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ankrd6a ankyrin repeat domain 6a [ Danio rerio (zebrafish) ]

Gene ID: 100330565, updated on 2-Nov-2024

Summary

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Official Symbol
ankrd6aprovided by ZNC
Official Full Name
ankyrin repeat domain 6aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-120525-1
See related
Ensembl:ENSDARG00000057790 AllianceGenome:ZFIN:ZDB-GENE-120525-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to be involved in negative regulation of canonical Wnt signaling pathway and positive regulation of JNK cascade. Predicted to be active in cytoplasm and nucleus. Orthologous to human ANKRD6 (ankyrin repeat domain 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See ankrd6a in Genome Data Viewer
Location:
chromosome: 17
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (15757067..15777938, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (15749248..15764640, complement)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene mannosidase, endo-alpha Neighboring gene BTB and CNC homology 1, basic leucine zipper transcription factor 2a Neighboring gene gap junction protein alpha 10 a Neighboring gene ras-related GTP binding D Neighboring gene gamma-aminobutyric acid type A receptor subunit rho2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The spatial-temporal expression and functional divergence of bach homologs in zebrafish Danio rerio. Luo Q, et al. J Fish Biol, 2016 Apr. PMID 26992035
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of JNK cascade IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ankyrin repeat domain-containing protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    15757067..15777938 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021467385.2 → XP_021323060.1  ankyrin repeat domain-containing protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PPE8
    Conserved Domains (3) summary
    cd00204
    Location:30 → 155
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:69 → 99
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:139 → 201
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_021467384.2 → XP_021323059.1  ankyrin repeat domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PES1
    Related
    ENSDARP00000129384.1, ENSDART00000155711.3
    Conserved Domains (3) summary
    cd00204
    Location:30 → 155
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:69 → 99
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:139 → 201
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
Heading Accession and Version

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