Conserved Protein Domain Family
BCOR

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pfam15808: BCOR 
BCL-6 co-repressor, non-ankyrin-repeat region
BCOR is a domain family found in eukaryotes, and is approximately 220 amino acids in length. This domain lies just upstream of the ankyrin-repeat region at the C-terminus of BCL-6 co-repressor proteins. The function of this region is not known.
Statistics
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PSSM-Id: 434953
Aligned: 10 rows
Threshold Bit Score: 141.207
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_015219729 1269 GLRLRKQRPLQELRQLWEQQVspq----------rsVLAAappPPPPPPHGRKDPAEPCPPE-------VTArdrKVKgS 1331
XP_003430713 1202 GLHPKKQRHLQHLRELWEQQV---------------APAErppPSKLGRQSRKDLAEAVQPE-------VTA---KVK-D 1255
XP_023374901 1155 GLHPKKQRHLLHLRERWEQQV---------------SAAD----SKPGRQSRKEVTQAVQPE-------ATT---QGN-N 1204
XP_017205322 1206 GLHPKKQRHLLHLRERWEQQV---------------SAAE----NKGARQSRKEVTQALPSE-------VTI---QGN-D 1255
ELK15822     1129 GLHPKKQRHL-HRREQSKQQR---------------SATE----NKPSWKGRKEMTQAVWPE-------VTS---RDN-N 1177
XP_001366913 1162 GLHPKKQRHLQHLRELWEQQV---------------SPPErspPSKLGRQSRKDLAEAVQPE-------VTA---KVK-D 1215
XP_005995319 1199 GLHPKKQRHLQHLRELWEQQ----------------VLPEratSCKPIRHSRKDLAEDWQPE-------VTTkerKVK-D 1254
Q6W2J8       1195 GLRLSKPRHLHNLQELWDRQGqlnhdrpqfgatnlgLPPTskaSIPPLQTTRREKLDPCTPEvprvahgVPAvdrKVKtN 1274 zebrafish
XP_029689389 1229 GLRLSKPA-----------------------------------AGAASPEGSLNKQERAWSQfnvvapgQSLrdhKIRpC 1273
1_pfamImport    1 GLRLSKPHLAAELRQWWTSQ-----------------------PSGEGQSSAGRGQTGHLPR---------GtsqKVN-- 46  
XP_015219729 1332 LVEEKPT--KKRSEGKVNRSW------SEEPLCKSDIEQGLPVPPVt--SPHADCLDSPPPDAAVSRKPPLAAATRLSDK 1401
XP_003430713 1256 CTEEKPT--RKRSEVKSNRSW------SEEPLKTSDHEQGLPAFPL---PPLTKTLPPASAGGKRQSQPGPTPASRPPAK 1324
XP_023374901 1205 ITEEKPG--RKRAEAKTNRSW------SEESLKSSDNEQGLPVFSG---SPPMKSLSSTNVSGKKQTQPSCTPASRPSAK 1273
XP_017205322 1256 ISEEKAS--RKRTEAKGNRSW------SEESLKSSDNEQGLPAFSS---SLPRTSLSSTNASGKKQTQPSCTPASRLPAR 1324
ELK15822     1178 ISKDRQGqdRTRAEAKGNRSW------LEDSLTSGENEQGFSVFSS---SLSMKTLSSASARSKEGAQPNYISAFSLHTE 1248
XP_001366913 1216 CTEEKHP--RKRSEVKSNRSW------SEESLRTSDNVQGLPVFPV---SPHMKSLSSTNANGKRQTQPSCTPASRLAAK 1284
XP_005995319 1255 WAEEKHT--RKRSEVKSSRSW------SEESLGRSDIGQGLLTPLS---SPHQKNLSASTENVKKQTESNSTPASKAAAK 1323
Q6W2J8       1275 GIEEKGL--KRKA--EVERGW------TKEQLEYAESNTAIPALSDsfcSDSIRKFSSAV------------PPHHLSDK 1332 zebrafish
XP_029689389 1274 EADDRAA--VQKS--DINRKW------GCEKLLN-----GVSALPP---GQLKDRLQP----------P------GPFSG 1319
1_pfamImport   47 -ARSKPLrkQNRTRECAKRKWgknwekGQSEFQEEEFSPGFLMAPPs--SPAHLQGSS--APQQAFASP---PSSCCQDK 118 
XP_015219729 1402 RQRLKEHRKAsg--------lGPPSPGSGKDAETTPWL--RRHSD-LEKPKGKRQCKTKHISLRDRRRASQTAEESA--- 1467
XP_003430713 1325 QQKIRESRKT-----------DVPCTDEEDDFQPASLL--QKFGD-CEKPAGKRQCKTKHLMLQERRRRTSLTGDDS--- 1387
XP_023374901 1274 QQKIKESQKT-----------DVLCTDEEEDCQAASLL--QKYTDnSEKPSGKRLCKTKHLIPQEPRRGLSMTGD----- 1335
XP_017205322 1325 QPRLKESPKP-----------DVLCTDEDEGCPAASLL--QKYPDhSEKPSGKRLCKTKHLISQEPRRGLALPGD----- 1386
ELK15822     1249 HQKIKESQNT-----------DILCTNDKYDSQAASPL--QQYTDnSEKPSGKRLRKTKHLIPQEPRQGLLMRN------ 1309
XP_001366913 1285 QQKIKESRKT-----------DVLCTDEEEDFQPASLL--QKYTD-CEKPSGKRQCKTKHLTPQERRRRSSLTGDDT--- 1347
XP_005995319 1324 RQKTKERRAT-----------DTTCTDEEEDFATTLTL--PKCTE-HEKPPGKRQCKTKHLTRQERRRS-SLTGDDA--- 1385
Q6W2J8       1333 RQRLKEHRKSv----------GSSSPSPDPDCTFPGRL--RRHGD-PEKPKGKRQCKTKHLSQQERRMLLQSTNQEC--- 1396 zebrafish
XP_029689389 1320 DRGLKEPRRD-----------PPSSPASQLSMGGAPPLksRRHSD-TDKPKGKRPCKTKHTSLKDREKKKEGTLNSPgqh 1387
1_pfamImport  119 HQKLREPQGLcgflssvpslpPPSSPSPDS----------HPHEDdLTKPKGKRPCKTKHTELQGKARILSVDAWRRaas 188 
XP_015219729 1468 --DLESPVEQKVSLKRST--RKR--------SASVSDYESSPVK 1499
XP_003430713 1388 --PEAENPEDKVTVTRRF--RKR--------PEPASDCDSSPAK 1419
XP_023374901 1336 --YYVENADGKMTV-RRF--RKR--------PESSSDYDLSPAK 1366
XP_017205322 1387 --YYVDNADGKMTV-RRV--RKR--------PEPSPDYDASPPA 1417
ELK15822     1310 --YCIKNADGKVTM-QRL--RKQ--------PEPSFDCDLSPVK 1340
XP_001366913 1348 --TDIENNEDKVMVTRRF--RKR--------PEPASECDSLPSK 1379
XP_005995319 1386 --TDIESSEEKVTTARRF--RRL--------LVPILDSDSSPTK 1417
Q6W2J8       1397 --PELSPAHQHKVVKCSA--QKR--------PALLSNYESSPIK 1428 zebrafish
XP_029689389 1388 ciVELGPADGDKPIEQRGaqRKR--------DASPNHYPCSPVK 1423
1_pfamImport  189 ------------------fdRRRtfyvsvvaPPSSKSRNVKPPR 214 
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