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htra2-3 HtrA serine peptidase 2-3 [ Danio rerio (zebrafish) ]

Gene ID: 100003308, updated on 12-Sep-2024

Summary

Official Symbol
htra2-3provided by ZNC
Official Full Name
HtrA serine peptidase 2-3provided by ZNC
Primary source
ZFIN:ZDB-GENE-081028-21
See related
Ensembl:ENSDARG00000092061 AllianceGenome:ZFIN:ZDB-GENE-081028-21
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-112g5.13
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in positive regulation of apoptotic process; programmed cell death; and proteolysis. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See htra2-3 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (9074789..9091276, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (8742766..8759253, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene HtrA serine peptidase 2-1 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 151 Neighboring gene serine/threonine-protein kinase pim-2-like Neighboring gene si:busm1-sl7.7

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in positive regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in programmed cell death IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein LOC100003308
Names
serine protease HTRA2, mitochondrial-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109735.2NP_001103205.2  uncharacterized protein LOC100003308

    Status: VALIDATED

    Source sequence(s)
    CT025775
    Related
    ENSDARP00000117525.1, ENSDART00000142697.3

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    9074789..9091276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394865.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    88787..105274 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)