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larp4aa La ribonucleoprotein 4Aa [ Danio rerio (zebrafish) ]

Gene ID: 100332095, updated on 28-Oct-2024

Summary

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Official Symbol
larp4aaprovided by ZNC
Official Full Name
La ribonucleoprotein 4Aaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090313-50
See related
Ensembl:ENSDARG00000078401 AllianceGenome:ZFIN:ZDB-GENE-090313-50
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-156j22.2
Summary
Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in positive regulation of translation. Predicted to be active in cytoplasmic stress granule and cytosol. Orthologous to human LARP4 (La ribonucleoprotein 4). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See larp4aa in Genome Data Viewer
Location:
chromosome: 23
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (27509029..27548227, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene activating transcription factor 7a Neighboring gene ankyrin repeat and SOCS box containing 8 Neighboring gene phosphofructokinase, muscle a Neighboring gene trophinin associated protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007134.7 Chromosome 23 Reference GRCz11 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
La ribonucleoprotein 4Aa; la ribonucleoprotein 4Aa
Names
La ribonucleoprotein domain family, member 4Aa
la-related protein 4
larp4a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001423566.1 → NP_001410495.1  La ribonucleoprotein 4Aa

    Status: VALIDATED

    Source sequence(s)
    CR354381
    UniProtKB/TrEMBL
    A0A8M1RI22

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    27509029..27548227 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009296950.4 → XP_009295225.1  la ribonucleoprotein 4Aa isoform X1

    UniProtKB/TrEMBL
    A0A8M3AYK9, E9QDP4
    Related
    ENSDARP00000119719.1, ENSDART00000144419.3
    Conserved Domains (2) summary
    cd08035
    Location:145 → 219
    LARP_4; La RNA-binding domain of La-related protein 4
    cd12707
    Location:224 → 300
    RRM_LARP4; RNA recognition motif in vertebrate La-related protein 4 (LARP4)
Nucleotide Protein Strain
Heading Accession and Version

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