2BPC


Conserved Protein Domain Family
DNA_pol_B_palm

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pfam14792: DNA_pol_B_palm 
DNA polymerase beta palm
The catalytic region of DNA polymerase beta is split into three domains. An N-terminal fingers domain, a central palm domain and a C-terminal thumb domain. This entry represents the palm domain.
Statistics
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PSSM-Id: 464318
Aligned: 34 rows
Threshold Bit Score: 117.281
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2BPC_A            62 RIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSess----------kqPKLLHRVVEQL 131 Norway rat
CBJ33393         183 RMPRSEAAEIEAVVTKVAQSICPGVICQACGSYRRGKSHCGDVDVLIRPPEGQEd--------------SPMFDDLIKRL 248
XP_002415548     277 KMPREEAGEIADTVAKAALSLQPGLTVVPCGSYRRGKSMCGDVDVLISHAELSAl--------------DGLLNRLLQLL 342
EDO35929         213 RMPREEAGKIGEVVKAATEIIDPSLLCITCGSYRRGKSTCGDVDVLVSHPDGKSh--------------HGVMGPLLCEL 278
EEN59690         322 RMPREEAAEIERTVREMAESINPDLMAMACGSYRRGKLNCGDVDVLITHPDGKSh--------------KGIFQKVLNGL 387
jgi:MICPUN_59282 525 RIPRDEVEALAGHVEDAVAAVCPGCSVTVAGSYRRGKTSCGDVDVLLCPSEEFIrggsqgapgatvdtvEDILPAVLARL 604
RQO96485         329 RIPRHEVQEMELLLQKTGEEILPGVDILCGGSYRRGKASCGDLDIVITHPDGKSh--------------KGFLTRYVKRL 394
EFJ16643         125 RIPRDEVVDTEKFVRGVVETLAPGAWVNAAGSYRRGKPTCGDVDILITHPDGSSh--------------QDLLARLVQEL 190
XP_002966561     125 RIPRDEVADTEKFVRGVVETLAPGAWVNAAGSYRRGKPTCGDVDILITHPDGSRfts----------lrCCTHSSHLHLL 194
NP_998408        378 RMPRSEANAIEKTVKDAAHSVDPQLLAMACGSYRRGRSTCGDVDVLITHPDGQSh--------------KGVFSKVLHLL 443 zebrafish
2BPC_A           132 QKvRFITDTLS----------KG---ETKFMGVCQLPSe-------------------nDeneYPHRRIDIRLIP 174 Norway rat
CBJ33393         249 VEtGFITDKLTlag-----gpHRpgkSQSFMGICKLPG---------------------Tg--RLHRRVDIKFYP 295
XP_002415548     343 RSsGFLTDGLAv--------pHGtgvPSKYMGVCRIDR---------------------Pg--SKHRRLDVFVIP 386
EDO35929         279 KSsGFLTDDLVsa-------dIEd--QKKYMGVCKLPG---------------------Ed--TKHRRLDIIVVP 321
EEN59690         388 KEtGFLTDDLVtq-------eDNg-eQKKYLGVCRLPG---------------------Eg--RKHRRLDIIVIP 431
jgi:MICPUN_59282 605 RTrGVVTDDLS----------TG---TVSWMGVARLPDsrerlaptttdgaegdgavavVtpkRLHRRMDIKTYT 666
RQO96485         395 KDmKFLREDLIfsthseegtdSG---VDTYFGLCTYPGr------------------------ELRHRIDFKVYP 442
EFJ16643         191 RRiEFIVDGLRvdana-rkggTQ---PDMFMGIFHFQC---------------------K----AYRRIDIKVYP 236
XP_002966561     195 CShQDLLARLGg---------TQ---PDMFMGIFHFQG---------------------K----PYRRIDIKVYP 232
NP_998408        444 HQsGFLTDDLVsh-------eENg-eQKKYMGICRLPG---------------------Ps--QLHRRLDIIVVP 487 zebrafish
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