rnaseh2c ribonuclease H2, subunit C [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rnaseh2cprovided by ZNC
Official Full Name: ribonuclease H2, subunit Cprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2469
See related: Ensembl:ENSDARG00000089637 AllianceGenome:ZFIN:ZDB-GENE-030131-2469
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc08g11; im:5617510; wu:fc08g11; si:dkey-147f20.5
Summary: Predicted to be involved in RNA catabolic process. Predicted to be part of ribonuclease H2 complex. Is expressed in female organism. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human RNASEH2C (ribonuclease H2 subunit C). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (35409322..35414555, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (35069008..35074241, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in RNA catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within RNA catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of ribonuclease H2 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonuclease H2 complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ribonuclease H2 subunit C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001161377.1 → NP_001154849.1 ribonuclease H2 subunit C

Status: PROVISIONAL

Source sequence(s)

CR626866

UniProtKB/TrEMBL

A0A8M1NRR3, E9QD20

Related

ENSDARP00000123155.1, ENSDART00000145033.3

Conserved Domains (1) summary

cd09271
Location:25 → 109

RNase_H2-C; Ribonuclease H2-C is a subunit of the eukaryotic RNase H complex which cleaves RNA-DNA hybrids