sh3bp1 SH3-domain binding protein 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sh3bp1provided by ZNC
Official Full Name: SH3-domain binding protein 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-121128-2
See related: Ensembl:ENSDARG00000078119 AllianceGenome:ZFIN:ZDB-GENE-121128-2
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of small GTPase mediated signal transduction; regulation of Rac protein signal transduction; and regulation of actin cytoskeleton organization. Predicted to act upstream of or within positive regulation of GTPase activity and signal transduction. Predicted to be located in cytoplasm. Predicted to be active in cytosol and plasma membrane. Orthologous to human SH3BP1 (SH3 domain binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (19207530..19237114)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (19086491..19111050)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables GTPase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of small GTPase mediated signal transduction	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info
involved_in regulation of Rac protein signal transduction	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of actin cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain