5SVL


Conserved Protein Domain Family
P2X_receptor

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pfam00864: P2X_receptor 
ATP P2X receptor
Statistics
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PSSM-Id: 459968
Aligned: 66 rows
Threshold Bit Score: 322.965
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5SVL_A            7 FTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEK-AYQVRDTAIeSSVVTKVKGSGL---------------YA 70 
CDS40794         17 FDYETQKVVQINSFKIGFTYRLIQLGIVLYVVFWVMYYEK-GYQAFDEAV-SGVTAKLKGIAFsnst--------ksnIG 86 
CDS42078         11 FTYETPKMVEITNYKIGIFHRLLQIAITVYVVCWVLIYDK-GYQENDEVM-SSTVTKTKGLMVerwaqn-------eedv 81 
jgi:OSTLU_32638   4 LSYTTQKSVVIRSWRLGALYYAIVGVVLSY-VGWYLVYLKhGYQLRSQAV-GNIGLKIKGQAVlrd---------aatGL 72 
XP_001743535     18 LEYDTLKTVHIRSKKVGLIFRLLQITILAYVVGYGIIYQK-GYQEVDSAV-STVLTKVKGIAItcdntdissmndcvpGD 95 
XP_003384136     19 FEYDTPKFVHIRNKKVGLLNRLVQLAIVGYIIGYGIVWEN-GAQDKEPVQ-SVVTTKVKGVSVlnatrqf--mtdcneWP 94 
EFX89098         12 FWYETPKVVHIRSKKVGILGRFLQLCVLSYIVGYVMVYNK-GYQEFANVE-SAVVTKVKGVAFtntnk------nipeIY 83 
EDO41363         13 LEYNTSKIVHIKSKKVGLINRLIQLAIIGYIIGYVIIYKK-GYQEVEKPY-SSVTTKLKGTSFtnltgn---esfplyGG 87 
XP_004994999     18 LEYDTLKTVHIKSKKVGLIFRILQLVILGYIIGYAIIWQK-GYQAADQAV-STVYSKVKGVAVtcndlnvtsirncsdSD 95 
NP_945336        13 FNYTTVRYVVTQNKIVGLLYRFFQLIIMCYLIGWVFVTKK-GYQVVDDTIeSSVVTKVKGIARvnt------------tf 79  zebrafish
5SVL_A           71 NRVMDVSDYVTP-PQGTSVFVIITKMIVTENQMQGF--CPE------SEEk--yRCVSDSQ-CGPERLP--GGGILTGRC 136
CDS40794         87 AIVWDAADYVIP-PQQRSAFFVMTNLVTTSGQTLGT--CEEsh--dvAGN----DCKSDKD-CEAGRIVmvGNGVQTGIC 156
CDS42078         82 aiISDAADIVNP-PLENNAFFVTTHRILTPRQTSSR--CPGi----rNSKk--sSCGRDGD-CEKMQLSlsEAGARTGKC 151
jgi:OSTLU_32638  73 ETVYDANDLVIYePSG---FFVATALMTTL-QARGR--CPGm-----DDDe---ACTEDASiCRAGAFSa--sGRMTGAC 136
XP_001743535     96 LRVWDTPDYIKP-AQENDAFFVVSNSIQTSKQTQRAegWDEdpaapvTGSasafNCTSDAD-CP--RFAtsRNGALTGEC 171
XP_003384136     95 --ILDHVDLIVP-AQEPNSFFVTTNLWATCNQKYGV--CPEls--tiPDA----VCLTNDS-CPPGIIYrtGNGVTTGEC 162
EFX89098         84 RRIWDTSDLIVP-PSENDAFFITTNIIITPNQTRGA--CSEdp--dvYGA----LCDSPQN-CIRGQSLpiGNGAMTGRC 153
EDO41363         88 PFVWDQADYVIP-PEENDAFFVATNMVITPDQRQGT--CPEsp--diANV----KCTRDEN-CTRMEETsyGHGFQTGKC 157
XP_004994999     96 IRVWDTADYVIP-PQESNAAFIVTNSVQTSNQTQQPggWPEdpdastKGSqrayTCEKNAD-CEAVRFSpsRNGAVSGKC 173
NP_945336        80 SDLWGPEEYVIP-DHGGKFLFVVTNFIETPNQTLTT--CPEsp--svPFS----TCTHDDN-CTEGEAVraGNGIKTGTC 149 zebrafish
5SVL_A          137 vn--ySSV--LRTCEIQGWCPTEVDTVE----------TPIMMEAENFTIFIKNSIRFPLFNFE--KGNLLPNl-TARDM 199
CDS40794        157 vpstrKAN--LSVCEIYGWCPTEHDVLPn---------DFILANAPNFTVMLKNSIEFPQYHVK--RRNILGWm-DKHFL 222
CDS42078        152 vd--fHDG--KGVCEIYAWCPLENDTIVlsy-----nlQTRFEMISNYTVYIKNDIEYPKFHIK--RRNRDAWv-SEKPL 219
jgi:OSTLU_32638 137 vd--aGGSsgEKRCEIEGWCPGEPEDDRv----------NVLENVGNFTVFTRISVEFPGIPNKkgDGNLLW-------- 196
XP_001743535    172 -----NTT--TERCRIYGWGPVESKDEDdrattdglfyARHMPAVKNFTVYIKNTVFFQRFGAKfgSTDESDK--VDVY- 241
XP_003384136    163 tg-------fNETCQIRGWCPVEDENDTlt-------dEGPIIDTKDFTVLVKNSISFPKLDSSyrVRNIPERanNKSYL 228
EFX89098        154 ipsdaNSS--VNVCEIFAWCPIEQDIFPlg------tdRPLLEETADFTVLIKNFIEFPTFGKTfrRRNIMKDa-NKTYL 224
EDO41363        158 vpsdqEKG--IKVCEVFAWCPVELDITPm----------PQFPSLKNFTVLIKNTVQFPSFGVS--KRNIAPDa-DTSTL 222
XP_004994999    174 -----DLA--TKRCMVYGWGPVELSKDDdasq--vlgyPRQMPQVKNFTMFIKNTIFFPHFQRKfgNTGLGNS--SASYL 242
NP_945336       150 rk-tdGNE--TNTCEIYGWCPTEKPRRe---------aATMLREAENFTVYIRNFIKFSQFNLS--KTNILKEg-YPSYI 214 zebrafish
5SVL_A          200 KTCRFHPD-KD--PFCP-----ILRVGDVVKFAG-QD--FA-KLARTGGVLGIKIGWVCDLDKAWD-QCIPK--YSFTRL 264
CDS40794        223 STCRYNPN-KEklKYCP-----IFRLADIMEYTE-AE--NK-QIWNKGGMVSIHIEWNCNLDYNEE-QCLPK--YIFRRL 289
CDS42078        220 GSCRYNPS-DEldKYCP-----IFRLGTIFEEVG-LK--PS-ALT-RGGVIGIIINWDCNLDWGAG-NCKPS--YSFTNL 285
jgi:OSTLU_32638 197 ---------TNlnGTEPtmgwnLWTLNDLLASGG-MR--VE-DIAKKGWDGRLDVQFDCDLDRGIE-SCAPKtpYKVRQV 262
XP_001743535    242 -TCTWSPTgLE--RHCP-----IFKIDTILNEAGiTD--FEnQAMRNGALITIQVNYDCNLDSSAH-TCSPT--YKFTRL 308
XP_003384136    229 SGCQFDPD-SEmgLFCP-----IFSLKQIVDMINsSDgyYE-SLATKGAVVGLEISWDCNLDRSPT-HCVPK--YSARRL 298
EFX89098        225 QSCHYNQE-RD--PFCP-----VFRIEDIVSFAG-EN--FT-QLAIRGGVIVISIDWNCNLDLDFLeFCKPI--YSFRRA 290
EDO41363        223 KSCQYDKD-TS--PLCP-----IFRLETITKEAG-QD--FN-KLAYKGGVIGIIITWNCDFDSLLY-SCKPV--YSFRRL 287
XP_004994999    243 KSCLWNES-TD--RYCP-----VFRIEDILSAAGvKS--FEqDVMMAGAVITVQIRYDCNLDKNVE-TCAPE--YRFTRI 309
NP_945336       215 KTCLHDEI-HH--PYCP-----VFRLGDIVSKAG-YR--FE-EVAAKGGSIGIVIKWSCDFDMDTS-DCHPQ--YSFMSM 279 zebrafish
5SVL_A          265 DSVseKSSVSPGYNFRFAK--------------YYKmeNGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTS 330
CDS40794        290 DDF--DNPVGKGWNFRFSQ--------------HYMe-GNVRKRNLIKAYGIQFFITVYGKGGRFHLLTFSMNLGSGLAL 352
CDS42078        286 DVD---NDGNSGFNFRYAY--------------RYRe-NGTLYRDLVKAIGLRFSIFVHGQAGRFSIIPLLLNLGSGLAL 347
jgi:OSTLU_32638 263 TDSe-INTLSKGYNIRWVSahnvgepapmqgvtYNQtgNSKDVRLLVKGYGPRIRFAVDGVGRKFDVLALSTTVGAGVAF 341
XP_001743535    309 DTK---SDLSAGYNFRFAN--------------YQId---PPARDLYKVYGLRFVFVVSGTAGRFSMVPLLVALGSGLGL 368
XP_003384136    299 DNP--NAQISNGFNFRYPR--------------YYRdqNGDDVRDVWKVYGIKFEIVVTGEGRKFSFTTLVLALGSTIAL 362
EFX89098        291 DDP--NTNIAPGWNFRHAN--------------YHEe----NRRTLVKSYGIRFVIEVRGQGRKFNILPTMLNIGSGLAL 350
EDO41363        288 DNA--NAPIAKGYNFRHAN--------------YYVk-NDTLHRTLFKAYGIRFVVTVTGQGGKFNVVPLFLNLGSGLAL 350
XP_004994999    310 DEP--NNTLSNGFNFRFAR--------------YAI--GEVPSRDLYKVYGLRFVFIVSGTAGKFDFVPLLVTFGSGLGL 371
NP_945336       280 GSS---TPVTAGYNFRFAR--------------YSSdaAGRTHRNLYKVYGFQLNVMVFGTASQFSIIHTIINVASVLTL 342 zebrafish
5SVL_A          331 VGVGTVLCDIILLNFLKG-ADQYKAKKFEE 359
CDS40794        353 LGIATVLCDTIVLNITRK-REVYRSARIDL 381
CDS42078        348 LGMAPTICDIIILNIVGS-KNVYKDAKFEV 376
jgi:OSTLU_32638 342 LGIASLVVNAVMMYGSGKkSKQYENWLFAE 371
XP_001743535    369 LGLATVIADLLVTKCIRN-ANVYYGLKYQV 397
XP_003384136    363 LAIATTVTDVIALYLLKK-GTYYREKKYQK 391
EFX89098        351 LGVTTVVCDFIILYFTKK-RMFYKGVKYLL 379
EDO41363        351 LSIATVLCDVVVLYVLRR-KEFYREKKYQY 379
XP_004994999    372 LSLATIVADLLVTKCLRN-AEFYYDRKYEI 400
NP_945336       343 MAVGSYICDVILLFMVKK-----KYAKFES 367 zebrafish
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