nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nfkbizprovided by ZNC
Official Full Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zetaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-071024-1
See related: Ensembl:ENSDARG00000102097 AllianceGenome:ZFIN:ZDB-GENE-071024-1
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable DNA binding activity and POU domain binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in membrane. Predicted to be active in nucleus. Orthologous to human NFKBIZ (NFKB inhibitor zeta). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (18631..23837)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (18663..23838)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

fk75f05.x1 (e-PCR)
- UniSTS:201507

G45085 (e-PCR)
- UniSTS:105887

G47419 (e-PCR)
- UniSTS:108198

G40533 (e-PCR)
- UniSTS:16600

fk89h09.x1 (e-PCR)
- UniSTS:201690

z728 (e-PCR), detects polymorphism
- UniSTS:204769

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables POU domain binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of gene expression	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: NF-kappa-B inhibitor zeta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007112.7 Reference GRCz11 Primary Assembly

Range

18631..23837

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021475911.2 → XP_021331586.1 NF-kappa-B inhibitor zeta

UniProtKB/TrEMBL

A0A8M9Q7W9

Related

ENSDARP00000130393.1, ENSDART00000172454.1

Conserved Domains (3) summary

cd00204
Location:252 → 383

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

sd00045
Location:364 → 418

ANK; ANK repeat [structural motif]

cl26072
Location:452 → 516

Ank_5; Ankyrin repeats (many copies)