Conserved Protein Domain Family
PAP2_wunen
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cd03384: PAP2_wunen 
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.
Links
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Statistics
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PSSM-Id: 239479
Aligned: 29 rows
Threshold Bit Score: 141.999
Created: 29-Dec-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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active site
Feature 1:active site [active site]
Evidence:
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                            #      #                                                 
NP_524991 191 ECYHRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFytlCQPvmkdgttcsdpinaaryieeftcaavditskqlkdmRLSF 270 fruit fly
BAA91072  123 RIIRFTGVFAFGLFATDIFVNAGQVVTGHLTPYFltvCKPnytsadcqahhqfin------ngnictgdleviekaRRSF 196 human
AAH71430  122 RIIRFIGVFAFGLFATDIFVNAGQVVTGNLAPYFlnvCKPnytgldchfshqfia------ngnictgnqvvveraRRSF 195 zebrafish
AAH74287  107 RTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFltvCKPnytalgcrqftqfit------danactgipdlvikaRRTF 180 African clawed frog
XP_422320 102 RTIRFLGIYAFGLFATDIFVNAGQVVTGNLAPHFlalCKPnytalgckqytqfis------sahactgnpdlimkaRKTF 175 chicken
XP_795941 129 RMFRFTGVFACGAFATWIITDAAQRVTGIQTPYFltvCRPnytaldcntfitdy---------ecvkrdddlleqaRLSF 199 purple urchin
XP_790637  18 RTVRFTGIFLLGAFITWILTRAGQLILSHPAPDFftrSTCtpcsngadgtft-------------isdcttiidsaRQSF 84  purple urchin
AAO85400  126 RAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFltvCKPnytslnvsckensyiv-----edicsgsdltvinsgRKSF 200 human
XP_422319 102 RAVRFVGVHVFGLCSTALVTDIIQLSTGYQAPYFltvCKPnytslnvscsensyvv-----edicsgadaniinagRKSF 176 chicken
XP_688370 100 RAVRFVGVHVFGLCITALITDIIQLATGYHAPYFltvCKPnyttlniscdensfiv-----ddicsgpdpaainsgRKSF 174 zebrafish

Feature 1      ###                                             #     #   #                
NP_524991 271 PSGHASFACYSMLYLVIYLhrrmqwkqlrmlcHLLQFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVVVT 346 fruit fly
BAA91072  197 PSKHAALSIYSALYATMYItstiktkssrlakPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLG 272 human
AAH71430  196 PSKDASLSVYSAVYVTMYItstiktkssrlakPVLCLGLLCAAFLTGLNRVSEYRNHCSDVVAGFILGSSIALFLG 271 zebrafish
AAH74287  181 PSKDAALSVYAALYLAMYItstikakgtrlakPVLCLGLMCLAFLTGINRVAEYRNHWSDVIAGFLIGISIAVFLV 256 African clawed frog
XP_422320 176 PSKEAALSIYAAMYLAMYItstvkargtrlakPVLCLGLMCLAFLTGINRVAEYRNHWSDVIAGFIIGISIAVFLV 251 chicken
XP_795941 200 PSLHASLGSYAAVFTMAYMtsqvsipctrlpiPLASLGLLSGGLLWGITRASKYRHHWSDVAVGFLLGMVVALYLV 275 purple urchin
XP_790637  85 PSLYASLSAYASVYVAVYItmlmklnaahtlrPFAGLCFIAVPYLLGVQQIAAHRAHWGDVIGGWILGSVVAFYLI 160 purple urchin
AAO85400  201 PSQHATLAAFAAVYVSMYFnstltd-sskllkPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLG 275 human
XP_422319 177 PSQHATLAAFAAVYISMYFnstltd-sskllkPLLVFAFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLV 251 chicken
XP_688370 175 PSQHATLAAFAAVYISMYFnatltd-sskllkPLLVFSFIICGIICGLTRIIQFKNHAVDVYCGFLLGGGIAIYLG 249 zebrafish

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