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hsp70.1 heat shock cognate 70-kd protein, tandem duplicate 1 [ Danio rerio (zebrafish) ]

Gene ID: 100126123, updated on 17-Sep-2024

Summary

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Official Symbol
hsp70.1provided by ZNC
Official Full Name
heat shock cognate 70-kd protein, tandem duplicate 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-990415-91
See related
Ensembl:ENSDARG00000029688 AllianceGenome:ZFIN:ZDB-GENE-990415-91
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hsp70; hspa1a; hsp70-4
Summary
Predicted to enable ATP binding activity. Acts upstream of or within several processes, including camera-type eye morphogenesis; response to cadmium ion; and response to heat. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including gill; gonad; lens; liver; and solid lens vesicle. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See hsp70.1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (26112785..26115539, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (25981905..25984742, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490597 Neighboring gene uncharacterized LOC137490006 Neighboring gene forkhead box D7 Neighboring gene heat shock cognate 70-kd protein, tandem duplicate 2 Neighboring gene heat shock cognate 70-kd protein, tandem duplicate 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Holographic optical tweezers-based in vivo manipulations in zebrafish embryos. Hörner F, et al. J Biophotonics, 2017 Nov. PMID 28164445
  2. Characterization of the heat shock response in mature zebrafish (Danio rerio). Murtha JM, et al. Exp Gerontol, 2003 Jun. PMID 12814804
  3. Suppression of heat shock transcription factor HSF1 in zebrafish causes heat-induced apoptosis. Wang G, et al. Genesis, 2001 Jul. PMID 11477707
  4. Heat-inducible expression of a reporter gene detected by transient assay in zebrafish. Adám A, et al. Exp Cell Res, 2000 Apr 10. PMID 10739675
  5. Stressor-dependent regulation of the heat shock response in zebrafish, Danio rerio. Airaksinen S, et al. Comp Biochem Physiol A Mol Integr Physiol, 2003 Apr. PMID 12814792

See all (55) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within camera-type eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to cadmium ion IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to heat IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to xenobiotic stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
heat shock cognate 70-kd protein, tandem duplicate 1
Names
etID309743.10
heat shock cognate 70-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362359.1 → NP_001349288.1  heat shock cognate 70-kd protein, tandem duplicate 1

    Status: VALIDATED

    Source sequence(s)
    FP016243
    UniProtKB/TrEMBL
    B0UXS6, B1H1L1
    Related
    ENSDARP00000109199.2, ENSDART00000124762.3
    Conserved Domains (1) summary
    cl26953
    Location:5 → 643
    HSP70; Hsp70 protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    26112785..26115539 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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