XP_011613892 21 QEMQFWLDKAVAWGQAQTVETQRDTCQHLSRLRDFTQQLLKHINSMASTTeTMKRLPLIGQFLGRLCWIPSVTADASSRS 100 torafugu Q00597 10 CDYQFWMQKLSVWDQASTLETQQDTCLHVAQFQEFLRKMYEALKEMDSNT-VIERFPTIGQLLAKACWNPFILAYDESQK 88 human XP_007497985 10 LNFEFWLNKAVAWGQTTTLESQQDVCLHLPQLQKFLQQIYETLKHMDFSM-AIDRFPLIGQLLGRLCWNPFVIGYDENQK 88 gray short-tail... XP_008101427 10 LSFEFWLHKTLKWGQSTTSESQQDVCLHLPELQEFLLQIYGALKHMNCRT-AVQQFPLVGQLLGRLCWNPLVIGYDECQK 88 green anole XP_002194329 10 LNFEYWLDKAVEWGQATTLESQKDVCLHLPQLQEFLHQLYEAIKHLGPTV-VIQQFPLIGQLLGRLCWNPFVIGYDESQE 88 zebra finch XP_015135800 10 LNFKFWLDKAIEWGQATTLESQKDVCLHLPQLQEFLHQTYETLKHMNSIA-AIQQFPLIGQLLGRLCWNPFVVGYDESQK 88 chicken XP_023199100 17 QQMPFWLEKAIAWGHTDTTHTRNDISLHLKRLRDFLQQLLSEISSVSSTTeTLNRLPLLGQLLGQLCWNPHVTAEGASRG 96 southern platyfish XP_005452188 21 QEMQFWLDKAVAWGQADSPDTQKDTCLHMSRLRDFLQQLLTQVNSMSSTTeTMKRLPFLGQLLGRLCWNPYVTVCDTSRG 100 Nile tilapia XP_022526809 7 LQVTFWMDKAVTWGQATSLSARLDTTKHLNSLRSFLQQLLEKLQSMSSTAeAMKNLPFVGQFLGRLCWNPYVTADGESSR 86 Mexican tetra XP_005167236 7 TNVQFWMNKAVNWGEASSCSALLDTSRHLGPLRNFLQQILQGLQQMNSTSeAMKTFPFVGQFLGRLCWNSCVTADERSQK 86 zebrafish
XP_011613892 101 LLLQCLWGLFSEHPGSAVERKANQWIRTVLCQLVTe-----EdaKVEPLIRQMGVAPKDYHLGVLRKRLALLQQNFEKNC 175 torafugu Q00597 89 ILIWCLCCLINKEPQNSGQSKLNSWIQGVLSHILSalr-fdK--EVALFTQGLGYAPIDYYPGLLKNMVLSLASELRENH 165 human XP_007497985 89 ILMWCLCCLYCSEPQNSIEVEANIWIRSLLCHLLSssklglN--EVGSVIQALGYTSPDYYPELLKNMVLSLVTELRVNH 166 gray short-tail... XP_008101427 89 ILMWCLCCLYSGEPQSPVELKANSWIQSSLCHLLSisglgsHntDLNSFISTLGFTSADYNSKLLENVVLSLVTELR-NQ 167 green anole XP_002194329 89 TLMWCLCCLYSSEPQNAVELKANSWVRSLLCHLLSsskwesNeaETSAFISALGYTSADYYCHLVKNMVVSLVRELRENQ 168 zebra finch XP_015135800 89 TLMWCLCCLYSSEPQNPVELKANSWIRSLLCHLLSsskwerIeaETSTFISALGYTSADYYCHLVENIVSSLVTELRENQ 168 chicken XP_023199100 97 LLLQCLLALYSEHPSNAVERKANQWIQKVLCHLATd----eEdgAAVGLMKHLGVPTKEYHLKVLKKMVTRIQESIGNSR 172 southern platyfish XP_005452188 101 LLLGCLWELYSERPSNAVEQKANQWIRKVLCQLSTe----eDdtAAQALMKCTGVPAKEYHLKVLRKKVALLQENVGQSC 176 Nile tilapia XP_022526809 87 LLLQCVWHLYSVNPQNAVERRANEWIQNLLYHLTSe----eEgsVGHALEKHSGSLNQHYYSETLKKMVALLTEEVSMNC 162 Mexican tetra XP_005167236 87 LLLRCLSCLYSAEPLNAVERKANMWIKNMLCHLISe----eEgsVAHATVKHAGSTPMRYHTEALQKVVSLMVEEVSKSC 162 zebrafish
XP_011613892 176 NCLADKNQRCPHDDSLAVSESCIPLVTCQEAAPLINTLLQRPASCISAALSEDFLDALNSAHSRQSLLLEEQGIISLWYH 255 torafugu Q00597 166 LNGFNTQRRMAPERVASLSRVCVPLITLTDVDPLVEALLICHGREPQEILQPEFFEAVNEAILLKKISLPMSAVVCLWLR 245 human XP_007497985 167 LNGFSIQKIIPERQIKAISLLCVPLLTLPDILPLLEALLTYHGGEPKEILSSEFLEGVNEAFLQKKIVLSESAVFSLWLR 246 gray short-tail... XP_008101427 168 FNQFKSQQSIS-SRITSISLLCMPLITLPDVIPLVEALLSYHDGGSQEVLHSTFLEAVNKALLQKKISLSESAVVQLWLR 246 green anole XP_002194329 169 FSGLNIQESISASRVNAISIVCVPLITLPDLAPLLETLLLYHGGSSKEILSSEFLESVNEAFLKKKISLPESVIFSLWLR 248 zebra finch XP_015135800 169 FNELNIQERISVSRVNAVSLFCLPLITLPDLTPLLETLLLYHGGASKEILSSEFLEAVNDAVLKKKISLSESAIFSLWHR 248 chicken XP_023199100 173 CSVSSTNKGCSCGSIWAASEACVPLITCPEASPLIGALLQQQMTCIREGLSENFLDALHSAYLRCDLLLDEQAVVSLWYQ 252 southern platyfish XP_005452188 177 --TLFNSQRCSCDRIVAISEACIPIVACPEASSLISLLLQRPVACVTEVLSEDFLDALTSAYSRQGLALEEQALVSLWYH 254 Nile tilapia XP_022526809 163 ISSTPFTERCSCNRLRAVSVACVPLVTCPLVAPLTGALLKHQVSCGCSHLSEEFIEAVSTAWLSKKLVIEDLAVIALWCH 242 Mexican tetra XP_005167236 163 DCLPNASARCSNSNIHTMSTACIALVTCTQMAPLIGALLKHSESCGSSCLNQEFINEVGEAFISKRLVLEDEAVISLWCQ 242 zebrafish
XP_011613892 256 NLPSLEEAVLRLLESVLANNESSPQKLEQLLEQALLPKaCAQHCSMFLVVNDIFRSFLKQAERAESVHCLIHTFTRCFLR 335 torafugu Q00597 246 HLPSLEKAMLHLFEKLISSERNCLRRIECFIKDSSLPQ-AACHPAIFRVVDEMFRCALLETDGALEIIATIQVFTQCFVE 324 human XP_007497985 247 HLPSLEKATLHLFEKLTSRYINIPEELEGVIKDSLLPQ-AACHPSIFRIVDEIFRNALLETNGTSEVLTIIQVFTQCFVQ 325 gray short-tail... XP_008101427 247 HLPSLEKAVLQTLGNLISSQPCSVQEMACLIKDSLLDR-AACHPAIFRTADEILKNALLETDGAPEVMTVMQVFTQCFVQ 325 green anole XP_002194329 249 HLPSLEKATLHLLDQLFSIQLNSLEEVACVIKDSLLPQ-AASHPAIFRIVNEIFKNALVETGGTSEVLTIIQVFTQLFLQ 327 zebra finch XP_015135800 249 HLPSLESATLSLLDQLTSLQINSLEKVACVIKDSLLPQ-AASHPAIFRIVNEIFKNALLETDGAPEVMTIIQVFIQLFIQ 327 chicken XP_023199100 253 SLPSLEEAVLNLLESATTA-GSTPSKVEEQVPKSLLPKaCAQHCSVFLVVNDIFRTVLKQNERNERVKNVFQTFTKCFFM 331 southern platyfish XP_005452188 255 SFSSLEEAVLSLLQSVITT-GLTPQKLEQQVAQSLLPKaCAQHCSVFLVVNDIFRSVLKQAEVNEFVKALVQTFTKCFLK 333 Nile tilapia XP_022526809 243 SLSSLERAVLSLLESVLSDQGSVMQSLEKTVTDSLLPKaSALHCHLSLLVNDVFRNVLMTMEENLAVRSLIQVFTACFLQ 322 Mexican tetra XP_005167236 243 SALSLEGAAVSLLESVLSDHQLTTQSLDKHVNDSLLPQaSARHCHIFLTVSEIYRNVLTEIDENLAIRTLIQVFTVCFLQ 322 zebrafish
XP_011613892 336 ELALVPHQNSVPLKALFPQSPQSLLMPLLTLPSEMHQEAWRHHLKWLSDSLRRLTEEEEeddrdg---srsscLKSHHRV 412 torafugu Q00597 325 ALEKASKQLRFALKTYFPYTSPSLAMVLLQDPQDIPRGHWLQTLKHISELLREAVEDQT--------------HGSCGGP 390 human XP_007497985 326 AFQKDSKQLKFPLKSYFPYASPSLVMILLQDPEDLPRGLWCQHLNHISKTLKNIVEDQS--------------TQSCGSP 391 gray short-tail... XP_008101427 326 AYHENNKQHKFPLKAYFPQNPHLLVMVLFKDPADLSAKGLHQHLNHIAEILKTTVETKG--------------VRSCGNL 391 green anole XP_002194329 328 ERQNENKQHKFPLKAYFPYHHQPLVRGLVRRPFELPTTYWSQHVKRISDMLKALVEDTN--------------ASSLTDL 393 zebra finch XP_015135800 328 VQQNENKQHKFPLKAYFPHHHQPLVIALLRRPFELPSTHWLQHLKHISDTLKSIVEDTN--------------VSSFADL 393 chicken XP_023199100 332 ELSRLQPQTSASLKAFFPQSPPSLLIPLFTMPSEMPQESLKNHLIWVSSSLQRLTEEEEdeeds-----dssnIRGNHKV 406 southern platyfish XP_005452188 334 ELALLKPQTSISVKAFFPQSPSSLLVPLLTMPSEMPQGAWRNHLNWLSSSLQRLTEEEEegdg------dgrsTRGHHNV 407 Nile tilapia XP_022526809 323 IRTDQNPEERPPLKAFFPHVPQSLLTPLLTTPSEVPKQAWLQHLCWIRELVQEILCERNgeeegkekeeeeksRRQRRAV 402 Mexican tetra XP_005167236 323 RLTGQNSQDRLPLRAFFPNVMPSLLSPLLTAPSEVPREAWLDHLSWITSLLQSVTENEEe------------dVRAYQPM 390 zebrafish
XP_011613892 413 FEAWFLLVQCVHWVQLTAQLLVTSETQDCGPLLWLFTFYYHPTNRGHHRASQLGHAKEALDHLRALFspLNPPLPVGSLQ 492 torafugu Q00597 391 FESWFLFIHFGGWAEMVAEQLLMSAAEPPTALLWLLAFYYGPRDGRQQRAQTMVQVKAVLGHLLAMS--RSSSLSAQDLQ 468 human XP_007497985 392 FEQWFLFIHFGEWADIAAEELLMWRAESPEALLWLLAFYYNPHDQNQEWIQTMVDVRAVHGHIMKLF--DRTPLSVKDLQ 469 gray short-tail... XP_008101427 392 FENWLLLVHFGEWVDIAAEQLVVSQCESSGALLWLLVFYYEPSDENQRRTQTMREAKSVCDHLTTLS--RASTISVPELE 469 green anole XP_002194329 394 FEIWFLVACFGEWLDIAAEQLVKAAVE-PDPVLWLLAFYYCPKNENQQRAQTMVEAQEVYSHLMMLF--NCADLSLKDLE 470 zebra finch XP_015135800 394 YEIWFLVACFGEWLDIAAEQLMKAAVA-PDALLWLLAFYYCPQNENQQRTQTMVESQAVYSRLMMLY--NRTVLSFGDLQ 470 chicken XP_023199100 407 FEAWFLLVQCGYWVQVVVQLLVTSGPEDCGPLLWLLTFYHHPTNRWHHRASQLVQAKAAWDHLYSLFsiEAHLLPADHLQ 486 southern platyfish XP_005452188 408 FEAWFLLVQCAHWVQVAVQLLVTSGTEDGDPFLWLLIFYHYPTNRWHHRASQLARAKEAWNHIRTLFsgAAHPLPSDRLQ 487 Nile tilapia XP_022526809 403 FETWFLLVQCGHWVDAAAELLVSVGSEESEPLLFLLTFYHHPTNRGHQNTQQTMVAREAWSHLRILF--LTHTPPPEKLS 480 Mexican tetra XP_005167236 391 FEAWFLLVRCGYWVDTAVELLVLAASGNTEALLWLLTFFHHPTNRGHQRSQQTAVAREAWTHLRMLF--LNHPPPPRHLS 468 zebrafish
XP_011613892 493 SVMTLLSPaqQQQQQSLsTLLIINLLVNFAVFSRQSLIGSAEVLQMVVDQSGLLNEAARVLVSLELSLNRGRHLSSdtnR 572 torafugu Q00597 469 TVAGQGTD--TDLRAPA-QQLIRHLLLNFLLWAPGGHTIAWDVITLMAHTAEITHEIIGFLDQTLYRWNRLGIESP---R 542 human XP_007497985 470 AVAGESSE--DGTRQPStQRFIRHLLLNFLLFSSEGHTIAQEFI--ITQTDEIIDEFLNLIARAKSRWERLGMETP---R 542 gray short-tail... XP_008101427 470 VVT--SSR--IDARCPGtKHLIRHLIVSFLLFTPGGHTIAREFIDGFAVGSSEILEVIGLLTCISNRVSQDGVKYQ---R 542 green anole XP_002194329 471 AAVHRVT----GTEQCCnQQFTTHLLTNFLLFSPGGHKIAQECIYHITEITDTSKEVHNLLIRTAYRFNHSGEENQ---R 543 zebra finch XP_015135800 471 ASVNNAA----DTEQCHtQCLITHLLTNFLLFSSGGHMIAQEFISHITETTDMSKEVCSLLIRTAYRIKHNGGENQ---R 543 chicken XP_023199100 487 SFISLLAP--KPQQPSLaPSLTLSLLVNFATFGQLPQSISAEITQKVVHQSGLQDEATRVLSSLRLRLNDRGSFANd--R 562 southern platyfish XP_005452188 488 SLVTLVSP--QPEQQSLaPSLTVSLLVNVAVFCQLPPSGSAEVLQAVVDQSGLLDEAACVLSSLELRLNEGSCLSRd--T 563 Nile tilapia XP_022526809 481 PVQELLSS-------MFsTNLVLHLLLNFAVFSQASASSVSEVIQKLLMEAGMRRKAAWILSSVQHRLNRADLLDA---R 550 Mexican tetra XP_005167236 469 AVKELLSS------SSIsANLVLHLFSNFAVFSHGPVSIITEISDKVLTETAVRRRALWILASIRCRLNSASSRDD---R 539 zebrafish
XP_011613892 573 VQLRVQKLQHTLT 585 torafugu Q00597 543 SEKLARELLKELR 555 human XP_007497985 543 TGKLARDLLQELQ 555 gray short-tailed opossum XP_008101427 543 TIKLANDLLQRLK 555 green anole XP_002194329 544 TVKLLNELLQKLT 556 zebra finch XP_015135800 544 TVKLLNELLQKLA 556 chicken XP_023199100 563 VHLRIEELHNTIK 575 southern platyfish XP_005452188 564 VHLRIKELQKTIt 576 Nile tilapia XP_022526809 551 VHSRLKTLQDSLA 563 Mexican tetra XP_005167236 540 VHSRLRTLQDTLL 552 zebrafish
Jiyao W et al.(2023). "The conserved domain database in 2023.",