4HKF


Conserved Protein Domain Family
Acetyltransf_16

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pfam05301: Acetyltransf_16 
GNAT acetyltransferase, Mec-17
Mec-17 is the protein product of one of the 18 genes required for the development and function of the touch receptor neuron for gentle touch. Mec-17 is specifically required for maintaining the differentiation of the touch receptor. The family shares all the residue-motifs characteriztic of Gcn5-related acetyl-transferases, though the exact unction is still unknown.
Statistics
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PSSM-Id: 461616
Aligned: 32 rows
Threshold Bit Score: 219.362
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4HKF_A        10 NALFP----ERISVLDSN-------LSagrkAHGRPDPLPQVTTVIDELGKASSKAQQLPAPITSAAKl-QA--NRHHLY 75  zebrafish
XP_002504713   8 AGLTP----GGVSVWTRD-------AI----VRLPPDEYRAISALIDEAGARSARAQGLPAPITSTDR--LL--EDQRLY 68 
EFJ18369       8 ACLKSgpqgARVTIWDGQklgrlnpAE-----------KEDMRRVIDDMGRLSAQAQKLKVPITDYERirL---GSQALY 73 
XP_008183583   8 KDLAE----GGIAKIDHT-------LTpl-gCEEDENLQKKVAMIIDEMGKASARAQDLKMPITTAEKl-SK--SDHIIY 72 
XP_016663138   8 GKVAT----DEVLKINNT-------LTve-gHEENDDLKNIMRLIIDEMGKASAVSQEFKVPITSANRl-VN--SDHVIY 72 
XP_003247218   9 SNSHV----GQVLKINNT-------LTaegyENNHE-LRNNLRLIIDEIGKSSAIAQHLEFPITSAQKl-LN--SDHVIY 73 
XP_016660281   8 SHIAH----DQIIKIDNS-------LLpvgyQKEDPELQRMISNVLDKMGVASGIAQELKSPITSAEKl-MR--SDHILY 73 
O45100         8 RPILG----PQLVRLDPMrvk--------------qlqDPIVYEAIDNLAKLSAHCLQLRTPLTTCEKl-IN--SDSTLY 66  Caenorhabditis ...
2_pfamImport   1 STLFT----NNIQRLNRAdllkygpRR-----------YWPVSQSIDTLGEMSSKFHGWKRVITKYDKi-VDhdEEQIVY 64 
Q23192         8 STIFT----DNIQRLTRTdllkygpKR-----------YWAVAQSIDCLGEMSSKFHGWKRVITMYDKi-VDhdEEQTTY 71  Caenorhabditis ...
4HKF_A        76 LL-KDGEQn-gGRGVIVGFLKVGYKKLFLLDQRGAHLETE-PLCVLDFYVTETLQRHGYGSELFDFXLKHKQVEPAQXAY 152 zebrafish
XP_002504713  69 LAcSDATRprgGPSVLVGILKVGPKRLFVAKPSGGMEEME-PCCVLDFYVHESSQRGGWGSLLFDAFLQREDRHPARLAY 147
EFJ18369      74 LLtSSGPSk--DVILVKGLLKVGQKNLFIRKECGALVEIN-PLCVLDFYVHVSCQRIGLGRQIFDAMLVHTKKLAYQIGY 150
XP_008183583  73 LL-SEQTNd--ETFVIVGILKMGWKKLYLFDKKGSRSEAM-VYCLLDFYIHETRQRQGYGNKLVEHMLKDNELEAKQLAI 148
XP_016663138  73 MM-TEHKKp--GHFAVVGFLKMGWKKLFLYDKQASRSEAR-VYCLLDFYIHESKQRKGYGIRLIQCMLQDIGLEAKHLAI 148
XP_003247218  74 MM-TEQNTp--ANFAVIGFLKMGWKKLFIYNKQDTCSETL-VYCMLDFYIYESKQRQGYGKRLIEYMLQDMKLHARHLVM 149
XP_016660281  74 LM-TEQTSp--GHFVVVGLLKMGWKKLYLFNKKGSRTEAM-VYCLLDFYIHETRQRHGYGIKLMDYMLKDNQIEARQLAV 149
O45100        67 LSwKYDEEe--KVSRLMGFAKVGRKKLFLYDSQMQTYEGE-ILCLLDFYVHFSCQRQGVGQQILDYMFSQEHTEPYQLAL 143 Caenorhabditis ...
2_pfamImport  65 ILwEKVDSt---KSLLKGLLRVGYKTLYLTDND-QNQFMEkTMCILDFFIVPSEQRKGNGYNMFEAMLKAENVSVDQCAF 140
Q23192        72 IMwEKVNGs---KSILKGLLRVGYKTLYLTDNE-QNQYMEkAMCILDFFVVPTEQRSGNGFKMFDEMLKAENVTVDQCAF 147 Caenorhabditis ...
4HKF_A       153 DRPSPKFLSFLEKRYDLRNSVPQVNNFVVFAGFF 186 zebrafish
XP_002504713 148 DRPSPKLVAFMAKHHNLRAFAKQNNNFVVFDEYW 181
EFJ18369     151 DRPSQKLLSFLAKHYNLKRFYPQANQFVIYNAYF 184
XP_008183583 149 DKPSKKMLQFMQKHYSLKKLVDQGNNFVIFEEFF 182
XP_016663138 149 DKPTDKLLQFMWKHFQLSKLVNQENNFVIFEEFF 182
XP_003247218 150 DKPTTNLLQFMLKNFQLSKLVNQGNNFAIYEDFF 183
XP_016660281 150 DQPTNKLLQFLWKYFNLSKLVNQGNNFVIFEEFF 183
O45100       144 DNPSVTLLGFMSQKYGLIKPVWQNTNFVVFEELF 177 Caenorhabditis elegans
2_pfamImport 141 DKPSAALQQFFEKYYDRKEPVWQSNKYAVYPNFF 174
Q23192       148 DKPSAALQQFLEKYYDRKDLVWQSNKYALCSNFF 181 Caenorhabditis elegans
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