Conserved Protein Domain Family
DUF4490

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pfam14892: DUF4490 
Domain of unknown function (DUF4490)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 101 and 220 amino acids in length. In mice, a member of this family whose expression is induced by p53 may play a role in DNA damage response.
Statistics
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PSSM-Id: 434291
Aligned: 20 rows
Threshold Bit Score: 109.352
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ELW48399       8 ECGEPAELKAKAtdPQEKTSDYYRVSADLPVR--FNHPGWFRGY-RTK-EAVSVYRTSNQAYGSRAPTVHEMPKVFYPNS 83 
XP_001372552   8 QSPQQDEEKAEV--YLEKTSDYYRVSKNLPTR--FNNPGWFRGY-RTK-ETHPLYRTTSQTYGSRAPTVHEMPKSFHSTE 81 
XP_003757510   8 QSSGHNEQKAEEg-YLEKTSDYYRVSQNLPAR--FNNPGWFRGY-RIK-ETHPVYRTSNQTYGSRAPTVHEMPKSFHTKS 82 
A0C7K1        64 TIGLELSQPISE--EEKQR---RKLDNKVPSKkfHVTEQEYKAPpQGInVGLPIYETSNMQYGQLNPTSFELIEKYYPRD 138 Paramecium tetr...
A0DF20        20 QFGLEQQK-------QKQRKRIRKIENKIPQKpfPVRKIKYKNTaQGInVGSPIYETSSMQYGQLNPTKFELIENFYPRD 92  Paramecium tetr...
XP_014346248  41 QNQTYGNTETEK--PLPKTSDFYRIDPTLPER--FNHPHCFQGYtRKK-QPHPLYTTSNQEYGKNAPTVHEMPTTFKGRS 115
B0UXH9        15 ETAGPGDSNTSE----IKTSDVYKVDKNLPSR--FNNPDCFR-Y-SHK-TTNPLYRTTNQAYGSKKPTVHEMPTSFNGSR 85  zebrafish
XP_006640702   2 enaTHTVEEANR--VSIKTSDVYKVQKNLPKR--FDNPDWFQGY-REK-PRNPLYRTTNQIYGGKRPTVHEMPTTFNGST 75 
EEN58978      26 EVDELGIPKGAK------TSEFYRVHEKLPAR--FDNPDWFQGY-RAK-GPHPQYRTSNGDYGGRNPNVHTMQTQFHGRS 95 
EGD81814      27 NEGNPVFSASGT----MKTSDLY-ATRNLPER--FDNPGEFKGYgKGKgGENPMYQTSSSSYGLLPPNVHTTPTAFHGLN 99 
ELW48399      84 NKFSRQLAACGMFQNNTFNICMEKS 108
XP_001372552  82 HSFSQHYGACGMYRSNGFNVFTDKS 106
XP_003757510  83 HTFSKHYEKCGMYRNNGFNVYTDKS 107
A0C7K1       139 ARFTQAFLG-DTFKFDGLNTSTAFS 162 Paramecium tetraurelia
A0DF20        93 AKFTQEFLG-HTYKFVGLITSVAFE 116 Paramecium tetraurelia
XP_014346248 116 QKFSDFYGKCGMYRDNGFNTCTERS 140
B0UXH9        86 HRFSEHLLKSGMYRDNGFNTMLDKS 110 zebrafish
XP_006640702  76 RQFTEYLSKCGMYKDNGFNTSTEKS 100
EEN58978      96 QKFSQHLGVCGMYRNHSFNTYVEKS 120
EGD81814     100 QKFSSHLGQAGMSRNTGLNTAKDKS 124
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