3G9W,6T36,7BYJ,4DXA


Conserved Protein Domain Family
FERM_M

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pfam00373: FERM_M 
FERM central domain
This domain is the central structural domain of the FERM domain.
Statistics
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PSSM-Id: 459788
Aligned: 58 rows
Threshold Bit Score: 68.0647
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3G9W_A     18 DQNVDSrDPVQLNLLYVQARDDILNGSH-PVSF--EKACEFGGFQAQIQFGP---------------------------- 66  
Q80X40    291 ETPLHFdHSTYTETHYGQVLRDYLQGKLiVSTQaeALLAQLAAFQHFDKTGT---------------------------- 342  house mouse
P28191    114 RDPNRLrDEFTRFQFYQQVRQNLEEGRL-PCNE--GSLALLASYVVQAEVGD---------------------------- 162  Caenorhabditis el...
Q4SAH4     66 PDPVALkEEITRYLVFLQVKRDLYHGRL-LCKT--SDAALLAAYILQAEIGD---------------------------- 114  spotted green puf...
Q5BZ06    120 DPVHDLaQSLSRYLMYLQIRRDLTQGRL-LCPA--SIVGKLGALVAQAEIGD---------------------------- 168  Schistosoma japon...
Q7Q844     95 ADPLRLtNN-GKLMLYQQLKRDLRHGRL-YCSA--GEAAALGALIVQDELGD---------------------------- 142  Anopheles gambiae...
Q962Y3     55 PDPSQLqEDITRYQLCLQIRDDILKGRL-PCSF--VTHALLGSYIVQSELGD---------------------------- 103  Belcher's lancelet
Q6TEM9     82 VEPHLIlQEQTRHLFFMHVKEDLHRGHLrMCS---EQAQELSALLAQAEFGD---------------------------- 130  zebrafish
Q8SWW8     90 VPVHFIlQESVRNLFYMQARRDLLEGRLtAPDW--SGAAKLAALLCQAD--Glrfnesslkadcpmrmrrelaqqqqqqq 165  fruit fly
KJE94716 1788 TNEEWKrGGFLAEIMYYQVLDRYLKGHH-KVDV--DQVAKLAALQYRVENHDmqafmsnvcsvcnnpaskrc-------- 1856
3G9W_A        --------------------------------------------------------------------------------     
Q80X40        --------------------------------------------------------------------------------      house mouse
P28191        --------------------------------------------------------------------------------      Caenorhabditis el...
Q4SAH4        --------------------------------------------------------------------------------      spotted green puf...
Q5BZ06        --------------------------------------------------------------------------------      Schistosoma japon...
Q7Q844        --------------------------------------------------------------------------------      Anopheles gambiae...
Q962Y3        --------------------------------------------------------------------------------      Belcher's lancelet
Q6TEM9        --------------------------------------------------------------------------------      zebrafish
Q8SWW8    166 qqaqqhrleqqrkekehvlsfkkrrlskqksmehievctlpaasttscslqpspsasasasasasasasastsacsqths 245  fruit fly
KJE94716 1857 ---------------------------------------------------------------sgcklasycsrecqqkd 1873
3G9W_A     67 ---HVEHKHKPG-----FLDLKEFLPKEy--------------------------------------------------- 87  
Q80X40    343 -------SSPPS-----EQELLSYIPKPl--------------------------------------------------- 359  house mouse
P28191    163 ---FEEKTHGMSrtclcYKIQFATLPDDf--------------------------------------------------- 188  Caenorhabditis el...
Q4SAH4    115 ---YDPGKHPEG-----YCSKFQFFPKH---------------------------------------------------- 134  spotted green puf...
Q5BZ06    169 ------------------------APTEnvevstgdvvccappslydtrlnsvestefanmsttnncdqsiqeetldyaa 224  Schistosoma japon...
Q7Q844    143 ---YDAEAHTGE-----YVSSLKIALRQ---------------------------------------------------- 162  Anopheles gambiae...
Q962Y3    104 ---YDPEEHSAD-----YLSEFKFAPNQ---------------------------------------------------- 123  Belcher's lancelet
Q6TEM9    131 ---YNQNTAKYW-----YTELCGSEPNQt--------------------------------------------------- 151  zebrafish
Q8SWW8    246 nssSSSPSNSSS-----QTGLDERLASNplrvyee--------------------------------------------- 275  fruit fly
KJE94716 1874 wnvHQHVCGHEKlqagiQWRWGKYIPREl--------------------------------------------------- 1902
3G9W_A     88 ---------IKQRGA---EKRIFQEHKNCG-EMSEIEAKVKYVKLARSLRTYGVSFF 131 
Q80X40    360 ---------QWQVNTaniKSLVTQELRQMQ-GYSKQRAQIGFIESTAQLPLFGYTVY 406  house mouse
P28191    189 ------------------SDRVAELHQLHI-GQTPDVAEQNFLDHARRLEMYGMDVY 226  Caenorhabditis elegans
Q4SAH4    135 --------------SeklERRIAEIHKTELiGQCPETSELNFLQKAQMLETYGVDPH 177  spotted green pufferfish
Q5BZ06    225 ccnmlrklkIIFNQTpevEAQIMEEYQKLR-GLKAVEAETELLQRASQLPTYGIDPV 280  Schistosoma japonicum
Q7Q844    163 --------------SdqlEKKAMELHQKRDpGQEAVAVYDEFVGIARSLETYGIDPH 205  Anopheles gambiae str. PEST
Q962Y3    124 --------------TkelEEKVMELHKTHK-GQTPAEAELHYLENAKKLAMYGVDLH 165  Belcher's lancelet
Q6TEM9    152 -----------------tINSIIAKHKALE-GLSQASVEYQALQLVSSLEHYGVEWH 190  zebrafish
Q8SWW8    276 --yfmqpscEGEPPAdylRQIAVEHGKLAKlQMSLKTAKYWLLKSIQDLEGYGEELF 330  fruit fly
KJE94716 1903 ---------RTFMRQdewETRVFAQNKYIK-DMDHEAAMQHFLTEVMAWPHIATNVY 1949
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