Conserved Protein Domain Family
bS6_mito

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cd15465: bS6_mito 
Mitochondrial Ribosomal Protein (MRP) S6
bS6_MRPS6 is one of the proteins of the small subunit of the mitochondrial ribosome. Mitochondrial and chloroplastic ribosomes are similar to bacterial ribosomes. The ribosome is a ribonucleoprotein organelle that decodes the genetic information in messenger RNA and forms peptide bonds to synthesize the corresponding polypeptide. Ribosomes consist of a large and a small subunit, which assemble during the initiation stage of protein synthesis. Prokaryotic ribosomes consist of three molecules of RNA and more than 50 proteins. The small subunits of bacterial and eukaryotic ribosomes have the same overall shapes (with structural elements described as head, body, platform, beak and shoulder). Mitochondrial and chloroplastic ribosomes synthesize proteins that are involved in oxidative phosphorylation (ATP generation) and photosynthesis. bS6_MRPS6 is one of the fourteen mitochondrial ribosomal proteins that is known to have significant sequence homology with their bacterial counterpart.
Statistics
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PSSM-Id: 275386
Aligned: 81 rows
Threshold Bit Score: 69.869
Created: 31-Mar-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
rRNA bindingS18 interface
Feature 1:rRNA binding site [nucleic acid binding site]
Evidence:
  • Comment:The 16S ribosomal RNA and its associated proteins form a part of the functionally relevant body of the 30S ribosomal subunit

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1         #                                             #   #                  #  ##     
XP_006862612   3 RYELALILKAm-qRPETAAALKRTLEALMDrGAIVRNLENLGERALPYRISAHSQkHTRGGYFLVDFHAPPTIVENIMEH 81  Cape golden mole
ESO89110       3 TYELALIVRAaleRPQLANCLKRTCTYILDrGGVVRQMENLGNKNLPYIISSHGHrHTEGNYFTVDFDLSPNQMSTLRKV 82  owl limpet
P82932         3 RYELALILKAm-qRPETAATLKRTIEALMDrGAIVRDLENLGERALPYRISAHSQqHNRGGYFLVDFYAPTAAVESMVEH 81  human
NP_001090858   3 RYEMALILKAm-qRPETAATLKRTIEALFEgGAVVRNLENLGEKALPYKISKHNLrHTRGGYFLIDFHAPPTIIPSMLDH 81  western clawed ...
NP_001026657   3 RYELALILKAm-qRPETAAVLKRTVEALMErGAIVRNLENLGERALPYKISKHNHrHRRGGYFLVDLEGPPSIVSTMMDH 81  chicken
NP_001038921   3 RYELYMVLKAm-qRPETAAVLRRTVETLFErGAVVRSLENLGERKLPYKISKHDSrQSHGGYFSIDFHASPNIVSGLLNH 81  zebrafish
XP_002730679   3 RYEMALIFRAl-nRSETISAMKRVGESVIErGGQIRTIENLGEKDLPFKMVAHSQgYRRGRYIVMEFDGKPSIVSSMVEY 81  Saccoglossus ko...
ESO12414       3 QYELSVIFKAl-gRMDLSKAIKRTSETILNsGGVIRSFDNVGLRKLPYKMFKHGNrYDEGNYYIIKFDCPPNIVPDLKAH 81  Helobdella robusta
XP_005108269   3 TYELAVIFRAl-qRPELSQAVKRCCTNILDkGGIIRGMENLGEKPLPYRMRAHGSrFYEGNYILIQFDGATSLPTQLHEE 81  California sea ...
ACO14971       3 TYELNLVLRKm-aRPEVVTALQRTAALVMK-DGYIRKMVSLGGRRLPQVQEYKGErHSEGTYFLMKVDLPVESVVPVLSE 80  Caligus clemensi
Feature 1         #      #  ### 
XP_006862612  82 LSRDiDVIRRNVVKH 96  Cape golden mole
ESO89110      83 LLQDsDVVRPGIVHK 97  owl limpet
P82932        82 LSRDiDVIRGNIVKH 96  human
NP_001090858  82 LSRDiDVIRPTILKQ 96  western clawed frog
NP_001026657  82 LGRDiDIIRRAFIKY 96  chicken
NP_001038921  82 LERDvDVLRPTVVKK 96  zebrafish
XP_002730679  82 LRRDvDVIRPAITKL 96  Saccoglossus kowalevskii
ESO12414      82 FNLDlDIVRPKILRQ 96  Helobdella robusta
XP_005108269  82 LRRDtDVIRRNVYTD 96  California sea hare
ACO14971      81 LKRDgDFLRKQFVGV 95  Caligus clemensi

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