4BIT


Conserved Protein Domain Family
Armet
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pfam10208: Armet (this model, PSSM-Id:402006 is obsolete and has been replaced by 462997)
Degradation arginine-rich protein for mis-folding
This is a family of small proteins of approximately 170 residues which contain four di-sulfide bridges that are highly conserved from nematodes to humans. Armet is a soluble protein resident in the endoplasmic reticulum and induced by ER stress. It appears to be involved with dealing with mis-folded proteins in the ER, thus in quality control of ER stress.
Links
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Statistics
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PSSM-Id: 402006
Aligned: 31 rows
Threshold Bit Score: 179.382
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4BIT_A        10 DCEVCKEFLNRFYKSLIDRGvnfSLDTIEKELISFCLDTKGKENRLCYYLGATKDAATKILSEVTRPMSVHMPAMKICEK 89 
XP_006007876  26 ECQVCIGFLDRFYQSLKAKNadfAPVNIEIELFDFCRAATGKESRLCYYLGATSDAATKITSEVTRPMSSHVPVNKICEK 105 coelacanth
XP_007630074  36 DCEVCKAFLNRFYNSLLTRGvdfSVDTIEEELASFCLDAKGKESHLCYYLGASKDSATKILGEVTRPLSVHVPIVKICER 115 Chinese hamster
XP_017829560  36 DCEVCQEFLNRFYKSLIDRGvdfSLDTIEKELISFCLVTKGKENRLCYYLGATKDAATKILSEVTRPMSVHMPAMKICEK 115 white-tufted-ea...
XP_004049123  36 DCEVCKEFLNRFYKSLMDRGvnfSLDTIEKELISFCLDTRGKENRLCYYLGATKDAATKILSEVTRPMSVHMPAMKICEK 115 western lowland...
XP_001368942  38 DCEVCKEFLERFYRSLIAKGvdfSQEIIENELISICLDAKGKENRLCYYLGATNDAATKILSEVTRPMSAHVPAVKICEK 117 gray short-tail...
XP_001515575  21 lakVCREFLDRLYNSLLSKDihfSGDVKEKELTDMCLVAKGKENHLCYYLGATSDAATKILSEVTHSMNAHIPAVKICEK 100 platypus
XP_003228037  38 QCEVCQGFLENVYNSLKEKHsdfSLASIENELIRCCLNTKGKENRLCYYLGATSDAATKIISEVSRPMSAHVPVTKICEK 117 green anole
NP_001116753  27 ECEVCVGFLGRLYNSLVIRHtelSPELVEEGLIRACAETTGKENRLCYYLGASSDSAAKVTGEVIRPLSAHVPVHKICQR 106 zebrafish
XP_007252426  24 ECEVCVRFLERLYKSLVATHrelSSAFVEEELRKACAEATGKENRLCYYLGASSDAAAKVTGEVSRPLSAHVPVQKICQR 103 Mexican tetra

4BIT_A        90 LKKLDSQICELKYEKTL-DLASVDLRKMRVAELKQILHSWGEECRACAEKTDYVNLIQELAPKYAA 154
XP_006007876 106 LKKKDIQICELKYDKQL-DLNSVNLSKLKVAELRKILDGWGAVCRACIEKTDFVELIKELAQKHAS 170 coelacanth
XP_007630074 116 LKKMNSQICKLNYEKKL-DLASVDLWKMRDAELKQILHSWGEECRACAEKNDYVNLIKELAPKYVE 180 Chinese hamster
XP_017829560 116 LKKLDSQICELKYEKKL-DLASVDLRKMRVAELKQILHSWGEECRACAEKTDYVNMIQELAPKYAA 180 white-tufted-ear marmoset
XP_004049123 116 LKKLDSQICELKYEKTL-DLASVDLRKMRVAELKQILHSWGEECRACAEKTDYVNLIQELAPKYAA 180 western lowland gorilla
XP_001368942 118 LKKIDNQICELKYEKKL-DLESVDLSKMRVAELKKILSSWGEECKACIEKTDLVDLIKKLAPKYTS 182 gray short-tailed opossum
XP_001515575 101 LKRIDSQIREFKYERKL-DLESVNLLRMRVAELKRILDSWGEACTACVEKADFVNVIKELTPKYAA 165 platypus
XP_003228037 118 LKKTDIQICELKYERKL-DLTSVDLSKMRVAELKKILDGWGEVCRACIEKTDFVDLIKELAPKHAA 182 green anole
NP_001116753 107 LQRRDGQICELRYERLVlDWSTDALSKMRALELKRVLASWGEECRACLEKSEFIALIQEVAPKHSA 172 zebrafish
XP_007252426 104 LQHRDQQICELRYEQQVlDWSREALSKMRVLELKRVLASWGEECRACLEKSDLIDLIQEVAPKHNT 169 Mexican tetra
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