Conserved Protein Domain Family
FYVE_2

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pfam02318: FYVE_2 
FYVE-type zinc finger
This FYVE-type zinc finger is found at the N-terminus of effector proteins including rabphilin-3A and regulating synaptic membrane exocytosis protein 2.
Statistics
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PSSM-Id: 426716
Aligned: 15 rows
Threshold Bit Score: 138.659
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_012405441    8 SKLTDEEAKHIWEVVQRDFDLRKKEEERLEELKGKIQKESTKKEVLSDQAQLNETHCGHCLQPYRFLLNSK--RQCLDCQ 85  
XP_013013155    8 SLLTDEEAQHVWQVVQRDFALRTQEEERLARLKGKIRWESSKRELLSDTAHLNETHCARCLQPYRLFVSGK--RQCLDCG 85  
XP_023413469    8 SKLTDEEAKHIWEVIQRDFDLRRKEEERLEGLKGKIKKESSKRELLSDSAHLNETHCAHCLQPYRLLVNSR--RQCLDCH 85  
XP_001512824    8 SKLTDEEARHVWEVVQRDFDLRKKEEARLEKLKGKIKKESTKRELLSDQAHLSETHCIHCLRPYKFLINSK--RQCLVCL 85  
BAD07031       49 GSITAAEQEHIQKVLAKAEESKSKEQQRIGKMVDRL--EKMRRRATGN----GVTHCLLCHTEFGLLASKSyaAMCVDCR 122 
XP_017946079   44 EELTDEEKEIINRVIARAAKMEEMEQERIGRLVDNL--EDMRKTVTGD----GVNRCILCGEQLGLPGTKC--VVCEDCK 115 
Q768S4         45 QCLSPGELEIILQVIQRAERLDILEQQRIGRLVERL--ETMQRNVMGN----GLSQCLLCGEVLGFLGSSS--VFCKDCR 116  house mouse
XP_011889572    8 SGLTDDETEHVLQVVQRDFNLRKKEEERLSELKQKLDEEGSKCSILSKHQQFVEHCCMRCCSPFTFLVNTK--RQCGDCK 85  
XP_011614603    8 SGLSDNEAEHVLQVVQRDMKLRKKEEARLSELRQELDEEGSRCLLLSRQRCFNQRCCIRCCSPFTFLLNPK--RQCHDCR 85  
A8T6P4          8 SGLSNNEAEHVLRVVQRDMQLRKKEEERLSEMKQELEEEGSRCLLLSKQQKFNEHCCIRCCSPFTFLLNPK--RQCLDCH 85   zebrafish
XP_012405441   86 LYTCKK-CGTY--------NRREQGWVCDPCQLARVV-KTGSLEWYYEHV 125 
XP_013013155   86 LFTCKH-CSHA--------HPEVRGWLCDPCHLARVV-KIGSLEWYYEHV 125 
XP_023413469   86 LFTCKG-CGSA--------HPREQGWLCDPCHLARVV-KVGSLEWYYKHV 125 
XP_001512824   86 LHTCKC-CSSF--------TQPEGGWVCHPCQLARVL-KIGSLEWYYQHV 125 
BAD07031      123 KYVCQRnCGVEttdvnqttGKVETVFLCKICSEAREVlWKKSGAWFYKEM 172 
XP_017946079  116 KNVCTK-CGVQs------nSRPHSIWLCKICSEQREV-WKRSGAWFFKGF 157 
Q768S4        117 KKVCTK-CGIEas-----pGQKRPLWLCKICSEQREV-WKRSGAWFYKGL 159  house mouse
XP_011889572   86 FNVCKS-CCSY--------QKHEKAWVCCVCQQARLL-RAQSLEWFYNNV 125 
XP_011614603   86 YNVCKA-CRAY--------NKQERSWLCSACQKSRLL-KTQTLEWFYNNV 125 
A8T6P4         86 YNICKS-CCSY--------SQSERGYICAACQKSRHL-RTQSLEWFYNNV 125  zebrafish
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