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peli3 pellino E3 ubiquitin protein ligase family member 3 [ Danio rerio (zebrafish) ]

Gene ID: 100331601, updated on 2-Nov-2024

Summary

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Official Symbol
peli3provided by ZNC
Official Full Name
pellino E3 ubiquitin protein ligase family member 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-110304-4
See related
Ensembl:ENSDARG00000087452 AllianceGenome:ZFIN:ZDB-GENE-110304-4
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to act upstream of or within protein polyubiquitination and regulation of Toll signaling pathway. Orthologous to human PELI3 (pellino E3 ubiquitin protein ligase family member 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See peli3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (18122352..18168417, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (17870087..17916173, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene si:ch73-40a2.1 Neighboring gene zRAB1B, member RAS oncogene family a Neighboring gene uncharacterized LOC137496162 Neighboring gene Ras converting CAAX endopeptidase 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Cd248a and Cd248b in zebrafish participate in innate immune responses. Li X, et al. Front Immunol, 2022. PMID 36119065, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of Toll signaling pathway IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
E3 ubiquitin-protein ligase pellino homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    18122352..18168417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021477739.2 → XP_021333414.1  E3 ubiquitin-protein ligase pellino homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q8E1, E7F7M5
    Related
    ENSDARP00000108458.1, ENSDART00000127428.4
    Conserved Domains (1) summary
    pfam04710
    Location:44 → 477
    Pellino; Pellino

  2. XM_068222571.1 → XP_068078672.1  E3 ubiquitin-protein ligase pellino homolog 1 isoform X2

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394682.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    645..61536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002662799.7 → XP_002662845.2  E3 ubiquitin-protein ligase pellino homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q8E1, E7F7M5
    Conserved Domains (1) summary
    pfam04710
    Location:44 → 477
    Pellino; Pellino
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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