Conserved Protein Domain Family
BTB_POZ_ZBTB1
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cd18192: BTB_POZ_ZBTB1 
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 1 (ZBTB1)
ZBTB1 acts as a transcriptional repressor that represses cAMP-responsive element (CRE)-mediated transcriptional activation. It also has a role in translesion DNA synthesis, and is essential for lymphocyte development. ZBTB1 contains a BTB/POZ domain, a common protein-protein interaction motif of about 100 amino acids.
Links
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Statistics
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PSSM-Id: 349501
Aligned: 8 rows
Threshold Bit Score: 235.87
Created: 13-Sep-2017
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9Y2K1         3 KPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFM 82  human
XP_007068061   3 STSHSTYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHTTAQLNLSNMKISAECFDLILQFM 82  green sea turtle
NP_999962      3 RPSHSEHVLQQLNNQREWGFLCDCCIAIGDIYFRAHKAVLAACSSYFRMMFIRDQQGSARFDLSNMQISAECFDLILQLM 82  zebrafish
XP_002938842   3 RSSHCSYVLQQLYNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFKMMFINHQNTVSQINLSSIKVSAQCFDLILQFM 82  tropical clawed...
XP_005986447   9 RPSHSDYVLQQLSNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFKMLFINHQSVTTQLDLSNMQIRAEYFDLILQLM 88  coelacanth
XP_007908443   3 RPSHSDYVLQQLNSQREWGFLCDCCIIVNDIYFRAHRAVLTACSSYFRMMFISQQHLTGNLSLSNMNISPECFDLILQLM 82  elephant shark
CAG31630       3 RTSHSNYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHTTAQLNLSNMKISAECFDLILQFM 82  chicken
AAH97608       3 RSSHCSYVLQQLYNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFKMMFINHQNTVSQINLSSVKISAQCFDLILQFM 82  African clawed ...

Q9Y2K1        83 YLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDI 116 human
XP_007068061  83 YLGKIMTAPTNFEQFKVAMNYLQLYNVPECLEDI 116 green sea turtle
NP_999962     83 YLGRIAVDHYEFEELKASMAYLQMYYIPDSLEDL 116 zebrafish
XP_002938842  83 YLGKILHLPENFDQLKQAMSYLQLYVIPECLEDI 116 tropical clawed frog
XP_005986447  89 YLGKIIASPTDFQELKSAMTYLQLYYIPECLEDI 122 coelacanth
XP_007908443  83 YLGKVIGVPSDFEELRTAMTFLQLYYIPKSLEEI 116 elephant shark
CAG31630      83 YLGKIMTAPANFEQFKVAMNYLQLYNVPECLEDI 116 chicken
AAH97608      83 YLGKILHLPEDFDQLKEAMSYLQLYVIPECLEDI 116 African clawed frog
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