF/J cross. Cell. 1978;15:429–435. [PubMed: 214239]
  818. Mayer B.J., Hanafusa H. Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity. Proc. Natl. Acad. Sci. 1990a;87:2638–2642. [PMC free article: PMC53745] [PubMed: 1690891]
  819. Mayer B.J., Hanafusa H. Mutagenic analysis of the v-crk oncogene: requirement for SH2 and SH3 domains and correlation between increased cellular phosphotyrosine and transformation. J. Virol. 1990b;64:3581–3589. [PMC free article: PMC249650] [PubMed: 1695251]
  820. Mayer B.J., Hamaguchi M., Hanafusa H. A novel viral oncogene with structural similarity to phospholipase C. Nature. 1988;332:272–275. [PubMed: 2450282]
  821. McAtee F.J., Portis J.L. Monoclonal antibodies specific for wild mouse neurotropic retrovirus: Detection of comparable levels of virus replication in mouse strains susceptible and resistant to paralytic disease. J. Virol. 1985;56:1018–1022. [PMC free article: PMC252677] [PubMed: 3877818]
  822. McCormick F. Activators and effectors of Ras p21 protein. Curr. Opin. Genet. Dev. 1994;4:71–76. [PubMed: 8193543]
  823. McCormick F. Ras signaling and NF1. Curr. Opin. Genet. Dev. 1995;5:51–55. [PubMed: 7749326]
  824. McDonnell P.C., Kumar S., Rabson A.B., Gelinas C. Transcriptional activity of rel proteins. Oncogene. 1992;7:163–170. [PubMed: 1741161]
  825. McDonough S.K., Larsen S., Brodey R.S., Stock N.D., Hardy W.D. Jr. A transmissible feline fibrosarcoma of viral origin. Cancer Res. 1971;31:953–956. [PubMed: 4997847]
  826. McDougall A.S., Terry A., Tzavaras T., Cheney C., Rojko J., Neil J.C. Defective endogenous proviruses are expressed in feline lymphoid cells: Evidence for a role in natural resistance to subgroup B feline leukemia viruses. J. Virol. 1994;68:2151–2160. [PMC free article: PMC236690] [PubMed: 8138999]
  827. McGrath J.P., Capon D.J., Goeddel D.V., Levinson A.D. Comparative biochemical properties of the normal and activated human ras p21 protein. Nature. 1984;310:644–649. [PubMed: 6147754]
  828. McGuire T.C., Crawford T.B., Henson J.B. Immunofluorescent localization of equine infectious anemia virus in tissue. Am. J. Pathol. 1971;61:283–294. [PMC free article: PMC2047532] [PubMed: 4322275]
  829. McGuire T.C., Henson J.B., Burger D. Complement [C3]-coated red blood cells following infection with the virus of equine infectious anemia. J. Immunol. 1969a;103:293–299. [PubMed: 4184824]
  830. McGuire T.C., Henson J.B., Quist S.E. Viral induced hemolysis in equine infectious anemia. J. Am. Vet. Res. 1969b;30:2091–2097. [PubMed: 5389415]
  831. McGuire T.C., O'Rourke K.I., Knowles D.P., Cheevers W.P. Caprine arthritis encephalitis lentivirus transmission and disease. Curr. Top. Microbiol. Immunol. 1990;160:61–75. [PubMed: 2162288]
  832. McKhann G. II, Gibbs C.J. Jr., Mora C.A., Rodgers-Johnson P.E., Liberski P.P., Gdula W.J., Zaninovic V. Isolation and characterization of HTLV-I from symptomatic family members with tropical spastic paraparesis (HTLV-I encephalomyeloneuropathy). J. Infect. Dis. 1989;160:371–379. [PubMed: 2474617]
  833. McNab W.B., Jacobs R.M., Smith H.E. A serological survey for bovine immunodeficiencylike virus in Ontario dairy cattle and associations between test results, production records and management practices. Can. J. Vet. Res. 1994;58:36–41. [PMC free article: PMC1263657] [PubMed: 8143251]
  834. Meirom R., Brenner J., Trainin Z. BLV-infected lymphocytes exhibit two patterns of expression as determined by Ig and CD5 markers. Vet. Immunol. Immunopathol. 1993;36:179–186. [PubMed: 7682745]
  835. Merino F., Robert-Guroff M., Clark M., Biondo-Bracho M., Blattner W.A., Gallo R.C. Natural antibodies to human T-cell leukemia lymphoma virus in healthy Venezuelan populations. Int J. Cancer. 1984;34:501–506. [PubMed: 6092282]
  836. Meruelo D., Lieberman M., Ginzton N., Deak B., McDevitt H.O. Genetic control of radiation leukemia virus-induced tumorigenesis. I. Role of the major histocompatibility complex, H-2. J. Exp. Med. 1977;146:1079–1087. [PMC free article: PMC2180823] [PubMed: 197195]
  837. Metz T. Oncogenes and erythroid differentiation. Semin. Cancer Biol. 1994;5:125–135. [PubMed: 8061329]
  838. Metz T., Graf T. v-myb and v-ets transform chicken erythroid cells and cooperate both in trans and in cis to induce distinct differentiation phenotypes. Genes Dev. 1991a;5:369–380. [PubMed: 2001839]
  839. Metz T., Graf T. Fusion of the nuclear oncoproteins v-Myb and v-Ets is required for leukemogenicity of E26 virus. Cell. 1991b;66:95–105. [PubMed: 2070421]
  840. Meyerhans A., Cheynier R., Albert J., Seth M., Kwok S., Sninsky J., Morfeldt-Manson L., Asjo B., Wain-Hobson S. Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations. Cell. 1989;58:901–910. [PubMed: 2550139]
  841. Milburn M.V., Tong L., deVos A.M., Brunger A., Yamaizumi Z., Nishimura S., Kim S.H. Molecular switch for signal transduction: Structural differences between active and inactive forms of protooncogenic ras proteins. Science. 1990;247:939–945. [PubMed: 2406906]
  842. Miles B.D., Robinson H.L. High-frequency transduction of c-erbB in avian leukosis virus-induced erythroblastosis. J. Virol. 1985;54:295–303. [PMC free article: PMC254797] [PubMed: 2985798]
  843. Miller A., Curran T., Verma I. c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene. Cell. 1984;36:51–60. [PubMed: 6607118]
  844. Miller J., Miller L., Olson C., Gilette K. Virus-like particles in phytohemagglutinin-stimulated lymphocyte cultures with reference to bovine lymphosarcoma. J. Natl. Cancer Inst. 1969;43:1459–1462. [PubMed: 5408805]
  845. Minamoto G.Y., Gold J.W.M., Scheinberg D.A., Hardy W.D., Chien N., Zuckerman E., Reich L., Deitz K., Gee T., Hoffer J., Mayer K., Gabrilove J., Clarkson B., Armstrong D. Infection with human T-cell leukemia virus type-I in patients with leukemia. N. Engl. J. Med. 1988;318:219–222. [PubMed: 2892132]
  846. Minden A., Lin A., Claret F.X., Abo A., Karin M. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell. 1995;81:1147–1157. [PubMed: 7600582]
  847. Mitreiter K., Schmidt J., Luz A., Atkinson M.J., Hofler H., Erfle V.S. Disruption of the murine p53 gene by insertion of an endogenous retrovirus-like element (ETn) in a cell line from radiation-induced osteosarcoma. Virology. 1994;200:837–841. [PubMed: 8178469]
  848. Miura T., Shibuya M., Tsujimoto H., Fukasawa M., Hayami M. Molecular cloning of a feline leukemia provirus integrated adjacent to the c-myc gene in a feline T-cell leukemia cell line and the unique structure of its long terminal repeat. Virology. 1989;169:458–461. [PubMed: 2539700]
  849. Miyamoto K., Sato J., Kitajima K.-I., Togawa A., Suemaru S., Sanada H., Tanaka T. Adult T-cell leukemia. Cancer. 1983;52:471–473. [PubMed: 6602649]
  850. Miyamoto K., Tomita N., Ishii A., Nishizaki T., Kitajima K., Tanaka T., Nakamura T., Watanabe S., Oda T. Transformation of ATLA-negative leukocytes by blood components from anti-ATLA-positive donors in vitro. Int. J. Cancer. 1984;33:721–725. [PubMed: 6329965]
  851. Miyamoto S., Verma I.M. Rel/NF-kappa B/I kappa B story. Adv. Cancer Res. 1995;66:255–292. [PubMed: 7793317]
  852. Miyazawa M., Nishio J., Wehrly K., Chesebro B. Influence of MHC genes on spontaneous recovery from Friend retrovirus-induced leukemia. J. Immunol. 1992a;148:644–647. [PubMed: 1729380]
  853. Miyazawa M., Nishio J., Wehrly K., David C.S., Chesebro B. Spontaneous recovery from Friend retrovirus-induced leukemia. Mapping of the Rfv2 gene in the Q/TL region of the mouse MHC. J. Immunol. 1992b;148:1964–1967. [PubMed: 1541833]
  854. Miyazawa M., Nishio J., Wehrly K., Jay G., Melvold R.W., Chesebro B. Detailed mapping of the Rfv1 gene that influences spontaneous recovery from Friend retrovirus-induced leukaemia. Eur. J. Immunogenet. 1992c;19:159–164. [PubMed: 1627536]
  855. Miyoshi I., Kubonishi I., Yoshimoto S., Akagi T., Ohtusuki Y., Shiraisi Y., Nagata K., Hinuma Y. Type C virus particles in a cord T-cell line derived by cocultivating normal human cord leukocytes and human leukaemic T cells. Nature. 1983;294:770–771. [PubMed: 6275274]
  856. Miyoshi J., Miyoshi Y., Sasai H., Sakai N., Katsumata T., Kakunaga T. Differential requirements of Gag and γ-actin domains for transforming potential of Gardner-Rasheed feline sarcoma virus. J. Virol. 1989;63:1174–1180. [PMC free article: PMC247812] [PubMed: 2536827]
  857. Moelling K., Heimann B., Beimling P., Rapp U.R., Sander T. Serine- and threonine-specific protein kinase activities of purified Gag-Mil and Gag-Raf proteins. Nature. 1984;312:558–561. [PubMed: 6438534]
  858. Moloney J.B. Biological studies on a lymphoid-leukemia virus extracted from sarcoma 37. I. Origin and introductory investigations. J. Natl. Cancer Inst. 1960;24:933–951. [PubMed: 14423465]
  859. Moloney J.B. A virus-induced rhabdomyosarcoma of mice. Natl Cancer Inst. Monogr. 1966;22:139–142. [PubMed: 4288557]
  860. Montelaro R.C., Ball J.M., Rushlow K.E. 1993Equine retroviruses In The retroviridae (ed. J.A. Levy), pp. 257–360. Plenum Press, New York.
  861. Montelaro R.C., Parekh B., Orrego A., Issel C.J. Antigenic variation during persistent infection by equine infectious anemia virus, a retrovirus. J. Biol. Chem. 1984;259:10539–10544. [PubMed: 6206055]
  862. Moodie S.A., Williumsen B.M., Weber M.J., Wolfman A. Complexes of Ras-GTP with Raf-1 and MAP kinase kinase. Science. 1993;260:1658–1661. [PubMed: 8503013]
  863. Mooslehner K., Karls U., Harbers K. Retroviral integration sites in transgenic Mov mice frequently map in the vicinity of transcribed DNA regions. J. Virol. 1990;64:3056–3058. [PMC free article: PMC249491] [PubMed: 2335826]
  864. Moreau-Gachelin F., Tavitian A., Tambourin P. Spi1 is a putative oncogene in virally induced murine erythroleukaemias. Nature. 1988;331:277–280. [PubMed: 2827041]
  865. Moreau-Gachelin F., Ray D., Mattei M.G., Tambourin P., Tavitian A. The putative oncogene Spi1: Murine chromosomal localization and transcriptional activation in murine acute erythroleukemias. Oncogene. 1989;4:1449–1456. [PubMed: 2594367]
  866. Moreau-Gachelin F., Ray D., de Both N.J., van der Feltz M.J., Tambourin P., Tavitian A. Spi1 oncogene activation in Rauscher and Friend murine virus-induced acute erythroleukemias. Leukemia. 1990;4:20–23. [PubMed: 2153262]
  867. Morey M.K., Wiley C.A. Immunohistochemical localization of neurotropic ecotropic murine leukemia virus in moribund mice. Virology. 1990;178:104–112. [PubMed: 2167545]
  868. Morgan I.M., Asano M., Havarstein L.S., Ishikawa H., Hiragi T., Ito Y., Vogt P.K. Amino acid substitutions modulate the effect of Jun on transformation, transcriptional activation and DNA replication. Oncogene. 1993;8:1135–1140. [PubMed: 8479738]
  869. Morimoto C., Matsuyama T., Oshige C., Tanaka H., Hercend T., Reinherz E.L., Schlossman S.F. Functional and phenotypic studies of Japanese adult T-cell leukemia cells. J. Clin. Invest. 1985;75:836–843. [PMC free article: PMC423612] [PubMed: 2858496]
  870. Morishita K., Parker D.S., Mucenski M.L., Jenkins N.A., Copeland N.G., Ihle J.N. Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines. Cell. 1988;54:831–840. [PubMed: 2842066]
  871. Morrison H.L., Soni B., Lenz J. Long terminal repeat enhancer core sequences in proviruses adjacent to c-myc in T-cell lymphomas induced by a murine retrovirus. J. Virol. 1995;69:446–455. [PMC free article: PMC188593] [PubMed: 7983741]
  872. Morrison R.P., Nishio J., Chesebro B. Influence of the murine MHC (H-2) on Friend leukemia virus-induced immunosuppression. J. Exp. Med. 1986;163:301–314. [PMC free article: PMC2188032] [PubMed: 3456010]
  873. Morse H.C. III, Chattopadhyay S.K., Makino M., Fredrickson T.N., Hugin A.W., Hartley J.W. Retrovirus-induced immunodeficiency in the mouse: MAIDS as a model for AIDS. AIDS. 1992;6:607–621. [PubMed: 1503680]
  874. Morse H.C. III, Yetter R.A., Via C.S., Hardy R.R., Cerney A., Hayakawa K., Hugin A.W., Miller M.W., Holmes K.L., Shearer G.M. Functional and phenotypic alterations in T cell subsets during the course of MAIDS, a murine retrovirus-induced immunodeficiency syndrome. J. Immunol. 1989;143:844–850. [PubMed: 2545779]
  875. Moscovici C., Gazzolo L. Transformation of hemopoietic cells with avian leukemia viruses. Adv. Viral Oncol. 1982;1:83–106.
  876. Moscovici M.G., Moscovici C. Isolation and characterization of a temperature-sensitive mutant of avian myeloblastosis virus. Proc. Natl. Acad. Sci. 1983;80:1421–1425. [PMC free article: PMC393609] [PubMed: 6298790]
  877. Moscovici M.G., Jurdic P., Samarut J., Gazzolo L., Mura C.V., Moscovici C. Characterization of hematopoietic target cells for the avian leukemia virus E26. Virology. 1983;129:65–78. [PubMed: 6310886]
  878. Mosier D.E., Yetter R.A., Morse H.C. III. Retroviral induction of acute lymphoproliferative disease and profound immunosuppression in adult C57BL/6 mice. J. Exp. Med. 1985;161:766–784. [PMC free article: PMC2189053] [PubMed: 2984305]
  879. Mosier D.E., Yetter R.A., Morse H.C. III. Functional T lymphocytes are required for a murine retrovirus-induced immunodeficiency disease (MAIDS). J. Exp. Med. 1987;165:1737–1742. [PMC free article: PMC2188367] [PubMed: 3035057]
  880. Moskow J.J., Bullrich F., Huebner K., Daar I.O., Buchberg A.M. Meis1, a Pbx1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol. Cell. Biol. 1995;15:5435–5443. [PMC free article: PMC230793] [PubMed: 7565694]
  881. Motta J.V., Crittenden L.B., Purchase H.G., Stone H.A., Witter R.L. Low oncogenic potential of avian endogenous RNA tumor virus infection or expression. J. Natl. Cancer Inst. 1975;55:685–689. [PubMed: 169382]
  882. Mowat M., Cheng A., Kimura N., Bernstein A., Benchimol S. Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus. Nature. 1985;314:633–636. [PubMed: 3990796]
  883. Mucenski M.L., Gilbert D.J., Taylor B.A., Jenkins N.A., Copeland N.G. Common sites of viral integration in lymphomas arising in AKXD recombinant inbred mouse strains. Oncogene Res. 1987;2:33–48. [PubMed: 3505665]
  884. Mucenski M.L., Taylor B.A., Ihle J.N., Hartley J.W., Morse H.C., Jenkins N.A., Copeland N.G. Identification of a common ecotropic viral integration site, Evi-1, in the DNA of AKXD murine myeloid tumors. Mol. Cell. Biol. 1988;8:301–308. [PMC free article: PMC363121] [PubMed: 2827004]
  885. Mukhopadhyaya R., Wolff L. New sites of proviral integration associated with murine promonocytic leukemias and evidence for alternate modes of c-myb activation. J. Virol. 1992;66:6035–6044. [PMC free article: PMC241481] [PubMed: 1527851]
  886. Mukhopadhyaya R., Richardson J., Nazarov V., Corbin A., Koller R., Sitbon M., Wolff L. Different abilities of Friend murine leukemia virus (MuLV) and Moloney MuLV to induce promonocytic leukemia are due to determinants in both ψ-gag-PR and env regions. J. Virol. 1994;68:5100–5107. [PMC free article: PMC236453] [PubMed: 7518530]
  887. Muller R., Bravo R., Burckjardt J., Curran T. Induction of c-fos gene and protein by growth factors precedes activation of c-myc. Nature. 1984;314:546–548. [PubMed: 6334806]
  888. Mullins J.I., Chen C.S., Hoover E.A. Disease-specific and tissue-specific production of unintegrated feline leukaemia virus variant DNA in feline AIDS. Nature. 1986;319:333–336. [PubMed: 3001539]
  889. Mullins J.I., Brody D.S., Binari R.C. Jr., Cotter S.M. Viral transduction of c-myc oncogene in naturally occurring feline leukaemias. Nature. 1984;308:856–858. [PubMed: 6325922]
  890. Munroe D.G., Peacock J.W., Benchimol A. Inactivation of the cellular p53 gene is a common feature of Friend virus-induced erythroleukemia: Relationship of inactivation to dominant transforming alleles. Mol. Cell. Biol. 1990;10:3307–3313. [PMC free article: PMC360748] [PubMed: 1694008]
  891. Munroe D.G., Rovinski B., Bernstein A., Benchimol S. Loss of a highly conserved domain of p53 as a result of gene deletion during Friend virus-induced erythroleukemia. Oncogene. 1988;2:621–624. [PubMed: 3290808]
  892. Murakami K.M., Okada K., Ikawa Y., Aida Y. Bovine leukemia virus induces CD5 B cell lymphoma in sheep despite temporarily increasing CD5+ B cells in asymptomatic stage. Virology. 1994;202:458–465. [PubMed: 7516599]
  893. Muralidhar G., Koch S., Haas M., Swain S.L. CD4 T cells in murine acquired immunodeficiency syndrome: Polyclonal progression to anergy. J. Exp. Med. 1992;175:1589–1599. [PMC free article: PMC2119230] [PubMed: 1588283]
  894. Murphy E.L., Hanchard B., Figueroa J.P., Gibbs W.N., Lofters W.S., Campbell M., Goedert J.J., Blattner W.A. Modeling the risk of adult T-cell leukemia/lymphoma in persons infected with human T-lymphotropic virus type I. Int. J. Cancer. 1989;43:250–253. [PubMed: 2917802]
  895. Murphy E.L., Figueroa J.P., Gibbs W.N., Holding-Cobham M., Cranston B., Malley K., Bodner A.J., Alexander S.S., Blattner W.A. Human T-lymphotropic virus type I (HTLV-I) seroprevalence in Jamaica. Am. J. Epidemiol. 1991;133:1114–1124. [PubMed: 2035515]
  896. Mushinski J.F., Potter M., Bauer S.R., Reddy E.P. DNA rearrangement and altered RNA expression of the c-myb oncogene in mouse plasmacytoid lymphosarcomas. Science. 1983;220:795–798. [PubMed: 6687762]
  897. Mussman H.C., Twiehaus M.J. Pathogenesis of reticuloendothelial virus disease in chicks—An acute runting syndrome. Avian Dis. 1971;15:483–502. [PubMed: 4329203]
  898. Nagra R.M., Burrola P.G., Wiley C.A. Development of spongiform encephalopathy in retroviral infected mice. Lab. Invest. 1992;66:292–302. [PubMed: 1311397]
  899. Nagy K., Clapham P., Cheinsong-Popov R., Weiss R.A. Human T-cell leukemia virus type-I: Induction of syncytia and inhibition by patient's sera. Int. J. Cancer. 1983;32:321–328. [PubMed: 6604033]
  900. Naharro G., Robbins K.C., Reddy E.P. Gene product of v-fgr onc: Hybrid protein containing a portion of actin and a tyrosine-specific protein kinase. Science. 1984;223:63–66. [PubMed: 6318314]
  901. Nakamura T., Largaespada D.A., Shaughnessy J.D. Jr., Jenkins N.A., Copeland N.G. Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias. Nat. Genet. 1996;12:149–153. [PubMed: 8563752]
  902. Nakano S., Ando Y., Ichijo M., Moriyama I., Saito S., Sugamura K., Hinuma Y. Search for possible routes of vertical and horizontal transmission of adult T-cell leukemia virus. Gann. 1984;75:1044–1045. [PubMed: 6098502]
  903. Narayan O., Cork L.C. Lentiviral diseases of sheep and goats: Chronic pneumonia, leukoencephalomyelitis, and arthritis. Rev. Infect. Dis. 1985;7:89–98. [PubMed: 3885367]
  904. Narayan O., Kennedy-Stoskopf S., Sheffer D., Griffin D., Clements J.E. Activation of caprine arthritis encephalitis virus expression during maturation of monocytes macrophages. Infect. Immun. 1983;41:67–73. [PMC free article: PMC264744] [PubMed: 6862634]
  905. Narayan O., Wolinsky J.S., Clements J.E., Strandberg J.D., Griggin D.E., Cork L.C. Slow virus replication: The role of macrophages in the persistence and expression of visna virus of sheep and goats. J. Gen. Virol. 1982;59:345–356. [PubMed: 6281373]
  906. Narayan O., Zink M.C., Gorrell M., Crane S., Huso D., Jolly P., Saltarelli M., Adams R.J., Clements J.E. 1993The lentiviruses of sheep and goats In The retroviridae (ed. J.A. Levy), pp. 229–256. Plenum Press, New York. [PMC free article: PMC47500]
  907. Nason-Burchenal K., Wolff L. Activation of c-myb is an early bone-marrow event in a murine model for acute promonocytic leukemia. Proc. Natl. Acad. Sci. 1993;90:1619–1623. [PMC free article: PMC45926] [PubMed: 7679511]
  908. Nazarov V., Wolff L. Novel integration sites at the distal 3′ end of the c-myb locus in retrovirus-induced promonocytic leukemias. J. Virol. 1995;69:3885–3888. [PMC free article: PMC189110] [PubMed: 7745739]
  909. Nebreda A.R., Hunt T. The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs. EMBO J. 1993;12:1979–1986. [PMC free article: PMC413419] [PubMed: 8387916]
  910. Neel B.G., Hayward W.S., Robinson H.L., Fang J., Astrin S.M. Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: Oncogenesis by promoter insertion. Cell. 1981;23:323–334. [PubMed: 6258798]
  911. Neel B.G., Wang L.H., Mathey-Prevot B., Hanafusa T., Hanafusa H., Hayward W.S. Isolation of 16L virus: A rapidly transforming sarcoma virus from an avian leukosis virus-induced sarcoma. Proc. Natl. Acad. Sci. 1982a;79:5088–5092. [PMC free article: PMC346833] [PubMed: 6289331]
  912. Neel B.G., Gasic G.P., Rogler C.E., Skalka A.M., Ju G., Hishinuma F., Papas T., Astrin S.M., Hayward W.S. Molecular analysis of the c-myc locus in normal tissue and in avian leukosis virus-induced lymphomas. J. Virol. 1982b;44:158–166. [PMC free article: PMC256249] [PubMed: 6292482]
  913. Nehls M., Pfeifer D., Schorpp M., Hedrich H., Boehm T. New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature. 1994;372:103–107. [PubMed: 7969402]
  914. Neil J.C., Fulton R., Rigby M., Stewart M. Feline leukaemia virus: Generation of pathogenic and oncogenic variants. Curr. Top. Microbiol. Immunol. 1991;171:67–93. [PubMed: 1667630]
  915. Neil J.C., Hughes D., McFarlane R., Wilkie N.M., Onions D.E., Lees G., Jarrett O. Transduction and rearrangement of the myc gene by feline leukaemia virus in naturally occurring T-cell leukaemias. Nature. 1984;308:814–820. [PubMed: 6325920]
  916. Neiman P.E., Jordan L., Weiss R.A., Payne L.N. Malignant lymphoma of the bursa of Fabricius: Analysis of early transformation. Cold Spring Harbor Conf. Cell Prolif. 1980;7:519–528.
  917. Nerenberg M., Hinrichs S.H., Reynolds R.K., Khoury G., Jay G. The tat gene of human T-lymphotropic virus type I induces mesenchymal tumors in transgenic mice. Science. 1987;237:1324–1329. [PubMed: 2888190]
  918. Ness S.A., Marknell A., Graf T. The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene. Cell. 1989;59:1115–1125. [PubMed: 2688896]
  919. Ness S.A., Kowenz-Leuta E., Casini T., Graf T., Leutz A. Myb and NF-M: Combinatorial activators of myeloid genes in heterologous cell types. Genes Dev. 1993;7:749–759. [PubMed: 7684005]
  920. Nilsen T.W., Maroney P.A., Goodwin R.G., Rottman F.M., Crittenden L.B., Raines M.A., Kung H.J. c-erbB activation in ALV-induced erythroblastosis: Novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor. Cell. 1985;41:719–726. [PubMed: 2988784]
  921. Nimer S.D., Gasson J.C., Hu K., Smalberg I., Chen I.S.Y., Rosenblatt J.D. Activation of the GM-CSF promoter by HTLV-I and HTLV-II Tax proteins. Oncogene. 1989;4:671–676. [PubMed: 2660069]
  922. Nishimura J., Huang J.S., Deuel T.F. Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes. Proc. Natl. Acad. Sci. 1982;79:4303–4307. [PMC free article: PMC346659] [PubMed: 6181505]
  923. Nishizawa M., Goto N., Kawai S. An avian transforming retrovirus isolated from a nephroblastoma that carries the fos gene as the oncogene. J. Virol. 1987;61:3733–3740. [PMC free article: PMC255986] [PubMed: 2824811]
  924. Noori-Daloii M.R., Swift R.A., Kung H.J., Crittenden L.B., Witter R.L. Specific integration of REV proviruses in avian bursal lymphomas. Nature. 1981;294:574–576. [PubMed: 6273749]
  925. Norley S., Kurth R. 1994Immune response to retroviral infection In The retroviridae (ed. J.A. Levy), vol. 3, pp. 363–464. Plenum Press, New York.
  926. Nottenburg C., Stubblefield E., Varmus H.E. An aberrant avian leukosis virus provirus inserted downstream from the chicken c-myc coding sequence in a bursal lymphoma results from intrachromosomal recombination between two proviruses and deletion of cellular DNA. J. Virol. 1987;61:1828–1833. [PMC free article: PMC254186] [PubMed: 3033315]
  927. Nunn M., Weiherm H., Bullock P., Duesberg P. Avian erythroblastosis virus E26: Nucleotide sequence of the tripartite onc gene and of the LTR, and analysis of the cellular prototype of the viral ets sequence. Virology. 1984;139:330–339. [PubMed: 6097027]
  928. Nusse R., Varmus H.E. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell. 1982;31:99–109. [PubMed: 6297757]
  929. Nusse R., van Ooyen A., Cox D., Fung Y.K., Varmus H. Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature. 1984;307:131–136. [PubMed: 6318122]
  930. Nusse R., Theunissen H., Wagenaar E., Rijsewijk F., Gennissen A., Otte A., Schuuring E., van Ooyen A. The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus. Mol. Cell. Biol. 1990;10:4170–4179. [PMC free article: PMC360946] [PubMed: 1695322]
  931. Nyborg J.K., Dynan W.S. Interaction of cellular proteins with the human T-cell leukemia virus type I transcriptional control region: Purification of cellular proteins that bind the 21-base pair repeat elements. J. Biol. Chem. 1990;265:8230–8236. [PubMed: 2335523]
  932. Nyborg J.K., Dynan W.S., Chen I.S.Y., Wachsman W. Binding of host-cell factors to DNA sequences in the long terminal repeat of human T-cell leukemia virus type I: Implications for viral gene expression. Proc. Natl. Acad. Sci. 1988;85:1457–1461. [PMC free article: PMC279790] [PubMed: 2830620]
  933. Odaka T. Inheritance of susceptibility to Friend mouse leukemia virus. Int. J. Cancer. 1970;6:18–23. [PubMed: 4319230]
  934. Odaka T., Yamamoto T. Inheritance of susceptibility to Friend mouse leukemia virus II. Spleen foci method applied to test the susceptibility of crossbred progeny between a sensitive and a resistant strain. Jpn. J. Exp. Med. 1965;35:311–314. [PubMed: 5295573]
  935. Odaka T., Ikeda H., Yoshikura H., Moriwaki K., Suzuki S. Fv4: Gene controlling resistance to NB-tropic Friend murine leukemia virus. Distribution in wild mice, introduction into genetic background of BALB/c mice, and mapping of chromosomes. J. Natl. Cancer Inst. 1981;67:1123–1127. [PubMed: 6946250]
  936. O'Donnell P.V., Woller R., Chu A. Stages in the development of mink cell focus-inducing (MCF) virus-accelerated leukemia in AKR mice. J. Exp. Med. 1984;160:914–934. [PMC free article: PMC2187407] [PubMed: 6236277]
  937. O'Donnell P.V., Stockert E., Obata T., Old L.J. Leukemogenic properties of AKR dual tropic (MCF) viruses: Amplification of murine leukemia virus-related antigens on thymocytes and acceleration of leukemia development in AKR mice. Virology. 1981;112:548–563. [PubMed: 6266139]
  938. O'Donnell P.V., Fleissner E., Lonial H., Koehne C.F., Reicin A. Early clonality and high-frequency proviral integration into the c-myc locus in AKR leukemias. J. Virol. 1985;55:500–503. [PMC free article: PMC254961] [PubMed: 2991574]
  939. Officer J.E., Tecson N., Estes J.D., Fontanilla E., Rongey R.W., Gardner M.B. Isolation of a neurotropic type C virus. Science. 1973;181:945–947. [PubMed: 4354228]
  940. Oka T., Sonobe H., Iwata J., Kubonishi I., Satoh H., Takata M., Tanaka Y., Tateno M., Tozawa H., Mori S., Yoshiki T., Ohtsuki Y. Phenotypic progression of a rat lymphoid cell line immortalized by human T-lymphotropic virus type I to induce lymphoma/leukemia-like disease in rats. J. Virol. 1992;66:6686–6694. [PMC free article: PMC240164] [PubMed: 1404610]
  941. Okazaki K., Sagata N. MAP kinase activation is essential for oncogenic transformation of NIH3T3 cells by Mos. Oncogene. 1995;10:1149–1157. [PubMed: 7700641]
  942. Oker-Blom N., Kallio A., Hortling L. Morphological changes in chick embryo cell cultures induced by avian leukosis viruses. Intervirology. 1975;5:342–353. [PubMed: 181344]
  943. Oker-Blom N., Hortling L., Kallio A., Nurmiaho E.-L., Westermarck H. OK 10 virus, an avian retrovirus resembling the acute leukaemic viruses. J. Gen. Virol. 1978;40:623–633. [PubMed: 211198]
  944. Oldstone M.B.A., Lampert P.W., Lee S., Dixon F.J. Pathogenesis of the slow-disease of the central nervous system associated with VM 1504 E virus. Am. J. Clin. Pathol. 1977;88:193–206. [PMC free article: PMC2032160] [PubMed: 195470]
  945. Olmsted R.A., Hirschum V.M., Purcell R.H., Johnson P.R. Nucleotide sequence analysis of feline immunodeficiency virus: Genetic organization and relationship to other lentiviruses. Proc. Natl. Acad. Sci. 1989;86:8088–8092. [PMC free article: PMC298220] [PubMed: 2813380]
  946. Olmsted R.A., Langley R., Roelke M.E., Goeken R.M., Adger-Johnson D., Goff J.P., Albert J.P., Packer C., Laurenson M.K., Caro T.M., Scheepers. D.E. Wildt L., Bush M., Martenson J.S., O'Brien S.J. Worldwide prevalence of lentivirus infection in wild feline species: Epidemiologic and phylogenetic aspects. J. Virol. 1992;66:6008–6018. [PMC free article: PMC241478] [PubMed: 1382145]
  947. Olson C., Miller J.M., Miller L.D., Gillette K.G. C-type virus and lymphocytotic nuclear projections in bovine lymphosarcoma. J. Am. Vet. Med. Assoc. 1970;156:571–578. [PubMed: 4986933]
  948. Olson C., Miller L., Miller J., Hoss H. Transmission of lymphosarcoma from cattle to sheep. J. Natl. Cancer Inst. 1972;49:1463–1467. [PubMed: 4346541]
  949. O'Neill L.L., Burkhard M.J., Diehl L.J., Hoover E.A. Vertical transmission of feline immunodeficiency virus. AIDS Res. Hum. Retroviruses. 1995;11:171–182. [PubMed: 7734190]
  950. Onions D., Lees G., Forrest D., Neil J. Recombinant feline viruses containing the myc gene rapidly produce clonal tumours expressing T-cell antigen receptor gene transcripts. Int. J. Cancer. 1987;40:40–45. [PubMed: 3036720]
  951. Onions D., Jarrett O., Testa N., Frassoni F., Toth S. Selective effect of feline leukaemia virus on early erythroid precursors. Nature. 1982;296:156–158. [PubMed: 6278316]
  952. Oprandy J.J., Chang P.W., Pronovost A.D., Cooper K.R., Brown R.S., Yates V.J. Isolation of a viral agent causing hematopoietic neoplasia in the soft-shell clam, Mya arenaria. J. Invertebr. Pathol. 1981;38:45–51.
  953. Orrego A., Issel C.J., Montelaro R.C., Adams W.V. Virulence and in vitro growth of a cell-adapted strain of equine infectious anemia virus after serial passage in ponies. Am. J. Vet. Res. 1982;43:1556–1560. [PubMed: 6293349]
  954. Osame M., Igata A., Usuku K., Rosales R., Matsumoto M. Mother-to-child transmission in HTLV-I-associated myelopathy. Lancet. 1987;I:106. [PubMed: 2879161]
  955. Osame M., Izumo S., Igata A., Matsumoto M., Matsumoto T., Sonda S., Tara M., Shibata Y. Blood transfusion and HTLV-I-associated myelopathy. Lancet. 1986a;II:104–105. [PubMed: 2873363]
  956. Osame M., Usuku K., Izumo S., Ijichi N., Amitani H., Igata A., Matsumoto M., Tara M. HTLV-I-associated myelopathy: A new clinical entity. Lancet. 1986b;I:1031–1032. [PubMed: 2871307]
  957. Ott D., Rein A. Basis for receptor specificity of nonecotropic murine leukemia virus surface glycoprotein gp70SU. J. Virol. 1992;66:4632–4638. [PMC free article: PMC241286] [PubMed: 1321266]
  958. Ott D.E., Keller J., Sill K., Rein A. Phenotypes of murine leukemia virus-induced tumors: Influence of 3′ viral coding sequences. J. Virol. 1992;66:6107–6116. [PMC free article: PMC241488] [PubMed: 1326661]
  959. Ou C.-Y., Boone L.R., Koh C.-K., Tennant R.W., Yang W.K. Nucleotide sequences of gag-pol regions that determine the Fv-1 host range property of BALB/c N-tropic and B-tropic murine leukemia viruses. J. Virol. 1983;48:779–784. [PMC free article: PMC255411] [PubMed: 6313971]
  960. Overbaugh J., Riedel N., Hoover E.A., Mullins J.I. Transduction of endogenous envelope genes by feline leukaemia virus in vitro. Nature. 1988a;332:731–734. [PubMed: 2895894]
  961. Overbaugh J., Donahue P.R., Quakenbush S.L., Hoover E.A., Mulllins J.I. Molecular cloning of a feline leukemia virus that induces fatal immunodeficiency disease in cats. Science. 1988b;239:906–910. [PubMed: 2893454]
  962. Overbaugh J., Hoover E.A., Mullins J.I., Burns D.P., Rudensey L., Quackenbush S.L., Stallard V., Donahue P.R. Structure and pathogenicity of individual variants within an immunodeficiency disease-inducing isolated of FeLV. Virology. 1992;188:558–569. [PubMed: 1316674]
  963. Pain B., Melet F., Jurdic P., Samarut J. The carbonic anhydrase II gene, a gene regulated by thyroid hormone and erythropoietin, is repressed by the v-erbA oncogene in erythrocytic cells. New Biol. 1990;2:284–294. [PubMed: 2126201]
  964. Palmarini M., Dewar P., De las Heras M., Inglis N.F., Dalziel R.G., Sharp J.M. Epithelial tumour cells in the lungs of sheep with pulmonary adenomatosis are major sites of replication for Jaagsiekte retrovirus. J. Gen. Virol. 1995;76:2731–2737. [PubMed: 7595380]
  965. Palmarini M.P., Cousens C., Dalziel R.G., Bai J., Stedman K., DeMartini J.C., Sharp J.M. The exogenous form of Jaagsiekte retrovirus is specifically associated with a contagious lung cancer of sheep. J. Virol. 1996;70:1618–1623. [PMC free article: PMC189985] [PubMed: 8627682]
  966. Palmieri S. Isolation of an MH2 retrovirus mutant temperature sensitive for macrophage but not fibroblast transformation. J. Virol. 1986;58:134–141. [PMC free article: PMC252885] [PubMed: 3005642]
  967. Palmieri S., Vogel M.L. Fibroblast transformation parameters induced by the avian v-mil oncogene. J. Virol. 1987;61:1717–1721. [PMC free article: PMC254163] [PubMed: 3573149]
  968. Paquette Y., Kay D.G., Rassart E., Robitaille Y., Jolicoeur P. Substitution of the U3 long terminal repeat region of the neurotropic Cas-Br-E retrovirus affects its disease-inducing potential. J. Virol. 1990;64:3742–3752. [PMC free article: PMC249669] [PubMed: 2164594]
  969. Paquette Y., Hanna Z., Savard P., Brosseau R., Robitaille Y., Jolicoeur P. Retrovirus-induced murine motor neuron disease: Mapping the determinant of spongiform degeneration within the envelope gene. Proc. Natl. Acad. Sci. 1989;86:3896–3900. [PMC free article: PMC287248] [PubMed: 2542954]
  970. Paquette Y., Doyon L., Laperriere A., Hanna Z., Ball J., Sekaly R.P., Jolicoeur P. A viral long terminal repeat expressed in CD4+ CD8+ precursors is downregulated in mature peripheral CD4 CD8+ or CD4+ CD8 T cells. Mol. Cell. Biol. 1992;12:3522–3530. [PMC free article: PMC364609] [PubMed: 1321339]
  971. Pardi D.J., Switzer W.M., Hadlock K.G., Kaplan J.E., Lai R.B., Folks T.M. Complete nucleotide sequence of an Amerindian human T-cell lymphotropic virus type II (HTLV-II) isolate: Identification of a variant HTLV-II subtype b from a Guaymi Indian. J. Virol. 1991;67:4569–4664. [PMC free article: PMC237851] [PubMed: 8331724]
  972. Park B.H., Lavi E., Gaulton G.N. Intracerebral hemorrhages and infarction induced by a murine leukemia virus is influenced by host determinants within endothelial cells. Virology. 1994a;203:393–396. [PubMed: 8053164]
  973. Park B.H., Lavi E., Blank K.J., Gaulton G.N. Intracerebral hemorrhages and syncytium formation induced by endothelial cell infections with a murine leukemia virus. J. Virol. 1993;67:6015–6024. [PMC free article: PMC238022] [PubMed: 8396666]
  974. Park B.H., Lavi E., Stieber A., Gaulton G.N. Pathogenesis of cerebral infarction and hemorrhage induced by a murine leukemia virus. Lab. Invest. 1994b;70:78–85. [PubMed: 8302022]
  975. Park B.H., Matuschke B., Lavi E., Gaulton G.N. A point mutation in the env gene of a murine leukemia virus induces syncytium formation and neurologic disease. J. Virol. 1994c;68:7516–7524. [PMC free article: PMC237194] [PubMed: 7933135]
  976. Park C.G., Jung M.Y., Choi Y., Winslow G.M. Proteolytic processing is required for viral superantigen activity. J. Exp. Med. 1995;181:1899–1904. [PMC free article: PMC2192000] [PubMed: 7722465]
  977. Pathak V.K., Strange R., Young L.J., Morris D.W., Cardiff R.D. Survey of int region DNA rearrangements in C3H and BALB/cfC3H mouse mammary tumor system. J. Natl. Cancer Inst. 1987;78:327–331. [PubMed: 3468297]
  978. Patriotis C., Makris A., Bear S.E., Tsichlis P.N. Tumor progression locus 2 (Tpl2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation. Proc. Natl. Acad. Sci. 1993;90:2251–2255. [PMC free article: PMC46064] [PubMed: 7681591]
  979. Patriotis C., Makris A., Chernoff J., Tsichlis P.N. Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase. Proc. Natl. Acad. Sci. 1994;91:9755–9759. [PMC free article: PMC44895] [PubMed: 7937886]
  980. Paul R., Schuetze S., Kozak S.L., Kabat D. A common site for immortalizing proviral integrations in Friend erythroleukemia: Molecular cloning and characterization. J. Virol. 1989;63:4958–4961. [PMC free article: PMC251145] [PubMed: 2552176]
  981. Pawson T. SH2 and SH3 domains in signal transduction. Adv. Cancer Res. 1994;64:87–110. [PubMed: 7533473]
  982. Pawson T. Protein modules and signaling networks. Nature. 1995;373:573–580. [PubMed: 7531822]
  983. Payne A., York D.F., De Villiers E.M., Verwoerd D.W., Querat G., Barban V., Sauze N., Vigne R. Isolation and identification of a South African lentivirus from jaagsiekte lungs. Onderstepoort J. Vet. Res. 1986;53:55–62. [PubMed: 3008059]
  984. Payne G.S., Bishop J.M., Varmus H.E. Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas. Nature. 1982;295:209–214. [PubMed: 6276760]
  985. Payne G.S., Courtneidge S.A., Crittenden L.B., Fadly A.M., Bishop J.M., Varmus H.E. Analysis of avian leukosis virus DNA and RNA in bursal tumours: Viral gene expression is not required for maintenance of the tumor state. Cell. 1981;23:311–322. [PubMed: 6258797]
  986. Payne L.N. 1992Biology of avian retroviruses In The retroviridae (ed. J.A. Levy), vol. 1, pp. 299–404. Plenum Press, New York.
  987. Payne L.N., Holmes A., Howes K., Pattison M., Waters D.E. Studies on the associations between natural infections of hens, cocks and their progeny with lymphoid leukosis virus. Avian Pathol. 1979;8:411–424. [PubMed: 18770468]
  988. Payne L.N., Holmes A., Howes K., Pattison M., Pollock D.L., Waters D.E. Further studies on the eradication and epizootiology of lymphoid leukosis virus infection in a commercial strain of chickens. Avian Pathol. 1982;11:145–150. [PubMed: 18770180]
  989. Payne S.L., Salinovich O., Nauman S.M., Issel C.J., Montelaro R.C. Course and extent of variation of equine infectious anemia virus during parallel persistent infections. J. Virol. 1987;61:1266–1270. [PMC free article: PMC254092] [PubMed: 3029423]
  990. Pedersen N.C. 1987Feline syncytium forming virus infection In Diseases of the cat (ed. J. Holsworth), pp. 268–278. W.B. Saunders, Philadelphia.
  991. Pedersen N.C. 1993The feline immunodeficiency virus In The retroviridae (ed. J.A. Levy), pp. 181–228. Plenum Press, New York. [PMC free article: PMC159128]
  992. Pedersen N.C., Barlough J.E. Clinical overview of feline immunodeficiency virus. J. Am. Vet. Med. Assoc. 1991;199:1298–1305. [PubMed: 1666071]
  993. Pedersen N.C., Ho E., Brown M.L., Yamamoto J.K. Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiencylike syndrome. Science. 1987;235:790–793. [PubMed: 3643650]
  994. Pedersen N.C., Theilen G.H., Keane M.A., Fairbanks L., Mason T., Orser B., Chen C., Allison C. Studies on naturally trasmitted feline leukemia virus infection. Am. J. Vet. Res. 1977;38:1523–1531. [PubMed: 201187]
  995. Pedersen N.C., Torten M., Rideout B., Sparger E., Tonachini T., Luciw P.A., Ackley C., Levy N., Yamamoto J. Feline leukemia virus infection as a potentiating cofactor for the primary and secondary stages of experimentally induced feline immunodeficiency virus infection. J. Virol. 1990;64:598–606. [PMC free article: PMC249149] [PubMed: 2153226]
  996. Pelley R.J., Maihle N.J., Boerkoel C., Shu H.K., Carter T.H., Moscovici C., Kung H.-J. Disease tropism of c-erbB: Effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation. Proc. Natl. Acad. Sci. 1988;86:7164–7168. [PMC free article: PMC298016] [PubMed: 2550929]
  997. Pellici G., Lanfrancone L., Grignani F., McGlade J., Cavillo F., Forni G., Nicoletti L., Grignani L., Pawson T., Pellici P.G. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell. 1992;70:93–104. [PubMed: 1623525]
  998. Peluso R., Haase A.T., Stowring L., Edwards M., Ventura P. A Trojan horse mechanism for the spread of visna in monocytes. Virology. 1985;147:231–236. [PubMed: 2998068]
  999. Perk K., Hod I. Sheep lung carcinoma: An epidemic analogue of a human neoplasm. J. Natl. Cancer Inst. 1982;69:747–750. [PubMed: 6288989]
  1000. Perry L.L., Wilkerson M.J., Hullinger G.A., Cheevers W.P. Depressed CD4+ T lymphocyte proliferative response and enhanced antibody response to viral antigen in chronic lentivirus-induced arthritis. J. Infect. Dis. 1995;171:328–334. [PubMed: 7844368]
  1001. Perry L.L., Miyazawa M., Hasenkrug K., Wehrly K., David C.S., Cheseboro B. Contrasting effects from a single major histocompatibility complex class II molecule (H-2E) in recovery from Friend virus leukemia. J. Virol. 1994;68:4921–4926. [PMC free article: PMC236432] [PubMed: 8035490]
  1002. Perryman L.E., O'Rourke K.I., McGuire T.C. Immune responses are required to terminate viremia in equine infectious anemia lentivirus infection. J. Virol. 1988;61:3073–3076. [PMC free article: PMC253753] [PubMed: 2839723]
  1003. Peschle C., Migliaccio G., Lettieri F., Migliaccio A.R., Ceccarelli R., Barba P., Titti F., Rossi G.B. Kinetics of erythroid precursors in mice infected with the anemic or the polycythemic strain of Friend virus. Proc. Natl. Acad. Sci. 1980;77:2054–2058. [PMC free article: PMC348650] [PubMed: 6929538]
  1004. Peters G. Oncogenes at viral integration sites. Cell Growth Differ. 1990;1:503–510. [PubMed: 2278881]
  1005. Peters G., Lee A.E., Dickson C. Concerted activation of two potential proto-oncogenes in carcinomas induced by mouse mammary tumour virus. Nature. 1986;320:628–631. [PubMed: 3010125]
  1006. Peters G., Brookes S., Smith R., Dickson C. Tumorigenesis by mouse mammary tumor virus: Evidence for a common region for provirus integration in mammary tumors. Cell. 1983;33:369–377. [PubMed: 6305506]
  1007. Peters G., Brookes S., Smith R., Placzek M., Dickson C. The mouse homolog of the HST/K-FGF gene is adjacent to Int-2 and is activated by proviral insertion in some virally induced mammary tumors. Proc. Natl. Acad. Sci. 1989a;86:5678–5682. [PMC free article: PMC297693] [PubMed: 2548184]
  1008. Peters G., Brookes S., Placzek M., Schuermann M., Michalides R., Dickson C. A putative int domain for mouse mammary tumor virus on mouse chromosome 7 is a 5′ extension of int-2. J. Virol. 1989b;63:1448–1450. [PMC free article: PMC247849] [PubMed: 2536846]
  1009. Peters R.L., Rabstein L.S., VanVleck R., Kelloff G.J., Huebner R.J. Naturally occurring sarcoma virus of the BALB/cCR mouse. J. Natl. Cancer Inst. 1974;53:1725–1729. [PubMed: 4373578]
  1010. Petursson G. Experience with visna virus in Iceland. Ann. N.Y. Acad. Sci. 1994;724:43–49. [PubMed: 8030970]
  1011. Phillips T.R., Talbot R.L., Lamont C., Muir S., Lovelace K., Elder J.H. Comparison of two host cell range variants of feline immunodeficiency virus. J. Virol. 1990;64:4605–4613. [PMC free article: PMC247944] [PubMed: 1697907]
  1012. Piccardo P., Ceroni M., Rodgers-Johnson P., Mora C., Asher D.M., Char G., Gibbs C.J. Jr., Gajdusek D.C. Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica. Ann. Neurol. 1988;23 (suppl.):S156–S160. [PubMed: 2894808]
  1013. Pierce J.H. Oncogenes, growth factors and hematopoietic cell transformation. Biochim. Biophys. Acta. 1989;989:179–208. [PubMed: 2557086]
  1014. Pincus T., Hartley J.W., Rowe W.P. A major genetic locus affecting resistance to infection with murine leukemia viruses. I. Tissue culture studies of naturally occurring viruses. J. Exp. Med. 1971;133:1219–1233. [PMC free article: PMC2138932] [PubMed: 4325132]
  1015. Pitts O.M., Powers J.M., Bilello J.A., Hoffman P.M. Ultrastructural changes associated with retroviral replication in central nervous system capillary endothelial cells. Lab. Invest. 1987;56:401–408. [PubMed: 3031367]
  1016. Piwnica-Worms H., Saunders K.B., Roberts T.M., Smith A.E., Cheng S.H. Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src. Cell. 1987;49:75–82. [PubMed: 3103926]
  1017. Pizer E., Humphries E.H. RAV-1 insertional mutagenesis: Disruption of the c-myb locus and development of avian B-cell lymphomas. J. Virol. 1989;63:1630–1640. [PMC free article: PMC248408] [PubMed: 2538646]
  1018. Pizer E.S., Baba T.W., Humphries E.H. Activation of the c-myb locus is insufficient for the rapid induction of disseminated avian B-cell lymphoma. J. Virol. 1992;66:512–523. [PMC free article: PMC238312] [PubMed: 1309260]
  1019. Poirier Y., Jolicoeur P. Distinct helper virus requirements for Abelson murine leukemia virus-induced pre-B and T-cell lymphomas. J. Virol. 1989;63:2088–2098. [PMC free article: PMC250625] [PubMed: 2539505]
  1020. Poirier Y., Kozak C., Jolicoeur P. Identification of a common helper provirus integration site in Abelson murine leukemia virus-induced lymphoma DNA. J. Virol. 1988;62:3985–3992. [PMC free article: PMC253826] [PubMed: 2845118]
  1021. Poiesz B.J., Ruscetti F.W., Gazdar A.F., Bunn P.A., Minna J.D., Gallo R.C. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc. Natl. Acad. Sci. 1980;77:7415–7419. [PMC free article: PMC350514] [PubMed: 6261256]
  1022. Polakis P. Mutations in the APC gene and their implications for protein structure and function. Curr. Opin. Genet. Dev. 1995;5:66–71. [PubMed: 7749328]
  1023. Polte T.R., Hanks S.K. Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas. Proc. Natl. Acad. Sci. 1995;92:10678–10682. [PMC free article: PMC40675] [PubMed: 7479864]
  1024. Popovic M., Lange-Wantzin G., Sarin P.S., Mann D., Gallo R.C. Transformation of human umbilical cord blood T cells by human T-cell leukemia/lymphoma virus. Proc. Natl. Acad. Sci. 1983;80:5402–5406. [PMC free article: PMC384264] [PubMed: 6604273]
  1025. Portis J.L. Wild mouse retrovirus: Pathogenesis. Curr. Top. Microbiol. Immunol. 1990;160:11–27. [PubMed: 2162283]
  1026. Portis J.L., Perryman S., McAtee F.J. The R-U5-5′ leader sequence of neurovirulent wild mouse retrovirus contains an element controlling the incubation period of neurodegenerative disease. J. Virol. 1991;65:1877–1883. [PMC free article: PMC239999] [PubMed: 2002548]
  1027. Portis J.L., Czub S., Garon C.F., McAtee F.J. Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend murine leukemia virus. J. Virol. 1990;64:1648–1656. [PMC free article: PMC249301] [PubMed: 2181155]
  1028. Portis J.L., Czub S., Robertson S., McAtee F., Chesebro B. Characterization of a neurological disease induced by a polytropic murine retrovirus. Evidence for differential targeting of ecotropic and polytropic viruses in the brain. J. Virol. 1995;69:8070–8075. [PMC free article: PMC189756] [PubMed: 7494324]
  1029. Posada J., Yew N., Ahn N.G., Vande Woude G.F., Cooper J.A. Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro. Mol. Cell. Biol. 1993;13:2546–2553. [PMC free article: PMC359584] [PubMed: 8384311]
  1030. Poulet F.M., Bower P.R., Casey J.W. 1994Retroviruses of fish, reptiles, and molluscs In The retroviridae (ed. J.A. Levy), vol. 3, pp. 1–38. Plenum Press, New York. [PMC free article: PMC159657]
  1031. Pozsgay J.M., Reid S., Pitha P.M. Dissociation between lymphoproliferative responses and virus replication in mice with different sensitivities to retrovirus-induced immunodeficiency. J. Virol. 1993a;67:980–988. [PMC free article: PMC237452] [PubMed: 8380473]
  1032. Pozsgay J.M., Beilharz M.W., Wines B.D., Hess A.D., Pitha P.M. The MA (p15) and p12 regions of the gag gene are sufficiency for the pathogenicity of the murine AIDS virus. J. Virol. 1993b;67:5989–5999. [PMC free article: PMC238020] [PubMed: 7690416]
  1033. Prasad G., Stoica G., Wong P.K.Y. The role of the thymus in the pathogenesis of hind-limb paralysis induced by ts1, a mutant of Moloney murine leukemia virus-TB. Virology. 1989;169:332–340. [PubMed: 2784929]
  1034. Prendergast G.C., Lawe D., Ziff E.B. Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and Ras cotransformation. Cell. 1991;65:395–407. [PubMed: 1840505]
  1035. Pullen A., Wade T., Marrack P., Kappler J. Identification of the region of the T cell receptor β chain that interacts with the self-superantigen Mls-1a. Cell. 1990;61:1365–1374. [PubMed: 1694725]
  1036. Pullen A.M., Bill J., Kubo R.T., Marrack P., Kappler J.W. Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor Vβ J. Exp. Med. 1991;173:1183–1192. [PMC free article: PMC2118855] [PubMed: 1902503]
  1037. Pullen A.M., Choi Y., Kushnir E., Kappler J., Marrack P. The open reading frames in the 3′ long terminal repeats of several mouse mammary tumor virus integrants encode Vβ3-specific superantigens. J. Exp. Med. 1992;175:41–47. [PMC free article: PMC2119085] [PubMed: 1309854]
  1038. Purchase H.G., Gilmore D.G., Romero C.H., Okazaki W. Post infection genetic resistance to avian lymphoid leukosis resides in a B target cell. Nature. 1977;270:61–62. [PubMed: 200849]
  1039. Qiu F.H., Ray P., Brown K., Barker P.E., Jhanwar S., Ruddle F.H., Besmer P. Primary structure of c-kit: Relationship with the CSF-1/PDGF receptor kinase family—Oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J. 1988;7:1003–1011. [PMC free article: PMC454427] [PubMed: 2456920]
  1040. Quakenbush S.L., Donahue P.R., Dean G.A., Myles M.H., Ackley C.D., Cooper M.D., Mullins J.I., Hoover E.A. Lymphocyte subset alterations and viral determinants of immunodeficiency disease induction by the feline leukemia virus FeLV-FAIDS. J. Virol. 1990;64:5465–5474. [PMC free article: PMC248598] [PubMed: 1976822]
  1041. Querat G., Barban V., Sauze N., Filippi P., Vigne R., Russo P., Vitu C. Highly lytic and persistent lentiviruses naturally present in sheep with progressive pneumonia are genetically distinct. J. Virol. 1984;52:672–679. [PMC free article: PMC254572] [PubMed: 6092689]
  1042. Querat G., Barban V., Sauze N., Vigne R., Payne A., York D., DeVilliers E.M., Verweord D.W. Characteristics of a novel lentivirus derived from South African sheep with pulmonary adenocarcinoma (jaagsiekte). Virology. 1987;158:158–167. [PubMed: 2437695]
  1043. Quint W., Boelens W., Van Wezenbeek P., Robanus Maandag E., Berns A. Generation of AKR mink cell focus-forming virus: Nucleotide sequence of the 3′ end of a somatically acquired AKR-MCF. Virology. 1984;136:425–434. [PubMed: 6087552]
  1044. Rabbitts P.H., Watson J.W., Lamond A., Forster A., Stinson M.A., Evan G., Fischer W., Atherton E., Shepard M.A., Rabbitts T.H. Metabolism of c-myc gene products: c-myc mRNA and protein expression in the cell cycle. EMBO J. 1985;4:2009–2015. [PMC free article: PMC554455] [PubMed: 4065102]
  1045. Rabbitts T.H. Chromosomal translocations in human cancer. Nature. 1994;372:143–149. [PubMed: 7969446]
  1046. Rabbitts T.H., Boehm T. Structural and functional chimerism results from chromosomal translocation in lymphoid tumors. Adv. Immunol. 1991;50:119–146. [PubMed: 1950795]
  1047. Radke K., Beug H., Kornfeld S., Graf T. Transformation of both erythroid and myeloid cells by E26, an avian leukemia virus that contains the myb gene. Cell. 1982;31:643–653. [PubMed: 6297778]
  1048. Raines M.A., Lewis W.G., Crittenden L.B., Kung H.J. c-erbB activation in avian leukosis virus-induced erythroblastosis: Clustered integration sites and the arrangement of provirus in the c-erbB alleles. Proc. Natl. Acad. Sci. 1985;82:2287–2291. [PMC free article: PMC397542] [PubMed: 2986110]
  1049. Raines M.A., Maihle N.J., Moscovici C., Crittenden L., Kung H.-J. Mechanism of c-erbB transduction: Newly released transducing viruses retain poly(A) tracts of erbB transcripts and encode C-terminally intact erbB proteins. J. Virol. 1988a;62:2437–2443. [PMC free article: PMC253402] [PubMed: 2897475]
  1050. Raines M.A., Maihle N.J., Moscovici C., Moscovici M.G., Kung H.-J. Molecular characterization of three erbB transducing viruses generated during avian leukosis virus-induced erythroleukemia: Extensive internal deletion near the kinase domain activates the fibrosarcoma- and hemangioma-inducing potentials of erbB. J. Virol. 1988b;62:2444–2452. [PMC free article: PMC253403] [PubMed: 2836624]
  1051. Rapp U.R., Reynolds F.H., Stephenson J.R. New mammalian transforming retrovirus: Demonstration of a polyprotein gene product. J. Virol. 1983a;45:914–924. [PMC free article: PMC256497] [PubMed: 6300462]
  1052. Rapp U.R., Goldsborough M.D., Mark G.E., Bonner T.I., Groffen J., Reynolds F.H. Jr., Stephenson J.R. Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus. Proc. Natl. Acad. Sci. 1983b;80:4218–4222. [PMC free article: PMC384008] [PubMed: 6308607]
  1053. Rasheed S., Gardner M.G., Huebner R.J. In vitro isolation of stable rat sarcoma viruses. Proc. Natl. Acad. Sci. 1978;75:2972–2976. [PMC free article: PMC392689] [PubMed: 208081]
  1054. Rasheed S., Norman G.L., Heidecker G. Nucleotide sequence of the Rasheed rat sarcoma virus oncogene: New mutations. Science. 1983;221:155–157. [PubMed: 6344220]
  1055. Rasheed S., Barbacid M., Aaronson S.A., Gardner M.B. Origin and biological properties of a new feline sarcoma virus. Virology. 1982;117:238–244. [PubMed: 6175084]
  1056. Rassart E., Shang M., Boie Y., Jolicoeur P. Studies on emerging radiation leukemia virus variants in C57BL/Ka mice. J. Virol. 1986;58:96–106. [PMC free article: PMC252881] [PubMed: 3005663]
  1057. Ratner L. Regulation of expression of the c-sis proto-oncogene. Nucleic Acids Res. 1989;17:4101–4155. [PMC free article: PMC317922] [PubMed: 2740212]
  1058. Ratner L., Philpott T., Trowbridge D.B. Nucleotide sequence analysis of isolates of human T-lymphotropic virus type 1 of diverse geographical origins. AIDS Res. Hum. Retroviruses. 1991;7:923–941. [PubMed: 1760230]
  1059. Rauscher F.J. A virus-induced disease of mice characterized by erythrocytopoiesis and lymphoid leukemia. J. Natl. Cancer Inst. 1962;29:515–543. [PubMed: 14490596]
  1060. Rechavi G., Givol D., Canaani E. Activation of a cellular oncogene by DNA rearrangement: Possible involvement of an IS-like element. Nature. 1982;300:607–611. [PubMed: 6292737]
  1061. Reddy E.P., Lipman D., Anderson P.R., Tronick S.R., Aaronson S.A. Nucleotide sequence analysis of the BALB/c murine sarcoma virus transforming gene. J. Virol. 1985;53:984–987. [PMC free article: PMC254738] [PubMed: 2983103]
  1062. Reeves W.C., Saxinger C., Brenes M.M., Quinoz E., Hoh M., Clark J., Holt C., Gallo R., Blattner W.A. Human T-cell lymphotropic virus type I (HTLV-I) and risk factors in metropolitan Panama. Am. J. Epidemiol. 1988;127:532–539. [PubMed: 2893539]
  1063. Reichman C.T., Mayer B.J., Keshav S., Hanafusa H. The product of the cellular crk gene consists primarily of SH2 and SH3 regions. Cell Growth Differ. 1992;3:451–460. [PubMed: 1329926]
  1064. Reicin A., Yang J.Q., Marcu K.B., Fleissner E., Koehne C.F., O'Donnell P.V. Deregulation of the c-myc oncogene in virus-induced thymic lymphomas of AKR/J mice. Mol. Cell. Biol. 1986;6:4088–4092. [PMC free article: PMC367175] [PubMed: 3025631]
  1065. Reidel N., Hoover E.A., Dornsife R.E., Mullins J.I. Pathogenic and host range determinants of the feline aplastic anemia retrovirus. Proc. Natl. Acad. Sci. 1988;85:2758–2762. [PMC free article: PMC280078] [PubMed: 2833751]
  1066. Reidel N., Hoover E.A., Gasper P.W., Nicolson M.O., Mullins J.I. Molecular analysis and pathogenesis of the feline aplastic anemia retrovirus, FeLV-C-Sarma. J. Virol. 1986;60:242–250. [PMC free article: PMC253922] [PubMed: 3018287]
  1067. Reinhart T.A., Ghost A.K., Hoover E.A., Mullins J.I. Distinct superinfection properties yet similar receptor utilization by cytopathic and noncytopathic feline leukemia viruses. J. Virol. 1993;68:6767–6769. [PMC free article: PMC237913] [PubMed: 8394443]
  1068. Reitz M.S. Jr., Popovic M., Haynes B.F., Clark S.C., Gallo R.C. Relatedness by nucleic acid hybridization of new isolates of human T-cell leukemia-lymphoma virus (HTLV) and demonstration of provirus in uncultured leukemic blood cells. Virology. 1983;126:688–692. [PubMed: 6602415]
  1069. Ren R., Ye Z.S., Baltimore D. Abl protein selects the Crk adapter as a substrate using SH3-binding sites. Genes Dev. 1994;8:783–795. [PubMed: 7926767]
  1070. Renjifo B., Borrero I., Essex M. Tax mutation associated with tropical spastic paraparesis/Human T-cell leukemia virus type I-associated myelopathy. J. Virol. 1995;69:2611–2616. [PMC free article: PMC188940] [PubMed: 7884912]
  1071. Reth M. Immunodeficiency. Trapping the nude mouse gene. Curr. Biol. 1995;5:18–20. [PubMed: 7697339]
  1072. Reynolds A.B., Vila J., Lansing T.J., Potts W.M., Weber M.J., Parsons J.T. Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus. EMBO J. 1987;6:2359–2364. [PMC free article: PMC553640] [PubMed: 2822389]
  1073. Reynolds F.H. Jr., Sacks T.L., Deobagkar D.N., Stephenson J.R. Cells nonproductively transformed by Abelson murine leukemia virus express a high molecular weight polyprotein containing structural and nonstructural components. Proc. Natl. Acad. Sci. 1978;75:3974–3978. [PMC free article: PMC392912] [PubMed: 211510]
  1074. Rice N.R., Lequarre A.S., Casey J.W., Lahn S., Stephens R.M., Edwards J. Viral DNA in horses infected with equine infectious anemia virus. J. Virol. 1989;63:5194–5200. [PMC free article: PMC251183] [PubMed: 2555550]
  1075. Richardson M.P., Gilmore T.D. v-Rel is an inactive member of the Rel family of transcriptional activating proteins. J. Virol. 1991;65:3122–3130. [PMC free article: PMC240968] [PubMed: 1903456]
  1076. Rigby M.A., Pojko J.L., Stewart M.A., Kociba G.J., Cheney C.M., Rezanka L.J., Mathes L.E., Hartke J.R., Jarrett O., Neil J.C. Partial dissociation of subgroup C phenotype and in vivo behaviors in feline leukaemia viruses with chimeric envelope genes. J. Gen. Virol. 1992;73:2839–2847. [PubMed: 1331290]
  1077. Risser R., Kaehler D., Lamph W.W. Different genes control the susceptibility of mice to Moloney or Abelson murine leukemia viruses. J. Virol. 1985;55:547–553. [PMC free article: PMC255004] [PubMed: 2991579]
  1078. Risser R., Potter M., Rowe W.P. Abelson virus-induced lymphomagenesis in mice. J. Exp. Med. 1978;148:714–726. [PMC free article: PMC2185010] [PubMed: 702054]
  1079. Robbins J., Blondel B.J., Gallahan D., Callahan R. Mouse mammary tumor gene Int3: A member of the notch gene family transforms mammary epithelial cells. J. Virol. 1992;66:2594–2599. [PMC free article: PMC289064] [PubMed: 1312643]
  1080. Robert-Guroff M., Nakao Y., Notake K., Ito Y., Sliski A., Gallo R.C. Natural antibodies to human retrovirus HTLV in a cluster of Japanese patients with adult T cell leukemia. Science. 1982;215:975–978. [PubMed: 6760397]
  1081. Robinson F.R., Twiehaus M.J. Isolation of the avian reticuloendotheliosis virus (strain T). Avian Dis. 1974;18:278–288. [PubMed: 4828587]
  1082. Robinson H.L., Gagnon G.C. Patterns of proviral insertion and deletion in avian leukosis virus-induced lymphomas. J. Virol. 1986;57:28–36. [PMC free article: PMC252695] [PubMed: 3001351]
  1083. Robinson H.L., Miles B.D. Avian leukosis virus-induced osteopetrosis is associated with the persistent synthesis of viral DNA. Virology. 1985;141:130–143. [PubMed: 2579505]
  1084. Robinson H.L., Reinsch S.S., Shank P.R. Sequences near the 5′ long terminal repeat of avian leukosis viruses determine the ability to induce osteopetrosis. J. Virol. 1986;59:45–59. [PMC free article: PMC253036] [PubMed: 2423704]
  1085. Robinson H.L., Astrin S.M., Senior A.M., Salazar F.H. Host susceptibility to endogenous viruses: Defective glycoprotein-expressing proviruses interfere with infections. J. Virol. 1981;40:745–751. [PMC free article: PMC256686] [PubMed: 6275116]
  1086. Robinson H.L., Blais B.M., Tsichlis P.N., Coffin J.M. At least two regions of the viral genome determine the oncogenic potential of avian leukosis viruses. Proc. Natl. Acad. Sci. 1982;79:1225–1229. [PMC free article: PMC345934] [PubMed: 6280174]
  1087. Robinson H.L., Miles B.D., Catalano D.E., Briles W.E., Crittenden L.B. Susceptibility to erbB-induced erythroblastosis is a dominant trait of 151 chickens. J. Virol. 1985;55:617–622. [PMC free article: PMC255023] [PubMed: 2991584]
  1088. Robinson H.L., Tracy S.E., Nair N., Sian-Taglienti C., Gamett D.C. Characterization of an angiosarcoma-inducing mutation in the erbB oncogene. Oncogene. 1992a;7:2025–2030. [PubMed: 1408143]
  1089. Robinson H.L., Foster R.G., Blais B.P., Reinsch S.S., Newstein M., Shank P.R. 5′ avian leukosis virus sequences and osteopetrotic potential. Virology. 1992b;190:866–871. [PubMed: 1325711]
  1090. Rodgers-Johnson P.E., Ono S.G., Asher D.M., Gibbs C.J. Jr. Tropical spastic paraparesis and HTLV-I myelopathy: Clinical features and pathogenesis. Res. Publ. Assoc. Res. Nerv. Ment. Dis. 1990;68:117–130. [PubMed: 2183307]
  1091. Rodgers-Johnson P.E., Gajdusek D.C., Morgan O., Zaninovic V., Sarin P.S., Graham D.S. HTLV-I and HTLV-III antibodies and tropical spastic paraparesis. Lancet. 1985;II:1247–1248. [PubMed: 2866324]
  1092. Rodgers-Johnson P.E., Garruto R., Gajdusek D.C., Mora C., Zaninovic V., St. Morgan O. Tropical spastic paraparesis: Evidence for the etiological role of human T-cell lymphotropic virus type I in endemic foci in Jamaica and Columbia. Ann. Neurol. 1987;22:116–117.
  1093. Roelink H., Wagenaar E., Nusse R. Amplification and proviral activation of several Wnt genes during progression and clonal variation of mouse mammary tumors. Oncogene. 1992;7:487–492. [PubMed: 1549363]
  1094. Roelink H., Wagenaar E., Lopes da Silva S., Nusse R. Wnt3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to Int1/Wnt1 and is normally expressed in mouse embryos and adult brain. Proc. Natl. Acad. Sci. 1990;87:4519–4523. [PMC free article: PMC54147] [PubMed: 2162045]
  1095. Rohdewohld H., Weiher H., Reik W., Jaenisch R., Breindl M. Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites. J. Virol. 1987;61:336–343. [PMC free article: PMC253954] [PubMed: 3027365]
  1096. Rohn J., Overbaugh J. In vivo selection of long terminal repeat alterations in feline leukemia virus-induced thymic lymphomas. Virology. 1995;206:661–665. [PubMed: 7831823]
  1097. Rohn J., Linenberger M.L., Hoover E.A., Overbaugh J. Evolution of feline leukemia virus variant genomes with insertions, deletions, and defective envelope genes in infected cats with tumors. J. Virol. 1994;68:2458–2467. [PMC free article: PMC236723] [PubMed: 8139030]
  1098. Rohrschneider L.R., Najita L.M. Detection of the v-abl gene product at cell-substratum contact sites in Abelson murine leukemia virus-transformed fibroblasts. J. Virol. 1984;51:547–552. [PMC free article: PMC254471] [PubMed: 6086963]
  1099. Rojko J.L., Cheney C.M., Gaspar P.W., Hamilton K.L., Hoover E.A., Mathes L.F., Kociba G.J. Infectious feline leukemia virus is erythrosuppressive in vitro. Leuk. Res. 1986;10:1193–1199. [PubMed: 3022080]
  1100. Roman G.C., Osame M. Identity of HTLV-I-associated tropical spastic paraparesis and HTLV-I-associated myelopathy. Lancet. 1988;I:651. [PubMed: 2894583]
  1101. Rommelaere J.H., Donis-Keller H., Hopkins N. RNA sequencing provides evidence for allelism of determinants of the N-, B- or NB tropism of murine leukemia viruses. Cell. 1979;16:43–50. [PubMed: 217545]
  1102. Rosadio R.H., Sharp J.M., Lairmore M.D., Dahlberg J.E., DeMartini J.C. Lesions and retroviruses associated with naturally occurring ovine pulmonary carcinoma (sheep pulmonary adenomatosis). Vet. Pathol. 1988;25:58–66. [PubMed: 2830697]
  1103. Rosen C.A., Haseltine W.A., Lenz J., Ruprecht R., Cloyd M.W. Tissue selectivity of murine leukemia virus infection is determined by long terminal repeat sequences. J. Virol. 1985;55:862–866. [PMC free article: PMC255076] [PubMed: 2991605]
  1104. Rosenberg N., Baltimore D. The effect of helper virus on Abelson virus-induced transformation of lymphoid cells. J. Exp. Med. 1978;147:1126–1141. [PMC free article: PMC2184241] [PubMed: 206646]
  1105. Rosenblatt J.D., Golde D.W., Wachsman W., Jacobs A., Schmidt G., Quan S., Gasson J.C., Chen I.S.Y. A second HTLV-II isolate associated with atypical hairy-cell leukemia. N. Engl. J. Med. 1986;315:372–375. [PubMed: 3016537]
  1106. Rosenblatt J.D., Giorgi J.V., Golde D.W., Ben Eraza J., Wu A., Winberg C.D., Glaspy J., Wachsman W., Chen I.S.Y. Integrated HTLV-II genome in CD8 T-cells from a patient with “atypical” hairy-cell leukemia: Evidence for distinct B- and T-cell proliferative disorders. Blood. 1988;71:363–366. [PubMed: 2827811]
  1107. Rosson D., Dugan D., Reddy E.P. Aberrant splicing events that are induced by proviral integration: Implications for myb oncogene activation. Proc. Natl. Acad. Sci. 1987;84:3171–3175. [PMC free article: PMC304830] [PubMed: 3033638]
  1108. Rous P. A sarcoma of the fowl transmissible by an agent separable from the tumor cells. J. Exp. Med. 1911;13:397–411. [PMC free article: PMC2124874] [PubMed: 19867421]
  1109. Roussel M.F., Dowing J.R., Rettenmier C.W., Sherr C.J. A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential. Cell. 1988;55:979–988. [PubMed: 2974321]
  1110. Rowe W.P., Pugh W.E., Hartley J.W. Plaque assay techniques for murine leukemia virus. Virology. 1970;42:1136–1139. [PubMed: 4099080]
  1111. Rovinski B., Monroe D., Peacock J., Mowat M., Bernstein A., Benchimol S. Deletion of 5′ coding sequences of the cellular p53 gene in mouse erythroleukemia: A novel mechanism of oncogene regulation. Mol. Cell. Biol. 1987;7:847–853. [PMC free article: PMC365143] [PubMed: 3547084]
  1112. Roy D.J., Blacklaws B.A., Dalziel R.G., Watt N.J., McConnell I. Nucleotide sequence of EV1, a British isolate of maedi-visna virus. J. Gen. Virol. 1991;72:1893–1903. [PubMed: 1651983]
  1113. Rozakis-Adcock M., Fernley R., Wade S., Pawson T., Bowtel D. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1. Nature. 1993;363:83–85. [PubMed: 8479540]
  1114. Rozakis-Adcock M., McGlade J., Mbamalu G., Pellici G., Daly R., Batzer A., Thomas S., Brugge J., Pellici P.G., Schlessinger J., Pawson T. Association of the SHC and Grb-2/Sem5 Sh2-containing proteins is implicated in activation of the Ras pathway by threonine kinases. Nature. 1992;360:689–692. [PubMed: 1465135]
  1115. Ru M., Shustik C., Rassart E. Graffi murine leukemia virus: Molecular cloning and characterization of the myeloid leukemia-inducing agent. J. Virol. 1993;67:4722–4731. [PMC free article: PMC237858] [PubMed: 8392610]
  1116. Ruben S., Poteat H., Tan T.H., Kawakami K., Roeder R., Haseltine W., Rosen C.A. Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product. Science. 1988;241:89–92. [PubMed: 2838905]
  1117. Ruscetti S., Wolff L. Biological and biochemical differences between variants of spleen focus-forming virus can be localized to a region containing the 3′ end of the envelope gene. J. Virol. 1985;56:717–722. [PMC free article: PMC252641] [PubMed: 2999427]
  1118. Ruscetti S., Davis L., Feild J., Oliff A. Friend murine leukemia virus-induced leukemia is associated with the formation of mink cell focus-inducing viruses and is blocked in mice expressing endogenous mink cell focus-inducing xenotropic viral envelope genes. J. Exp. Med. 1981;154:907–920. [PMC free article: PMC2186461] [PubMed: 6268733]
  1119. Ruscetti S.K., Janesch N.J., Chakraborti A., Sawyer S.T., Hankins W.D. Friend spleen focus-forming virus induces factor independence in an erythropoietin-dependent erythroleukemia cell line. J. Virol. 1990;64:1057–1062. [PMC free article: PMC249217] [PubMed: 2154592]
  1120. Rushlow K.E., Olsen K., Stiegler G., Payne S., Montelaro R.C., Issel C.J. Lentivirus genomic organization: The complete nucleotide sequence of the env gene of region infectious equine anemia virus. Virology. 1986;155:309–321. [PubMed: 2431539]
  1121. Sablitzky F., Jonsson J.I., Cohen B.L., Phillips R.A. High frequency expression of integrated proviruses derived from enhancer trap retroviruses. Cell Growth Differ. 1993;4:451–459. [PubMed: 8373730]
  1122. Sagata N., Watanabe N., Vande Woude G.F., Ikawa Y. The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs. Nature. 1989a;342:512–518. [PubMed: 2531292]
  1123. Sagata N., Daar I., Oskarsson M., Showalter S.D., Vande Woude G.F. The product of the mos proto-oncogene as a candidate “initiator” for oocyte maturation. Science. 1989b;245:643–646. [PubMed: 2474853]
  1124. Sagata N., Oskarsson M., Copeland T., Brumbaugh J., Vande Woude G.F. Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes. Nature. 1988;335:519–525. [PubMed: 2971141]
  1125. Sagata N., Yasunaga T., Tsuzuku-Kawamura J., Ohishi K., Ogawa Y., Ikawa Y. Complete nucleotide sequence of the genome of bovine leukemia virus: Its evolutionary relationship to other retroviruses. Proc. Natl. Acad. Sci. 1985;82:677–681. [PMC free article: PMC397108] [PubMed: 2983308]
  1126. Saito S., Furuki K., Ando Y., Tanigawa T., Kakimoto K., Moriyama I., Ichijo M. Identification of HTLV-I sequence in cord blood mononuclear cells of neonates born to HTLV-I antigen/antibody-positive mothers by polymerase chain reaction. Jpn. J. Cancer Res. 1990;81:890–895. [PMC free article: PMC5918105] [PubMed: 2121690]
  1127. Saji F., Ohashi K., Tokugawa Y., Kamiura S., Azuma C., Tanizawa O. Perinatal infection of human T-lymphotropic virus type I, the etiologic virus of adult T-cell leukemia/lymphoma. DNA amplification of specific human T-lymphotrophic virus type I sequences. Cancer. 1990;66:1933–1937. [PubMed: 2224789]
  1128. Sakai R., Iwanatsu A., Hirano N., Ogawa S., Tanaka T., Mano H., Yazaki Y., Hirai H. A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner. EMBO J. 1994;13:3748–3756. [PMC free article: PMC395286] [PubMed: 8070403]
  1129. Salinovich O., Payne S.L., Montelaro R.C., Hussain K.A., Issel C.J., Schnorr K.L. Rapid emergence of novel antigenic and genetic variants of equine infectious anemia virus during persistent infection. J. Virol. 1986;57:71–80. [PMC free article: PMC252700] [PubMed: 3001367]
  1130. Salmons B., Gunzburg W.H. Current perspective in the biology of mouse mammary tumor virus. Virus Res. 1987;8:81–102. [PubMed: 2823501]
  1131. Salterelli M., Querat G., Konings D.A.M., Vigne R., Clements J.E. Nucleotide sequence and transcriptional analysis of molecular clones of CAEV which generate infectious virus. Virology. 1990;179:347–364. [PubMed: 2171210]
  1132. Samarut J., Gazzolo L. Target cells infected by avian erythroblastosis virus differentiate and become transformed. Cell. 1982;28:921–929. [PubMed: 7094018]
  1133. Sanada I., Tanaka R., Kumagai E., Tsuda H., Nishimura H., Yamaguchi K., Kawano F., Fujiwara H., Takatsuki K. Chromosomal aberrations in adult T cell leukemia: Relationship to the clinical severity. Blood. 1985;65:649–654. [PubMed: 3871643]
  1134. Sap J.A., Munoz A., Schmitt J., Stunnenberg H., Vennstrom B. Repression of transcription mediated by a thyroid hormone response element by the v-erbA oncogene product. Nature. 1989;340:242–244. [PubMed: 2569164]
  1135. Sap J.A., Munoz A., Damm K., Goldberg Y., Ghysdael J., Leutz A., Beug H., Vennstrom B. The c-erb-A protein is a high affinity receptor for thyroid hormone. Nature. 1986;324:635–640. [PubMed: 2879242]
  1136. Sarkar S., Gilmore T.D. Transformation by the v-Rel oncoprotein requires sequences carboxyl-terminal to the Rel homology domain. Oncogene. 1993;8:2245–2252. [PubMed: 8336947]
  1137. Sato H., Okochi K. Transmission of human T-cell leukemia virus (HTLV-I) by blood transfusion: Demonstration of proviral DNA in recipient's blood lymphocytes. Int. J. Cancer. 1986;37:395–400. [PubMed: 3005178]
  1138. Savard P., DesGroseillers L., Rassart E., Poirier Y., Jolicoeur P. Important role of the long terminal repeat of the helper Moloney murine leukemia virus in Abelson virus-induced lymphoma. J. Virol. 1987;61:3266–3275. [PMC free article: PMC255907] [PubMed: 3041046]
  1139. Sawyers C.L. The bcr-abl gene in chronic myelogenous leukaemia. Cancer Sur. 1992;15:37–51. [PubMed: 1451113]
  1140. Saxinger C., Blattner W.A., Levine P.H., Clark J., Biggar R., Hoh M., Moghissi J., Jacobs P., Wilson L., Jacobson R., Crooes R., Strong M., Ansari A.A., Dean A.G., Nkrumah F.K., Mourali N., Gallo R.C. Human T-cell leukemia virus (HTLV-I) antibodies in Africa. Science. 1984;225:1473–1476. [PubMed: 6089348]
  1141. Scher C.D. Effect of pseudotype on Abelson virus and Kirsten sarcoma virus-induced leukemia. J. Exp. Med. 1978;147:1044–1053. [PMC free article: PMC2184244] [PubMed: 206644]
  1142. Scher C.D., Siegler R. Direct transformation of 3T3 cells by Abelson murine leukemia virus. Nature. 1975;253:729–731. [PubMed: 163444]
  1143. Scherdin U., Rhodes K., Breindl M. Transcriptionally active genome regions are preferred targets for retrovirus integration. J. Virol. 1990;64:907–912. [PMC free article: PMC249188] [PubMed: 2296087]
  1144. Schierman L.W., Collins W.M. Influence of the major histocompatibility complex on tumor regression and immunity in chickens. Poult. Sci. 1987;60:812–818. [PubMed: 3306646]
  1145. Schierman L.W., Watanabe D.H., McBride R.A. Genetic control of Rous sarcoma regression in chickens: Linkage with the major histocompatibility complex. Immunogenetics. 1977;5:325–332.
  1146. Schlaepfer D.D., Hanks S.K., Hunter T., van der Geer P. Integrin-mediated signal transduction linked to Ras pathway by Grb2 binding to focal adhesion kinase. Nature. 1994;372:786–791. [PubMed: 7997267]
  1147. Schlessinger J., Bar-Sagi D. Activation of Ras and other signaling pathways by receptor tyrosine kinases. Cold Spring Harbor Symp. Quant. Biol. 1994;59:173–179. [PubMed: 7587067]
  1148. Schroeder C., Gibson L., Nordstrom C., Beug H. The estrogen receptor cooperates with the TGFα receptor (c-erbB) in regulation of chicken erythroid progenitor self-renewal. EMBO J. 1993;12:951–960. [PMC free article: PMC413296] [PubMed: 8458346]
  1149. Schroeder C., Raynoschek C., Fuhrmann U., Damm K., Vennstrom B., Beug H. The v-erbA oncogene causes repression of erythrocyte-specific genes and an immature, aberrant differentiation phenotype in normal erythroid progenitors. Oncogene. 1990;5:1445–1453. [PubMed: 1979159]
  1150. Schwartz M.S., Smith G.H., Medina D. The effect of parity, tumor latency and transplantation on the activation of int loci in MMTV-induced, transplanted C3H mammary pre-neoplasias and their tumors. Int. J. Cancer. 1992;51:805–811. [PubMed: 1351886]
  1151. Schuermann M., Michalides R. A rare common integration site of proviruses of the mouse mammary tumor virus in P-type mammary tumors of mouse strain GR. Virology. 1987;156:229–237. [PubMed: 3027974]
  1152. Schulz T.F., Calabro M.L., Hoad J.G., Carrington C.V., Matutes E., Catovsky D., Weiss R.A. HTLV-1 envelope sequences from Brazil, the Caribbean, and Romania: Clustering of sequences according to geographic origin and variability in an antibody epitope. Virology. 1991;184:483–491. [PubMed: 1716024]
  1153. Seeburg P.H., Colby W.W., Capon D.J., Goeddel D.V., Levinson A.D. Biological properties of human c-Ha-ras1 genes mutated at codon 12. Nature. 1984;312:71–75. [PubMed: 6092966]
  1154. Segre J.A., Nemhauser J.L., Taylor B.A., Nadeau J.H., Lander E.S. Positional cloning of the nude locus: Genetic, physical, and transcription maps of the region and mutations in the mouse and rat. Genomics. 1995;28:549–559. [PubMed: 7490093]
  1155. Seiki M., Hattori S., Yoshida M. Human adult T-cell leukemia virus: Molecular cloning of the provirus DNA and the unique terminal structure. Proc. Natl. Acad. Sci. 1982;79:6899–6902. [PMC free article: PMC347241] [PubMed: 6294664]
  1156. Seiki M., Eddy R., Shows T.B., Yoshida M. Nonspecific integration of the HTLV provirus genome into adult T-cell leukaemia cells. Nature. 1984;309:640–642. [PubMed: 6328324]
  1157. Seiki M., Inoue J.-I., Takeda T., Yoshida M. Direct evidence that p40xl of HTLV-I is a trans-acting transcriptional activator. EMBO J. 1986;5:561–565. [PMC free article: PMC1166799] [PubMed: 3011413]
  1158. Selivanova G., Wiman K.G. P53: A cell cycle regulator activated by DNA damage. Adv. Cancer Res. 1995;66:143–180. [PubMed: 7793313]
  1159. Sellon D.C., Perry S.T., Coggins L., Fuller F.J. Wild-type equine infectious anemia virus replicates in vivo predominantly in tissue macrophages, not in peripheral blood monocytes. J. Virol. 1992;66:5906–5913. [PMC free article: PMC241467] [PubMed: 1382143]
  1160. Sellon R.K., Jordan H.L., Kennedy-Stoskopf S., Tompkins M.B. Feline immunodeficiency virus can be experimentally transmitted via milk during acute maternal infection. J. Virol. 1994;68:3380–3385. [PMC free article: PMC236830] [PubMed: 8151797]
  1161. Sels F.T., Langer S., Schulz A.S., Silver J., Sitbon M., Friedrich R.W. Friend murine leukaemia virus is integrated at a common site in most primary spleen tumours of erythroleukaemic animals. Oncogene. 1992;7:643–652. [PubMed: 1565463]
  1162. Selten G., Cuypers H.T., Berns A. Proviral activation of the putative oncogene Pim1 in MuLV induced T-cell lymphomas. EMBO J. 1985;4:1793–1798. [PMC free article: PMC554419] [PubMed: 2992942]
  1163. Selten G., Cuypers H.T., Zijlstra M., Melief C., Berns A. Involvement of c-myc in MuLV-induced T cell lymphomas in mice: Frequency and mechanisms of activation. EMBO J. 1984;3:3215–3222. [PMC free article: PMC557840] [PubMed: 6098468]
  1164. Selten G., Cuypers H.T., Boelens W., Robanus-Maandag E., Verbeek J., Domen J., Van Beveren C., Berns A. The primary structure of the putative oncogene pim-1 shows extensive homology with protein kinases. Cell. 1986;46:603–611. [PubMed: 3015420]
  1165. Selvey L.A., Morse H.C. III, Granger L.G., Hodes R.J. Preferential expansion and activation of Vβ5+ CD4+ T cells in murine acquired immunodeficiency syndrome. J. Immunol. 1993;151:1712–1722. [PubMed: 8101545]
  1166. Selvey L.A., Morse H.C. III, June C.H., Hodes R.J. Analysis of antigen receptor signaling in B cells from mice with a retrovirus-induced acquired immunodeficiency syndrome. J. Immunol. 1995;154:171–179. [PubMed: 7995937]
  1167. Sentsui H., Kono Y. Phagocytosis of horse erythrocytes treated with equine infectious anemia virus by cultivated horse leukocytes. Arch. Virol. 1987a;95:67–77. [PubMed: 3036046]
  1168. Sentsui H., Kono Y. Complement mediated hemolysis of horse erythrocytes treated with equine infectious anemia virus. Arch. Virol. 1987b;95:53–66. [PubMed: 3036045]
  1169. Sentsui H., Kono Y. Studies on viral-induced anemia in horses infected with EIAV. Jpn J. Vet. Sci. 1988;50:303–311. [PubMed: 3386089]
  1170. Setoguchi M., Higuchi Y., Yoshida S., Nasu N., Miyazaki Y., Akizuki S., Yamamoto S. Insertional activation of N-myc by endogenous Moloney-like murine retrovirus sequences in macrophage cell lines derived from myeloma cell line-macrophage hybrids. Mol. Cell. Biol. 1989;9:4515–4522. [PMC free article: PMC362536] [PubMed: 2555695]
  1171. Shackleford G.M., MacArthur C.A., Kwan H.C., Varmus H.E. Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4. Proc. Natl. Acad. Sci. 1993;90:740–744. [PMC free article: PMC45741] [PubMed: 8380647]
  1172. Sharif M., Privalsky M.L. V-erbA oncogene function in neoplasia correlates with its ability to repress retinoic acid receptor action. Cell. 1991;66:885–893. [PubMed: 1679679]
  1173. Sharp J.M. Sheep pulmonary adenomatosis: A contagious tumour and its causes. Cancer Surv. 1987;6:73–83. [PubMed: 3319134]
  1174. Sharp J.M., Angus K.W., Gray E.W., Scott P.M. Rapid transmission of sheep pulmonary adenomatosis (jaagsiekte) in young lambs. Brief report. Arch. Virol. 1992;78:89–95. [PubMed: 6197047]
  1175. Sheets R.L., Pandey R., Klement V., Grant C.K., Roy-Burman P. Biologically selected recombinants between feline leukemia virus (FeLV) subgroup A and an endogenous FeLV element. Virology. 1992;190:849–855. [PubMed: 1381539]
  1176. Shelton G.H., Linenberger M.L., Grant C.K., Abkowitz J.L. Hematologic manifestations of feline immunodeficiency virus infection. Blood. 1990;76:1104–1109. [PubMed: 2400806]
  1177. Shen-Ong G.L., Wolff L. Moloney murine leukemia virus-induced myeloid tumors in adult BALB/c mice: Requirement of c-myb activation but lack of v-abl involvement. J. Virol. 1987;61:3721–3725. [PMC free article: PMC255984] [PubMed: 2824810]
  1178. Shen-Ong G.L., Morse H.C., Potter M., Mushinski J.F. Two modes of c-myb activation in virus-induced mouse myeloid tumors (published erratum appears in Mol. Cell. Biol. [1986]. 6:2756). Mol. Cell. Biol. 1986;6:380–392. [PMC free article: PMC367527] [PubMed: 3023843]
  1179. Shen-Ong G.L.C., Potter M., Mushinski J.F., Lavu S., Reddy E.P. Activation of the c-myb locus by viral insertional mutagenesis in plasmacytoid lymphosarcomas. Science. 1984;226:1077–1080. [PubMed: 6093260]
  1180. Shi Y., Alin K., Goff S.P. Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity. Genes Dev. 1995;9:2583–2597. [PubMed: 7590237]
  1181. Shibuya M., Hanafusa H. Nucleotide sequence of Fujinami sarcoma virus: Evolutionary relationship of its transforming gene with transforming genes of other sarcoma viruses. Cell. 1982;30:787–795. [PubMed: 6291784]
  1182. Shibuya T., Mak T.W. A host gene controlling early anaemia or polycytheaemia induced by Friend erythroleukaemia virus. Nature. 1982;296:577–579. [PubMed: 6951109]
  1183. Shih D., Carruth L., Anderson M.A., Clements J.E. Involvement of FOS and JUN in the activation of visna virus gene expression in macrophages through an AP-1 site in the viral LTR. Virology. 1992;190:84–91. [PubMed: 1326822]
  1184. Shih T.Y., Williams D.R., Weeks M.O., Maryak J.M., Vass W.C., Scolnick E.M. Comparison of the genomic organization of Kirsten and Harvey sarcoma viruses. J. Virol. 1978;27:45–55. [PMC free article: PMC354139] [PubMed: 211254]
  1185. Shimoyama M. Diagnostic criteria and classification of clinical subtypes of adult T-cell leukemia-lymphoma. A report from the lymphoma study group (1984–1987). Br. J. Haemotol. 1991;79:437. [PubMed: 1751370]
  1186. Shimoyama M., Minato K., Tobinai K., Nagai M., Setoya T., Takenaka T., Ishihara K., Watanabe S., Hoshina H., Miwa M., Kinoshita M., Okabe S., Fukushima N., Inada N. Atypical adult T-cell leukemia-lymphoma: Diverse clinical manifestations of adult T-cell leukemia-lymphoma. Jpn. J. Clin. Oncol. 1983;13:165–188. [PubMed: 6603526]
  1187. Shin S., Steffen D.L. Frequent activation of the lck gene by promoter insertion and aberrant splicing in murine leukemia virus-induced rat lymphomas. Oncogene. 1993;8:141–149. [PubMed: 8423992]
  1188. Siebelink K.H.J., Chu I.-H., Rimmelzwaan G.F., Weijer K., Herwijnen R., Van Knell P., Egberink H.F., Bosch M.L., Osterhaus A.D.M.E. Feline immunodeficiency virus (FIV) infection in the cat as a model for HIV infections in man: FIV induced impairment of immune function. AIDS. 1991;6:1373–1378. [PubMed: 1964059]
  1189. Siekevitz M., Feinberg M.B., Holbrook N., Wong-Staal F., Greene W.C. Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene of human T-cell leukemia virus, type I. Proc. Natl. Acad. Sci. 1987;84:5389–5393. [PMC free article: PMC298861] [PubMed: 3037548]
  1190. Sigurdsson B., Palsson P.A., Grimsson H. Visna, a demyelinating transmissible disease of sheep. J. Neuropathol. Exp. Neurol. 1957;16:389–403. [PubMed: 13439402]
  1191. Sigurdsson B., Thormar H., Palsson P.A. Cultivation of visna virus in tissue culture. Arch. Gesamte Virusforsch. 1960;10:368–381. [PubMed: 13776693]
  1192. Silver J., Fredrickson T.N. A new gene that controls the type of leukemia induced by Friend murine leukemia virus. J. Exp. Med. 1983;158:493–505. [PMC free article: PMC2187339] [PubMed: 6577128]
  1193. Silver J., Kozak C. Common proviral integration region on mouse chromosome 7 in lymphomas and myelogenous leukemias induced by Friend murine leukemia virus. J. Virol. 1986;57:526–533. [PMC free article: PMC252765] [PubMed: 3456057]
  1194. Simard C., Huang M., Jolicoeur P. Murine AIDS is initiated in the lymph nodes draining the site of inoculation, and the infected B cells influence T cells located at a distance, in noninfected organs. J. Virol. 1994;68:1903–1912. [PMC free article: PMC236652] [PubMed: 8107250]
  1195. Simard C., Huang M., Jolicoeur P. Establishment of leukemic T-cell lines from mice inoculated with the MAIDS defective virus. Virology. 1995;206:555–563. [PubMed: 7831810]
  1196. Simon M.C., Smith R.E., Hayward W.S. Mechanisms of oncogenesis by subgroup F avian leukosis viruses. J. Virol. 1984;52:1–8. [PMC free article: PMC254481] [PubMed: 6207306]
  1197. Smith R.E. Avian osteopetrosis. Curr. Top. Microbiol. Immunol. 1982;101:75–94. [PubMed: 6303704]
  1198. Snyder H.W. Jr., Singhal M.C., Zuckerman E.E., Hardy W.D. Jr. Isolation of a new feline sarcoma virus (HZ-1-FeSV), Biochemical and immunological characterization of its translation product. Virology. 1984;132:205–210. [PubMed: 6320533]
  1199. Snyder S.P., Theilen G.H. Transmissible feline fibrosarcoma. Nature. 1969;221:1074–1075. [PubMed: 5774407]
  1200. Sodora D.L., Shpaer E.G., Kitchell B.E., Dow S.W., Hoover E.A., Mullins J.I. Identification of three feline immunodeficiency virus (FIV) env gene subtypes and comparison of the FIV and human immunodeficiency virus type 1 evolutionary patterns. J. Virol. 1994;68:2230–2238. [PMC free article: PMC236699] [PubMed: 8139008]
  1201. Sodroski J., Rosen C., Goh W.C., Haseltine W. A transcriptional activator protein encoded by the x-lor region of human T-cell leukemia virus. Science. 1985;228:1430–1434. [PubMed: 2990028]
  1202. Soeharsono S., Hartaningsih N., Soetrisno M., Kartayadnya G., Wilcox G.E. Studies of experimental Jembrana disease in Bali cattle. I. Transmission and persistence of the infectious agent in ruminants and pigs, and resistance of recovered cattle to reinfection. J. Comp. Pathol. 1990;103:49–59. [PubMed: 2394846]
  1203. Soesanto M., Soeharsono S., Budiantono A., Sulistyana K., Tenaya M., Wilcox G.E. Studies on experimental Jembrana disease in Bali cattle. II. Clinical signs and haematological changes. J. Comp. Pathol. 1990;103:61–71. [PubMed: 2394847]
  1204. Sohn C.C., Blayney D.W., Misset J.L., Mathe G., Flandrin G., Moran E.M., Jensen F.C., Winberg C.D., Rappaport H. Leukopenic chronic T-cell leukemia mimicking hairy cell leukemia: Association with human retroviruses. Blood. 1986;67:949–956. [PubMed: 3006837]
  1205. Sola B., Fichelson S., Bordereaux D., Tambourin P.E., Gisselbrecht S. Fim1 and Fim2: Two new integration regions of Friend murine leukemia virus in myeloblastic leukemias. J. Virol. 1986;60:718–725. [PMC free article: PMC288946] [PubMed: 3464762]
  1206. Sola B., Simon D., Mattei M.G., Fichelson S., Bordereaux D., Tambourin P.E., Guenet J.L., Gisselbrecht S. Fim1, Fim2/ c-Fms, and Fim3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectively. J. Virol. 1988;62:3973–3978. [PMC free article: PMC253824] [PubMed: 2902233]
  1207. Solomon J.J., Burmester B.R., Fredrickson T.N. Investigations of lymphoid leukosis infection in genetically similar chicken populations. Avian Dis. 1966;10:477–483. [PubMed: 4291343]
  1208. Sonigo P., Alizon M., Staskus K., Klatzmann D., Cole S., Danos O., Retzel E., Tiollais P., Haase A., Wain-Hobson S. Nucleotide sequence of the visna lentivirus: Relationship to the AIDS virus. Cell. 1985;42:369–382. [PubMed: 2410140]
  1209. Sonstegard R.A. Studies of the etiology and epizootiology of lymphosarcoma in Esox (Esox lucius L. and Esox masquinongy). Prog. Exp. Tumor Res. 1976;20:141–155. [PubMed: 790463]
  1210. Sotirov N. Histone H5 in the immature blood cells of chickens with leukosis induced by avian leukemia virus strain E26. J. Natl. Cancer Inst. 1981;66:1143–1149. [PubMed: 6264195]
  1211. Spaargaren M., Bischoff J.R., McCormick F. Signal transduction by Ras-like GTPases: A potential target for anticancer drugs. Gene Expr. 1995;4:345–356. [PMC free article: PMC6134362] [PubMed: 7549466]
  1212. Speck N.A., Renjifo B., Golemis E., Fredrickson T.N., Hartley J.W., Hopkins N. Mutation of the core or adjacent Lvb elements of the Moloney murine leukemia virus enhancer alters disease specificity. Genes Dev. 1990;4:233–242. [PubMed: 2338244]
  1213. Staal S.P., Hartley J.W., Rowe W.P. Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma. Proc. Natl. Acad. Sci. 1977;74:3065–3067. [PMC free article: PMC431413] [PubMed: 197531]
  1214. Stanley J., Bhaduri L.M., Narayan O., Clements J.E. Topographical rearrangements of visna virus envelope glycoprotein during antigenic drift. J. Virol. 1987;61:1019–1028. [PMC free article: PMC254058] [PubMed: 2434662]
  1215. Stanton V.P. Jr., Nichols D.W., Laudano A.P., Cooper G.M. Definition of the human raf amino-terminal regulatory region by deletion mutagenesis. Mol. Cell. Biol. 1989;9:639–647. [PMC free article: PMC362641] [PubMed: 2710120]
  1216. Staskus K.A., Couch L., Bitterman P., Rezel E.F., Zupancic M., List J., Haase A.T. In situ hybridization of visna virus DNA in tissue sections reveals a reservoir of latently infected cells. Microb. Pathog. 1991a;11:67–76. [PubMed: 1665538]
  1217. Staskus K.A., Retzel E.F., Lewis E.D., Silsby J.L., St. Cyr S., Rank J.M., Wietgrefe S.W., Haase A.T., Cook R., Fast D., Geiser P.T., Harty J.T., Kona S.H., Lahti C.J., Neufeld T.P., Porter T.E., Shoop E., Zachow K.R. Isolation of replication-competent molecular clones of visna virus. Virology. 1991b;181:228–240. [PubMed: 1847257]
  1218. Stavnezer E., Gerhard D.S., Biari R.C., Balzas I. Generation of transforming viruses in cultures of chicken fibroblasts infected with an avian leukosis virus. J. Virol. 1981;39:920–934. [PMC free article: PMC171326] [PubMed: 6169846]
  1219. St. Cyr Coats K., Pruett S.B., Nash J.W., Cooper C.R. Bovine immunodeficiency virus: Incidence of infection in Mississippi dairy cattle. Vet. Microbiol. 1994;42:181–189. [PubMed: 7886931]
  1220. Steeves R.A., Bennett M., Mirand E.A., Cudkowicz G. Genetic control by the W locus of susceptibility to (Friend) spleen focus-forming virus. Nature. 1968;218:372–374. [PubMed: 4870185]
  1221. Steffen D. Proviruses are adjacent to c-myc in some murine leukemia virus-induced lymphomas. Proc. Natl. Acad. Sci. 1984;81:2097–2101. [PMC free article: PMC345444] [PubMed: 6326104]
  1222. Steffen D., Weinberg R.A. The integrated genome of murine leukemia virus. Cell. 1978;15:1003–1010. [PubMed: 728982]
  1223. Stewart M.A., Warnock M., Wheeler A., Wilkie N., Mullins J.I., Onions D.E., Neil J.C. Nucleotide sequences of a feline leukemia virus subgroup A envelope gene and long terminal repeat and evidence for the recombinational origin of subgroup B viruses. J. Virol. 1986;58:825–834. [PMC free article: PMC252989] [PubMed: 3009890]
  1224. Stocking C., Kollek R., Bergholz U., Ostertag W. Long terminal repeat sequences impart hematopoietic transformation properties to the myeloproliferative sarcoma virus. Proc. Natl. Acad. Sci. 1985;82:5746–5750. [PMC free article: PMC390629] [PubMed: 2994046]
  1225. Stocking C., Kollek R., Bergholz U., Ostertag W. Point mutations in the U3 region of the long terminal repeat of Moloney murine leukemia virus determine disease specificity of the myeloproliferative sarcoma virus. Virology. 1986;153:145–149. [PubMed: 3016984]
  1226. Stocking C., Loliger C., Kawai M., Suciu S., Gough N., Ostertag W. Identification of genes involved in growth autonomy of hematopoietic cells by analysis of factor-independent mutants. Cell. 1988;53:869–879. [PubMed: 2838175]
  1227. Stokoe D., MacDonald S.G., Cadwallader K., Symons M., Hancock J.F. Activation of Raf as a result of recruitment to the plasma membrane. Science. 1994;264:1463–1467. [PubMed: 7811320]
  1228. Storch T.G., Arnstein P., Manohar V., Leiseron W.M., Chused T.M. Proliferation of infected lymphoid precursors before Moloney murine leukemia virus-induced T-cell lymphoma. J. Natl. Cancer Inst. 1985;74:137–143. [PubMed: 3871491]
  1229. Stoye J.P., Moroni C., Coffin J.M. Virological events leading to spontaneous AKR thymomas. J. Virol. 1991;65:1273–1285. [PMC free article: PMC239902] [PubMed: 1847454]
  1230. Stromberg K., Benveniste R.E., Arthur L.O., Rabin H., Griffths W.E. Jr., Ochs H.D., Morton W.R., Tsai C. Characterization of exogenous type D retrovirus from a fibroma of a macaque with simian AIDS and fibromatosis. Science. 1984;224:289–292. [PubMed: 6200929]
  1231. Suga T., Kameyama T., Kinoshita T., Shimotohno K., Matsumua M., Tanaka H., Kushida S., Ami Y., Uchida M., Uchida K., Miwa M. Infection of rats with HTLV-I: A small animals model for HTLV-I carriers. Int. J. Cancer. 1991;49:764–769. [PubMed: 1682281]
  1232. Sugamura K., Fujii M., Kannagi M., Sadamori M., Takeuchi M., Hinuma Y. Cell surface phenotype and expression of viral antigens of various human cell lines carrying human T-cell leukemia virus. Int. J. Cancer. 1984;34:221–228. [PubMed: 6088403]
  1233. Sugita K., Gutkind J.S., Katamine S., Kawakami T., Robbins K.C. The actin domain of Gardner-Rasheed feline sarcoma virus inhibits kinase and transforming activities. J. Virol. 1989;63:1715–1720. [PMC free article: PMC248428] [PubMed: 2538651]
  1234. Suzuki S. Fv-4: A new gene affecting the splenomegaly induction by Friend leukemia virus. Jpn J. Exp. Med. 1975;45:473–478. [PubMed: 1232464]
  1235. Suzuki S., Axelrad A.A. Fv2 locus controls the proportion of erythropoietic progenitor cells (BFU-E) synthesizing DNA in normal mice. Cell. 1980;19:225–236. [PubMed: 7357602]
  1236. Sveda M.M., Soeiro R. Host restriction of Friend leukemia virus: Synthesis and integration of the provirus. Proc. Natl. Acad. Sci. 1976;73:2356–2360. [PMC free article: PMC430564] [PubMed: 1065886]
  1237. Svoboda J., Machala O., Hilgert I. Demonstration of the absence of infectious Rous virus in rat tumor XC, whose structurally intact cells produce Rous sarcoma when transferred to chicks. Folia Biol. 1963;9:77–81. [PubMed: 13984556]
  1238. Swardson C.J., Kociba G.J., Perryman L.E. Effects of equine infectious anemia virus on hematopoietic progenitors in vitro. Am. J. Vet. Res. 1992;53:1176–1179. [PubMed: 1323227]
  1239. Swarz J.R., Brooks B.R., Johnson R.T. Spongiform polioencephalomyelopathy caused by a murine retrovirus. II. Ultrastructural localization of virus replication and spongiform changes in the central nervous system. Neuropathol. Appl. Neurobiol. 1981;7:365–380. [PubMed: 6272148]
  1240. Sweet R.W., Yokoyama S., Kamata T., Feramisco J.R., Rosenberg M., Gross M. The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity. Nature. 1984;311:273–275. [PubMed: 6148703]
  1241. Swift R.A., Boerkoel C., Ridgway A., Fujita D.J., Dodgson J.B., Kung H.J. B-lymphoma induction by reticuloendotheliosis virus: Characterization of a mutated chicken syncytial virus provirus involved in c-myc activation. J. Virol. 1987;61:2084–2090. [PMC free article: PMC254228] [PubMed: 3035210]
  1242. Symonds G., Hatshorn A., Kennewell A., O'Mara M.-A., Bruskin A., Bishop J.M. Transformation of murine myelomonocytic cells by myc: Point mutations in v-myc contribute synergistically to transforming potential. Oncogene. 1989;4:285–294. [PubMed: 2649846]
  1243. Szurek P.F., Yuen P.H., Jerzy R., Wong P.K. Identification of point mutations in the envelope gene of Moloney murine leukemia virus TB temperature-sensitive paralytogenic mutant ts1: Molecular determinants for neurovirulence. J. Virol. 1988;62:357–360. [PMC free article: PMC250539] [PubMed: 3334748]
  1244. Tajima K. The 4th nationwide study of adult T-cell leukemia/lymphoma (ATL) in Japan: Estimates of risk of ATL and its geographical and clinical features. Int. J. Cancer. 1990;45:237–243. [PubMed: 2303290]
  1245. Tajima K., Tominaga S., Suchi T., Kawagoe T., Komoda H., Hinuma Y., Oda T., Fujita K. Epidemiological analysis of the distribution of antibody to adult T-cell leukemia-virus associated antigen: Possible horizontal transmission of adult T-cell leukemia virus. Gann. 1982;73:893–901. [PubMed: 6984401]
  1246. Talbot R.L., Sprager E.E., Lovelace K.M., Fitch W.M., Pedersen N.C., Luciw P.A., Elder J.H. Nucleotide sequence and genomic organization of feline immunodeficiency virus. Proc. Natl. Acad. Sci. 1989;86:5743–5747. [PMC free article: PMC297706] [PubMed: 2762293]
  1247. Tan J.C., Nocka K., Ray P., Traktman P., Besmer P. The dominant W42 spotting phenotype results from a missense mutation in the c-kit receptor tyrosine kinase. Science. 1990;247:209–212. [PubMed: 1688471]
  1248. Tanaka A., Takahashi C., Yamaoka S., Nosaka T., Maki M., Hatanaka M. Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro. Proc. Natl. Acad. Sci. 1990;87:1071–1075. [PMC free article: PMC53412] [PubMed: 2300570]
  1249. Tanaka S., Morishita T., Hashimoto Y., Hattori S., Kakamura S., Shibuya M., Matsuoka K., Takenawa T., Kurata T., Nagashima K., Matsuda M. C3G, A guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins. Proc. Natl. Acad. Sci. 1994;91:3443–3447. [PMC free article: PMC43593] [PubMed: 7512734]
  1250. Tang Y., Fredrickson T.N., Chattopadhyay S.K., Hartley J.W., Morse H.C. III. Lymphomas in mice retrovirus-induced immunodeficiency. Curr. Top. Microbiol. Immunol. 1992;182:395–398. [PubMed: 1490377]
  1251. Tanigawa T., Robb L., Green A.R., Begley C.G. Constitutive expression of the putative transcription factor scl associated with proviral insertion in the myeloid leukemic cell line WEHI-3D. Cell Growth Differ. 1994;5:557–561. [PubMed: 8086334]
  1252. Taniguchi A., Ishida T., Konno A., Washizu T., Tomoda I. Altered mitogen response of peripheral blood lymphocytes in different stages of feline immunodeficiency virus. Jpn. J. Vet. Sci. 1990;52:513–518. [PubMed: 2166850]
  1253. Temin H.M., Rubin H. Characteristics of an assay for Rous sarcoma virus and Rous sarcoma cells in tissue culture. Virology. 1958;17:669–688. [PubMed: 13616179]
  1254. ten Hoeve J., Morris C., Heisterkamp N., Groffen J. Isolation and chromosomal localization of CRKL, a human crk-like gene. Oncogene. 1993;8:2469–2474. [PubMed: 8361759]
  1255. Terry A., Callanan J.J., Fulton R., Jarrett O., Neil J.C. Molecular analysis of tumours from feline immunodeficiency virus (FIV)-infected cats: An indirect role for FIV? Int. J. Cancer. 1995;61:227–232. [PubMed: 7705953]
  1256. Testa N.G., Onions D., Jarrett O., Frassoni F., Eliason J.F. Haematopoietic colony formation (BFU-E, GM-CFC) during the development of pure red cell hypoplasia induced in the cat by feline leukaemia virus. Leuk. Res. 1983;7:103–116. [PubMed: 6304428]
  1257. Thiesen H.-J., Bosze Z., Henry L., Charnay P. A DNA element responsible for the different tissue specificities of Friend and Moloney retroviral enhancers. J. Virol. 1988;62:614–618. [PMC free article: PMC250577] [PubMed: 2826819]
  1258. Thomas C.Y., Coffin J.M. Genetic alterations of RNA leukemia viruses associated with the development of spontaneous thymic leukemia in AKR mice. J. Virol. 1982;43:416–426. [PMC free article: PMC256144] [PubMed: 6287025]
  1259. Thomas C.Y., Boykin B.J., Famulari N.G., Coppola M.A. Association of recombinant murine leukemia viruses of the class II genotype with spontaneous lymphomas in CWD mice. J. Virol. 1986;58:314–323. [PMC free article: PMC252915] [PubMed: 3009848]
  1260. Thomas C.Y., Coppola M.A., Holland C.A., Massey A.C. Oncogenicity and U3 region sequences of class II recombinant MuLVs of CWD mice. Virology. 1990;176:166–177. [PubMed: 2158688]
  1261. Thomas C.Y., Khiroya R., Schwartz R.S., Coffin J.M. Role of recombinant ecotropic and polytropic viruses in the development of spontaneous thymic lymphomas in HRS/J mice. J. Virol. 1984;50:397–407. [PMC free article: PMC255633] [PubMed: 6323740]
  1262. Thompson C.B., Humphries E.H., Carlson L.M., Chen C.L., Neiman P.E. The effect of alterations in myc gene expression on B cell development in the bursa of Fabricius. Cell. 1987;51:371–381. [PubMed: 3499231]
  1263. Tong L.A., deVos A.M., Milburn M.V., Jancarki J., Noguchi S., Nishimura S., Miura K., Ohtsuka E., Kim S.H. Structural differences between a ras oncogene protein and the normal proteins. Nature. 1989;337:90–93. [PubMed: 2642607]
  1264. Torres B.A., Griggs N.D., Johnson H.M. Bacterial and retroviral superantigens share a common binding region on class II MHC antigens. Nature. 1993;364:152–154. [PubMed: 8391645]
  1265. Torten M., Franchini M., Barlough J.E., George J.W., Mozes E., Lutz H., Pedersen N.C. Progressive immune dysfunction in cats experimentally infected with feline immunodeficiency virus. J. Virol. 1991;65:2225–2230. [PMC free article: PMC240570] [PubMed: 1673159]
  1266. Tracy S.E., Woda B.A., Robinson H.L. Induction of angiosarcoma by a c-erbB transducing virus. J. Virol. 1985;54:304–310. [PMC free article: PMC254798] [PubMed: 2985799]
  1267. Trahey M., McCormick F. A cytoplasmic protein stimulates normal N-Ras p21 GTPase but does not affect oncogenic mutants. Science. 1987;238:542–545. [PubMed: 2821624]
  1268. Treier M., Staszewski L.M., Bohmann D. Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain. Cell. 1994;78:787–798. [PubMed: 8087846]
  1269. Treisman R. Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences. Cell. 1985;42:889–902. [PubMed: 2414012]
  1270. Tremblay P.J., Kozak C.A., Jolicoeur P. Identification of a novel gene, Vin1, in murine leukemia virus-induced T-cell leukemias by provirus insertional mutagenesis. J. Virol. 1992;66:1344–1353. [PMC free article: PMC240856] [PubMed: 1738193]
  1271. Troxler D.H., Scolnick E.M. Rapid leukemia induced by cloned Friend strain of replicating murine type-C virus. Association with induction of xenotropic-related RNA sequences containing in spleen focus-forming virus. Virology. 1978;85:17–27. [PubMed: 206001]
  1272. Troxler D.H., Parks W.P., Vass W.C., Scolnick E.M. Isolation of a fibroblast nonproducer cell lines containing the Friend strain of the spleen focus-forming virus. Virology. 1977;76:606–615. [PubMed: 190768]
  1273. Troxler D.H., Yuan E., Linemeyer D., Ruscetti S., Scolnick E.M. Helper-independent mink cell focus-inducing strains of Friend murine type-C virus: Potential relationship to the origin of replication-defective spleen focus-forming virus. J. Exp. Med. 1978;148:639–653. [PMC free article: PMC2184996] [PubMed: 212504]
  1274. Trusko S.P., Hoffman E.K., George D.L. Transcriptional activation of cKi-ras proto-oncogene resulting from retroviral promoter insertion. Nucleic Acids Res. 1989;17:9259–9265. [PMC free article: PMC335129] [PubMed: 2555789]
  1275. Tsatsanis C., Fulton R., Nishigaki K., Tsujimoto H., Levy L., Terry A., Sapandidos D., Onions D., Neil J.C. Genetic determinants of feline leukemia virus-induced lymphoid tumors: Patterns of proviral insertion and gene rearrangement. J. Virol. 1994;68:8296–8303. [PMC free article: PMC237298] [PubMed: 7966623]
  1276. Tsichlis P.N., Bear S.E. Infection by mink cell focus-forming viruses confers interleukin 2 (IL-2) independence to an IL-2-dependent rat T-cell lymphoma line. Proc. Natl. Acad. Sci. 1991;88:4611–4615. [PMC free article: PMC51715] [PubMed: 2052545]
  1277. Tsichlis P.N., Lazo P.A. Virus-host interactions and the pathogenesis of murine and human oncogenic retroviruses. Curr. Top. Microbiol. Immunol. 1991;171:95–171. [PubMed: 1667631]
  1278. Tsichlis P.N., Shepherd B.M., Bear S.E. Activation of the Mlvi1/Mis1/Pvt1 locus in Moloney murine leukemia virus-induced T-cell lymphomas. Proc. Natl. Acad. Sci. 1989;86:5487–5491. [PMC free article: PMC297648] [PubMed: 2748599]
  1279. Tsichlis P.N., Strauss P.G., Hu L.F. A common region for proviral DNA integration in MoMuLV-induced rat thymic lymphomas. Nature. 1983;302:445–449. [PubMed: 6300684]
  1280. Tsichlis P.N., Strauss P.G., Kozak C.A. Cellular DNA region involved in induction of thymic lymphomas (Mlvi2) maps to mouse chromosome 15. Mol. Cell. Biol. 1984;4:997–1000. [PMC free article: PMC368860] [PubMed: 6328284]
  1281. Tsichlis P.N., Strauss P.G., Lohse M.A. Concerted DNA rearrangements in Moloney murine leukemia virus-induced thymomas: A potential synergistic relationship in oncogenesis. J. Virol. 1985a;56:258–267. [PMC free article: PMC252516] [PubMed: 2993654]
  1282. Tsichlis P.N., Lohse M.A., Szpirer C., Szpirer J., Levan G. Cellular DNA regions involved in the induction of rat thymic lymphomas (Mlvi1, Mlvi2, Mlvi3, and c-myc) represent independent loci as determined by their chromosomal map location in the rat. J. Virol. 1985b;56:938–942. [PMC free article: PMC252667] [PubMed: 2999446]
  1283. Tsichlis P.N., Lee J.S., Bear S.E., Lazo P.A., Patriotis C., Gustafson E., Shinton S., Jenkins N.A., Copeland N.G., Huebner K., Croce C., Levan G., Hanson C. Activation of multiple genes by provirus integration in the Mlvi4 locus in T-cell lymphomas induced by Moloney murine leukemia virus. J. Virol. 1990;64:2236–2244. [PMC free article: PMC249384] [PubMed: 1691313]
  1284. Tsubura A., Inaba M., Imai S., Murakami A., Oyaizu N., Yasumizu R., Ohnishi Y., Tanaka H., Morii S., Ikehara S. Intervention of T-cells in transportation of mouse mammary tumor virus (milk factor) to mammary gland cells in vivo. Cancer Res. 1988;48:6555–6559. [PubMed: 2846153]
  1285. Tsuchida M., Ohtsubo E., Ryder T. Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten murine sarcoma virus. Science. 1982;217:937–939. [PubMed: 6287573]
  1286. Tsuchie H., Chang C.H.W., Yoshida M., Vogt P. A newly isolated avian sarcoma virus, ASV-1, carries the crk oncogene. Oncogene. 1989;4:1281–1284. [PubMed: 2554234]
  1287. Tsuji Y., Doi H., Yamabe T., Ishimaru T., Niyamoto T., Hino S. Prevention of mother-to-child transmission of human T-lymphotropic virus type-I. Pediatrics. 1990;86:11–17. [PubMed: 2359666]
  1288. Tsujimoto H., Fulton R., Nishigaki K., Matsumoto Y., Hasegawa A., Tsujimoto A., Cevario S., J. O'Brien S., Terry A., Onions D. A common proviral integration region, Fit1, in T-cell tumors induced by myc-containing feline leukemia viruses. Virology. 1993;196:845–848. [PubMed: 8396812]
  1289. Tsukada S., Rawlings D.J., Witte O.N. Role of Bruton's tyrosine kinase in immunodeficiency. Curr. Opin. Immunol. 1994;6:623–630. [PubMed: 7946052]
  1290. Tucek C.L., Desaymard C., Papiernik M. A kinetic study on the deletion of thymic, peripheral and gut-associated Vβ6+ T cells in an MlsB BALB/c colony infected with an exogenous mouse mammary tumor virus (MMTV, SW). J. Immunol. 1993;151:759–766. [PubMed: 8101538]
  1291. Tupper J.C., Chen H., Hays E.F., Bristol G.C., Yoshimura F. Contributions to transcriptional activity and to viral leukemogenicity made by sequences within and downstream of the MCF13 murine leukemia virus enhancer. J. Virol. 1992;66:7080–7088. [PMC free article: PMC240380] [PubMed: 1331510]
  1292. Uemura Y., Kotani S., Yoshimoto S., Furishita M., Yamashita M., Ohtsuki Y., Taguchi H., Miyoshi I. Mother-to-offspring transmission of human T cell leukemia virus type I in rabbits. Blood. 1987;69:1255–1258. [PubMed: 2881588]
  1293. Ullrich A., Coussens L., Hayflick J.S., Downward J., Mayes E.L.V., Whittles N., Waterfield M.D., Seeburg P.H. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature. 1984;309:418–425. [PubMed: 6328312]
  1294. Ulrich E., Boehmelt G., Bird A., Beug H. Immortalization of conditionally transformed chicken cells: Loss of normal p53 expression is an early step that is independent of cell transformation. Cell. 1992;6:876–887. [PubMed: 1577279]
  1295. Usuku K., Sonoda S., Osame M., Yashiki S., Takahashi K., Matsumoto M., Sawada T., Tsuji K., Tara M., Igata A. HLA haplotype-linked high immune responsiveness against HTLV-I in HTLV-I-associated myelopathy: Comparison with adult T-cell leukemia/lymphoma. Ann. Neurol. 1988;23 (suppl.):S143–S150. [PubMed: 2894806]
  1296. Vallee H., Carre H. Nature infectieuse de l'anemiie du cheval. C.R. Acad. Sci. 1904;139:331–333.
  1297. Van Beveren C., Enami S., Curran T., Verma I.M. FBR murine osteosarcoma virus. II. Nucleotide sequence of the provirus reveals that the genome contains sequences from two cellular genes. Virology. 1984;135:229–243. [PubMed: 6203215]
  1298. Van Beveren C., van Straaten F., Curran T., Muller R., Verma I.M. Analysis of FBJ-MSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini. Cell. 1983;32:1241–1255. [PubMed: 6301687]
  1299. Van Den Broeke A., Cleuter Y., Chen G., Portetelle D., Mammerickx M., Zagury D., Fouchard M., Coulombel L., Kettmann R., Burny A. Even transcriptionally competent proviruses are silent in bovine leukemia virus-induced sheep tumor cells. Proc. Natl. Acad. Sci. 1988;85:9263–9267. [PMC free article: PMC282719] [PubMed: 2848258]
  1300. van der Geer P., Hunter T., Lindberg R.A. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol. 1994;10:251–337. [PubMed: 7888178]
  1301. van der Hoorn E.A., Hulsebos E., Berns A.J., Bloemers H.P. Molecularly cloned c-mos (rat) is biologically active. EMBO J. 1982;1:1313–1317. [PMC free article: PMC553210] [PubMed: 6327263]
  1302. van der Lugt N.M.T., Domen J., Verhoeven E., Linders K., van der Gulden H., Allen J., Berns A. Proviral tagging in Eu-myc transgenic mice lacking the Pim1 proto-oncogene leads to compensatory activation of Pim2. EMBO J. 1995;14:2536–2544. [PMC free article: PMC398367] [PubMed: 7781606]
  1303. Van Der Maaten M.J., Miller J.M. 1976Induction of lymphoid tumors in sheep with cell-free preparations of bovine leukemia virus In Comparative leukemia research 1975 (ed. J. Clemmsen and D.S. Yohn), pp. 377–379. Karger, Basel. [PubMed: 183702]
  1304. Van Etten R.A. The molecular pathogenesis of the Philadelphia-positive leukemias: Implications for diagnosis and therapy. Cancer Treat. Res. 1993;64:295–325. [PubMed: 8095796]
  1305. Van Etten R.A., Jackson P., Baltimore D. The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization. Cell. 1989;58:669–678. [PubMed: 2670246]
  1306. van Lohuizen M., Berns A. Tumorigenesis by slow-transforming retroviruses—An update. Biochim. Biophys. Acta. 1990;1032:213–235. [PubMed: 2261495]
  1307. van Lohuizen M., Breuer M., Berns A. N-myc is frequently activated by proviral insertion in MuLV-induced T cell lymphomas. EMBO J. 1989a;8:133–136. [PMC free article: PMC400781] [PubMed: 2653809]
  1308. van Lohuizen M., Verbeek S., Scheijen B., Wientjens E., van der Gulden H., Berns A. Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging. Cell. 1991;65:737–752. [PubMed: 1904008]
  1309. van Lohuizen M., Verbeek M., Krimpenfort P., Domen J., Saris C., Radaszkiewicz T., Berns A. Predisposition to lymphomagenesis in Pim1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors. Cell. 1989b;56:673–682. [PubMed: 2537153]
  1310. van Ooyen A., Nusse R. Structure and nucleotide sequence of the putative mammary oncogene int-1: Proviral insertions leave the protein-encoding domain intact. Cell. 1984;39:233–240. [PubMed: 6091914]
  1311. Varmus H.E., Quintrell N.E., Ortiz S. Retroviruses as mutagens: Insertion and excision of a nontransforming provirus alters expression of a resident transforming provirus. Cell. 1981;25:23–26. [PubMed: 6268304]
  1312. Velu T.J., Vass W.C., Lowy D.R., Tambourin P.E. Harvey sarcoma virus: Influences of coding and noncoding sequences on cell transformation in vitro and oncogenicity in vivo. J. Virol. 1989;63:1384–1392. [PMC free article: PMC247837] [PubMed: 2536840]
  1313. Vennstrom B., Raynoscheck C., Jansson L., Doederlein G., Lhotak V., Johnsson A., Beug H. Retroviral capture of c-erbB proto-oncogene sequences: rapid evolution of distinct viral genomes carrying mutant v-erbB genes with different transforming capacities. Oncogene. 1994;9:1307–1320. [PubMed: 8152791]
  1314. Vernant J.C., Maurs L., Gessain A. Endemic tropical spastic paraparesis associated with human T-lymphotropic virus type I: A clinical and seroepidemiological study of 25 cases. Ann. Neurol. 1987;2:123–130. [PubMed: 3030190]
  1315. Verwoerd D.W., Williamson A.L., DeVilliers E.M. Aetiology of jaagsiekte: Transmission by means of subcellular fractions and evidence for the involvement of a retrovirus. Onderstepoort J. Vet. Res. 1980;47:275–280. [PubMed: 6164973]
  1316. Verwoerd D.W., Payne A.L., York D.F., Myer M.S. Isolation and preliminary characterization of the jaagsiekte retrovirus (JSRV). Onderstepoort J. Vet. Res. 1983;50:309–316. [PubMed: 6676694]
  1317. Vijaya S., Steffen D.L., Robinson H.L. Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin. J. Virol. 1986;60:683–692. [PMC free article: PMC288942] [PubMed: 3490582]
  1318. Vijaya S., Steffen D.L., Kozak C., Robinson H.L. Dsi-1, a region with frequent proviral insertions in Moloney murine leukemia virus-induced rat thymomas. J. Virol. 1987;61:1164–1170. [PMC free article: PMC254077] [PubMed: 3029411]
  1319. Villemur R., Rassart E., DesGroseillers L., Jolicoeur P. Molecular cloning of viral DNA from leukemogenic Gross passage A murine leukemia virus and nucleotide sequence of its long terminal repeat. J. Virol. 1983;45:539–546. [PMC free article: PMC256447] [PubMed: 6300418]
  1320. Villemur R., Monczak Y., Rassart E., Kozak C., Jolicoeur P. Identification of a new common provirus integration site in Gross passage A murine leukemia virus-induced mouse thymoma DNA. Mol. Cell Biol. 1987;7:512–522. [PMC free article: PMC365095] [PubMed: 3031479]
  1321. Villeneuve L., Jiang X., Turmel C., Kozak C.A., Jolicoeur P. Long-range mapping of Mis2, a common provirus integration site identified in murine leukemia virus-induced thymomas and located 160 kilobase pairs downstream of Myb. J. Virol. 1993;67:5733–5739. [PMC free article: PMC237990] [PubMed: 8371338]
  1322. Villeneuve L., Rassart E., Jolicoeur P., Graham M., Adams J.M. Proviral integration site Mis-1 in rat thymomas corresponds to the Pvt1 translocation breakpoint in murine plasmacytomas. Mol. Cell Biol. 1986;6:1834–1837. [PMC free article: PMC367714] [PubMed: 3785181]
  1323. Viskochil D., Cawthon R., O'Connell P., Xu G., Stevens J., Culver M., Carey J., White R. The gene encoding the oligodendrocyte-myelin glycoprotein is embedded with the neurofibromatosis type 1 gene. Mol. Cell. Biol. 1991;11:906–912. [PMC free article: PMC359746] [PubMed: 1899288]
  1324. Viskochil D., Buchberg A.M., Xu G., Cawthon R.M., Stevens J., Wolff R.K., Culver M., Carey J.C., Copeland N.G., Jenkins N., White R., O'Connell P. Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus. Cell. 1990;62:187–192. [PubMed: 1694727]
  1325. Vogel U.S., Dixon R.A.F., Diel M.D., Marshall R.E., Scolnick E.M., Sigal I.S., Gibbs J.B. Cloning of bovine GAP and its interaction with oncogenic Ras. Nature. 1988;335:90–93. [PubMed: 2842690]
  1326. Vogelstein B., Kinzler K.W. The multistep nature of cancer. Trends Genet. 1993;9:138–141. [PubMed: 8516849]
  1327. Vogt M. Properties of “mink cell focus-inducing” (MCF) virus isolated from spontaneous lymphoma lines of BALB/c mice carrying Moloney leukemia virus as an endogenous virus. Virology. 1979;93:226–236. [PubMed: 219598]
  1328. Vojtek A.B., Hollenberg S.M., Cooper J.A. Mammalian Ras interacts directly with the seine/threonine kinase Raf. Cell. 1993;74:205–214. [PubMed: 8334704]
  1329. von Melchner H., Reddy S., Ruley H.E. Isolation of cellular promoters by using a retrovirus promoter trap. Proc. Natl. Acad. Sci. 1990;87:3733–3737. [PMC free article: PMC53977] [PubMed: 2339116]
  1330. von Weizsacker F., Beug H., Graf T. Temperature-sensitive mutants for MH2 avian leukemia virus that map in the v-mil and the v-myc oncogene respectively. EMBO J. 1986;5:1521–1527. [PMC free article: PMC1166975] [PubMed: 3017698]
  1331. Voronova A.F., Sefton B.M. Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion. Nature. 1986;319:682–685. [PubMed: 3081813]
  1332. Waanders G.A., Shakhov A.N., Held W., Karapetian O., Acha-Orbea H., MacDonald H.R. Peripheral T cell activation and deletion induced by transfer of lymphocyte subsets expressing endogenous or exogenous mouse mammary tumor virus. J. Exp. Med. 1993;177:1359–1366. [PMC free article: PMC2191020] [PubMed: 8386743]
  1333. Walker C., Canfield D.J., Love D.N. Analysis of leucocyte and lymphocyte subsets for different clinical stages of naturally acquired feline immunodeficiency virus infection. Vet. Immunol. Immunopathol. 1994;44:1–12. [PubMed: 7725628]
  1334. Walker W.H., Stein B., Ganchi P.A., Hoffman J.A., Kaufman P.A., Ballard D.W., Hannink M., Greene W.C. The v-rel oncogene: Insights into the mechanism of transcriptional activation, repression and transformation. J. Virol. 1992;66:5018–5029. [PMC free article: PMC241358] [PubMed: 1321284]
  1335. Wallbank A.M., Sperling F.G., Hubben K., Dubbs E.L. Isolation of a tumour virus from a chicken submitted to a poultry diagnostic laboratory-Esh sarcoma virus. Nature. 1966;209:1265. [PubMed: 4289160]
  1336. Waneck G.L., Rosenberg N. Abelson leukemia virus induced lymphoid and erythroid colonies in infected fetal cell cultures. Cell. 1981;26:79–89. [PubMed: 6276010]
  1337. Wang L.-H., Feldman R., Shibuya M., Hanafusa H., Notter M.F.P., Balduzzi P.C. Genetic structure, transforming sequences and gene product of avian sarcoma virus, UR1. J. Virol. 1981 [PMC free article: PMC256615] [PubMed: 6270378]
  1338. Wang X.M., Yew N., Peloguin J.G., Vande Woude G.F., Borisy G.G. Mos oncogene product associates with kinetochores in mammalian somatic cells and disrupts mitotic progression. Proc. Natl. Acad. Sci. 1994;91:8329–8333. [PMC free article: PMC44599] [PubMed: 8078882]
  1339. Wano Y., Feinberg M., Hosking J.B., Bogerd H., Greene W.C. Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth. Proc. Natl. Acad. Sci. 1988;85:9733–9737. [PMC free article: PMC282853] [PubMed: 3059351]
  1340. Warne P.H., Viciana P.R., Downward J. Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro. Nature. 1993;364:352–355. [PubMed: 8332195]
  1341. Watanabe T., Yamaguchi K., Takatsuki K., Osame M., Yoshida M. Constitutive expression of parathyroid hormone-related protein gene in human T cell leukemia virus type I (HTLV-I) carriers and adult T cell leukemia patients that can be trans-activated by HTLV-I tax gene. J. Exp. Med. 1993;172:759–765. [PMC free article: PMC2188541] [PubMed: 2388034]
  1342. Waterfield M.D., Scarce G.J., Whittle N., Stroobant P., Johnson A., Wasteson A., Westermark B., Heldin C.-H., Huang J.S., Deuel T.F. Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus. Nature. 1983;304:35–38. [PubMed: 6306471]
  1343. Weinberg R.A. The action of oncogenes in the cytoplasm and nucleus. Science. 1985;230:770–776. [PubMed: 2997917]
  1344. Weinberg R.A. The molecular basis of oncogenes and tumor suppressor genes. Ann. N.Y. Acad. Sci. 1995a;758:331–338. [PubMed: 7625701]
  1345. Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell. 1995b;81:323–330. [PubMed: 7736585]
  1346. Weinberger C., Thompson C.C., Ong E.S., Lebo R., Gruol D.J., Evans R.M. The c-erbA gene encodes a thyroid hormone receptor. Nature. 1986;324:641–646. [PubMed: 2879243]
  1347. Weinstein Y., Ihle J.N., Lavu S., Reddy E.P. Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line. Proc. Natl. Acad. Sci. 1986;83:5010–5014. [PMC free article: PMC323879] [PubMed: 3014527]
  1348. Weinstein Y., Cleveland J.L., Askew D.S., Rapp U.R., Ihle J.N. Insertion and truncation of c-myb by murine leukemia virus in a myeloid cell line derived from cultures of normal hepatopoietic cells. J. Virol. 1987;61:2339–2343. [PMC free article: PMC283705] [PubMed: 2884332]
  1349. Weiss R.A. 1993Cellular receptors and viral glycoproteins In The retroviridae (ed. J.A. Levy), vol. 3, pp.1–108. Plenum Press, New York.
  1350. Weiss R., Teich N., Varmus H., Coffin J. 1982 Molecular biology of tumor viruses, 2nd edition: RNA tumor viruses Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  1351. Weller S.K., Temin H.M. Cell killing by avian leukosis viruses. J. Virol. 1981;39:713–721. [PMC free article: PMC171305] [PubMed: 6270346]
  1352. Wellman M.L., Kociba G.J., Lewis M.G., Mathes L.E., Olson R.G. Inhibition of erythroid colony forming cells by a 15,000 dalton protein of feline leukemia virus. Cancer Res. 1984;44:1527–1529. [PubMed: 6322979]
  1353. Wendling F., Varlet P., Charon M., Tambourin P. MPLV: A retrovirus complex inducing an acute myeloproliferative leukemic disorder in adult mice. Virology. 1986;149:242–246. [PubMed: 3004028]
  1354. Westaway D., Payne G., Varmus H.E. Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors. Proc. Natl. Acad. Sci. 1984;81:843–847. [PMC free article: PMC344934] [PubMed: 6322173]
  1355. Westaway D., Papkoff J., Moscovici C., Varmus H.E. Identification of a provirally activated c-Ha-ras oncogene in an avian nephroblastoma via a novel procedure: cDNA cloning of a chimaeric viral-host transcript. EMBO J. 1986;5:301–309. [PMC free article: PMC1166733] [PubMed: 3011401]
  1356. Weston K., Bishop J.M. Transcriptional activation by the v-myb oncogene and its cellular progenitor. Cell. 1989;58:85–93. [PubMed: 2665942]
  1357. Whang-Peng J., Bunn P.A., Knutsen T., Kao-Shan C.S., Broder S., Jaffe E.S., Gelman E., Blattner W., Lofters W., Young R.C., Gallo R.C. Cytogenetic studies in human T-cell lymphoma virus (HTLV)-positive leukemia/lymphoma in the United States. J. Natl. Cancer Inst. 1985;74:357–369. [PubMed: 2983135]
  1358. Whetter L., Archambault D., Perry S., Gazit A., Coggins L., Yaniv A., Clabough D., Dahlberg J., Fuller J., Tronick S.R. Equine infectious anemia virus derived from a molecular clone persistently infects horses. J. Virol. 1990;64:5750–5756. [PMC free article: PMC248720] [PubMed: 2173767]
  1359. Whitlock C.A., Witte O.N. Abelson virus-infected cells can exhibit restricted in vitro growth and low oncogenic potential. J. Virol. 1981;40:577–584. [PMC free article: PMC256661] [PubMed: 6275106]
  1360. Whitlock C.A., Ziegler S.F., Witte O.N. Progression of the transformed pheontype in clonal lines of Abelson virus-infected lymphocytes. Mol. Cell. Biol. 1983;3:596–604. [PMC free article: PMC368575] [PubMed: 6304498]
  1361. Whyte P. The retinoblastoma protein and its relatives. Semin. Cancer Biol. 1995;6:83–90. [PubMed: 7647310]
  1362. Wilcox G.E., Chadwick B.J., Kertayadnya G. Recent advances in the understanding of Jembrana disease. Vet. Microbiol. 1995;46:249–255. [PubMed: 8545963]
  1363. Wilkerson M.J., Davis W.C., Cheevers W.P. Peripheral blood and synovial fluid mononuclear cell phenotypes in lentivirus induced arthritis. J. Rheumatol. 1995a;22:8–15. [PubMed: 7699688]
  1364. Wilkerson M.J., Davis W.C., Baszler T.V., Cheevers W.P. Immunopathology of chronic lentivirus-induced arthritis. Am. J. Pathol. 1995b;146:1433–1443. [PMC free article: PMC1870900] [PubMed: 7778682]
  1365. Williams N.G., Roberts T.M. Signal transduction pathways involving the Raf proto-oncogene. Cancer Metastasis Rev. 1994;13:105–116. [PubMed: 8143342]
  1366. Winslow G.M., Marrack P., Kappler J.W. Processing and major histocompatibility complex binding of the MTV7 superantigen. Immunity. 1994;1:23–33. [PubMed: 7889395]
  1367. Winslow G.M., Scherer M.T., Kappler J.W., Marrack P. Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a). Cell. 1992;71:719–730. [PubMed: 1330323]
  1368. Wirschubsky Z., Tsichlis P., Klein G., Sumegi J. Rearrangement of c-myc, Pim1 and Mlvi1 and trisomy of chromosome 15 in MCF- and Moloney-MuLV-induced murine T-cell leukemias. Int. J. Cancer. 1986;38:739–745. [PubMed: 3021636]
  1369. Withers-Ward E.S., Kitamura Y., Barnes J.P., Coffin J.M. Widespread distribution of targets for retrovirus DNA integration in vivo. Genes Dev. 1994;8:1473–1487. [PubMed: 7926746]
  1370. Witte O.N., Rosenberg N., Paskind M., Shields A., Baltimore D. Identification of an Abelson murine leukemia virus-encoded protein present in transformed fibroblasts and lymphoid cells. Proc. Natl. Acad. Sci. 1978;75:2488–2492. [PMC free article: PMC392579] [PubMed: 209468]
  1371. Witter R.L. 1984Reticuloendotheliosis In Diseases of poultry, 8th edition (ed. M.S. Hofstad), pp. 406–417. Iowa State University Press, Ames, Iowa.
  1372. Witter R.L., Johnson D.C. Epidemiology of reticuloendotheliosis virus in broiler breeder flocks. Avian Dis. 1985;29:1140–1154. [PubMed: 3008697]
  1373. Witter R.L., Salter D.W. Vertical transmission of reticuloendotheliosis virus in breeder turkeys. Avian Dis. 1989;33:226–235. [PubMed: 2546528]
  1374. Wolf D., Rotter V. Inactivation of p53 gene expression by an insertion of Moloney murine leukemia virus-like DNA sequences. Mol. Cell. Biol. 1984;4:1402–1410. [PMC free article: PMC368923] [PubMed: 6095069]
  1375. Wolff L., Ruscetti S. Malignant transformation of erythroid cells in vivo by introduction of a nonreplicating retrovirus vector. Science. 1985;228:1549–1552. [PubMed: 2990034]
  1376. Wolff L., Ruscetti S. The spleen focus-forming virus (SFFV) envelope gene, when introduced into mice in the absence of other SFFV genes, induces acute erythroleukemia. J. Virol. 1988;62:2158–2163. [PMC free article: PMC253318] [PubMed: 2835516]
  1377. Wolff L., Koller R., Davidson W. Acute myeloid leukemia induction by amphotropic murine retrovirus (4070A): Clonal integrations involve c-Myb in some but not all leukemias. J. Virol. 1991;65:3607–3616. [PMC free article: PMC241365] [PubMed: 1645785]
  1378. Wolff L., Scolnick E., Ruscetti S. Envelope gene of Friend spleen focus-forming virus: deletion and insertions in 3′ gp70/p15E-encoding regions have resulted in unique features in the primary structure of its protein product. Proc. Natl. Acad. Sci. 1983;80:4718–4722. [PMC free article: PMC384115] [PubMed: 6308646]
  1379. Wolff L., Tambourin P., Ruscetti S. Induction of the autonomous stage of transformation in erythroid cells infected with SFFV: Helper virus is not required. Virology. 1986;152:272–276. [PubMed: 3012873]
  1380. Wolff L., Kaminchik J., Hankins W.D., Ruscetti S.K. Sequence comparisons of the anemia and polycythemia-inducing strains of Friend spleen focus-forming virus. J. Virol. 1985;53:570–578. [PMC free article: PMC254672] [PubMed: 3968721]
  1381. Wolff L.G., Deinhardt F., Theilen G.H., Rabin H., Kawakami T., Bustad L.K. Induction of tumors in marmoset monkeys by simian sarcoma virus, type I (Lagothrix): A preliminary report. J. Natl. Cancer Inst. 1971;47:1115–1120. [PubMed: 5001258]
  1382. Wong P.K.Y. Moloney murine leukemia virus temperature-sensitive mutants: A model for retrovirus-induced neurological disorders. Curr. Top. Microbiol. Immunol. 1990;160:29–60. [PubMed: 2162285]
  1383. Wong P.Y.K., Soong M.M., MacLeod R., Gallick G.E., Yuen P.H. A group of temperature sensitive mutants of Moloney leukemia virus which is defective in cleavage of env precursor polypeptide in infected cells also induces hind limb paralysis in newborn CFW/D mice. Virology. 1983;125:513–518. [PubMed: 6836918]
  1384. Wong T.C., Hirano A., Lai M.M., Vogt P.K. Genome structure of the defective avian sarcoma virus PRCIV. Virology. 1982;117:156–164. [PubMed: 6278733]
  1385. Woodland D., Happ M.P., Gollob K.J., Pamer E. An endogenous retrovirus mediating deletion of αβ T cells? Nature. 1991a;349:529–530. [PubMed: 1846949]
  1386. Woodland D.L., Lund F.E., Happ M.P., Blackman M.A., Palmer E., Corley C.R. Endogenous superantigen expression is controlled by mouse mammary tumor proviral loci. J. Exp. Med. 1991b;174:1255–1258. [PMC free article: PMC2118998] [PubMed: 1658187]
  1387. Woolford J., McAuliffe A., Rohrschneider L.R. Activation of the feline c-fms proto-oncogene: Multiple alteractions are required to generate a fully transformed pheontype. Cell. 1988;55:965–977. [PubMed: 2849512]
  1388. Wyke J.A., Linial M. Temperature-sensitive avian sarcoma viruses: A physiological comparison of twenty mutants. Virology. 1973;53:152–161. [PubMed: 4350414]
  1389. Xu G.F., Lin B., Tanaka K., Dunn D., Wood D., Gesteland R., White R., Weiss R., Tamanoi F. The catalytic domain of the neurofibromatosis type 1 gene product stimualtes ras GTPas and complements ira mutants of S. cerevisiae. Cell. 1990a;63:835–841. [PubMed: 2121369]
  1390. Xu G., O'Connell P., Viskochil D., Cawthorn R., Robertson M., Culver M., Dunn D., Stevens J., Gesteland R., White R., Weiss R. The neurofibromatosis type 1 gene encodes a protein related to GAP. Cell. 1990b;62:599–608. [PubMed: 2116237]
  1391. Xu W., Harrison S.C., Eck M.J. Three-dimensional structure of the tyrosine kinase c-Src. Nature. 1997;385:595–602. [PubMed: 9024657]
  1392. Yamada Y. Phenotypic and functional analysis of leukemic cells from 16 patients with adult T-cell leukemia/lymphoma. Blood. 1983;61:192–199. [PubMed: 6600211]
  1393. Yamaguchi K., Nishimura H., Kohrogi H., Jono M., Miyamoto Y., Takatsuki K. A proposal for smoldering adult T-cell leukemia: A clinicopathologic study of five cases. Blood. 1983;62:758–739. [PubMed: 6224522]
  1394. Yamaguchi K., Yoshioka R., Kiyokawa T., Seiki M., Yoshida M., Takatsuki K. Lymphoma type adult T-cell leukemia—A clinicopathologic study of HTLV related T-cell type malignant lymphoma. Hematol. Oncol. 1986;4:59–65. [PubMed: 3009298]
  1395. Yamamoto J.K., Sprager E., Ho E.W., Okuda T., Theilen G.H. The pathogenesis of experimentally induced feline immunodeficiency virus (FIV) infection in cats. Am. J. Vet. Res. 1988;49:1246–1258. [PubMed: 2459996]
  1396. Yamamoto J.K., Hansen H., Ho E.W., Morishita T.Y., Okuda T., Sawa T.R., Nakamura R.M., Kau W.P., Pedersen N.C. Epidemiologic and clinical aspects of feline immunodeficiency virus infection in cats from the continental United States and Canada and possible mode of transmission. J. Am. Vet. Med. Assoc. 1989;194:213–220. [PubMed: 2537269]
  1397. Yamamoto N., Okada M., Koyangi Y., Kannagi Y., Kannagi M., Hinuma Y. Transformation of human leukoctyes by cocultivation with an adult T cell leukemia virus producer cell line. Science. 1982;217:737–739. [PubMed: 6980467]
  1398. Yamaoka S., Tobe T., Hatanaka M. Tax protein of human T-cell leukemia virus type I is required for maintenance of the transformed phenotype. Oncogene. 1992;7:433–437. [PubMed: 1549359]
  1399. Yang W.K., Kiggans J.O., Yang D.M., Ou C.Y., Tennant R.W., Brown A., Bassin R.H. Synthesis and circularization of N- and B-tropic retroviral DNA in Fv1 permissive and restrictive mouse cells. Proc Natl. Acad. Sci. 1980;84:7305–7309. [PMC free article: PMC349533] [PubMed: 6248878]
  1400. Yaniv A., Dahlberg J., Gazit A., Sherman L., Chiu I.M., Tronick S.R., Aaronson S.A. Molecular cloning and physical characterization of integrated equine infectious anemic virus: Molecular and immunologic evidence of its close relationship to ovine and caprine lentiviruses. Virology. 1986;154:1–8. [PubMed: 3750842]
  1401. Yao B., Zhang Y., Delikat S., Mathias S., Basu S., Kolesnick R. Phosphorylation of Raf by ceramide-activated kinase. Nature. 1995;378:307–310. [PubMed: 7477354]
  1402. Yarden Y., Escobedo J.A., Kuang W.-J., Yang-Feng T.L., Daniel T.O., Tremble P.M., Chen E.Y., Ando M.E., Harkins R.N., Francke Y., Friend V.A., Ullrich A., Williams L.T. Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature. 1986;323:226–232. [PubMed: 3020426]
  1403. Yazdanbakhsh K., Park C.G., Winslow G.M., Choi Y. Direct evidence for the role of COOH terminus of mouse mammary tumor virus superantigen in determining T cell receptor Vβ specificity. J. Exp. Med. 1993;178:737–741. [PMC free article: PMC2191119] [PubMed: 7688034]
  1404. Yetter R.A., Buller R.M.L., Lee J.S., Elkins K.L., Mosier D.E., Fredrickson T.N., Morse H.C. III. CD4+ T cells are required for development of a murine retrovirus-induced immunodeficiency syndrome (MAIDS). J. Exp. Med. 1988;168:623–635. [PMC free article: PMC2189016] [PubMed: 2842430]
  1405. Yew N., Mellini M.L., Vande Woude G.F. Meiotic initiation by the mos protein in Xenopus. Nature. 1992;355:649–652. [PubMed: 1531698]
  1406. Yew N., Strobel M., Vande Woude G.F. Mos and the cell cycle: The molecular basis of the transformed phenotype. Curr. Opin. Genet. Dev. 1993;3:19–25. [PubMed: 8384034]
  1407. Ymer S., Tucker W.Q., Sanderson C.J., Hapel A.J., Campbell H.D., Young I.G. Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene. Nature. 1985;317:255–258. [PubMed: 2413359]
  1408. York D.F., Vigne R., Verwoerd D.W., Querat G. Isolation, identification and partial cDNA cloning of genomic RNA of jaagsiekte retrovirus, the etiological agent of sheep pulmonary adenomatosis. J. Virol. 1991;65:5061–5067. [PMC free article: PMC248970] [PubMed: 1651422]
  1409. York D.F., Vigne R., Verwoerd D.W., Querat G. Nucleotide sequence of the jaagsiekte retrovirus, an exogenous and endogenous type D and B retrovirus of sheep and goats. J. Virol. 1992;66:4930–4939. [PMC free article: PMC241337] [PubMed: 1629959]
  1410. Yoshida M., Hattori S., Seiki M. Molecular biology of human T-cell leukemia virus associated with adult T-cell leukemia. Curr. Top. Microbiol. Immunol. 1985;115:157–175. [PubMed: 2579772]
  1411. Yoshida M., Miyoshi I., Hinuma Y. Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. Proc. Natl. Acad. Sci. 1982;79:2031–2035. [PMC free article: PMC346116] [PubMed: 6979048]
  1412. Yoshida M., Seiki M., Hattori S., Watanabe T. 1984aGenome structure of human T-cell leukemia virus and its involvement in the development of adult T-cell leukemia/lymphoma In Human T-cell leukemia/lymphoma virus (ed. R.C. Gallo et al.), pp. 141–148. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  1413. Yoshida M., Seiki M., Yamaguchi K., Takatsuki K. Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease. Proc. Natl. Acad. Sci. 1984b;81:2534–2537. [PMC free article: PMC345097] [PubMed: 6326131]
  1414. Yoshida M., Osame M., Misaomi K., Toita M., Kuwasaki N., Nishida Y., Niraki Y., Takahashi K., Nomura K., Sonoda S., Eirakum N., Ijichi S., Usuku K. Increased replication of HTLV-I in HTLV-I-associated myelopathy. Ann. Neurol. 1989;26:331–335. [PubMed: 2802532]
  1415. Young H.A., Gonda M.A., DeFeo D., Ellis R.W., Nagashima K., Scolnick E.M. Heteroduplex analysis of cloned rat endogenous replication-defective (30S) retrovirus and Harvey murine sarcoma virus. Virology. 1980;107:89–99. [PubMed: 6255681]
  1416. Youngren S.D., DeNoronha F. 1983A transmissible feline sarcoma virus containing sequences related to the K-ras on gene In RNA tumor viruses (ed. E. Scolnick and N. Hopkins), pp. 33–. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  1417. Yuen P.H., Szurek P.F. The reduced virulence of the thymotropic Moloney murine leukemia virus derivative MoMuLV-TB is mapped to 11 mutations within the U3 region of the long terminal repeat. J. Virol. 1989;63:471–480. [PMC free article: PMC247715] [PubMed: 2783465]
  1418. Zachary J.F., Knupp C.J., Wong P.K.Y. Noninflammatory spongiform polioencephalopathy caused by a neurotropic temperature-sensitive mutant of Moloney murine leukemia virus TB. Am. J. Clin. Pathol. 1986;124:457–468. [PMC free article: PMC1888357] [PubMed: 3766704]
  1419. Zeigel R.F., Clark H.F. Electron microscopic observations on a “C”-type virus in cell cultures derived from a tumor-bearing viper. J. Natl. Cancer Inst. 1969;43:1097–1102. [PubMed: 4982059]
  1420. Zeigel R.F., Clark H.F. Histologic and electron microscopic observations on a tumor bearing viper: Establishment of a “C”-type virus-producing cell line. J. Natl. Cancer Inst. 1971;46:309–321. [PubMed: 5165585]
  1421. Zenke M., Munoz A., Sap J., Vennstrom B., Beug H. V-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA. Cell. 1990;61:1035–1049. [PubMed: 1972036]
  1422. Zenke M., Kahn P., Disela C., Vennstrom B., Leutz A., Keegan K., Hayman M.J., Choi H.R., Yew N., Engel J.D., Beug H. v-erbA specifically suppresses transcription of the avian erythrocyte anion transported (band 3) gene. Cell. 1988;52:107–119. [PubMed: 2830979]
  1423. Zervos A.S., Gyuris J., Brent R. Mxi-1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell. 1993;72:223–232. [PubMed: 8425219]
  1424. Zhang X.-F., Settlemena J., Kyriakis J.M., Takeuchi-Suzuki E., Elldge E., Marshall M.S., Brudger J.T., Rapp U.R., Avruch J. Normal and oncogenic Ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Nature. 1993;364:308–313. [PubMed: 8332187]
  1425. Zhou R.P., Oskarsson M., Paules R.S., Schulz N., Cleveland D., Vande Woude G.F. Ability of c-mos product to associate with and phosphorylate tubulin. Science. 1991;251:671–675. [PubMed: 1825142]
  1426. Ziemiecki A., Hennig D., Gardner L., Ferdinand F.J., Friis R.R., Bauer H., Pedersen N.C., Johnson L., Theilen G.H. Biological and biochemical characterization of a new feline sarcoma virus: Theilen-Pedersen (TP1-FeSV). Virology. 1984;138:324–331. [PubMed: 6208683]
  1427. Zink M.C., Yager J.A., Myers J.D. Pathogenesis of caprine arthritis encephalitis virus. Cellular localization of viral transcripts in tissues of infected goats. Am. J. Pathol. 1990;136:843–854. [PMC free article: PMC1877653] [PubMed: 2327471]
  1428. Zsebo K.M., Williams D.A., Geissler E.N., Broudy V.C., Martin F.H., Atkins H.L., Hsu R.-Y., Birkett N.C., Okino K.H., Murdock D.C., Jacobsen F.W., Langley K.E., Smith K.A., Takeishi T., Cattanach B.M., Galli S.J., Suggs S.V. Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell. 1990;63:213–224. [PubMed: 1698556]