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fbxw8 F-box and WD repeat domain containing 8 [ Danio rerio (zebrafish) ]

Gene ID: 100136859, updated on 2-Nov-2024

Summary

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Official Symbol
fbxw8provided by ZNC
Official Full Name
F-box and WD repeat domain containing 8provided by ZNC
Primary source
ZFIN:ZDB-GENE-080204-111
See related
Ensembl:ENSDARG00000079089 AllianceGenome:ZFIN:ZDB-GENE-080204-111
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:172294
Summary
Orthologous to human FBXW8 (F-box and WD repeat domain containing 8). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See fbxw8 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (11864312..11905933, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (11364208..11405703, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor a Neighboring gene F-box protein 21 Neighboring gene tescalcin a Neighboring gene ring finger protein, transmembrane 2 Neighboring gene SREBF pathway regulator in golgi 1 Neighboring gene oncostatin M

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  

General protein information

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Preferred Names
F-box/WD repeat-containing protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114578.1 → NP_001108050.1  F-box/WD repeat-containing protein 8

    See identical proteins and their annotated locations for NP_001108050.1

    Status: PROVISIONAL

    Source sequence(s)
    BC155644
    UniProtKB/TrEMBL
    A9JRF9
    Related
    ENSDARP00000101492.2, ENSDART00000114378.4
    Conserved Domains (4) summary
    COG2319
    Location:300 → 626
    WD40; WD40 repeat [General function prediction only]
    pfam12937
    Location:138 → 182
    F-box-like; F-box-like
    sd00039
    Location:411 → 454
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:221 → 525
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    11864312..11905933 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021475977.2 → XP_021331652.1  F-box/WD repeat-containing protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PJL4
    Conserved Domains (3) summary
    sd00039
    Location:234 → 273
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:138 → 180
    F-box-like
    cl25539
    Location:221 → 479
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein Strain
Heading Accession and Version

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