6KN7


Conserved Protein Domain Family
Troponin
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pfam00992: Troponin (this model, PSSM-Id:395788 is obsolete and has been replaced by 460018)
Troponin
Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). this Pfam contains members of the TnT subunit. Troponin is a complex of three proteins, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). The troponin complex regulates Ca++ induced muscle contraction. This family includes troponin T and troponin I. Troponin I binds to actin and troponin T binds to tropomyosin.
Links
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Statistics
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PSSM-Id: 395788
Aligned: 87 rows
Threshold Bit Score: 40.5826
Created: 22-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6KN7_T          7 KRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR-AeraEQQRIRNEREKERQNRLAEERARREEEENRRKAEDE 85 
ACH53100       20 KRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRaEr-aEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDD 98  small-eared ga...
24_pfamImport   1 KRLEKDFNELQSLIEMHFESRQKEEDELVALKLRIERRRsEr-aEQLRIRTEREKERQTRMTEEKLRKEEEEARRKAEED 79 
Q8AVB1        101 KRVEKDFNELQSLINLHFTTRQKEEDELVALKNRIERRRtDr-aDQQRIRTERDRERQARLAEERARREEEAAKLRAEED 179 zebrafish
1_pfamImport    1 RRLEKDFDDLQTLIESHFSARQKEEEELLALRGRIERRRsDr-aEQQRVRAERERERAARLAGERARREEEAAA----ND 75 
XP_012019000   60 KRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRaEr-aEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDD 138 mouflon
CAG02062       71 KRMEKDLLELQTLIDVHFDQRKKDEEELISLKERIERRRaEr-aEIQRVRAEKEKDRQNRIAEERHRKEEEEAKKKADDE 149 spotted green ...
NP_001103886   93 KRQNKDLVELQALIDAHFEHRKKEEEELIALKDRIEKRRsEr-aEQQRIRAEKDKERQARREEERLRKEEADAKKRADED 171 zebrafish
CAG12485      140 KRQNKDLIELQSLIDAHFECRKKEEEELIALKERIEKRRaEr-aEQQRIRAERDKERQARREAERQRKEEADAHRKAEDE 218 spotted green ...
PWA21945       81 KRMEKDLLELQTLIDVHFEQRKKEEEELIGLKDRIERRRaEr-aEQQRVRAEKERDRQTRIAEERQRKEDEEAKKRADDE 159 western mosqui...

6KN7_T         86 ARKKKALSNMMH-FGGYIQKqaqterksGKRQTEREKKKKILAERRK-VlAIDHLNEDQLRE 145
ACH53100       99 LKKKKALSSMGAnYSSYLAKadq---krGKKQTAREMKKKILAERRKpL-NIDHLSDDKLRD 156 small-eared galago
24_pfamImport  80 AKKKKAFSNMs--FGGYLQKvek---kaGKKLTEREKKTKILKERRRpL-NIDHLNQEKLAE 135
Q8AVB1        180 ARKKKILSNKg--YGGFLQKvdq---kkGKKLTEREKKTKCLLERRKpL-NIDHLNQEKLGE 235 zebrafish
1_pfamImport   76 AKKKKTFTSKs--FGGY-QKadq---rkSKKLTAREEKKKALTERRRpL-NIDHLSQEKLAD 130
XP_012019000  139 AKKKKVLSNMGAhFGGYLVKaeq---krGKRQTGREMKVRILSERKKpL-NIDHMGEEQLRE 196 mouflon
CAG02062      150 AKKKKVLSGMGAnFGGFLAKaet---rkGKRFTGREIKKKTLAERRQpL-AIDSLREDGLRQ 207 spotted green pufferfish
NP_001103886  172 AKKKSALSNMGSqYSSYLQKads--krgGKKQTEREKKKKILAERRKpL-NIDHMNEDKLRE 230 zebrafish
CAG12485      219 AKKKIALSNMGSgYSSILQRaeq---krGKRLTEREKKKKIMADRVKpL-NVDNLSDDKLRE 276 spotted green pufferfish
PWA21945      160 AKKKKVLSNMGAhFGGFLAKeeq---rrGKRQTAREIKKKTLAERRKpL-SIESLKEDGLR- 216 western mosquitofish
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