Conserved Protein Domain Family
Cortexin
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pfam11057: Cortexin 
Cortexin of kidney
In the middle of cortexin protein there is a single membrane-spanning domain which indicates that this protein may be a membrane protein involved in intracellular or extracellular signalling of the kidney or brain, since it is expressed specifically in the kidneys and brain only. The protein is highly conserved among species. Cortexin is also thought to be important to neurons of both the developing and adult cerebral cortex.
Links
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Statistics
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PSSM-Id: 314086
Aligned: 6 rows
Threshold Bit Score: 97.1647
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_007660884 10 EALSPSlGGPPGPAGLDAEQRTVFAFVVFLLLFLVVLMVRCFRILLDPYSRMPASSWTDHKEGLERGQFDYALV 83 
XP_017832323  9 SSAKMS-VNEVSAFSLTLEQKTGFAFVGILCIFLGLLIIRCFKILLDPYSSMPSSTWEDEVEEFDKGTFEYALA 81 
Q592E4        9 SLAAMS-GSDIMAYSLSLEQKTAFAFVGMLLVFLGLLIVRCFRILLDPYSSMPSSSWGDGLEGLEKGTFEYALT 81  zebrafish
XP_014322778 10 EPLPPS-TGPPAGVGLDAEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRMPASSWTDHKEALERGQFDYALV 82 
ELK11619      9 SPLAPL-GNTLSDSSMSLEQKTTFVFVILLFIFLGILIVRCFRILLDPYRSMPTSTWADGLEGLEKGQFDHALA 81 
XP_010724324 25 ATLVPS-GNVTPDSSMTLEQKTTFAFVILLFIFLGILIIRCFRILLDPYRSMPTSTWADGLDGLEKGQFDYTLA 97
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