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Guidelines on Post-Exposure Prophylaxis for HIV and the Use of Co-Trimoxazole Prophylaxis for HIV-Related Infections Among Adults, Adolescents and Children: Recommendations for a Public Health Approach: December 2014 supplement to the 2013 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Geneva: World Health Organization; 2014 Dec.

  • This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

Cover of Guidelines on Post-Exposure Prophylaxis for HIV and the Use of Co-Trimoxazole Prophylaxis for HIV-Related Infections Among Adults, Adolescents and Children: Recommendations for a Public Health Approach

Guidelines on Post-Exposure Prophylaxis for HIV and the Use of Co-Trimoxazole Prophylaxis for HIV-Related Infections Among Adults, Adolescents and Children: Recommendations for a Public Health Approach: December 2014 supplement to the 2013 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection.

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REFERENCES

    SECTION 1. INTRODUCTION

    1.
    Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach. Geneva: World Health Organization; 2013. [18 November 2014]. http://www​.who.int/hiv​/pub/guidelines/arv2013/download/en. [PubMed: 24716260]
    2.
    Post-exposure prophylaxis to prevent HIV infection: joint WHO/ILO guidelines on post-exposure prophylaxis (PEP) to prevent HIV infection. Geneva: World Health Organization; 2007. [18 November 2014]. http://www​.who.int/hiv​/pub/guidelines/post-exposureprophylaxis/en.
    3.
    Guidelines on co-trimoxazole prophylaxis for HIV-related infections among children, adolescents and adults: recommendations for a public health approach. Geneva: World Health Organization; 2006. [18 November 2014]. http://www​.who.int/hiv/pub/plhiv/ctx/en. [PubMed: 26042326]

    SECTION 2. METHODS

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    Balshem H, Helfand M, Schünemann HJ, Oxman AD, Kunz R, Brozek J, et al. GRADE guidelines. 3. Rating the quality of evidence. J Clin Epidemiol. 2011;64:401–6. [PubMed: 21208779]
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    GRADE Working Group [website]. GRADE Working Group; 2014. [18 November 2014]. www​.gradeworkinggroup.org.
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    WHO handbook for guideline development. Geneva: World Health Organization; 2012. [18 November 2014]. http://apps​.who.int/iris​/bitstream/10665​/75146/1/9789241548441_eng.pdf.

    SECTION 3. GUIDING PRINCIPLES

    1.
    Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach. Geneva: World Health Organization; 2013. [18 November 2014]. http://www​.who.int/hiv​/pub/guidelines/arv2013/download/en. [PubMed: 24716260]

    SECTION 4. POST-EXPOSURE PROPHYLAXIS FOR HIV

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    Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach. Geneva: World Health Organization; 2006. [18 November 2014]. http://www​.who.int/hiv​/pub/guidelines/artadultguidelines.pdf.
    3.
    Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach. Geneva: World Health Organization; 2013. [18 November 2014]. http://www​.who.int/hiv​/pub/guidelines/arv2013/download/en. [PubMed: 24716260]
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    Ford N, Shubber Z, Irvine C, Vitoria M, Doherty M. Poster presentation TUPE154 [Internet]. Melbourne, Australia: 2014. [18 November 2014]. Adherence to post exposure prophylaxis: where do losses occur? http://www​.aids2014.org​/webcontent/file/pag​/Posters/Tuesday/Tuesday.pdf.
    11.
    Ford N, Irvine C, Doherty M, Vitoria M, Baggaley R, Shubber Z. Poster presentation TUPE154. Melbourne, Australia: 2014. [18 November 2014]. Variation in adherence to post exposure prophylaxis by exposure type: a meta-analysis. http://www​.aids2014.org​/webcontent/file/pag​/Posters/Tuesday/Tuesday.pdf.
    12.
    Otten RA, Smith DK, Adams DR, Pullium JK, Jackson E, Kim CN, et al. Efficacy of postexposure prophylaxis after intravaginal exposure of pig-tailed macaques to a human-derived retrovirus (human immunodeficiency virus type 2). J Virol. 2000;74:9771–5. [PMC free article: PMC112413] [PubMed: 11000253]
    13.
    Tsai CC, Emau P, Follis KE, Beck TW, Benveniste RE, Bischofberger N, et al. Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl) adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatment. J Virol. 1998;72:4265–73. [PMC free article: PMC109656] [PubMed: 9557716]
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    17.
    Benn P, Fisher M, Kulasegaram R., on behalf of the BASHH, PEPSE Guidelines Writing Group Clinical Effectiveness Group. UK guideline for the use of post-exposure prophylaxis for HIV following sexual exposure (2011). Int J STD AIDS. 2011;22:695–708. [PubMed: 22174049]
    18.
    Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, et al. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis. Infect Control Hosp Epidemiol Off J Soc Hosp Epidemiol Am. 2013;34:875–92. [PubMed: 23917901]
    19.
    Mayer KH, Mimiaga MJ, Cohen D, Grasso C, Bill R, VanDerwarker R, et al. Tenofovir DF plus lamivudine or emtricitabine for nonoccupational postexposure prophylaxis (NPEP) in a Boston Community Health Center. J Acquir Immune Defic Syndr. 2008;47:494–9. [PubMed: 18176318]
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    Schechter M, do Lago RF, Mendelsohn AB, Moreira RI, Moulton LH, Harrison LH, et al. Behavioral impact, acceptability, and HIV incidence among homosexual men with access to postexposure chemoprophylaxis for HIV. J Acquir Immune Defic Syndr. 2004;35:519–25. [PubMed: 15021317]
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    SECTION 5. THE USE OF CO-TRIMOXAZOLE PROPHYLAXIS FOR HIV-RELATED INFECTIONS AMONG ADULTS, ADOLESCENTS AND CHILDREN

    1.
    WHO expert consultation on co-trimoxazole prophylaxis in HIV infection. Geneva: World Health Organization; 2006. [18 November 2014]. http://www​.who.int/hiv​/pub/meetingreports​/ctxprophylaxismeeting.pdf.
    2.
    Guidelines on co-trimoxazole prophylaxis for HIV related infections among children, adolescents and adults: recommendations for a public health approach. Geneva: World Health Organization; 2006. [PubMed: 26042326]
    3.
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