Conserved Protein Domain Family
GCR

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pfam02155: GCR 
Glucocorticoid receptor
Statistics
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PSSM-Id: 426625
Aligned: 7 rows
Threshold Bit Score: 469.357
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5R9P5        26 VMDFYKTLRGGA---TVKVSASSPSLAVASQSDSKQRR-----LLVDFPKGSVSNA-QQPDLSKAVSLSMGLYMGETETK 96  Sumatran orangutan
XP_001368983  27 VMDFYKTIRGGA---AVKIPVSSPSLAAASQSDSKQQQqqqqpILGDFSKGTAGSA-QQPDLSKAVSLSMGLYMGDTDSK 102
XP_001510749  29 VMNFYTTLRGGA---IVKVSASSSPLAAASQSETKQQL-----VLGDFSKGSVSNApPQPDLSKAVSLSMGLYMGETETK 100
XP_003217421  28 VLDFNPSLRSGT---TIKIPASASPLPVSSEPDSIQQP-----VLCDLSKGLGCNV-PQPDLSKAVSLSMGLYMGETDTK 98 
XP_015149519  28 VMDFHPPFRGGA---SAQAPVSAAPLPVSSQSDSAQQP-----ALADFSKGLVNNV-PPPDLSKAVSLSMGLYMGETDAK 98 
XP_014343931  27 VYDFNPVFRGGA---PIPLTPAS-SLLLVSEADSPRQL-----ASGDTSNGVSGNA-TPQDLSQAVSESMGLYMGESDSK 96 
Q501U9        18 TLDYNKRATEGIlprRIQSTMSVAPTSMVPQAGPMMQP-----VSGDIPNGLSNSP-TLEEHTSSVS-S--IFGDDSELK 88  zebrafish
Q5R9P5        97 VMGND-LGFPQQGQISLSSGETDLKLLEESIANLNRSTSVPENPKSSASTAvsaapTEKEF-P-KTHSDISSEQQ-HLKG 172 Sumatran orangutan
XP_001368983 103 VMGND-LVFPQQGQIGVSSGETDFRLLEESIASLNKSARVPQSPKSSTSSA-----TDNEF-PtKSNCDKALEKPtFKKG 175
XP_001510749 101 VMGND-LGFPQQGQIGVSSGETDFRLLEESIASLNKSSGVPESSKGPAPAG-----PDKEF-PtTTDCDLALEQRtSVQG 173
XP_003217421  99 VMGNE-LGFPQKGQISLSSGDTDFRLLEESIASLNKSSSLAEGSKGATSIDt---sLESEF-PsMAGRDLTLDQGaLAQG 173
XP_015149519  99 VMGND-LGFSQQGQTGISSGETDFRLLEESIASLNKSSSLAEDAKGAVSSEa---pLEPDF-VgMAGRG-PLEPGaSVQS 172
XP_014343931  97 VIGQK-ARLQKQGQISGLSVETEFALLEESIASLNRSTRI-----GEVSGSlapgqVSLDNgSgMAKCDLSVEQEtFAQT 170
Q501U9        89 LLGKEqRALQQQTLVPFT-LGDSLSGLEASIADLNNPSPSMDSLIGGVDPNlfplkTE-DF-SpMIKGDMDLDQDsFGHI 165 zebrafish
Q5R9P5       173 QTGTNGGNVKLYTTDQSTFDILQDLEFSSGSPGKETNESPWRSDLLIDEN--CLLSPLAGeDDSFLLEGNSNEDCKPLIL 250 Sumatran orangutan
XP_001368983 176 SAGTKDGNAKLYTEDQSTFDILQDLELSAGSPGKETNESPWRLDPLLDEN--CLLSPLAT-DDPFLLEGNADEDCKPLIL 252
XP_001510749 174 QTGATGGNVKLYTEDQSTFDILQDLELPTRSPGREANDSPWRLDPLLEEG--GLLSPLGA-DDPFLLEGSASEDCKPLLL 250
XP_003217421 174 QVGTNGGNLKLFSEDQSTFDILQDFDLPPVSPGKETNGSPWRIDPVLDES--SLLSPLGG-DEGYLLEGNEMEDCKPPIL 250
XP_015149519 173 QVGSNGGSLKLFSEDQSTLDILQDLELPSVSPGKEPNGSPWRLDPLLDDG--GLLSPISA-DDTFLLEGNLGEDCKPPIL 249
XP_014343931 171 DSDPNGN-LSFFPDDQAAFDILQELDLTPCSPGKE---NPWSLDPIYDGGgrGLLSPLAA-DDPFLMAAVANEDCKSSLV 245
Q501U9       166 GKDVDVGNHKLFSDN--TLDLLQDFELDG-SP----------SDFYVADD--AFLSTIG--EDALLSELPTNLDRDSKAA 228 zebrafish
Q5R9P5       251 PDTKPKIKDNGDLVLSSpSNVTLPQVKTEKEDFIELCTPGVIKQEKLGTVYCQAGFPGANIIGNKMSAISVHGVSTSGGQ 330 Sumatran orangutan
XP_001368983 253 PDTKPKITEQGGLILPS-SNMPLPQVKTEKEDFIELCTPGVIKQEKLGPVYCQGSFSGANIIGNKMSAISVHGVSTSGGQ 331
XP_001510749 251 PDTKPKITEHGELLLPS-PSVQMPQVKMEKEDFIELCTPGVIKQEKVGTVYCQAGFPGANILGNKVSAISVHGVSTSGGQ 329
XP_003217421 251 PDTKPKINESDDF-LTS-STMQMPQVKTEKEDFIELCTPGVIKQEKIGTVYCQANFPGSNMLGNKTSAISVHGVSTSGGQ 328
XP_015149519 250 SDTKPKINDRGDL-LPS-SKMPMPQVKTEKEDFIELCTPG-IKQENVGPIYCQANFSGSNMLGTKVSAISIHGVSTSGGQ 326
XP_014343931 246 TNTSQSTNNECGNLFIPdLSSQLSQIKSDKEGYIELLTPGVVKQETLGRSYCQANLTSAAS-TTANSSISIHGVNTSGGQ 324
Q501U9       229 VSGSNTLNGTASSSLSTaNTSILPNIKVEKDSIIQLCTPGVIKQENTGASYCQGGLHSTP--------INICGVTTSSGQ 300 zebrafish
Q5R9P5       331 MYHY--DMNTASLSQ-QQ-DQKPIFNVIPPIPVGSENWNRCQGSGD-DNLTSLGTLNFPGRTVFSNGYSSPSMRPD 401 Sumatran orangutan
XP_001368983 332 MYHY--DLNTASLSQ-QQ-DHKPVFNVIPPIPVGSENWNRCQGSGD-DNLTSLGTLNFTSRSVFSNGFSSPGMRPD 402
XP_001510749 330 MYHY--DLNTASLSQ-QQ-DQKPIFNAIPTLPGSSESWNRCQGSGD-DSLTSLGTLNFAGRPVFSNGYSSPGMRPD 400
XP_003217421 329 IYHY--DLNMASVTQ-QQ-DQKPVFNAIPSHPAGSENWNKCQGAGD-D-LSPIGALNFPGRSIFSNGYSSPGIRSD 398
XP_015149519 327 MYHY--DLNTASLSQ-QQ-DQKPIFNIIPSLPAGSENWNRCQGSGD-EALAPLGTLNLSGRPAFSNGYSSPGLRSD 397
XP_014343931 325 MYHY--DVNAGAVSSaQQpDQKPIFNFIPPVSTIAENWNRCQGSGAtNSTPPLGNVNASGRSGFASSYPSPGTRTa 398
Q501U9       301 SFLFgnSSPTAVVGL-QK-DQKPDFNMYTPLTSSGDGWSRSQGFGNvSGMQQRASLCFSKN--FS---SSPYSRPE 369 zebrafish
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