Conserved Protein Domain Family
UPF0515

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pfam15135: UPF0515 
Uncharacterized protein UPF0515
This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. There are two conserved sequence motifs: PLT and HSC.
Statistics
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PSSM-Id: 464521
Aligned: 9 rows
Threshold Bit Score: 226.227
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
A7YY07        18 REKFHGLI-EIDTAVL------LMRRYVKNHRMVAMWIALMADnd---rELDEEDQAALNNDPVAK-------------- 73  zebrafish
XP_012397400  19 REQFHGSI-SVEKANV------LMERYNHNHDLVSSWLVKQMD------ELRLENEDGSQADPAAQ-------------- 71 
XP_007488636  19 REKFHGHV-SVKKANV------LMQRYNDNHNLVASWLVKQMN------DIRPEEGDGHQPDPIVQ-------------- 71 
Q32L09        16 REKFHGKV-SSKKAGT------LMRKFGSDHTGVGRSIVY---------GVKQKDGQELSNDLDTQ-------------- 65  cattle
XP_004345282 113 RRKNNNR--PADSAGAaqprrgLPRRRRGGAPVAALAAANAPVaaagdfDLGDAPQGALVDFGAMR-------------- 176
A0JP89        19 REKFHGKV-TLETAVA------LMRRFTNNHDQVCKYIILCMDn-----DTDLDVRNDLRNDPVAR-------------- 72  tropical clawed...
XP_016852544  19 REKFHGKV-DIPDAVV------LMRQFSNNHDLACKRIILCKDelddepDMDPEGRGRLGNDPVAQ-------------- 77 
2_pfamImport   1 REQFYGKV-SIEVATV------LMRRYGNNHQLVAMDIILMKDr-----GLDEEDMMCLKRDAVVR-------------- 54 
XP_014341480  19 mEKFHAKViTVEKATV------LMRRFANNHDLVARHIILCKDql----------gdKLTVYQNAAfglnvverirneeq 82  coelacanth
A7YY07        74 ---------------NVIMKLKaeeqqqeekhakssssgssgagpsakakkqpsdDRDITELGTR-LRVLPLTMENKRMF 137 zebrafish
XP_012397400  72 ---------------DGQNALK---------------------------------DRDIQEVAIT-MNLLPLTEKNLRML 102
XP_007488636  72 ---------------DRQNVLq---------------------------------DRDIEEVAAT-MS-LPLTEKNLRML 101
Q32L09        66 ---------------DPPEDMKq--------------------------------DRDIQAVATS-L--LPLTEDNLRMF 95  cattle
XP_004345282 177 ---------------Nglppn------------------------------gpsaPSSVSSVASSkASRKPLTERNVAIK 211
A0JP89        73 ---------------NVINKIKsddqka----------------------kempkDKDIKDLAKR-MNTLPLTEKNLKMF 114 tropical clawed...
XP_016852544  78 ---------------KVMDKLKkeeerkk--------------------qasdneNDKIKDIAQQ-LKVLSLTEENLRMF 121
2_pfamImport  55 ---------------NVVQKLQaeeqsqelapgpapa---pprgpqiaqkrtpvdDGDIKSLGTG-IRVHVLVCTFITLW 115
XP_014341480  83 qqqqqqqqhpqappqNPRNNIDq--------------------------------DLGAQEIIDG-MRRLPLTQRNLRMF 129 coelacanth
A7YY07       138 DQAQANQIPSDTHQFACESCDRDWWRRVPQR----KRVSRCHRCKKKNDPVP-PDRMWGIAEFTCPNCTRNFKGF-GRMD 211 zebrafish
XP_012397400 103 DDAQRGQIGKEDCQFACRMCDYMWWRRVPER----KKVSQCRKCKVKYDPVP-KDKMWGKAEFHCLQCGHTFTGF-AQMG 176
XP_007488636 102 DDAQKGHIAKEDCQFACQPCDFMWWRRVPER----KKVSRCRKCKVKYDPVP-KDKMWGIAEFQCLQCGHTFKGF-AQMG 175
Q32L09        96 QRAQEDLIPAVDRQFACSSCDHVWWRRVPQR----KEVSRCRKCRKRYDPVP-SDKMWGVAEFHCPKCRHNFRGW-AQMG 169 cattle
XP_004345282 212 DRSHYQL-----YMFGCEGCSMLWYKKCAPI----NPVSPCRGCNTRYDPIPiGSEPVGLGFFRCSKCKHQWTSCpAARN 282
A0JP89       115 NDAAENRIPSRDRQFACKECDFVWWRRVPQR----KEVSRCHRCRKKFDPVP-ENKMWGIAEYHCPVCRRMFRGF-GQIE 188 tropical clawed...
XP_016852544 122 NQAKNNQILTRDRQFACQPCDIMWWRRVPKR----KEVSRCHRCGTCYDPVP-CKKMWGYAEFECPSCQRTFKGF-GQME 195
2_pfamImport 116 NSISAHITHWNXYYYYY----YYYYYNIPPRfpcvSQVSRCHGCRTKYDPVP-PNLMWGLAEFHCHRCNRTFRGF-GRMD 189
XP_014341480 130 DDANRNLIPSVDKLFACPICDHIWWRRVPQR----KQVSRCRTCKRKYDPVP-SDQMWGAAEFNCLGCHRVFRGY-GQME 203 coelacanth
A7YY07       212 GRSPCYGCRSAIY----PMKILPPR--RKnmmPGPKQR-NQHSCFAEDCYHRMEPHVPGTECVHPHSRQKNRKPRVVYPS 284 zebrafish
XP_012397400 177 TSSPCFRCGSPVL----PSRILPPR--RS---QTERVTkNTHRCSAENCYNRQGPYTPGACCVHPKTRQQNNMPTVLFPS 247
XP_007488636 176 NPSPCYSCGNPVL----PNRILPPR--RP---QNERSRkHEHSCFAETCYNRQGSYEPGTSCVHPKSRKQKHMPVVLFPS 246
Q32L09       170 SRSPCYGCGFPVY----PTRILPPRwdRD---PDRRST-HTHSCSAEDCYNRREPHVPGTSCAHPKSRKQNHLPKVLHPS 241 cattle
XP_004345282 283 VSQPCFGGKCVMLhheyPYKVLPRQsmRShtdETQRKSdNKHSCAA--C---------GGEGQCPLRRRGDVF------S 345
A0JP89       189 VSSPCYVCRNPVL----PSCILPPR--RN---QGPRTR-NTHSCLAENCYNRRVPFVAGLQCAHPKSRIMNQLPKVLHPS 258 tropical clawed...
XP_016852544 196 VPSPCFGCHNTVF----PSRILPPR--RT---QGPRSR-HQHSCFAEDCFNRREPHVPGTHCVHPQSLRRNRLPKVLFPS 265
2_pfamImport 190 VGSPCYTCHIPIL----PIRILPPR--RS---NGPRQR-NQHSCCAEDCYNRQEPHVPGTECVHPRSRTRNHKPRVVNPS 259
XP_014341480 204 VPSPCYMCGTRVT----PSRILPPR--RS---NGPRNR-NPHSCCAEDCHNRREPFMPGTHCVHPRSRLRNGLKKVVSPS 273 coelacanth
A7YY07       285 PAHISSGSTVNTCLSQGSLIE-SINELILDDI 315 zebrafish
XP_012397400 248 AVHESTGSTVATCLSQGSLIE-DLDNLILEDL 278
XP_007488636 247 AVHDSSGSTVATCLSQGSLIE-DLDSIILEDI 277
Q32L09       242 NLHISSGSTVATCLSQGGLLE-DLDNLILEDL 272 cattle
XP_004345282 346 KAHVSAPGSIGCSSSPGS----ERNWLSDENY 373
A0JP89       259 EPHISTGSTIATCLSQGSLTEnDIDDIILDDI 290 tropical clawed frog
XP_016852544 266 EEHDSTGSTVDTCVSQGSLQV-DLDYLILEDL 296
2_pfamImport 260 PLHASSGSTVATCLSQGSLY--DLYQLIMDDI 289
XP_014341480 274 PDHDSTGSTVATCLSQGSLMEcGVDEIIMEDL 305 coelacanth
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