EDO36968      23 KYINGCFSCLKFPACCQQVLIVL--DKYYASYQPCTLQNPalfvmSFLEELIEKYLYHTTDKTGQ--------------- 85  starlet sea ane...
EFX85120       9 PDLHRILRRLDFPQSAKEALACLgmEKQLCLPLAHTRPPTsk-qlDYIGEIIDEFVFCEIDHKGArr------------- 74  common water flea
XP_002408288   2 TDVRVSLRKIEFPTVIFEALRQM--QKLLSNEGRSPTYA------HVAKEIAEEFIFQDFDQRRQpphhhhhhhpsqqpp 73  black-legged tick
XP_002613624   2 pSLRDSLAYEGFPQATRRVLEHV--EASCSGGEAG----------TNLGALVEEFVHFRPPDALPhh------------- 56  Florida lancelet
XP_011405071  23 SEIDQTLKTLQKPAACNFILSMV--ERYIRSLSSPDLVVSslpnkEKLLSLIDSYILLVPTAAASssv------------ 88  Amphimedon quee...
XP_015215558   2 SDIRHSLLRRDALSAAKEVLYHL--DIYFSSQLQSTAVPIv---dKGTLELVEEFIFHVPKERGVlp------------- 63  spotted gar
XP_014353234   3 SDIRHSLLRRDALSAAKEVLYHL--DIYFSSQLQKVPLPIv---dKGTIELVEEFVFQVPKERAAqp------------- 64  coelacanth
OCA22413       2 SDIRHSLLRRDTLSAAKEVLYHL--DIYFSSQLQNAPVPLv---eKGPIELLEEFIFQVPKDRGSht------------- 63  tropical clawed...
XP_414955      2 SDIRHSLLRRDALSAAKEVLYHL--DIYFSSQLQSAPLPLv---dKGPAELLEEFLFQVPKERGApp------------- 63  chicken
Q7ZTY6         2 SDIRHALLRRDPLSAAKEVLYHL--DISLGSALQSSAGPPag-leKSTVELVEEFIFHVSKDRNIqs------------- 65  zebrafish

EDO36968      86 -----GLSAILELRLLEVMCSHFQTQE-SDFVRYCVFDLLFGVSRDDlree--------------------kfeCRIDLL 139 starlet sea ane...
EFX85120      75 ----kRLNPLQELQLLEVLLGYFAAGE-DKVILNTVFMMLFTPPHTPspspspspsgfaradvftpgtataalsDRMRIL 149 common water flea
XP_002408288  74 qlrrrKMSAIRELQIIEIMASSFQSSR--PDMCQKVFFILFPSADPAvm------------------------dTRVPIL 127 black-legged tick
XP_002613624  57 ----tGLNALQELQLLQILSDYFGAKT-NVGLARQVFMVLFGTRGGAdrl----------------------tdHKVKLL 109 Florida lancelet
XP_011405071  89 ---ewPFNVFEELELLEALRGQVEERQlSKEIQLALFDTLFGLADDDeva----------------------saHRLSLL 143 Amphimedon quee...
XP_015215558  64 ----kRMSSLQELQLLEIMCSYFQEQS-KDAVRQVIFSALFSPQGNKad------------------------dSRMAML 114 spotted gar
XP_014353234  65 ----kRLNSLQELQLLEIMCNYFQEQS-KDSVRQIIFSALFSPQGNKad------------------------dNRMIIL 115 coelacanth
OCA22413      64 ----kRFSAMQELQLLEILCNYFQEQN-KEAVRQVIFSSLFSPQGNKad------------------------dQRMALL 114 tropical clawed...
XP_414955     64 ----kRLNSLQELQLLEIMCNYFQEQT-KDSVRQIIFSSLFSPQGNKad------------------------dNRMALL 114 chicken
Q7ZTY6        66 ----kRMSCVQELQLLEIICSYFQEQS-KDAIRQVIFSALFSLQGNKad------------------------eSRMAML 116 zebrafish

EDO36968     140 TKLVSMAVA-LQSGNVLDCMAWWIQKHRHAPDFVVKIASSIVDDYTCL-VP-----ASLPFLESVSFISPPLACQLIITQ 212 starlet sea ane...
EFX85120     150 ARLVSAAVA-SRNLAVLNCTGVWMQQLGCLSQHSLNLSRVFIEDYFVLnTPqsnisSSTSYLEQLPQQAPHFTSCFLTAA 228 common water flea
XP_002408288 128 SRLVSLSIA-LKSHNALNCVGFWMHVCGCTSEPSLHIVRHVIGDYLSL-IP-----SSAEMLKDLADISPLFCASLATSL 200 black-legged tick
XP_002613624 110 GKLVSMCIA-TQHEMVLDCTAYWILQEGASSSPVLTLLTSIIQDYCML-MP-----GTLDTLQRVDKTSPSFACQFVTIV 182 Florida lancelet
XP_011405071 144 KKLVSLSISgLGNGTVLHCTTYWMEL---YPIAAAELATNIYSEFCEL-LP-----NAMEPLLALGNNCPSFTKLLILHL 214 Amphimedon quee...
XP_015215558 115 GKLVSMAVA-VCRVPILECAALWLQR--THAIYCVRLAKVLVDDYCSL-VP-----GSVQTLQQIFSASPRFCCQFITAV 185 spotted gar
XP_014353234 116 GKLVSMAIA-VCRVPVLECCALWLQR--TPAVYCVRLSRILVDDYCSL-VP-----GSGQTLKQIFHASPRFCCQFITAV 186 coelacanth
OCA22413     115 GKLTSMSVA-VCRVPVLECAASWLQR--TPAVYCVRLAKALVDDYCGL-VP-----GSVQTLKQIISVSPRFCCQFITAV 185 tropical clawed...
XP_414955    115 GKLVSMAVA-VCRVPVLECAAFWLQR--TPAVFCVRLAQALVDDYCNL-VP-----GSIQTLKQIFSASPRFCCQFITAV 185 chicken
Q7ZTY6       117 GKLVSMSIA-VCRVPILECAAIWLQR--THSAWCVRLAQVLMEDYCTL-VP-----CAISTLQNICSASPRFCCQLITAV 187 zebrafish

EDO36968     213 TSVYTMKPQPDRDeteaqPSNTLVKVIVKWISTNLGICLAKPNNTflsLPSlhnppmsePAATPL--PTCPVLGLLTWTV 290 starlet sea ane...
EFX85120     229 AELYGGIDGNRSAyi--pPPMCLLNTIVNWVSSNPRLCLTPLTLNl-qPLL--------PKGSIVmtSVTPLAGLLKWCV 297 common water flea
XP_002408288 201 THMTPTN-----------PSVEIVDLLASWVRAQPLLCFTPMEAI--------------PPQLYSqcLQTFLPGLVAWCV 255 black-legged tick
XP_002613624 183 TSLYQLKPDAASSs---hPPPSLLEVIAEWVAGNPRICLASLKDT---------------KGTVP---VTPIPGLCHWCV 241 Florida lancelet
XP_011405071 215 TSSFPISSSSSIGha-scPPLRCIHLLSQWILTNP-DSLTTFPDTrdsPILirsqrvkrPINAP------PLMGVAQWVI 286 Amphimedon quee...
XP_015215558 186 TALFDMSSDDLI------PPNDLLEMVVTWIFDDPRLTLITFLNTpisANL--------PVGCLD---LTPLVGLVRWCV 248 spotted gar
XP_014353234 187 TVLYDLSTDDLI------PPYDLLEMVTSWILEDPRLTLITFLNTpiaANL--------QISYLE---LTPLTGLIRWCV 249 coelacanth
OCA22413     186 AALYDMSSEELL------PPHNLLEMIVSWIFDDPMLILITFLNTpitANV--------PLGFLD---FSPLMGLVRWCV 248 tropical clawed...
XP_414955    186 TALYDLSSDDLI------PPSDLLELIVSWIFEDPRLILITFLNTpiaANL--------PIGFLE---LTPLTGLIRWCV 248 chicken
Q7ZTY6       188 TALYDFSTDELT------PPPALLEMLVGWITEDPRLLLLTFINSplnSSL--------PLGCLE---ITPLLGLLRWCV 250 zebrafish

EDO36968     291 LQPLV----------------------CLVDQEESTRDLYSELQLGILQTLvrsgrnkmnpkdememepgEVMDESDLLR 348 starlet sea ane...
EFX85120     298 EAPFNpslkkts--------pvklektKDTKSTWNENSYYSQLHSSLLESMqer--------------svLQNQQQLLQA 355 common water flea
XP_002408288 256 LAPIG-----------------------SVDSTDPQAELYSYLHYALLEMLir---------------agQVTPRAPIVF 297 black-legged tick
XP_002613624 242 KSPLV----------------------RNPESTQEEAMIYSKLHLGILQSL-------------------LTAQNVAPNA 280 Florida lancelet
XP_011405071 287 LEPLIpdqwivrnt-----errlrgrdEEKQLVTEYRSSMSQLHANLLTYL--------------------MSLSSSPVH 341 Amphimedon quee...
XP_015215558 249 KAPLAykrnrkpaltn-ghisklskeeKEEEGVGDRDLLYSKLHLSILQVLmml-------------qvhLTEKNLFGRL 314 spotted gar
XP_014353234 250 KAPLAykrnrktsltn-ghnaktskdlGTAM-EKDCNTLYSKLHLSVLQVFmml-------------qvhLTEKNLYGRI 314 coelacanth
OCA22413     249 TAPLAyrrk---------------qkaAGGQLPVESQGLYSKLHLSMLQGLmvl-------------qthLTEKNLYGRL 300 tropical clawed...
XP_414955    249 KAPLAykrkkkaslsnghptskiakdsTEGD-DGDCHQLYSKLHLSVLQVLmml-------------qghLTEKNLYGRL 314 chicken
Q7ZTY6       251 KAPLAyhrgrks---------amtnghGDGEKGTAYEELYSKLHLSVLQVFlml-------------qvhLTEKNMFCRL 308 zebrafish

EDO36968     349 HLLKGEELHSLTSTVTSFIDNLKHnaiakGAVQEKIDLALDRLAQVLQVAIATGCLSCTRDELLAICKSLPA 420 starlet sea anemone
EFX85120     356 EVISPRHLVALVRGLLDSCAKNN-------SSNEKIQLSLDRLAQSVQVAQSSGCLYGNTHELMQALRTLPY 420 common water flea
XP_002408288 298 PFLPSHYVVQVAETLKRASS----------PNSKGWDLALNRLAQVLQAAFASKCVHGNLEPMFQTLRQLPS 359 black-legged tick
XP_002613624 281 KLLPVSAVEEIVSDLRALVQTSE-------GQGEATQLAVERLAQVMQVAMATGSTQLNRKQVAGLYGQLPE 345 Florida lancelet
XP_011405071 342 IAMTSTSLSSLVGRLLEFQQKTATl---lQEEKNKTELSLERLSQFLQIGLDVGIVSLNPDFLTTLLSTLPK 410 Amphimedon queenslandica
XP_015215558 315 GLLVFDHMVQLVEELSRLVDELNP-----LNATKETELSLDRLAQALQVAVASGALLCTREDLRSLCSRLPH 381 spotted gar
XP_014353234 315 GLILFDHVVPIVEEFSRLADELNP-----VHAMKEIELSLDRLAQALQVAMASGALLCTRDDLRSVCSRLPH 381 coelacanth
OCA22413     301 GLFHFDQLVPLVEELGQLCDELNP-----LNAEQEMELALDRLAQALQVSMATGALLCARDDLRTLCARLPH 367 tropical clawed frog
XP_414955    315 GLIPFDHVVPLVEEINRLSDELNP-----LNASKEIELALDRLAQALQVAMASGALLCTRDDLRTVCSRLPH 381 chicken
Q7ZTY6       309 TVLPVESVAALIEEVGRLCEKLAP-----LLDASHIQLALDRLAQALQVAMATGALLCAREDLRALCSRLPH 375 zebrafish