Conserved Protein Domain Family
PPDFL

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pfam15060: PPDFL 
Differentiation and proliferation regulator
Pancreatic progenitor cell differentiation and proliferation factor-like protein (PPDFL) is alternatively named Exocrine differentiation and proliferation factor-like protein. PPDFL regulates exocrine cell fate. This protein is highly expressed in exocrine progenitor cells which eventually differentiate to form exocrine pancreatic cells.
Statistics
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PSSM-Id: 464477
Aligned: 17 rows
Threshold Bit Score: 149.245
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5PR01         1 MAAIPSSGSLVATHDYYRRRLGSSSSNSSGGSAEYPGDAVPHSPGLPK-ADSGHWWASFFFGKSTLPFMAA-VLESPEHS 78  Norway rat
XP_003421835   1 MAAIPSSGSLVATHDYYRRGLGSTSSNGSCGSAEYPGEAIPHRPGLPK-ADPGHWWASFFFGKAAVPFMAT-VLESPVHS 78 
XP_003757650  96 MAAIPSSGSLVATHDYYRRRLGSTSSNSSCGSAEYSGEVIPHHPGLPK-SDPGHWWASFFFGKSSHPFMTT-VLESPEHS 173
A4IGU9         1 MAAIPSSGSLVATHDYYRRRLGSTSSNSSCGSVDYSGEVIPHHPGLPK-SDPGHWWASFFFGKSTHPSMTT-VSESPESS 78  tropical clawed...
XP_010720702   1 MASIPSSGSLMATHNYHRRRLSSTSSNSSCSSSEYAGEVIPHHPGLPK-SDPGQWWASFFFGKTNHPAMTT-VSESPESL 78 
XP_005993531   1 MASIPSSGSLIATHDYYRRRLGSTSSNSSCGSIEYSGEVIPHPPGLPK-SDPGHWWASFFFGKPNHPTMTT-VSEFPESS 78 
XP_006639676   1 MAAIPSSGSLIATHDYYRRRLGSTSSNSSCGSSEYAGEVIPHHPGLPKhQDPGHWWSSFFFGKHNQPTMTT-LTESPQNS 79 
Q6PFP3         1 MAAIPSSGSLIATHDYYRRRIGSTSSNSSCSSSEYTGEVIPHPPGLAR-QDSGHWWSSFFFGKQNQMGTPN-GFESQQKT 78  zebrafish
Q6PBI2         1 MAAIPASGSLVATHDYYRRRIGSTSSSSSCGSSEYSGEVIPHHPGLPK-QDSGHWWSSFFFGKQNLPGMGTvAEEAQQKS 79  zebrafish
XP_004841132   1 MAAIPSSGSLVATHDYYRRRLGSASGSSSCGSAEYPGEAVPHHLGLPK-ADPGHWWASFFFGKPIVPFMAT-VLESPEHS 78 
Q5PR01        79 aESPQASRSPISCGLAPETMKKQPVMHPSQTNS 111 Norway rat
XP_003421835  79 -GPLQTPSGMITCDLTQGTMTKQPGSPPATPAP 110
XP_003757650 174 -GTFQVAHGTITCDLAQEAMRKRHVSEPSKTSP 205
A4IGU9        79 -GTFSISNGLIPCRLAQESLQKQKVGDPKSDSS 110 tropical clawed frog
XP_010720702  79 -GALPLPVGPLACGLVPGAGRRRHASEPGIGPS 110
XP_005993531  79 -KSVSVVNGKINCGLAQEVMRKRHASEPSKSSA 110
XP_006639676  80 -GTFSVTNEKVTCGLAQEVMKRQL----SDASE 107
Q6PFP3        79 -GTYTVTNGQVTCVAREIVMKRHL----SESSD 106 zebrafish
Q6PBI2        80 -GVVSVTNGQVTCVAREMVM-RQA----SESSD 106 zebrafish
XP_004841132  79 -EAPQAPSSVVTSGLASETTGKQPLSQPSQANT 110
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