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senp1 SUMO specific peptidase 1 [ Danio rerio (zebrafish) ]

Gene ID: 100007636, updated on 2-Nov-2024

Summary

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Official Symbol
senp1provided by ZNC
Official Full Name
SUMO specific peptidase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6462
See related
Ensembl:ENSDARG00000078574 AllianceGenome:ZFIN:ZDB-GENE-030131-6462
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj98g07; wu:fj98g07; si:dkey-21c19.3
Summary
Predicted to enable deSUMOylase activity. Predicted to be involved in protein desumoylation. Predicted to act upstream of or within proteolysis. Predicted to be active in nucleus. Orthologous to human SENP1 (SUMO specific peptidase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See senp1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (25769757..25780001, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (25843213..25853508, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor-related protein 1Ab Neighboring gene somatostatin receptor type 3-like Neighboring gene RNA binding motif, single stranded interacting protein 2b Neighboring gene uncharacterized LOC110439122 Neighboring gene fat storage inducing transmembrane protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables deSUMOylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein desumoylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sentrin-specific protease 1
XP_001343517.1
XP_021329374.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    25769757..25780001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001343481.9 → XP_001343517.1  sentrin-specific protease 1

    UniProtKB/TrEMBL
    A0A8M1Q260, E7F9B8
    Related
    ENSDARP00000103287.3, ENSDART00000110670.4
    Conserved Domains (1) summary
    cl23802
    Location:490 → 726
    Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395153.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    195743..206037 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473699.2 → XP_021329374.1  sentrin-specific protease 1

    UniProtKB/TrEMBL
    A0A8M9PWZ7
    Conserved Domains (1) summary
    COG5160
    Location:505 → 728
    ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein Strain
Heading Accession and Version

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