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tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) [ Danio rerio (zebrafish) ]

Gene ID: 100333043, updated on 2-Nov-2024

Summary

Official Symbol
tap1provided by ZNC
Official Full Name
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)provided by ZNC
Primary source
ZFIN:ZDB-GENE-050517-43
See related
Ensembl:ENSDARG00000079766 AllianceGenome:ZFIN:ZDB-GENE-050517-43
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable ABC-type peptide transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in several diseases, including MHC class I deficiency; autoimmune disease (multiple); bronchial disease (multiple); diffuse scleroderma; and lung disease (multiple). Orthologous to human TAP1 (transporter 1, ATP binding cassette subfamily B member). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See tap1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (48678689..48705831)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (48736649..48763813)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene pre-B-cell leukemia homeobox 2 Neighboring gene uncharacterized LOC137487984 Neighboring gene notch receptor, like Neighboring gene bromodomain containing 2b Neighboring gene si:ch73-31d8.2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ABC-type peptide transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
antigen peptide transporter 1
Names
abcb2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    48678689..48705831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002665007.4XP_002665053.1  antigen peptide transporter 1

    UniProtKB/TrEMBL
    A0A8M1RMC7, E7F8A9
    Related
    ENSDARP00000124923.1, ENSDART00000150156.3
    Conserved Domains (3) summary
    TIGR00958
    Location:42712
    3a01208; Conjugate Transporter-2 (CT2) Family protein
    pfam00664
    Location:166433
    ABC_membrane; ABC transporter transmembrane region
    cl21455
    Location:467692
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases