Conserved Protein Domain Family
UQCC3

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pfam15141: UQCC3 
Ubiquinol-cytochrome-c reductase complex assembly factor 3
Complex III (cytochrome bc1) is a protein complex of the mitochondrial inner membrane that transfers electrons from ubiquinol to cytochrome c. UQCC3 functions in complex III assembly. The human UQCC3 is the ortholog of the fungal complex III assembly factor CBP4. It is also a potent antiviral protein independent of interferon production.
Statistics
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PSSM-Id: 464526
Aligned: 20 rows
Threshold Bit Score: 85.1415
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_004874445   1 MGALRKVLVTVAAMGAGAVVGSALFALVTPGELQKQALLKEIP---EQHRQHRDEKAHTQRLVMSTLQEATATQENVAWR 77 
XP_003774105   1 MGSLFKALQVAAVLGAGGGLGVFLFVLVTPGEQRTRELLKEIP---EGNPQRWDEATKTKMLLLDTLREATETHENVAWR 77 
Q6UW78         1 MDSLRKMLISVAMLGAGAGVGYALLVIVTPGERRKQEMLKEMP---LQDPRSREEAARTQQLLLATLQEAATTQENVAWR 77  human
XP_003419520   1 MAAVRKVLTMGVVLGLGVGFGSALFVLVTPGEQRTQEMLKEMP---GQDAQRRAEAVKSKELLLATLQEAAATQENVTRR 77 
B3DFP2         1 MSGMR-ILTGSVALG---GLTYAIWIIFSPGEERKKEILKSLP---EANPVRMEETRKRNAIMLQVLKDAAETNDNIAR- 72  zebrafish
XP_002051828   1 MASNPYVKSVLWLVGFG-GIGYGLMLLTEPSAEKIERI---KA---SGSPGQYNADDKKKALFMQKLQEAATSSTPIYRQ 73 
EDW28887       1 MFGNPYLKSILWLVSFG-GIGYGLMLLTEPNAEKIERI--KAS---ARGHPNQTDDEKKKALFMKRLQEAANTSAPIYRT 74 
XP_001988989   1 MASNPYVKSVLLLVGAG-GLGYALMLLTEPNAEKIERI--KAS---ARGPRQFNADDEKKALFMKKLQEAAINSTPIYRQ 74 
XP_002001655   1 MASNPYVKSIVLLLGSG-GIGYGLMLLTEPSAEKLERI---------KASGSLNADQQKKALFLQKLKEAATDSTPIYRQ 70 
XP_003342168  22 MESLRKSLQAVAVLGAGAGLGVFLFVLVTPGEQRTRDL---LKdiqEKNPQHLDEATKSKILWMDTLREAAETQENVAWR 98  gray short-tail...
XP_004874445  78 KNW-----MGGGGR 86 
XP_003774105  78 KDWn----RREGGR 87 
Q6UW78        78 KNWmvggeGGAGGR 91  human
XP_003419520  78 KNWmh--gSGSSGR 89 
B3DFP2        73 --------GFGSQK 78  zebrafish
XP_002051828  74 A-------ANTDKK 80 
EDW28887      75 --------PTGDKR 80 
XP_001988989  75 TP------TAADKK 82 
XP_002001655  71 R-------PGADKK 77 
XP_003342168  99 KDWn----RQAGGR 108 gray short-tailed opossum
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