Conserved Protein Domain Family
NptA

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COG1283: NptA (this model, PSSM-Id:224202 is obsolete and has been replaced by 440894)
Na+/phosphate symporter [Inorganic ion transport and metabolism]
Statistics
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PSSM-Id: 224202
Aligned: 29 rows
Threshold Bit Score: 251.785
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
15639758  41 MHLVAVLLQGIGSLGFMLFGMKLMSDGIQKGTGESLHKILQVMTSNCFFAVLTGMAVTAIVQSSGATTVMTISFINAGVL 120 Treponema pallidum
15613916   1 -MTQQLFTLFAVFISLFLFGMAVMRAGLLTMNAEKARVGILRFVDNPLKGFFVGLLLTILLQSSSAVMIVTIGFVAAGYV 79  Bacillus halodurans
15613970   3 AELQTLLFMFFGGLGIFLFGIKYMGDGLQKVAGERLRDLLDKFTTNPLMGVLAGIVVTVLLQTSTGTTVLTIGLVNAGFM 82  Bacillus halodurans
1730991    1 MNRMLILISFTALILSFLAGMNMLRKGLISMAYSKIEERLLLFTDHPLKAFLISIVFTGILQSSSAFMVIVIGFVSAGVL 80  Bacillus subtilis
15791884     --------------------------------------------------------------------------------     Campylobacter jejuni
19703621   1 ---------------MFLYGMEHMSTSMQKIAGPKLKKILASLTNNRIFGILVGIIITALVQSSSVSTVMTIGFVNASLL 65  Fusobacterium nucle...
15925808   3 MSVTEVIFSFLGGLGIFLYGLKIMGDGLQASAGDRLRDILNKFTSNPVLGVIAGIVVTILIQSSSGTTVITIGLVTAGFM 82  Staphylococcus aure...
15900410   3 INWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDKYTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLL 82  Streptococcus pneum...
15675553   3 VNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDKYTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLL 82  Streptococcus pyoge...
16799897     --------------------------------------------------------------------------------     Listeria innocua
15639758 121 SLTQSIGVILGANIGTTVTAWIVALVgfqfkLASIAVPAFGIGYFLTFFK-HLHKGHLGESIMGFGLLFTGLGLLSSLIP 199 Treponema pallidum
15613916  80 TFRQSIGIILGTNVGTCFTVELIALD-----LHSLIVPLLLIGLIGLAIP-HLITYCLGCVSFGLACIFISMNGLENLAS 153 Bacillus halodurans
15613970  83 TLKQAIGVIMGANIGTTVTAFIIGIK-----ISEYALPIIAVGAALIFFIkNKKVNNIGQVIFGFGTLFYGLNTMGEGLN 157 Bacillus halodurans
1730991   81 SFKRTIPMILGTNVGSTFTTEFIAIK-----MDIVIWVLLIGGLLFFLTG-RYPLKQLGTSFLGLGIIFFCISGFSHLAG 154 Bacillus subtilis
15791884     --------------------------------------------------------------------------------     Campylobacter jejuni
19703621  66 TLKQALGVILGANIGTTITGWLLVLD-----IGKYGLPIVGLASILYMFMkKEKARTNLSAIIGVGLIFFGLQLMSQALS 140 Fusobacterium nucle...
15925808  83 TLKQAIGVIMGANIGTTVTAFIIGID-----LGEYAMPILALGAFLIFFFkRSKINNIGRILFGFGSLFFGLEFMGDAVK 157 Staphylococcus aure...
15900410  83 TLRQAIGIVMGANIGTTVTSFLIGFK-----LGNYALPMLFIGAVCLFFTkNRTVNNIGRILFGVGGIFFALNLMSGAMA 157 Streptococcus pneum...
15675553  83 NLRQAIGIVMGANIGTTITSFLIGFK-----LGDYALPMIFIGAACLFFTsNKKLNNFGRIIFGVGGIFFSLNLMGDAMD 157 Streptococcus pyoge...
16799897     --------------------------------------------------------------------------------     Listeria innocua
15639758 200 PLSVEELSFLKIAVEDRALSVFVGl--lSGFVLTVILHSSSATTAIVLTMAFGGVIGVEFAAASVLGSNVGSTIDAAIAA 277 Treponema pallidum
15613916 154 PLAAIPAIQAFIELTNDWLIVGAG----VGTLLTALIQSSTATTAIAMGFLNEEIIGIHGGIAIMLGANIGTCFTALLAS 229 Bacillus halodurans
15613970 158 PLRELQAFADLTVSMSENPLLGVL----IGTIFTAAVQSSSASIGLLQQLYDQGAMDLFAALPVLFGDNIGTTITAVLAA 233 Bacillus halodurans
1730991  155 PLTKLKTGADVLYHVNDSNWSALL----IGMVLTAIIHSSSVCIGILMSFMNEGIIGLTQAMSVVLGSNIGTCITAVMAA 230 Bacillus subtilis
15791884   1 -------------------------------MLTGVIQSSTVIMAIIVAALLAQQISLENSLAATLGTSVGGVVTAVLAS 49  Campylobacter jejuni
19703621 141 PLKDMSEFIDMFKMFEVDSYFGLLkvtaVGAIITALIQSSAATIGITIALATQGLIDYQAAVALVLGENVGTTITALLAS 220 Fusobacterium nucle...
15925808 158 PLASLDGFKQLMLDMSSNPILAVI----VGAGLTALVQSSSATIGILQEFYQQDLISLNAAIPVLLGDNIGTTITAILAS 233 Staphylococcus aure...
15900410 158 PLKDLQVFKDYMIELSKNPVLGVF----VGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVLFGDNIGTTITAIIAS 233 Streptococcus pneum...
15675553 158 PLKSVSAFQNYLATLGDKPFQGVF----IGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPILLGSNIGTCITAVLAA 233 Streptococcus pyoge...
16799897     --------------------------------------------------------------------------------     Listeria innocua
15639758 278 IGSKLNARRAAAVHVLFNVFGalvfLMFFHPVLALLCVLTPKNSGFDniTVRLALFHSMFNIVNTIIVFPFTKHLAAFVE 357 Treponema pallidum
15613916 230 IGSGRTSRLVAFAHLWLNVIG----VLLFIPLIPHLSHFVMTLTTIP--AIQLAHASTIFNVICSLAILPFVKPFASFIE 303 Bacillus halodurans
15613970 234 IGASVAAKRAALTHVIFNLIGtiivLIIIIPFTHFIAYLAEVFALNR--PMTIAFAHGIFNVSNTIIQFPFIGILAIIVT 311 Bacillus halodurans
1730991  231 VSGGYAAKQTAYAHVVFNVLG----VALVLPFLTAATGFVEQLSPDP--AQKIAHFSLLFNVVTALLFLPLTNLFYRLIH 304 Bacillus subtilis
15791884  50 LSTNIEGKKLAFANCIFNFGIafliVLIFPYFIHFLIFYPLR-------------------------------------- 91  Campylobacter jejuni
19703621 221 LGAKPNAKRAAYAHTLINLIGviwvTSIFRIYLHFLNHFVDPIN-HM--GAAIAAAHTIFNISNVILLIPFVGLLDKFLL 297 Fusobacterium nucle...
15925808 234 LAGSIAAKRAALVHVIFNLIGviifTIFLPVVIHLISLLQDVWHLKP--AMTIAVSHGIFNITNTLIQLPFVAGLAWIVT 311 Staphylococcus aure...
15900410 234 LGANIAAKRVAGAHVAFNVIGtvvcVIFLVPFTVLIHWFEATLNLAP--EMTIAFAHGTFNITNTIVQFPFIGALAYFVT 311 Streptococcus pneum...
15675553 234 IGSNIAAKRVAAAHVLFNLIGtiifMIILVPFTSLMLWLQSKLSLTP--EMTIAFSHGSFNITNTILLIPFISLLAMIVT 311 Streptococcus pyoge...
16799897   1 -------------------------MLILPLFTSLVAYMQGLFGLNP--EMTIAVAHGTFNVTNTFIQFWFIGAFAWLVT 53  Listeria innocua
15639758 358 WLIRPryDDAPERYQLVFQETAVKeSAEAHIFRAEIELKKMFSIAQGMLVTIRKSIQgtcmLsTDEIVTRLTKEEDYADQ 437 Treponema pallidum
15613916 304 TLHGPsq------------------------------------------------------------------------- 310 Bacillus halodurans
15613970 312 KLVPGd-DFYIEYKAKHLDPRFVGsSPAIALGQAKQEVLRMAEFSEKGLLEVSKYME----NgQKKHAEMAVQFEDAINN 386 Bacillus halodurans
1730991  305 LLIPAk-------------------------------------------------------------------------- 310 Bacillus subtilis
15791884     --------------------------------------------------------------------------------     Campylobacter jejuni
19703621 298 FVVKD--TGEDEVRVTKLASLKMT-LPSVIIEQTKIEVNSMVDIIEDAFLKLEESLKe--kDkIAKYNDSIIEAEDKLDL 372 Fusobacterium nucle...
15925808 312 KLVPGk-DIADDYKPQHLNKDLVYhAPGVALQETQKELQNVGQIVLSMFEDIREIT-----KdDKKLIKKLEQKHQAVET 385 Staphylococcus aure...
15900410 312 KIIPGe-DEVVKYEPLYLDEHFIKqAPSIALGNAKKELLHLGNYAAKAFDLSYKYII----DlDEKVAEKGHKTEEAINT 386 Streptococcus pneum...
15675553 312 RLIPGe-DEVVKYEALYLDRLLITqAPSIALGNAHKELVHLASYAIQAFEASYSYIM----TaDGKFGEKVKRYERAVDT 386 Streptococcus pyoge...
16799897  54 KLIPGd-DSRIDYKVKHLDTNLIDqSPGIALEMAREETLRMADYAKLGLQEAKEYLV----NqEPKHAESTVQVEEAVNN 128 Listeria innocua
15639758 438 MQEQLSRFLIKTSHLSLSEKAKHNVQLMFSIADDIENITDHLCGIGLYFHKSIKGNVPLKRDDIEELVPYVGMVDECVDF 517 Treponema pallidum
15613916     --------------------------------------------------------------------------------     Bacillus halodurans
15613970 387 LDRKITEYLISISSRSLSAQDSKMHGMLMDTVRDIERIGDHIENIVELKDYQKANKVKISEKALHDLQEMFDLTHSTLTE 466 Bacillus halodurans
1730991      --------------------------------------------------------------------------------     Bacillus subtilis
15791884     --------------------------------------------------------------------------------     Campylobacter jejuni
19703621 373 YEKEIYDSNFSLLSKSLSKELIEDTRMNLLACDEYETIGDYQNRIANRLFMLYENSIDLDEVRAKMAFKLHSLAVELFND 452 Fusobacterium nucle...
15925808 386 INDSIRNYLVRISTKAITKADVERLAVMFDVNRSILKVAELTEEYVAQLKRQHDEDIRITEDAQRGMDKLFNHVAESFDK 465 Staphylococcus aure...
15900410 387 IDEQLTRYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAALKELEEVYRQTSDFIKD 466 Streptococcus pneum...
15675553 387 IDEELTTYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISARQELTEMYQLTHCLTLD 466 Streptococcus pyoge...
16799897 129 LDRKITEYLTKISSVALTNNETEEHALMLDTVRDIERVGDHMENIVENIDQLIKNKAKMSEEASTQLIEMFELTTSNFER 208 Listeria innocua
15639758 518 VYSHLNRPLEDKQVLHVNQMTHSIESKGAHLKGLVRRRLEQGADVKAELLYMDIVRGIEAVGNYALSISRWLARML 593 Treponema pallidum
15613916     ----------------------------------------------------------------------------     Bacillus halodurans
15613970 467 AIMSLETGDLEAARSVIEKEEHIDQMERKLRKQHIIRVNEGNCTGAAGIVFVDIVSNLERIGDHSVNIAEAVIGEN 542 Bacillus halodurans
1730991      ----------------------------------------------------------------------------     Bacillus subtilis
15791884     ----------------------------------------------------------------------------     Campylobacter jejuni
19703621 453 ISRAVRTNEKELYPIGMKKYQALKTYYKEVKREHFSRAENIPARLNTG--YLDIINYYKRIADHIYNIIEYVMKI- 525 Fusobacterium nucleatum...
15925808 466 AIDMLDVYDKTKKDEIVERSRESFNIEHKLRKGHIKRLNRGECTTKGGLLYIDMIGVLERIGYHSRNVSEALVGLN 541 Staphylococcus aureus s...
15900410 467 ALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGECSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQ 542 Streptococcus pneumonia...
15675553 467 AIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGECTAQAGINFIDIISHYTRITDHALNLAEKVLSHQ 542 Streptococcus pyogenes ...
16799897 209 AVKAMHKKDRALAEETILVEKDIDKAERRLRKSHIRRLNEGKCQVVSGILYIDIVSDLERIGDHANNIAESVLELN 284 Listeria innocua
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