gipr gastric inhibitory polypeptide receptor [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: giprprovided by ZNC
Official Full Name: gastric inhibitory polypeptide receptorprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050516-4
See related: Ensembl:ENSDARG00000025478 AllianceGenome:ZFIN:ZDB-GENE-050516-4
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-188j1.2
Summary: Predicted to enable G protein-coupled peptide receptor activity; gastric inhibitory peptide receptor activity; and peptide hormone binding activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in cardiovascular system disease; diabetes mellitus; obesity; and type 2 diabetes mellitus. Orthologous to human GIPR (gastric inhibitory polypeptide receptor). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (28940573..28978763)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (29007262..29041186)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables G protein-coupled peptide receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables gastric inhibitory peptide receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables gastric inhibitory peptide receptor activity	IEA Inferred from Electronic Annotation more info
enables peptide hormone binding	IBA Inferred from Biological aspect of Ancestor more info
enables transmembrane signaling receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell surface receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_005157739.5 → XP_005157796.1 gastric inhibitory polypeptide receptor isoform X1

See identical proteins and their annotated locations for XP_005157796.1

UniProtKB/TrEMBL

A0A8M2B409, E7FCX8

Related

ENSDARP00000038331.7, ENSDART00000029459.8

Conserved Domains (2) summary

pfam00002
Location:139 → 392

7tm_2; 7 transmembrane receptor (Secretin family)

pfam02793
Location:52 → 121

HRM; Hormone receptor domain
XM_009291758.4 → XP_009290033.1 gastric inhibitory polypeptide receptor isoform X2

UniProtKB/TrEMBL

A0A8M3B170, X1WDQ9

Related

ENSDARP00000128358.1, ENSDART00000154085.3

Conserved Domains (2) summary

pfam00002
Location:124 → 377

7tm_2; 7 transmembrane receptor (Secretin family)

pfam02793
Location:52 → 106

HRM; Hormone receptor domain
XM_068213748.1 → XP_068069849.1 gastric inhibitory polypeptide receptor isoform X3