6KN7


Conserved Protein Domain Family
Troponin
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pfam00992: Troponin 
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Troponin
Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). this Pfam contains members of the TnT subunit. Troponin is a complex of three proteins, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). The troponin complex regulates Ca++ induced muscle contraction. This family includes troponin T and troponin I. Troponin I binds to actin and troponin T binds to tropomyosin.
Links
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Statistics
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PSSM-Id: 460018
Aligned: 84 rows
Threshold Bit Score: 39.8549
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6KN7_T          7 KRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR-AeraEQQRIRNEREKERQNRLAEERARREEEENRRKAEDE 85 
XP_012019000   60 KRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRaEr-aEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDD 138
CAG02062       71 KRMEKDLLELQTLIDVHFDQRKKDEEELISLKERIERRRaEr-aEIQRVRAEKEKDRQNRIAEERHRKEEEEAKKKADDE 149
17_pfamImport   1 KRLEKDFNELQSLIEMHFESRQKEEDELVALKLRIERRRsEr-aEQLRIRTEREKERQTRMTEEKLRKEEEEARRKAEED 79 
Q8AVB1        101 KRVEKDFNELQSLINLHFTTRQKEEDELVALKNRIERRRtDr-aDQQRIRTERDRERQARLAEERARREEEAAKLRAEED 179 zebrafish
1_pfamImport    1 RRLEKDFDDLQTLIESHFSARQKEEEELLALRGRIERRRsDr-aEQQRVRAERERERAARLAGERARREEEAAA----ND 75 
CAG12485      140 KRQNKDLIELQSLIDAHFECRKKEEEELIALKERIEKRRaEr-aEQQRIRAERDKERQARREAERQRKEEADAHRKAEDE 218
XP_004225995   46 KRMEKDMVELQGLINAHFEQRKKDEEEIEELRVRIEERKsKr-aEQIRIRQDRERERMAQEREERKRKEEEEESKRQEEE 124 vase tunicate
RVE56568      114 KRLEKDYNDLQSLIELHFSSRQKEEEELVSLRNRIERRRaDr-aEQQRVRAEQERERQVRVAEERSRREEEAAKQRAEDD 192 javanese ricefish
PWA21945       81 KRMEKDLLELQTLIDVHFEQRKKEEEELIGLKDRIERRRaEr-aEQQRVRAEKERDRQTRIAEERQRKEDEEAKKRADDE 159 western mosqui...

6KN7_T         86 ARKKKALSNMMH-FGGYIQKqaqterksGKRQTEREKKKKILAERRK-VlAIDHLNEDQLRE 145
XP_012019000  139 AKKKKVLSNMGAhFGGYLVKaeq---krGKRQTGREMKVRILSERKKpL-NIDHMGEEQLRE 196
CAG02062      150 AKKKKVLSGMGAnFGGFLAKaet---rkGKRFTGREIKKKTLAERRQpL-AIDSLREDGLRQ 207
17_pfamImport  80 AKKKKAFSNMs--FGGYLQKvek---kaGKKLTEREKKTKILKERRRpL-NIDHLNQEKLAE 135
Q8AVB1        180 ARKKKILSNKg--YGGFLQKvdq---kkGKKLTEREKKTKCLLERRKpL-NIDHLNQEKLGE 235 zebrafish
1_pfamImport   76 AKKKKTFTSKs--FGGY-QKadq---rkSKKLTAREEKKKALTERRRpL-NIDHLSQEKLAD 130
CAG12485      219 AKKKIALSNMGSgYSSILQRaeq---krGKRLTEREKKKKIMADRVKpL-NVDNLSDDKLRE 276
XP_004225995  125 ARKKAAIANMSLhYGGYLARaek--nkpNKRQTDREKKKKLLADRRKpL-NIDHLSDDKLKE 183 vase tunicate
RVE56568      193 AKKKMVFSNK-S-FGGYLQKvdq---kkGKKLTAREEKKKALMERRKpL-NIDHLNQEKLAE 248 javanese ricefish
PWA21945      160 AKKKKVLSNMGAhFGGFLAKeeq---rrGKRQTAREIKKKTLAERRKpL-SIESLKEDGLR- 216 western mosquitofish
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