Conserved Protein Domain Family
DUF3719

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pfam12516: DUF3719 
Protein of unknown function (DUF3719)
This domain family is found in eukaryotes, and is approximately 70 amino acids in length. There is a conserved HLR sequence motif. There are two completely conserved residues (W and H) that may be functionally important.
Statistics
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PSSM-Id: 463617
Aligned: 22 rows
Threshold Bit Score: 70.8317
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_005474333 123 DLYEGRGSGGgiLQGLQDECQQWATRFPHLRILGTQLLCPSDEGFQWYT-TS-GKGSASSRPSAGKESGV 190
XP_005005388   8 LLYERKLSVH--TRSLHDECQQWTSSFPHLRILGRQIITPS-EGYELYPrSP-SAVSVSQEAVLSQERDS 73 
XP_012656876 113 LLYEQKLSMH--TKILQEECQQWTASFPHLRILGRQIIAPS-EDDGFYPrSP-T-VSASYEAPLSQERDS 177
XP_002718468 114 LLYERKLSVH--TKSLQEECQEWTASFPHLRILGRQIITPS-EDYGLYPrCP-SVLSASREATLPQERDS 179
XP_012396086 114 LLYEQKSSIH--TKGLQEECQQWTSTFPHLRILGKQIVTSC-EGYGLYPrSP-SVISASHETTLNQEKES 179
Q6NSV7       116 LLYEQQLSAH--TQGLQKECQQWAASFPHLRILGRQIITPS-EGYGLYPrSP-SAVSASHEATLSQERES 181 house mouse
A1L253       125 LLYERKCETQ--LKGLQDECQEWAFRFPHLRILGTQVVCPTDEGFQWYA-TP-AQTPSPSSSFQSKENTV 190 zebrafish
XP_011482661 121 ELYEGRGSGSgiLPGLKEECQQWTMRFPHLRILGKQLLPPTDEGFQWYA-TP-EGVTPADSPSTGKENSV 188
XP_002603051 119 MLYEGRQKGN---QQIYNECKEWVSMFPHLRICGAQLLEPQDQGFRHIP-----SEGTARPSTGTVVTDM 180
EDO26966      29 MLFEGKGFNG--SSQLLLECQEWCTKFPHLRICGVQSVHPQDEGTQYVPlPPdDPRVYNYRPQTSVLEDM 96 
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