Conserved Protein Domain Family
DLC-like_DYNLT3

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cd21463: DLC-like_DYNLT3 
dynein light chain (DLC)-like domain found in dynein light chain Tctex-type 3 (DYNLT3) and similar proteins
Dynein light chain Tctex-type 3 (DYNLT3), also called rp3, or protein 91/23, or T-complex-associated testis-expressed 1-like, is a non-catalytic accessory component of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. It has a potential role in chromosome congression in human mitosis and is required for chromosome alignment during mouse oocyte meiotic maturation. The DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3. The model corresponds to the dynein light chain (DLC)-like domain of DYNLT3.
Statistics
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PSSM-Id: 412011
Aligned: 6 rows
Threshold Bit Score: 179.319
Created: 3-Feb-2020
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P51808        16 EEAHNIVKECVDGVLggedyn-hnninQWTASIVEQSLTHLVKLgkaYKYIVTCAVVQksayGFHTASSCFWdtTSDGTC 94  human
XP_005999557  15 EEASDMVKECIEGVIgrvdyn-hnqvnQWTAGIVEQSLTQLVKLgkpLKYIVNCAVMQksgaGLHTANSCFWdtTTDGSC 93  coelacanth
NP_991171     15 DDASNVVKECIEGIIggvdys-qnkvnQWTASIVEHSLTQLVKQgkpFKYIVNCAVMQksgaGLHTANSCYWdtTTDGSC 93  zebrafish
XP_007899582  17 DETSNVVKECIENIIgggidynhskinQWTATIVEQSLMHLVKMgkpFKYIVTCAVMQksgaGLHTASSCYWdsSTDGSC 96  elephant shark
NP_001088001  14 DEASIVVKECVDVILggvdyd-enrinEWMSAVVEQSLTHLVKMgkaFKYIVSCTVMQkrgsGLHAASSCFWdnNTDGSC 92  African clawed ...
NP_001264663  16 DEAHNIVKECIESVLgkadyn-hnkvnQWTAAIVEQSLTHLVKLgktYKYIVTCAVMQrsgaGLHTASSCFWdtTTDGTC 94  chicken
P51808        95 TVRWENrtmNCIVNVFAI 112 human
XP_005999557  94 TVRWENrtmYCIVSVFAV 111 coelacanth
NP_991171     94 TVRWENrtmYCVVSVFAV 111 zebrafish
XP_007899582  97 TVRWENksmYCVVSVFAV 114 elephant shark
NP_001088001  93 TVRWENrtmYCVVSVFAV 110 African clawed frog
NP_001264663  95 TVRWENrtmNCIVNVFAV 112 chicken
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