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btbd6a BTB (POZ) domain containing 6a [ Danio rerio (zebrafish) ]

Gene ID: 100141360, updated on 28-Oct-2024

Summary

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Official Symbol
btbd6aprovided by ZNC
Official Full Name
BTB (POZ) domain containing 6aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080218-26
See related
Ensembl:ENSDARG00000076440 AllianceGenome:ZFIN:ZDB-GENE-080218-26
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
btbd6b; zgc:172197
Summary
Acts upstream of or within regulation of neurogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Is expressed in nervous system; neuroblasts; posterior neural keel; posterior neural plate; and spinal cord neural tube. Orthologous to human BTBD6 (BTB domain containing 6). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See btbd6a in Genome Data Viewer
Location:
chromosome: 13
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (33394113..33399828, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (33263661..33269370, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110440192 Neighboring gene zgc:172120 Neighboring gene BRF1 general transcription factor IIIB subunit a Neighboring gene finTRIM family, member 80 Neighboring gene finTRIM family, member 81

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation. Sobieszczuk DF, et al. Genes Dev, 2010 Jan 15. PMID 20080956, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
  
involved_in neurogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of neurogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of neurogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
BTB/POZ domain-containing protein 6-A
Names
BTB/POZ domain-containing protein 6-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114925.2 → NP_001108397.2  BTB/POZ domain-containing protein 6-A isoform 1

    Status: VALIDATED

    Source sequence(s)
    CU855940
    Related
    ENSDARP00000146109.1, ENSDART00000182601.1

  2. NM_001431077.1 → NP_001418006.1  BTB/POZ domain-containing protein 6-A isoform 2

    Status: VALIDATED

    Source sequence(s)
    CU855940
    UniProtKB/TrEMBL
    A0A8M2BHZ5

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    33394113..33399828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A9JRD8.2 GenPept UniProtKB/Swiss-Prot:A9JRD8

Gene LinkOut

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